-
1
-
-
0037020329
-
Drug design strategies for targeting G-protein-coupled receptors
-
10.1002/1439-7633(20021004)3:10<928::AID-CBIC928>3.0.CO;2-5, 12362358
-
Klabunde T, Hessler G. Drug design strategies for targeting G-protein-coupled receptors. ChemBioChem 2002, 3(10):928-944. 10.1002/1439-7633(20021004)3:10<928::AID-CBIC928>3.0.CO;2-5, 12362358.
-
(2002)
ChemBioChem
, vol.3
, Issue.10
, pp. 928-944
-
-
Klabunde, T.1
Hessler, G.2
-
2
-
-
0036717194
-
The druggable genome
-
10.1038/nrd892, 12209152
-
Hopkins AL, Groom CR. The druggable genome. Nat Rev Drug Discov 2002, 1(9):727-730. 10.1038/nrd892, 12209152.
-
(2002)
Nat Rev Drug Discov
, vol.1
, Issue.9
, pp. 727-730
-
-
Hopkins, A.L.1
Groom, C.R.2
-
3
-
-
0028174033
-
Fingerprinting G-protein-coupled receptors
-
10.1093/protein/7.2.195, 8170923
-
Attwood TK, Findlay JB. Fingerprinting G-protein-coupled receptors. Protein Eng 1994, 7(2):195-203. 10.1093/protein/7.2.195, 8170923.
-
(1994)
Protein Eng
, vol.7
, Issue.2
, pp. 195-203
-
-
Attwood, T.K.1
Findlay, J.B.2
-
4
-
-
0028338534
-
GCRDb: a G-protein-coupled receptor database
-
Kolakowski LF. GCRDb: a G-protein-coupled receptor database. Receptors Channels 1994, 2(1):1-7.
-
(1994)
Receptors Channels
, vol.2
, Issue.1
, pp. 1-7
-
-
Kolakowski, L.F.1
-
5
-
-
0037252680
-
GPCRDB information system for G protein-coupled receptors
-
10.1093/nar/gkg103, 165550, 12520006
-
Horn F, Bettler E, Oliveira L, Campagne F, Cohen FE, Vriend G. GPCRDB information system for G protein-coupled receptors. Nucleic Acids Res 2003, 31(1):294-297. 10.1093/nar/gkg103, 165550, 12520006.
-
(2003)
Nucleic Acids Res
, vol.31
, Issue.1
, pp. 294-297
-
-
Horn, F.1
Bettler, E.2
Oliveira, L.3
Campagne, F.4
Cohen, F.E.5
Vriend, G.6
-
6
-
-
33748671369
-
The 7 TM G-protein-coupled receptor target family
-
Jacoby E, Bouhelal R, Gerspacher M, Seuwen K. The 7 TM G-protein-coupled receptor target family. ChemMedChem 2006, 1(8):761-782.
-
(2006)
ChemMedChem
, vol.1
, Issue.8
, pp. 761-782
-
-
Jacoby, E.1
Bouhelal, R.2
Gerspacher, M.3
Seuwen, K.4
-
7
-
-
22944457221
-
International Union of Pharmacology. XLVI. G protein-coupled receptor list
-
10.1124/pr.57.2.5, 15914470
-
Foord SM, Bonner TI, Neubig RR, Rosser EM, Pin JP, Davenport AP, Spedding M, Harmar AJ. International Union of Pharmacology. XLVI. G protein-coupled receptor list. Pharmacol Rev 2005, 57(2):279-288. 10.1124/pr.57.2.5, 15914470.
-
(2005)
Pharmacol Rev
, vol.57
, Issue.2
, pp. 279-288
-
-
Foord, S.M.1
Bonner, T.I.2
Neubig, R.R.3
Rosser, E.M.4
Pin, J.P.5
Davenport, A.P.6
Spedding, M.7
Harmar, A.J.8
-
8
-
-
0036463901
-
Efficacy at G-protein-coupled receptors
-
10.1038/nrd722, 12120091
-
Kenakin T. Efficacy at G-protein-coupled receptors. Nat Rev Drug Discov 2002, 1(2):103-110. 10.1038/nrd722, 12120091.
