-
1
-
-
0017701219
-
Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol
-
Abuchoswki, A., Van, E., Palczuk, N.C., et al. (1977) Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol. J. Biol. Chem. 252, 3578-3581.
-
(1977)
J. Biol. Chem
, vol.252
, pp. 3578-3581
-
-
Abuchoswki, A.1
Van, E.2
Palczuk, N.C.3
-
2
-
-
75649099024
-
PEGylation of therapeutic proteins
-
Jevševar, S., Kunstelj, M., Gaberc Porekar, V. (2010) PEGylation of therapeutic proteins. J. Biotechnol. 5, 113-128.
-
(2010)
J. Biotechnol
, vol.5
, pp. 113-128
-
-
Jevševar, S.1
Kunstelj, M.2
Gaberc Porekar, V.3
-
3
-
-
51549092094
-
The impact of PEGylation on biological therapies
-
Mero, A., Veronese, F.M. (2008) The impact of PEGylation on biological therapies. Biodrugs 22, 315-329.
-
(2008)
Biodrugs
, vol.22
, pp. 315-329
-
-
Mero, A.1
Veronese, F.M.2
-
4
-
-
0029265458
-
Functionalized poly (Ethylene glycol) for preparation of biologically relevant conjugates
-
Zalipsky, S. (1995) Functionalized poly (ethylene glycol) for preparation of biologically relevant conjugates. Bioconjug. Chem. 6, 150-165.
-
(1995)
Bioconjug. Chem
, vol.6
, pp. 150-165
-
-
Zalipsky, S.1
-
5
-
-
0035284411
-
Peptide and protein PEGylation: A review of problems and solutions
-
Veronese, F.M. (2001) Peptide and protein PEGylation: a review of problems and solutions. Biomaterials 22, 405-417.
-
(2001)
Biomaterials
, vol.22
, pp. 405-417
-
-
Veronese, F.M.1
-
6
-
-
0016636179
-
An improved 2,4,6,-trinitrobenzenesulfonic acid method for the determination of amines
-
Snyder, S. L. and Sobocinski, P. Z. (1975) An improved 2,4,6,-trinitrobenzenesulfonic acid method for the determination of amines. Anal. Biochem. 64, 284-288.
-
(1975)
Anal. Biochem
, vol.64
, pp. 284-288
-
-
Snyder, S.L.1
Sobocinski, P.Z.2
-
7
-
-
0018416496
-
Ellman’s reagent: 5,5’-dithiobis(2-nitrobenzoic acid) a reexaminatio
-
Riddles, P.W., Blakeley, R. L., and Zarner, B. (1979) Ellman’s reagent: 5,5’-dithiobis(2-nitrobenzoic acid) a reexaminatio. Anal. Biochem. 94, 75-81.
-
(1979)
Anal. Biochem
, vol.94
, pp. 75-81
-
-
Riddles, P.W.1
Blakeley, R.L.2
Zarner, B.3
-
8
-
-
85020940275
-
-
www.laysanbio.com
-
-
-
-
9
-
-
0035246226
-
Mass spectrometry of polymers and polymer surfaces
-
Hanton, S. D. (2001) Mass spectrometry of polymers and polymer surfaces. Chem. Rev. 101, 527-570.
-
(2001)
Chem. Rev
, vol.101
, pp. 527-570
-
-
Hanton, S.D.1
-
10
-
-
0347835984
-
-
Academic Press, New York
-
Vestling, M. M., Murphy, C. M., Fenselau, C., Dedinas, J., Doleman, M. S., Harrsch, P. B., Kutny, R., Ladd, D. L., and Olsen, M. A. (1992) Techniques in Protein Chemistry III, Academic Press, New York, pp. 477-485.
-
(1992)
Techniques in Protein Chemistry III
, pp. 477-485
-
-
Vestling, M.M.1
Murphy, C.M.2
Fenselau, C.3
Dedinas, J.4
Doleman, M.S.5
Harrsch, P.B.6
Kutny, R.7
Ladd, D.L.8
Olsen, M.A.9
-
11
-
-
0027427134
-
A strategy for characterization of polyethylene glycol-derivatized proteins: A mass spectrometric analysis of the attachment sites in polyethylene glycol-derivatized superoxide dismutase
-
Vestling, M. M., Murphy, C. M., Keller, D. A., Fenselau, C., Dedinas, J., Ladd, D. L., and Olsen, M. A. (1993) A strategy for characterization of polyethylene glycol-derivatized proteins: a mass spectrometric analysis of the attachment sites in polyethylene glycol-derivatized superoxide dismutase. Drug Metab. Dispos. 21, 911-917.
