PEGylation promotes hemoglobin tetramer dissociation

Bioconjugate Chemistry

Volumn 20, Issue 7, 2009, Pages 1356-1366

  Caccia, Dario ^a   Ronda, Luca ^a,b   Frassi, Raffaella ^a   Perrella, Michele ^a   Del Favero, Elena ^a   Bruno, Stefano ^b   Pioselli, Barbara ^b   Abbruzzetti, Stefania ^b   Viappiani, Cristiano ^b   Mozzarelli, Andrea ^b,c  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF PARMA   (Italy)

^c CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; DIMERS; DISSOCIATION; OXYGEN; PHOTOLYSIS; PHYSIOLOGICAL MODELS; POLYETHYLENE GLYCOLS; SIZE EXCLUSION CHROMATOGRAPHY;

ADVERSE EFFECT; DELIVERY CONTROL; HAEMOGLOBINS; HEMOGLOBIN TETRAMER; OXYGEN CARRIER; OXYGEN DELIVERY; PEGYLATED; PEGYLATED HEMOGLOBINS; PEGYLATION; RED BLOOD CELL;

HEMOGLOBIN;

ARTIFICIAL BLOOD; BLOOD SUBSTITUTE; CARBON MONOXIDE; CARBOXYHEMOGLOBIN; HEMOGLOBIN A; HEMOGLOBIN DERIVATIVE; HEMOSPAN; MACROGOL; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; BINDING KINETICS; CONCENTRATION RESPONSE; DISSOCIATION CONSTANT; DRUG CONJUGATION; HYDRODYNAMICS; MOLECULAR WEIGHT; PROTEIN MODIFICATION; PROTEIN QUATERNARY STRUCTURE;

EID: 67650651196     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc900130f     Document Type: Article

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