-
(2002)
Nat Rev Drug Discov
, vol.1
, Issue.2
, pp. 103-110
-
-
Kenakin, T.1
-
9
-
-
0036490942
-
Allosteric binding sites on cell-surface receptors: novel targets for drug discovery
-
10.1038/nrd746, 12120504
-
Christopoulos A. Allosteric binding sites on cell-surface receptors: novel targets for drug discovery. Nat Rev Drug Discov 2002, 1(3):198-210. 10.1038/nrd746, 12120504.
-
(2002)
Nat Rev Drug Discov
, vol.1
, Issue.3
, pp. 198-210
-
-
Christopoulos, A.1
-
10
-
-
22944487986
-
Multiple signaling states of G-protein-coupled receptors
-
10.1124/pr.57.2.2, 15914464
-
Perez DM, Karnik SS. Multiple signaling states of G-protein-coupled receptors. Pharmacol Rev 2005, 57(2):147-161. 10.1124/pr.57.2.2, 15914464.
-
(2005)
Pharmacol Rev
, vol.57
, Issue.2
, pp. 147-161
-
-
Perez, D.M.1
Karnik, S.S.2
-
11
-
-
22944452140
-
The origins of diversity and specificity in g protein-coupled receptor signaling
-
10.1124/jpet.105.083121, 2656918, 15805429
-
Maudsley S, Martin B, Luttrell LM. The origins of diversity and specificity in g protein-coupled receptor signaling. J Pharmacol Exp Ther 2005, 314(2):485-494. 10.1124/jpet.105.083121, 2656918, 15805429.
-
(2005)
J Pharmacol Exp Ther
, vol.314
, Issue.2
, pp. 485-494
-
-
Maudsley, S.1
Martin, B.2
Luttrell, L.M.3
-
12
-
-
33845903110
-
Functional selectivity and classical concepts of quantitative pharmacology
-
Urban JD, Clarke WP, von Zastrow M, Nichols DE, Kobilka B, Weinstein H, Javitch JA, Roth BL, Christopoulos A, Sexton PM, et al. Functional selectivity and classical concepts of quantitative pharmacology. J Pharmacol Exp Ther 2007, 320(1):1-13.
-
(2007)
J Pharmacol Exp Ther
, vol.320
, Issue.1
, pp. 1-13
-
-
Urban, J.D.1
Clarke, W.P.2
von Zastrow, M.3
Nichols, D.E.4
Kobilka, B.5
Weinstein, H.6
Javitch, J.A.7
Roth, B.L.8
Christopoulos, A.9
Sexton, P.M.10
-
13
-
-
0035336676
-
Activation of rhodopsin: new insights from structural and biochemical studies
-
10.1016/S0968-0004(01)01799-6, 11343925
-
Okada T, Ernst OP, Palczewski K, Hofmann KP. Activation of rhodopsin: new insights from structural and biochemical studies. Trends Biochem Sci 2001, 26(5):318-324. 10.1016/S0968-0004(01)01799-6, 11343925.
-
(2001)
Trends Biochem Sci
, vol.26
, Issue.5
, pp. 318-324
-
-
Okada, T.1
Ernst, O.P.2
Palczewski, K.3
Hofmann, K.P.4
-
14
-
-
0028845598
-
An evolutionary view of drug-receptor interaction: the bioamine receptor family
-
10.1016/S0165-6147(00)89078-1, 8578606
-
Vernier P, Cardinaud B, Valdenaire O, Philippe H, Vincent JD. An evolutionary view of drug-receptor interaction: the bioamine receptor family. Trends Pharmacol Sci 1995, 16(11):375-381. 10.1016/S0165-6147(00)89078-1, 8578606.
-
(1995)
Trends Pharmacol Sci
, vol.16
, Issue.11
, pp. 375-381
-
-
Vernier, P.1
Cardinaud, B.2
Valdenaire, O.3
Philippe, H.4
Vincent, J.D.5
-
15
-
-
0035209620
-
International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors
-
Fredholm BB, AP IJ, Jacobson KA, Klotz KN, Linden J. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev 2001, 53(4):527-552.
-
(2001)
Pharmacol Rev
, vol.53
, Issue.4
, pp. 527-552
-
-
Fredholm, B.B.1
AP, I.J.2
Jacobson, K.A.3
Klotz, K.N.4
Linden, J.5
-
17
-
-
0034849509
-
Chemokine receptors
-
10.1016/S1359-6101(01)00014-4, 11544102
-
Horuk R. Chemokine receptors. Cytokine Growth Factor Rev 2001, 12(4):313-335. 10.1016/S1359-6101(01)00014-4, 11544102.