-
(1993)
Drug Metab. Dispos
, vol.21
, pp. 911-917
-
-
Vestling, M.M.1
Murphy, C.M.2
Keller, D.A.3
Fenselau, C.4
Dedinas, J.5
Ladd, D.L.6
Olsen, M.A.7
-
12
-
-
85020915614
-
Characterization of synthetic polymers by MALDI-MS
-
Montaudo, G., Samperi, F., Montaudo, M. S. (2006) Characterization of synthetic polymers by MALDI-MS. Prog. Polym. Sci. 10, 1016-1020.
-
(2006)
Prog. Polym. Sci
, vol.10
, pp. 1016-1020
-
-
Montaudo, G.1
Samperi, F.2
Montaudo, M.S.3
-
13
-
-
85020910611
-
Mass spectrometric analyses of potential impurities in 20 kDa monomethoxy poly (Ethylene glycol)-propionaldehyde (PEG aldehyde) raw material
-
Zhang H., Zhang, J., Luo, Y., Wilson, J., and Miller, K. (2007) Mass spectrometric analyses of potential impurities in 20 kDa monomethoxy poly (ethylene glycol)-propionaldehyde (PEG aldehyde) raw material. AAPS Annual Meeting & Exposition.
-
(2007)
AAPS Annual Meeting & Exposition
-
-
Zhang, H.1
Zhang, J.2
Luo, Y.3
Wilson, J.4
Miller, K.5
-
14
-
-
0037379147
-
Proton NMR study of chemically modified horse heart ferricytochrome C confirms the presence of histidine and lysine-ligated conformers in 30% acetonitrile solution
-
Sivakolundu, S. G., and Mabrouk, P. A. (2003) Proton NMR study of chemically modified horse heart ferricytochrome C confirms the presence of histidine and lysine-ligated conformers in 30% acetonitrile solution. J. Inorg. Biochem. 94, 381-385.
-
(2003)
J. Inorg. Biochem
, vol.94
, pp. 381-385
-
-
Sivakolundu, S.G.1
Mabrouk, P.A.2
-
15
-
-
0032832218
-
An unusual coupling of poly(Ethylene glycol) to tyrosine residues in epidermal growth factor
-
Orsatti, L. and Veronese, F. M. (1999) An unusual coupling of poly(ethylene glycol) to tyrosine residues in epidermal growth factor. J. Bioact. Compat. Pol. 14, 429-436.
-
(1999)
J. Bioact. Compat. Pol
, vol.14
, pp. 429-436
-
-
Orsatti, L.1
Veronese, F.M.2
-
16
-
-
0034848092
-
Carboxyalkylated histidine is a pHdependent product of PEGylation with SC-PEG
-
Wylie, D. C., Voloch, M., Lee, S., Liu, Y. H., Cannon-Carlson, S., Cutler, C., Pramanik, B. (2001) Carboxyalkylated histidine is a pHdependent product of PEGylation with SC-PEG. Pharm Res. 18, 1354-1360.
-
(2001)
Pharm Res
, vol.18
, pp. 1354-1360
-
-
Wylie, D.C.1
Voloch, M.2
Lee, S.3
Liu, Y.H.4
Cannon-Carlson, S.5
Cutler, C.6
Pramanik, B.7
-
17
-
-
0029759584
-
Charecterization and stability of N-Terminally PEGylated rhG-CSF
-
Kinstler, O. B., Brems, D. N., Lauren, S. L., Paige, A. G., Hamburger, J. B. and Treuheit, M. J. (1996) Charecterization and stability of N-Terminally PEGylated rhG-CSF. Pharm. Res. 13, 996-1002.
-
(1996)
Pharm. Res
, vol.13
, pp. 996-1002
-
-
Kinstler, O.B.1
Brems, D.N.2
Lauren, S.L.3
Paige, A.G.4
Hamburger, J.B.5
Treuheit, M.J.6
-
18
-
-
0242584999
-
N-Terminal site-specific mono- PEGylation of epidermal growth factor
-
Lee, H., Jang, I. H., Ryu, S. H., and Pack, T.G. (2003) N-Terminal site-specific mono- PEGylation of epidermal growth factor. Pharm. Res. 20, 818-825.
-
(2003)
Pharm. Res
, vol.20
, pp. 818-825
-
-
Lee, H.1
Jang, I.H.2
Ryu, S.H.3
Pack, T.G.4
-
19
-
-
0037124498
-
Mono-N-terminal poly(Ethyleneglycol)-protein conjugates
-
Kinstler, O., Molineux, G., Treuheit, M., Ladd, D. et al. (2002) Mono-N-terminal poly(ethyleneglycol)-protein conjugates. Adv. Drug Deliv. Rev. 54, 477-485.
