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Volumn 64, Issue 14, 1999, Pages 1163-1175

Site-directed polyethylene glycol modification of trichosanthin: Effects on its biological activities, pharmacokinetics, and antigenicity

(4) He, Xian Hui a Shaw, Pang Chui a Xu, Li Hui a Tam, Siu Cheung b

a CHINESE UNIVERSITY OF HONG KONG (Hong Kong)

b and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics (Hong Kong)

Author keywords

PEGylation; Pharmacokinetics; Ribosome inactivating protein; Site directed mutagenesis; Trichosanthin

Indexed keywords

ABORTIVE AGENT; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; MACROGOL; MONOCLONAL ANTIBODY; RIBOSOME INACTIVATING PROTEIN; TRICHOSANTHIN;

ANTIGENICITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CHROMATOGRAPHY; COMPUTER MODEL; CYTOTOXICITY; DRUG HALF LIFE; DRUG POTENCY; ENZYME LINKED IMMUNOSORBENT ASSAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNE RESPONSE; IMMUNOGENICITY; SITE DIRECTED MUTAGENESIS; STATISTICAL ANALYSIS;

EID: 0033605042 PISSN: 00243205 EISSN: None Source Type: Journal
DOI: 10.1016/S0024-3205(99)00048-X Document Type: Article

Times cited : (34)

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