-
(2001)
Cytokine Growth Factor Rev
, vol.12
, Issue.4
, pp. 313-335
-
-
Horuk, R.1
-
18
-
-
11844275233
-
A family of fatty acid binding receptors
-
10.1089/dna.2005.24.54, 15684720
-
Brown AJ, Jupe S, Briscoe CP. A family of fatty acid binding receptors. DNA Cell Biol 2005, 24(1):54-61. 10.1089/dna.2005.24.54, 15684720.
-
(2005)
DNA Cell Biol
, vol.24
, Issue.1
, pp. 54-61
-
-
Brown, A.J.1
Jupe, S.2
Briscoe, C.P.3
-
19
-
-
0036266101
-
International Union of Pharmacology. XXXIV. Lysophospholipid receptor nomenclature
-
10.1124/pr.54.2.265, 12037142
-
Chun J, Goetzl EJ, Hla T, Igarashi Y, Lynch KR, Moolenaar W, Pyne S, Tigyi G. International Union of Pharmacology. XXXIV. Lysophospholipid receptor nomenclature. Pharmacol Rev 2002, 54(2):265-269. 10.1124/pr.54.2.265, 12037142.
-
(2002)
Pharmacol Rev
, vol.54
, Issue.2
, pp. 265-269
-
-
Chun, J.1
Goetzl, E.J.2
Hla, T.3
Igarashi, Y.4
Lynch, K.R.5
Moolenaar, W.6
Pyne, S.7
Tigyi, G.8
-
20
-
-
1542347126
-
International Union of Pharmacology XLIV. Nomenclature for the oxoeicosanoid receptor
-
10.1124/pr.56.1.4, 15001665
-
Brink C, Dahlen SE, Drazen J, Evans JF, Hay DW, Rovati GE, Serhan CN, Shimizu T, Yokomizo T. International Union of Pharmacology XLIV. Nomenclature for the oxoeicosanoid receptor. Pharmacol Rev 2004, 56(1):149-157. 10.1124/pr.56.1.4, 15001665.
-
(2004)
Pharmacol Rev
, vol.56
, Issue.1
, pp. 149-157
-
-
Brink, C.1
Dahlen, S.E.2
Drazen, J.3
Evans, J.F.4
Hay, D.W.5
Rovati, G.E.6
Serhan, C.N.7
Shimizu, T.8
Yokomizo, T.9
-
21
-
-
3042856569
-
A glance at G-protein-coupled receptors for lipid mediators: a growing receptor family with remarkably diverse ligands
-
10.1016/j.pharmthera.2004.04.005, 15246248
-
Kostenis E. A glance at G-protein-coupled receptors for lipid mediators: a growing receptor family with remarkably diverse ligands. Pharmacol Ther 2004, 102(3):243-257. 10.1016/j.pharmthera.2004.04.005, 15246248.
-
(2004)
Pharmacol Ther
, vol.102
, Issue.3
, pp. 243-257
-
-
Kostenis, E.1
-
22
-
-
34548319109
-
Chemogenomic approaches to drug discovery: similar receptors bind similar ligands
-
10.1038/sj.bjp.0707308, 1978276, 17533415
-
Klabunde T. Chemogenomic approaches to drug discovery: similar receptors bind similar ligands. Br J Pharmacol 2007, 152(1):5-7. 10.1038/sj.bjp.0707308, 1978276, 17533415.
-
(2007)
Br J Pharmacol
, vol.152
, Issue.1
, pp. 5-7
-
-
Klabunde, T.1
-
23
-
-
54249130252
-
A signaling-selective, nanomolar potent allosteric low molecular weight agonist for the human luteinizing hormone receptor
-
10.1007/s00210-008-0318-3, 18551279
-
van Koppen CJ, Zaman GJ, Timmers CM, Kelder J, Mosselman S, van de Lagemaat R, Smit MJ, Hanssen RG. A signaling-selective, nanomolar potent allosteric low molecular weight agonist for the human luteinizing hormone receptor. Naunyn Schmiedebergs Arch Pharmacol 2008, 378(5):503-514. 10.1007/s00210-008-0318-3, 18551279.