-
(2002)
Adv. Drug Deliv. Rev
, vol.54
, pp. 477-485
-
-
Kinstler, O.1
Molineux, G.2
Treuheit, M.3
Ladd, D.4
-
20
-
-
0027138673
-
Cysteine 17 of recombinant human granulocyte-colony stimulating factor is partially solvent-exposed
-
Arakawa, T., Prestrelski, S. J., Narhi, L. O., Boone, T. C., Kenney, W. C. (1993) Cysteine 17 of recombinant human granulocyte-colony stimulating factor is partially solvent-exposed. J. Protein Chem. 12, 525-531.
-
(1993)
J. Protein Chem
, vol.12
, pp. 525-531
-
-
Arakawa, T.1
Prestrelski, S.J.2
Narhi, L.O.3
Boone, T.C.4
Kenney, W.C.5
-
21
-
-
44449150161
-
Site-directed PEGylation as successful approach to improve the enzyme replacement in the case of prolidase
-
Colonna, C., Conti, B., Perugini, P., Pavanetto, F., Modena, T., Dorati, R., Iadarola, P., Genta, I. (2008) Site-directed PEGylation as successful approach to improve the enzyme replacement in the case of prolidase. Int. J. Pharm. 24, 230-237.
-
(2008)
Int. J. Pharm
, vol.24
, pp. 230-237
-
-
Colonna, C.1
Conti, B.2
Perugini, P.3
Pavanetto, F.4
Modena, T.5
Dorati, R.6
Iadarola, P.7
Genta, I.8
-
22
-
-
0033605042
-
Site-directed polyethylene glycol modification of trichosanthin: Effects on its biological activities, pharmacokinetics, and antigenicity
-
Xian-Hui, H., Pang-Chui, S., Li-Hui, X., and Siu-Cheung, T. (1999) Site-directed polyethylene glycol modification of trichosanthin: Effects on its biological activities, pharmacokinetics, and antigenicity. Life Sic. 64, 1163-1175.
-
(1999)
Life Sic
, vol.64
, pp. 1163-1175
-
-
Xian-Hui, H.1
Pang-Chui, S.2
Li-Hui, X.3
Siu-Cheung, T.4
-
23
-
-
33846406038
-
Site-Specific PEGylation of Protein Disulfide Bonds Using a Three-Carbon Bridge
-
Balan, S., Choi, J., Godwin, A., Teo, I., Laborde, C. M., Heidelberger, S., Zloh, M., Shaunak, S., and Brocchini, S. (2007) Site-Specific PEGylation of Protein Disulfide Bonds Using a Three-Carbon Bridge. Bioconjug. Chem. 18, 61-76.
-
(2007)
Bioconjug. Chem
, vol.18
, pp. 61-76
-
-
Balan, S.1
Choi, J.2
Godwin, A.3
Teo, I.4
Laborde, C.M.5
Heidelberger, S.6
Zloh, M.7
Shaunak, S.8
Brocchini, S.9
-
24
-
-
0346540565
-
Hydrazide derivatives of polyethylene glycol and their bioconjugates
-
Harris, J. M and Zalipsky, S. eds
-
Zalipsky, S., and Meno-Rudolph, S. (1997) Hydrazide derivatives of polyethylene glycol and their bioconjugates. In Polyethylene glycol chemistry and biological applications, ACS symposium series 680 (Harris, J. M., and Zalipsky, S. eds.), pp. 318-341.
-
(1997)
Polyethylene Glycol Chemistry and Biological Applications, ACS Symposium Series 680
, pp. 318-341
-
-
Zalipsky, S.1
Meno-Rudolph, S.2
-
25
-
-
0030059104
-
Site-Specific Attachment of Functionalized Poly(Ethylene glycol) to the Amino Terminus of Proteins
-
Gaertner, H. F., and Offord, R. E. (1996) Site-Specific Attachment of Functionalized Poly(ethylene glycol) to the Amino Terminus of Proteins. Bioconjug. Chem. 7, 38-44.
-
(1996)
Bioconjug. Chem
, vol.7
, pp. 38-44
-
-
Gaertner, H.F.1
Offord, R.E.2
-
26
-
-
0029610548
-
Physical stabilization of insulin by glycosylation
-
Baudys, M., Uchio, T., Mix, D., Wilson, D., and Kim, S. W. (1995) Physical stabilization of insulin by glycosylation. J. Pharm. Sci. 84, 28-33.
