An Activation Switch in the Ligand Binding Pocket of the C5a Receptor

Journal of Biological Chemistry

Volumn 276, Issue 5, 2001, Pages 3394-3400

  Gerber, Basil O ^a   Meng, Elaine C ^a   Dötsch, Volker ^a,b   Baranski, Thomas J ^a,c   Bourne, Henry R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUNDS; BINDING ENERGY; POLYPEPTIDES; PROTEINS;

LIGANDS; MUTANTS;

BIOCHEMISTRY;

ALANINE DERIVATIVE; COMPLEMENT COMPONENT C5A; COMPLEMENT COMPONENT C5A RECEPTOR; CYCLOHEXYLALANINE; GUANINE NUCLEOTIDE BINDING PROTEIN; HEXAPEPTIDE; LIGAND; TRYPTOPHAN; UNCLASSIFIED DRUG; ALANINE; COMPLEMENT RECEPTOR; ISOLEUCINE; LEUKOCYTE ANTIGEN; PEPTIDE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; COMPLEMENT SYSTEM; LIGAND BINDING; MAMMAL CELL; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SACCHAROMYCES CEREVISIAE; YEAST; ANIMAL; CELL STRAIN COS1; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; MUTATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHYSIOLOGY; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION;

ANIMALIA; MAMMALIA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

ALANINE; ANIMALS; ANTIGENS, CD; BINDING SITES; COS CELLS; ISOLEUCINE; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MUTATION; PEPTIDES; PROTEIN CONFORMATION; RECEPTOR, ANAPHYLATOXIN C5A; RECEPTORS, COMPLEMENT; SIGNAL TRANSDUCTION;

EID: 0035793604     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M007748200     Document Type: Article

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