-
(2008)
Naunyn Schmiedebergs Arch Pharmacol
, vol.378
, Issue.5
, pp. 503-514
-
-
van Koppen, C.J.1
Zaman, G.J.2
Timmers, C.M.3
Kelder, J.4
Mosselman, S.5
van de Lagemaat, R.6
Smit, M.J.7
Hanssen, R.G.8
-
24
-
-
0028844298
-
The binding site of neuropeptide vasopressin V1a receptor. Evidence for a major localization within transmembrane regions
-
10.1074/jbc.270.43.25771, 7592759
-
Mouillac B, Chini B, Balestre MN, Elands J, Trumpp-Kallmeyer S, Hoflack J, Hibert M, Jard S, Barberis C. The binding site of neuropeptide vasopressin V1a receptor. Evidence for a major localization within transmembrane regions. J Biol Chem 1995, 270(43):25771-25777. 10.1074/jbc.270.43.25771, 7592759.
-
(1995)
J Biol Chem
, vol.270
, Issue.43
, pp. 25771-25777
-
-
Mouillac, B.1
Chini, B.2
Balestre, M.N.3
Elands, J.4
Trumpp-Kallmeyer, S.5
Hoflack, J.6
Hibert, M.7
Jard, S.8
Barberis, C.9
-
25
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
10.1126/science.289.5480.739, 10926528
-
Palczewski K, Kumasaka T, Hori T, Behnke CA, Motoshima H, Fox BA, Le Trong I, Teller DC, Okada T, Stenkamp RE, et al. Crystal structure of rhodopsin: A G protein-coupled receptor. Science 2000, 289(5480):739-745. 10.1126/science.289.5480.739, 10926528.
-
(2000)
Science
, vol.289
, Issue.5480
, pp. 739-745
-
-
Palczewski, K.1
Kumasaka, T.2
Hori, T.3
Behnke, C.A.4
Motoshima, H.5
Fox, B.A.6
Le Trong, I.7
Teller, D.C.8
Okada, T.9
Stenkamp, R.E.10
-
26
-
-
43749109187
-
Crystal structure of squid rhodopsin
-
10.1038/nature06925, 18480818
-
Murakami M, Kouyama T. Crystal structure of squid rhodopsin. Nature 2008, 453(7193):363-367. 10.1038/nature06925, 18480818.
-
(2008)
Nature
, vol.453
, Issue.7193
, pp. 363-367
-
-
Murakami, M.1
Kouyama, T.2
-
27
-
-
36448995359
-
High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor
-
10.1126/science.1150577, 2583103, 17962520
-
Cherezov V, Rosenbaum DM, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Kuhn P, Weis WI, Kobilka BK, et al. High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. Science 2007, 318(5854):1258-1265. 10.1126/science.1150577, 2583103, 17962520.
-
(2007)
Science
, vol.318
, Issue.5854
, pp. 1258-1265
-
-
Cherezov, V.1
Rosenbaum, D.M.2
Hanson, M.A.3
Rasmussen, S.G.4
Thian, F.S.5
Kobilka, T.S.6
Choi, H.J.7
Kuhn, P.8
Weis, W.I.9
Kobilka, B.K.10
-
28
-
-
47949129742
-
Structure of a beta1-adrenergic G-protein-coupled receptor
-
10.1038/nature07101, 2923055, 18594507
-
Warne T, Serrano-Vega MJ, Baker JG, Moukhametzianov R, Edwards PC, Henderson R, Leslie AG, Tate CG, Schertler GF. Structure of a beta1-adrenergic G-protein-coupled receptor. Nature 2008, 454(7203):486-491. 10.1038/nature07101, 2923055, 18594507.
-
(2008)
Nature
, vol.454
, Issue.7203
, pp. 486-491
-
-
Warne, T.1
Serrano-Vega, M.J.2
Baker, J.G.3
Moukhametzianov, R.4
Edwards, P.C.5
Henderson, R.6
Leslie, A.G.7
Tate, C.G.8
Schertler, G.F.9
-
29
-
-
56749103466
-
The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist
-
10.1126/science.1164772, 2586971, 18832607
-
Jaakola VP, Griffith MT, Hanson MA, Cherezov V, Chien EY, Lane JR, Ijzerman AP, Stevens RC. The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist. Science 2008, 322(5905):1211-1217. 10.1126/science.1164772, 2586971, 18832607.