-
(1995)
J. Pharm. Sci
, vol.84
, pp. 28-33
-
-
Baudys, M.1
Uchio, T.2
Mix, D.3
Wilson, D.4
Kim, S.W.5
-
27
-
-
0345283166
-
PEGylation of growth hormone-releasing hormone (GRF) analogues
-
Esposito, P., Barbero, L., Caccia, P., Caliceti, P., D’Antonio, M., Piquet, G., Veronese, F. M. (2003) PEGylation of growth hormone-releasing hormone (GRF) analogues. Adv. Drug Del. Rev. 55, 1279-1291
-
(2003)
Adv. Drug Del. Rev
, vol.55
, pp. 1279-1291
-
-
Esposito, P.1
Barbero, L.2
Caccia, P.3
Caliceti, P.4
D’Antonio, M.5
Piquet, G.6
Veronese, F.M.7
-
28
-
-
36849039611
-
Site- Specific PEGylation of G-CSF by Reversible Denaturation
-
Veronese, F. M., Mero, A., Caboi, F., Sergi, M., Marongiu, C., and Pasut, G. (2007) Site- Specific PEGylation of G-CSF by Reversible Denaturation. Bioconjug. Chem. 18, 1824-1830.
-
(2007)
Bioconjug. Chem
, vol.18
, pp. 1824-1830
-
-
Veronese, F.M.1
Mero, A.2
Caboi, F.3
Sergi, M.4
Marongiu, C.5
Pasut, G.6
-
29
-
-
0036860070
-
Selective Alkylation and Acylation of a and e Amino Groups with PEG in a Somatostatin Analogue: Tailored Chemistry for Optimized Bioconjugates
-
Morpurgo, M., Monfardini, C., Hofland, L. J., Sergi, M., Orsolini, P., Dumont, J. M., and Veronese, F. M. (2002) Selective Alkylation and Acylation of a and e Amino Groups with PEG in a Somatostatin Analogue: Tailored Chemistry for Optimized Bioconjugates. Bioconjug. Chem. 13, 1238-1243.
-
(2002)
Bioconjug. Chem
, vol.13
, pp. 1238-1243
-
-
Morpurgo, M.1
Monfardini, C.2
Hofland, L.J.3
Sergi, M.4
Orsolini, P.5
Dumont, J.M.6
Veronese, F.M.7
-
30
-
-
33846874991
-
High-yield production of biologically active mono-PEGylated salmon calcitonin by sitespecific PEGylation
-
Youn, Y. S., Na, D. H., Lee, K. C. (2007) High-yield production of biologically active mono-PEGylated salmon calcitonin by sitespecific PEGylation. J. Control Release 117, 371-379.
-
(2007)
J. Control Release
, vol.117
, pp. 371-379
-
-
Youn, Y.S.1
Na, D.H.2
Lee, K.C.3
-
31
-
-
38949154100
-
Preparation, characterization, and application of biotinylated and biotin-PEGylated glucagon-like peptide-1 analogues for enhanced oral delivery
-
Chae, S. Y. J. C. H., Shin, H. J., Youn, Y. S., Lee, S., Lee, K.C. (2008) Preparation, characterization, and application of biotinylated and biotin-PEGylated glucagon-like peptide-1 analogues for enhanced oral delivery. Bioconjug. Chem. 19, 334-341.
-
(2008)
Bioconjug. Chem.
, vol.19
, pp. 334-341
-
-
Chae, S.1
Shin, H.J.2
Youn, Y.S.3
Lee, S.4
Lee, K.C.5
-
32
-
-
0037124507
-
Enzymatic procedure for sitespecific PEGylation
-
Sato, H. (2002) Enzymatic procedure for sitespecific PEGylation. Adv. Drug Delivery. Rev. 54, 487-504.
-
(2002)
Adv. Drug Delivery. Rev
, vol.54
, pp. 487-504
-
-
Sato, H.1
-
33
-
-
36549039553
-
Site-specific modification and PEGylation of pharmaceutical proteins mediated by transglutaminase
-
Fontana, A., Spolaore, B., Mero, A., and Veronese, F. M. (2008) Site-specific modification and PEGylation of pharmaceutical proteins mediated by transglutaminase. Adv. Drug Delivery Rev. 60, 13-28.
-
(2008)
Adv. Drug Delivery Rev
, vol.60
, pp. 13-28
-
-
Fontana, A.1
Spolaore, B.2
Mero, A.3
Veronese, F.M.4
-
34
-
-
58149494371
-
Quantitation of free polyethylene glycol in PEGylated protein conjugate by size exclusion HPLC with refractive index (RI) detection
-
Li, N., Ziegemeier, D., Bass, L., Wang, W. (2008) Quantitation of free polyethylene glycol in PEGylated protein conjugate by size exclusion HPLC with refractive index (RI) detection. J. Pharm Biomed Anal. 48, 1332-1338.
-
(2008)
J. Pharm Biomed Anal
, vol.48
, pp. 1332-1338
-
-
Li, N.1
Ziegemeier, D.2
Bass, L.3
Wang, W.4
-
35
-
-
0019166514
-
A method for the estimation of polyethylene glycol in plasma protein fractions
-
Sims, G. E., and Snape, T. J. (1980) A method for the estimation of polyethylene glycol in plasma protein fractions. Anal. Biochem. 107, 60-63.