-
(2008)
Science
, vol.322
, Issue.5905
, pp. 1211-1217
-
-
Jaakola, V.P.1
Griffith, M.T.2
Hanson, M.A.3
Cherezov, V.4
Chien, E.Y.5
Lane, J.R.6
Ijzerman, A.P.7
Stevens, R.C.8
-
30
-
-
67649518035
-
Homology modeling in drug discovery: current trends and applications
-
676-683
-
Cavasotto CN, Phatak SS. Homology modeling in drug discovery: current trends and applications. Drug Discov Today 2009, 14:(13-14):676-683.
-
(2009)
Drug Discov Today
, vol.14
, pp. 13-14
-
-
Cavasotto, C.N.1
Phatak, S.S.2
-
31
-
-
58149185123
-
Ensembl 2009
-
Database
-
Hubbard TJ, Aken BL, Ayling S, Ballester B, Beal K, Bragin E, Brent S, Chen Y, Clapham P, Clarke L, et al. Ensembl 2009. Nucleic Acids Res 2009, (37 Database):D690-697.
-
(2009)
Nucleic Acids Res
, Issue.37
-
-
Hubbard, T.J.1
Aken, B.L.2
Ayling, S.3
Ballester, B.4
Beal, K.5
Bragin, E.6
Brent, S.7
Chen, Y.8
Clapham, P.9
Clarke, L.10
-
32
-
-
1542379652
-
Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions
-
14660595
-
Madabushi S, Gross AK, Philippi A, Meng EC, Wensel TG, Lichtarge O. Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions. J Biol Chem 2004, 279(14660595):8126-8132.
-
(2004)
J Biol Chem
, vol.279
, pp. 8126-8132
-
-
Madabushi, S.1
Gross, A.K.2
Philippi, A.3
Meng, E.C.4
Wensel, T.G.5
Lichtarge, O.6
-
33
-
-
0042921467
-
Sequence analysis reveals how G protein-coupled receptors transduce the signal to the G protein
-
10.1002/prot.10489, 12910455
-
Oliveira L, Paiva PB, Paiva AC, Vriend G. Sequence analysis reveals how G protein-coupled receptors transduce the signal to the G protein. Proteins 2003, 52(4):553-560. 10.1002/prot.10489, 12910455.
-
(2003)
Proteins
, vol.52
, Issue.4
, pp. 553-560
-
-
Oliveira, L.1
Paiva, P.B.2
Paiva, A.C.3
Vriend, G.4
-
34
-
-
33646813254
-
A two-entropies analysis to identify functional positions in the transmembrane region of class A G protein-coupled receptors
-
10.1002/prot.20899, 16532452
-
Ye K, Lameijer EW, Beukers MW, Ijzerman AP. A two-entropies analysis to identify functional positions in the transmembrane region of class A G protein-coupled receptors. Proteins 2006, 63(4):1018-1030. 10.1002/prot.20899, 16532452.
-
(2006)
Proteins
, vol.63
, Issue.4
, pp. 1018-1030
-
-
Ye, K.1
Lameijer, E.W.2
Beukers, M.W.3
Ijzerman, A.P.4
-
35
-
-
33747754105
-
Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse
-
10.1016/j.ygeno.2006.04.001, 16753280
-
Bjarnadottir TK, Gloriam DE, Hellstrand SH, Kristiansson H, Fredriksson R, Schioth HB. Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse. Genomics 2006, 88(3):263-273. 10.1016/j.ygeno.2006.04.001, 16753280.
-
(2006)
Genomics
, vol.88
, Issue.3
, pp. 263-273
-
-
Bjarnadottir, T.K.1
Gloriam, D.E.2
Hellstrand, S.H.3
Kristiansson, H.4
Fredriksson, R.5
Schioth, H.B.6
-
36
-
-
58149183694
-
IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels
-
Database
-
Harmar AJ, Hills RA, Rosser EM, Jones M, Buneman OP, Dunbar DR, Greenhill SD, Hale VA, Sharman JL, Bonner TI, et al. IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels. Nucleic Acids Res 2009, (37 Database):D680-685.
-
(2009)
Nucleic Acids Res
, Issue.37
-
-
Harmar, A.J.1
Hills, R.A.2
Rosser, E.M.3
Jones, M.4
Buneman, O.P.5
Dunbar, D.R.6
Greenhill, S.D.7
Hale, V.A.8
Sharman, J.L.9
Bonner, T.I.10
-
37
-
-
37549049756
-
Multi-RELIEF: a method to recognize specificity determining residues from multiple sequence alignments using a Machine-Learning approach for feature weighting
-
10.1093/bioinformatics/btm537, 18024975
-
Ye K, Feenstra KA, Heringa J, Ijzerman AP, Marchiori E. Multi-RELIEF: a method to recognize specificity determining residues from multiple sequence alignments using a Machine-Learning approach for feature weighting. Bioinformatics 2008, 24(1):18-25. 10.1093/bioinformatics/btm537, 18024975.
-
(2008)
Bioinformatics
, vol.24
, Issue.1
, pp. 18-25
-
-
Ye, K.1
Feenstra, K.A.2
Heringa, J.3
Ijzerman, A.P.4
Marchiori, E.5
-
38
-
-
0242362595
-
Modeling the adenosine receptors: comparison of the binding domains of A2A agonists and antagonists
-
10.1021/jm0300431, 14584936
-
Kim SK, Gao ZG, Van Rompaey P, Gross AS, Chen A, Van Calenbergh S, Jacobson KA. Modeling the adenosine receptors: comparison of the binding domains of A2A agonists and antagonists. J Med Chem 2003, 46(23):4847-4859. 10.1021/jm0300431, 14584936.
-
(2003)
J Med Chem
, vol.46
, Issue.23
, pp. 4847-4859
-
-
Kim, S.K.1
Gao, Z.G.2
Van Rompaey, P.3
Gross, A.S.4
Chen, A.5
Van Calenbergh, S.6
Jacobson, K.A.7
-
39
-
-
0027371827
-
Receptor activation of and signal generation by the lutropin/choriogonadotropin receptor. Cooperation of Asp397 of the receptor and alpha Lys91 of the hormone
-
Ji I, Zeng H, Ji TH. Receptor activation of and signal generation by the lutropin/choriogonadotropin receptor. Cooperation of Asp397 of the receptor and alpha Lys91 of the hormone. J Biol Chem 1993, 268(31):22971-22974.
-
(1993)
J Biol Chem
, vol.268
, Issue.31
, pp. 22971-22974
-
-
Ji, I.1
Zeng, H.2
Ji, T.H.3
-
40
-
-
0025183708
-
Basic local alignment search tool
-
Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ. Basic local alignment search tool. J Mol Biol 1990, 215(3):403-410.
-
(1990)
J Mol Biol
, vol.215
, Issue.3
, pp. 403-410
-
-
Altschul, S.F.1
Gish, W.2
Miller, W.3
Myers, E.W.4
Lipman, D.J.5
-
41
-
-
75849153303
-
The Universal Protein Resource (UniProt) in 2010
-
Database
-
The Universal Protein Resource (UniProt) in 2010. Nucleic Acids Res 2010, (38 Database):D142-148.
-
(2010)
Nucleic Acids Res
, Issue.38
-
-
-
42
-
-
66449084442
-
Infrastructure for the life sciences: design and implementation of the UniProt website
-
10.1186/1471-2105-10-136, 2686714, 19426475
-
Jain E, Bairoch A, Duvaud S, Phan I, Redaschi N, Suzek BE, Martin MJ, McGarvey P, Gasteiger E. Infrastructure for the life sciences: design and implementation of the UniProt website. BMC Bioinformatics 2009, 10:136. 10.1186/1471-2105-10-136, 2686714, 19426475.
-
(2009)
BMC Bioinformatics
, vol.10
, pp. 136
-
-
Jain, E.1
Bairoch, A.2
Duvaud, S.3
Phan, I.4
Redaschi, N.5
Suzek, B.E.6
Martin, M.J.7
McGarvey, P.8
Gasteiger, E.9
-
43
-
-
77957055780
-
Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein coupled receptors
-
Ballesteros JA, W H. Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein coupled receptors. Methods Neurosci 1995, 25:366-428.