-
(1980)
Anal. Biochem
, vol.107
, pp. 60-63
-
-
Sims, G.E.1
Snape, T.J.2
-
36
-
-
0035951339
-
Use of ionexchange chromatography and hydrophobic interaction chromatography in the preparation and recovery of polyethylene glycol-linked proteins
-
Seely, J. E., Richey, C. W. (2001) Use of ionexchange chromatography and hydrophobic interaction chromatography in the preparation and recovery of polyethylene glycol-linked proteins. J. Chromatogr. A 908, 235-241.
-
(2001)
J. Chromatogr. A
, vol.908
, pp. 235-241
-
-
Seely, J.E.1
Richey, C.W.2
-
37
-
-
15244350788
-
Making site-specific PEGylation work
-
Seely, J. E., Buckel, S. D., Green, P. D., Richey, C. W. (2005) Making site-specific PEGylation work. Biopharm Int. 18, 30-35.
-
(2005)
Biopharm Int
, vol.18
, pp. 30-35
-
-
Seely, J.E.1
Buckel, S.D.2
Green, P.D.3
Richey, C.W.4
-
38
-
-
0034609586
-
Identification of the major positional isomer of pegylated interferon alpha-2b
-
Wang, Y. S., Youngster, S., Bausch, J., Zhang, R., McNemar, C., Wyss, D. F. (2000) Identification of the major positional isomer of pegylated interferon alpha-2b. Biochemistry 39, 10634-10640.
-
(2000)
Biochemistry
, vol.39
, pp. 10634-10640
-
-
Wang, Y.S.1
Youngster, S.2
Bausch, J.3
Zhang, R.4
McNemar, C.5
Wyss, D.F.6
-
39
-
-
27844515221
-
PEGproteins: Reaction engineering and separation issues
-
Fee, C. J., Van Alstine, J. M. (2006) PEGproteins: Reaction engineering and separation issues. Chem. Eng. Sci. 61, 924-939.
-
(2006)
Chem. Eng. Sci
, vol.61
, pp. 924-939
-
-
Fee, C.J.1
Van Alstine, J.M.2
-
40
-
-
33947502313
-
Comparison of strong anion-exchangers for the purification of a PEGylated protein
-
Pabst, T. M., Buckley, J. J., Ramasubramanyan, N., Hunter, A. K. (2007) Comparison of strong anion-exchangers for the purification of a PEGylated protein. J. Chromatogr. A 1147, 172-182.
-
(2007)
J. Chromatogr. A
, vol.1147
, pp. 172-182
-
-
Pabst, T.M.1
Buckley, J.J.2
Ramasubramanyan, N.3
Hunter, A.K.4
-
41
-
-
70349792165
-
Separation of positional isomers of monopoly(Ethylene glycol)-modified octreotides by reversed-phase high-performance liquid chromatography
-
Park, E. J., Lee, K. C, Na, D. H. (2009) Separation of positional isomers of monopoly(ethylene glycol)-modified octreotides by reversed-phase high-performance liquid chromatography. J Chromatogr. A 6, 7793-7797.
-
(2009)
J Chromatogr. A
, vol.6
, pp. 7793-7797
-
-
Park, E.J.1
Lee, K.C.2
Na, D.H.3
-
42
-
-
9544220647
-
Long-acting Growth Hormones Produced by Conjugation with Polyethylene Glycol
-
Clark, R., Olson, K., Fuh, G., Mariani, M., Mortensen, D., Teshima, G., Chang, S., Chu, H., Mukku, V., Canova-Davis, E., Somers, T., Cronin, M., Winkler, M., and Wells, J. A. (1996) Long-acting Growth Hormones Produced by Conjugation with Polyethylene Glycol. J. Biol. Chem. 271, 21969-21977.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 21969-21977
-
-
Clark, R.1
Olson, K.2
Fuh, G.3
Mariani, M.4
Mortensen, D.5
Teshima, G.6
Chang, S.7
Chu, H.8
Mukku, V.9
Canova-Davis, E.10
Somers, T.11
Cronin, M.12
Winkler, M.13
Wells, J.A.14
-
43
-
-
0038010128
-
Isolation, structural characterization, and antiviral activity of positional isomers of monopegylated interferon alpha-2a (PEGASYS)
-
Foser, S., Schacher, A., Weyer, K. A., Brugger, D., et al. (2003) Isolation, structural characterization, and antiviral activity of positional isomers of monopegylated interferon alpha-2a (PEGASYS). Protein Expr. Purif. 30, 78-87.
-
(2003)
Protein Expr. Purif
, vol.30
, pp. 78-87
-
-
Foser, S.1
Schacher, A.2
Weyer, K.A.3
Brugger, D.4
-
44
-
-
39549112760
-
Obstacles and pitfalls in the PEGylation of therapeutic proteins
-
Gaberc-Porekar, V., Zore, I., Podobnik, B., Menart, V. (2008) Obstacles and pitfalls in the PEGylation of therapeutic proteins. Curr. Opin. Drug Discov. Devel. 11, 242-250.