-
(1995)
Methods Neurosci
, vol.25
, pp. 366-428
-
-
Ballesteros, J.A.1
W, H.2
-
44
-
-
0003818089
-
HMMER: Profile hidden Markov models for biological sequence analysis
-
HMMER: Profile hidden Markov models for biological sequence analysis. , http://hmmer.janelia.org
-
-
-
-
45
-
-
36448991500
-
Clustal W and Clustal × version 2.0
-
10.1093/bioinformatics/btm404, 17846036
-
Larkin MA, Blackshields G, Brown NP, Chenna R, McGettigan PA, McWilliam H, Valentin F, Wallace IM, Wilm A, Lopez R, et al. Clustal W and Clustal × version 2.0. Bioinformatics 2007, 23(21):2947-2948. 10.1093/bioinformatics/btm404, 17846036.
-
(2007)
Bioinformatics
, vol.23
, Issue.21
, pp. 2947-2948
-
-
Larkin, M.A.1
Blackshields, G.2
Brown, N.P.3
Chenna, R.4
McGettigan, P.A.5
McWilliam, H.6
Valentin, F.7
Wallace, I.M.8
Wilm, A.9
Lopez, R.10
-
46
-
-
36448978229
-
GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function
-
10.1126/science.1150609, 17962519
-
Rosenbaum DM, Cherezov V, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Yao XJ, Weis WI, Stevens RC, et al. GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function. Science 2007, 318(5854):1266-1273. 10.1126/science.1150609, 17962519.
-
(2007)
Science
, vol.318
, Issue.5854
, pp. 1266-1273
-
-
Rosenbaum, D.M.1
Cherezov, V.2
Hanson, M.A.3
Rasmussen, S.G.4
Thian, F.S.5
Kobilka, T.S.6
Choi, H.J.7
Yao, X.J.8
Weis, W.I.9
Stevens, R.C.10
-
47
-
-
0037423211
-
The unique ligand-binding pocket for the human prostacyclin receptor. Site-directed mutagenesis and molecular modeling
-
10.1074/jbc.M207420200, 12446735
-
Stitham J, Stojanovic A, Merenick BL, O'Hara KA, Hwa J. The unique ligand-binding pocket for the human prostacyclin receptor. Site-directed mutagenesis and molecular modeling. J Biol Chem 2003, 278(6):4250-4257. 10.1074/jbc.M207420200, 12446735.
-
(2003)
J Biol Chem
, vol.278
, Issue.6
, pp. 4250-4257
-
-
Stitham, J.1
Stojanovic, A.2
Merenick, B.L.3
O'Hara, K.A.4
Hwa, J.5
-
48
-
-
0035793604
-
An activation switch in the ligand binding pocket of the C5a receptor
-
10.1074/jbc.M007748200, 11062244
-
Gerber BO, Meng EC, Dotsch V, Baranski TJ, Bourne HR. An activation switch in the ligand binding pocket of the C5a receptor. J Biol Chem 2001, 276(5):3394-3400. 10.1074/jbc.M007748200, 11062244.
-
(2001)
J Biol Chem
, vol.276
, Issue.5
, pp. 3394-3400
-
-
Gerber, B.O.1
Meng, E.C.2
Dotsch, V.3
Baranski, T.J.4
Bourne, H.R.5
-
49
-
-
38349184206
-
Targeting the cannabinoid CB2 receptor: modelling and structural determinants of CB2 selective ligands
-
10.1038/sj.bjp.0707567, 2219524, 17982473
-
Poso A, Huffman JW. Targeting the cannabinoid CB2 receptor: modelling and structural determinants of CB2 selective ligands. Br J Pharmacol 2008, 153(2):335-346. 10.1038/sj.bjp.0707567, 2219524, 17982473.
-
(2008)
Br J Pharmacol
, vol.153
, Issue.2
, pp. 335-346
-
-
Poso, A.1
Huffman, J.W.2
-
50
-
-
18444386531
-
Targeting the cannabinoid CB2 receptor: mutations, modeling and development of CB2 selective ligands
-
10.2174/0929867053764617, 15892633
-
Raitio KH, Salo OM, Nevalainen T, Poso A, Jarvinen T. Targeting the cannabinoid CB2 receptor: mutations, modeling and development of CB2 selective ligands. Curr Med Chem 2005, 12(10):1217-1237. 10.2174/0929867053764617, 15892633.
-
(2005)
Curr Med Chem
, vol.12
, Issue.10
, pp. 1217-1237
-
-
Raitio, K.H.1
Salo, O.M.2
Nevalainen, T.3
Poso, A.4
Jarvinen, T.5
-
51
-
-
3843131055
-
Gonadotropin-releasing hormone receptors
-
10.1210/er.2003-0002, 15082521
-
Millar RP, Lu ZL, Pawson AJ, Flanagan CA, Morgan K, Maudsley SR. Gonadotropin-releasing hormone receptors. Endocr Rev 2004, 25(2):235-275. 10.1210/er.2003-0002, 15082521.