-
(2008)
Curr. Opin. Drug Discov. Devel
, vol.11
, pp. 242-250
-
-
Gaberc-Porekar, V.1
Zore, I.2
Podobnik, B.3
Menart, V.4
-
45
-
-
36549084078
-
Formulation of Neulasta(R) (pegfilgrastim)
-
Piedmonte, D. M., Treuheit, M. J. (2008) Formulation of Neulasta(R) (pegfilgrastim). Adv. Drug Del. Rev. 60, 50-58.
-
(2008)
Adv. Drug Del. Rev
, vol.60
, pp. 50-58
-
-
Piedmonte, D.M.1
Treuheit, M.J.2
-
46
-
-
35648954720
-
Size comparison between proteins PEGylated with branched and linear poly(Ethylene glycol) molecules
-
Fee, C. J (2007) Size comparison between proteins PEGylated with branched and linear poly(ethylene glycol) molecules. Biotechnol Bioeng. 98, 725-731.
-
(2007)
Biotechnol Bioeng
, vol.98
, pp. 725-731
-
-
Fee, C.J.1
-
47
-
-
0344851745
-
Design of PEGylated soluble tumor necrosis factor receptor type I (PEG sTNF-RI) for chronic inflammatory diseases
-
Edwards, C. K., Martin, S. W., Seely, J., Kinstler, O. et al. (2003) Design of PEGylated soluble tumor necrosis factor receptor type I (PEG sTNF-RI) for chronic inflammatory diseases. Adv. Drug Deliv. Rev. 55, 1315-1336.
-
(2003)
Adv. Drug Deliv. Rev
, vol.55
, pp. 1315-1336
-
-
Edwards, C.K.1
Martin, S.W.2
Seely, J.3
Kinstler, O.4
-
48
-
-
33749369528
-
Ultrafiltration characteristics of pegylated proteins
-
Molek, J. R., Zydney, A. L. (2006) Ultrafiltration characteristics of pegylated proteins. Biotechnol. Bioeng. 95, 474-482.
-
(2006)
Biotechnol. Bioeng
, vol.95
, pp. 474-482
-
-
Molek, J.R.1
Zydney, A.L.2
-
49
-
-
44249102502
-
Ultrafiltration of PEGylated proteins: Fouling and concentration polarization effects
-
Kwon, B., Molek, J., Zydney, A. L. (2008) Ultrafiltration of PEGylated proteins: Fouling and concentration polarization effects. J. Memb. Sci. 319, 206-213.
-
(2008)
J. Memb. Sci
, vol.319
, pp. 206-213
-
-
Kwon, B.1
Molek, J.2
Zydney, A.L.3
-
50
-
-
0013889689
-
Determination of free amino groups in protein by trinitrobenzenesulphonic acid
-
Habeeb, A. F. S. A. (1966) Determination of free amino groups in protein by trinitrobenzenesulphonic acid. Anal.Biochem. 14, 328-336.
-
(1966)
Anal.Biochem.
, vol.14
, pp. 328-336
-
-
Habeeb, A.F.S.A.1
-
51
-
-
0020695584
-
Reassessment of Ellman’s reagent
-
Riddles, P. W., Blakeley, R. L., and Zarner, B. (1983) Reassessment of Ellman’s reagent. Methods Enzymol. 91, 49-60.
-
(1983)
Methods Enzymol
, vol.91
, pp. 49-60
-
-
Riddles, P.W.1
Blakeley, R.L.2
Zarner, B.3
-
52
-
-
28244489661
-
Methods for Structural Analysis of Protein Pharmaceuticals Biotechnology: Pharmaceutical Aspects
-
Springer, New York
-
Jiskoot, W., Crommelin, D. (2005) Methods for Structural Analysis of Protein Pharmaceuticals Biotechnology: Pharmaceutical Aspects. American Assoc. of Pharm. Scientists, Springer, New York.
-
(2005)
American Assoc of Pharm. Scientists
-
-
Jiskoot, W.1
Crommelin, D.2
-
53
-
-
85020918018
-
-
www.piercenet.com
-
-
-
-
54
-
-
54349121309
-
Size of Pegylated Protein Conjugates Studied by Various Methods
-
Kusterle, M., Jevsevar, S., Gaberc-Porekar, V. (2008) Size of Pegylated Protein Conjugates Studied by Various Methods. Acta Chim. Slov. 55, 594-601.
-
(2008)
Acta Chim. Slov
, vol.55
, pp. 594-601
-
-
Kusterle, M.1
Jevsevar, S.2
Gaberc-Porekar, V.3
-
55
-
-
36549084078
-
Formulation of Neulasta(R) (pegfilgrastim)
-
Piedmonte, D. M., Treuheit, M. J. (2008) Formulation of Neulasta(R) (pegfilgrastim). Adv. Drug Del. Rev. 60, 50-58.
-
(2008)
Adv. Drug Del. Rev
, vol.60
, pp. 50-58
-
-
Piedmonte, D.M.1
Treuheit, M.J.2
-
56
-
-
0033055121
-
Isolation, characterizasion, and stability of positional isomers of mono-PEGylated salmon calcitonins
-
Lee, K., Moon, S. C., Park, M. O., Lee, J. T., Na, D. H., Yoo, S. D., et al. (1999) Isolation, characterizasion, and stability of positional isomers of mono-PEGylated salmon calcitonins. Pharm. Res. 16, 813-818.
-
(1999)
Pharm. Res
, vol.16
, pp. 813-818
-
-
Lee, K.1
Moon, S.C.2
Park, M.O.3
Lee, J.T.4
Na, D.H.5
Yoo, S.D.6
-
57
-
-
0037343959
-
Site-Specific PEGylation of Hemoglobin at Cys-93(B): Correlation between the Colligative Properties of the PEGylated Protein and the Length of the Conjugated PEG Chain
-
Manjula, B. N., Tsai, A., Upadhya, R., Perumalsamy, K., Smith, P. K., Malavalli, A., Vandegriff, K. R., Winslow, M., Intaglietta, M., Prabhakaran, M., Friedman, J. M., and Acharya A. S. (2003) Site-Specific PEGylation of Hemoglobin at Cys-93(b): Correlation between the Colligative Properties of the PEGylated Protein and the Length of the Conjugated PEG Chain. Bioconjug. Chem. 14, 464-472.
-
(2003)
Bioconjug. Chem
, vol.14
, pp. 464-472
-
-
Manjula, B.N.1
Tsai, A.2
Upadhya, R.3
Perumalsamy, K.4
Smith, P.K.5
Malavalli, A.6
Vandegriff, K.R.7
Winslow, M.8
Intaglietta, M.9
Prabhakaran, M.10
Friedman, J.M.11
Acharya, A.S.12
-
58
-
-
9244221679
-
Prediction of the viscosity radius and the size exclusion chromatography behavior of PEGylated proteins
-
Fee, C. J., Van Alstine, J. M. (2004) Prediction of the viscosity radius and the size exclusion chromatography behavior of PEGylated proteins. Bioconjug. Chem. 15, 1304-1313.
-
(2004)
Bioconjug. Chem
, vol.15
, pp. 1304-1313
-
-
Fee, C.J.1
Van Alstine, J.M.2
-
59
-
-
0026536995
-
Detection and Molecular-Weight Determination of Polyethylene Glycol-Modified Hirudin by Staining After Sodium Dodecyl-Sulfate Polyacrylamide-Gel Electrophoresis
-
Kurfurst, M. M. (1992) Detection and Molecular-Weight Determination of Polyethylene Glycol-Modified Hirudin by Staining After Sodium Dodecyl-Sulfate Polyacrylamide-Gel Electrophoresis. Anal. Biochem. 200, 244-248.
-
(1992)
Anal. Biochem
, vol.200
, pp. 244-248
-
-
Kurfurst, M.M.1
-
60
-
-
67650651196
-
PEGylation Promotes Hemoglobin Tetramer Dissociation
-
Caccia, D., Ronda, L., Frassi, R., Perrella, M., Del Bavero, E., Bruno, S., Pioselli, B., Abbruzzetti, S., Viappiani, C., and Mozzarelli A. (2009) PEGylation Promotes Hemoglobin Tetramer Dissociation. Bioconjug. Chem. 20, 1356-1366.
-
(2009)
Bioconjug. Chem
, vol.20
, pp. 1356-1366
-
-
Caccia, D.1
Ronda, L.2
Frassi, R.3
Perrella, M.4
Del Bavero, E.5
Bruno, S.6
Pioselli, B.7
Abbruzzetti, S.8
Viappiani, C.9
Mozzarelli, A.10
-
61
-
-
65049088090
-
Correlations between in vitro potency of polyethylene glycol-protein conjugates and their chromatographic behaviour
-
Caserman, S., Kusterle, M., Kunstelj, M., Milunovic, T. et al. (2009) Correlations between in vitro potency of polyethylene glycol-protein conjugates and their chromatographic behaviour. Anal. Biochem. 389, 27-31.