-
(2004)
Endocr Rev
, vol.25
, Issue.2
, pp. 235-275
-
-
Millar, R.P.1
Lu, Z.L.2
Pawson, A.J.3
Flanagan, C.A.4
Morgan, K.5
Maudsley, S.R.6
-
52
-
-
35748937333
-
Identification of residues important for agonist recognition and activation in GPR40
-
10.1074/jbc.M705077200, 17699519
-
Sum CS, Tikhonova IG, Neumann S, Engel S, Raaka BM, Costanzi S, Gershengorn MC. Identification of residues important for agonist recognition and activation in GPR40. J Biol Chem 2007, 282(40):29248-29255. 10.1074/jbc.M705077200, 17699519.
-
(2007)
J Biol Chem
, vol.282
, Issue.40
, pp. 29248-29255
-
-
Sum, C.S.1
Tikhonova, I.G.2
Neumann, S.3
Engel, S.4
Raaka, B.M.5
Costanzi, S.6
Gershengorn, M.C.7
-
53
-
-
0036923938
-
Structure modeling of the chemokine receptor CCR5: implications for ligand binding and selectivity
-
10.1016/S0006-3495(02)75307-1, 1302382, 12496074
-
Paterlini MG. Structure modeling of the chemokine receptor CCR5: implications for ligand binding and selectivity. Biophys J 2002, 83(6):3012-3031. 10.1016/S0006-3495(02)75307-1, 1302382, 12496074.
-
(2002)
Biophys J
, vol.83
, Issue.6
, pp. 3012-3031
-
-
Paterlini, M.G.1
-
54
-
-
6044234752
-
Architecture of P2Y nucleotide receptors: structural comparison based on sequence analysis, mutagenesis, and homology modeling
-
10.1021/jm049914c, 15481977
-
Costanzi S, Mamedova L, Gao ZG, Jacobson KA. Architecture of P2Y nucleotide receptors: structural comparison based on sequence analysis, mutagenesis, and homology modeling. J Med Chem 2004, 47(22):5393-5404. 10.1021/jm049914c, 15481977.
-
(2004)
J Med Chem
, vol.47
, Issue.22
, pp. 5393-5404
-
-
Costanzi, S.1
Mamedova, L.2
Gao, Z.G.3
Jacobson, K.A.4
-
55
-
-
34250792472
-
Defining the nucleotide binding sites of P2Y receptors using rhodopsin-based homology modeling
-
417-426
-
Ivanov AA, Costanzi S, Jacobson KA. Defining the nucleotide binding sites of P2Y receptors using rhodopsin-based homology modeling. J Comput Aided Mol Des 2006, 20:(7-8):417-426.
-
(2006)
J Comput Aided Mol Des
, vol.20
, pp. 7-8
-
-
Ivanov, A.A.1
Costanzi, S.2
Jacobson, K.A.3
-
56
-
-
67650753759
-
Definition of the G protein-coupled receptor transmembrane bundle binding pocket and calculation of receptor similarities for drug design
-
10.1021/jm900319e, 19537715
-
Gloriam DE, Foord SM, Blaney FE, Garland SL. Definition of the G protein-coupled receptor transmembrane bundle binding pocket and calculation of receptor similarities for drug design. J Med Chem 2009, 52(14):4429-4442. 10.1021/jm900319e, 19537715.
-
(2009)
J Med Chem
, vol.52
, Issue.14
, pp. 4429-4442
-
-
Gloriam, D.E.1
Foord, S.M.2
Blaney, F.E.3
Garland, S.L.4
-
57
-
-
41349088364
-
Managing bias in ROC curves
-
10.1007/s10822-008-9181-z, 18256892
-
Clark RD, Webster-Clark DJ. Managing bias in ROC curves. J Comput Aided Mol Des 2008, 22(3-4):141-146. 10.1007/s10822-008-9181-z, 18256892.
-
(2008)
J Comput Aided Mol Des
, vol.22
, Issue.3-4
, pp. 141-146
-
-
Clark, R.D.1
Webster-Clark, D.J.2
|