-
(2009)
Anal. Biochem
, vol.389
, pp. 27-31
-
-
Caserman, S.1
Kusterle, M.2
Kunstelj, M.3
Milunovic, T.4
-
62
-
-
34250006003
-
Structural characterization of PEGylated rHuG-CSF and location of PEG attachment sites
-
Cindric, M., Cepo, T., Galic, N., Bukvic-Krajacic, M. et al. (2007) Structural characterization of PEGylated rHuG-CSF and location of PEG attachment sites. J. Pharm. Biomed. Anal. 44, 388-395.
-
(2007)
J. Pharm. Biomed. Anal
, vol.44
, pp. 388-395
-
-
Cindric, M.1
Cepo, T.2
Galic, N.3
Bukvic-Krajacic, M.4
-
63
-
-
62549119508
-
Transglutaminase-Mediated PEGylation of Proteins: Direct Identification by Mass Spectrometry Using a Novel Monodisperse PEG
-
Mero, A., Spolaore, B., Veronese, F. M., and Fontana, A. (2009) Transglutaminase-Mediated PEGylation of Proteins: Direct Identification by Mass Spectrometry Using a Novel Monodisperse PEG. Bioconjug. Chem. 20, 384-389.
-
(2009)
Bioconjug. Chem
, vol.20
, pp. 384-389
-
-
Mero, A.1
Spolaore, B.2
Veronese, F.M.3
Fontana, A.4
-
64
-
-
84859231562
-
Enzymatic techniques for PEGylation of biopharmaceuticals
-
(Veronese, F.M., ed.) Birkhauser Verlag, Boston, MA
-
Sergi, M., Caboi, F., Maullu, C., Orsini, G., and Tonon, G. (2009) Enzymatic techniques for PEGylation of biopharmaceuticals. In PEGylated Protein Drugs: Basic Science and Clinical Applications (Milestones in Drug Therapy) (Veronese, F.M., ed.) Birkhauser Verlag, Boston, MA, pp. 75-88.
-
(2009)
Pegylated Protein Drugs: Basic Science and Clinical Applications (Milestones in Drug Therapy)
, pp. 75-88
-
-
Sergi, M.1
Caboi, F.2
Maullu, C.3
Orsini, G.4
Tonon, G.5
-
65
-
-
33646909899
-
Structure-function engineering of interferon-beta-1b for improving stability, solubility, potency, immunogenicity, and pharmacokinetic properties by site-selective mono-PEGylation
-
Basu, A., Yang, K., Wang, M., Liu, S., et al. (2006) Structure-function engineering of interferon-beta-1b for improving stability, solubility, potency, immunogenicity, and pharmacokinetic properties by site-selective mono-PEGylation. Bioconjug. Chem. 17, 618-30.
-
(2006)
Bioconjug. Chem
, vol.17
, pp. 618-630
-
-
Basu, A.1
Yang, K.2
Wang, M.3
Liu, S.4
-
66
-
-
0025211779
-
Quantification of protein
-
Stoscheck, C. M. (1990) Quantification of protein. Methods Enzymol. 182, 50-69.
-
(1990)
Methods Enzymol
, vol.182
, pp. 50-69
-
-
Stoscheck, C.M.1
-
67
-
-
34250752396
-
Investigation on PEGylation strategy of recombinant human interleukin-1 receptor antagonist
-
Yu, P., Zheng, C., Chen, J., Zhang, et al. (2007) Investigation on PEGylation strategy of recombinant human interleukin-1 receptor antagonist. Bioorg. Med. Chem. 15, 5396-405.
-
(2007)
Bioorg. Med. Chem
, vol.15
, pp. 5396-5405
-
-
Yu, P.1
Zheng, C.2
Chen, Zhang, J.3
-
68
-
-
0029167706
-
A branched monomethoxypoly (Ethylen glicol) for protein modification
-
Monfardini, C., Schiavon, O., Caliceti, P., Morpurgo, M., Harris, J. M., and Veronese, F. M. (1995) A branched monomethoxypoly (ethylen glicol) for protein modification. Bioconjug. Chem. 6, 62-69.
-
(1995)
Bioconjug. Chem
, vol.6
, pp. 62-69
-
-
Monfardini, C.1
Schiavon, O.2
Caliceti, P.3
Morpurgo, M.4
Harris, J.M.5
Veronese, F.M.6
-
69
-
-
0035086519
-
Rational design of a potent, long-lasting form of interferon: A 40 kDa branched polyethylene glycol-conjugated interferon alpha-2a for the treatment of hepatitis C
-
Bailon, P., Palleroni, A., Schaffer, C. A., Spence, C. L. et al. (2001) Rational design of a potent, long-lasting form of interferon: A 40 kDa branched polyethylene glycol-conjugated interferon alpha-2a for the treatment of hepatitis C. Bioconjug. Chem. 12, 195-202.
-
(2001)
Bioconjug. Chem
, vol.12
, pp. 195-202
-
-
Bailon, P.1
Palleroni, A.2
Schaffer, C.A.3
Spence, C.L.4
|