메뉴 건너뛰기




Volumn 11, Issue 10, 2011, Pages 2012-2019

The emerging role of the TIM molecules in transplantation

Author keywords

Costimulatory molecules; T cell activation; T cell immunoglobulin mucin (TIM) family; transplant immunology

Indexed keywords

MUCIN; T CELL IMMUNOGLOBULIN MUCIN 1; T CELL IMMUNOGLOBULIN MUCIN 3; T CELL IMMUNOGLOBULIN MUCIN 4; UNCLASSIFIED DRUG;

EID: 80053317125     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2011.03727.x     Document Type: Review
Times cited : (41)

References (52)
  • 1
    • 77951673268 scopus 로고    scopus 로고
    • TIM genes: A family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity
    • Freeman GJ, Casasnovas JM, Umetsu DT, DeKruyff RH,. TIM genes: A family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity. Immunol Rev 2010; 235: 172-189.
    • (2010) Immunol Rev , vol.235 , pp. 172-189
    • Freeman, G.J.1    Casasnovas, J.M.2    Umetsu, D.T.3    Dekruyff, R.H.4
  • 9
    • 23144447812 scopus 로고    scopus 로고
    • The TIM gene family regulates autoimmune and allergic diseases
    • DOI 10.1016/j.molmed.2005.06.008, PII S1471491405001383
    • Meyers JH, Sabatos CA, Chakravarti S, Kuchroo VK,. The TIM gene family regulates autoimmune and allergic diseases. Trends Mol Med 2005; 11: 362-369. (Pubitemid 41080577)
    • (2005) Trends in Molecular Medicine , vol.11 , Issue.8 , pp. 362-369
    • Meyers, J.H.1    Sabatos, C.A.2    Chakravarti, S.3    Kuchroo, V.K.4
  • 10
    • 28044460035 scopus 로고    scopus 로고
    • T cell Ig and mucin 1 (TIM-1) is expressed on in vivo-activated T cells and provides a costimulatory signal for T cell activation
    • De Souza AJ, Oriss TB, O'Malley KJ, Ray A, Kane LP,. T cell Ig and mucin 1 (TIM-1) is expressed on in vivo-activated T cells and provides a costimulatory signal for T cell activation. Proc Natl Acad Sci U S A 2005; 102: 1713-1718.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 1713-1718
    • De Souza, A.J.1    Oriss, T.B.2    O'Malley, K.J.3    Ray, A.4    Kane, L.P.5
  • 12
    • 44449145064 scopus 로고    scopus 로고
    • TIM-4 expressed on APCs induces T cell expansion and survival
    • Rodriguez-Manzanet R, Meyers JH, Balasubramanian S, et al,. TIM-4 expressed on APCs induces T cell expansion and survival. J Immunol 2008; 180: 4706-4713.
    • (2008) J Immunol , vol.180 , pp. 4706-4713
    • Rodriguez-Manzanet, R.1    Meyers, J.H.2    Balasubramanian, S.3
  • 13
    • 45549085191 scopus 로고    scopus 로고
    • T cell Ig and mucin domain-1-mediated T cell activation requires recruitment and activation of phosphoinositide 3-kinase
    • De Souza AJ, Oak JS, Jordanhazy R, DeKruyff RH, Fruman DA, Kane LP,. T cell Ig and mucin domain-1-mediated T cell activation requires recruitment and activation of phosphoinositide 3-kinase. J Immunol 2008; 180: 6518-6526.
    • (2008) J Immunol , vol.180 , pp. 6518-6526
    • De Souza, A.J.1    Oak, J.S.2    Jordanhazy, R.3    Dekruyff, R.H.4    Fruman, D.A.5    Kane, L.P.6
  • 14
    • 63149153478 scopus 로고    scopus 로고
    • Tim-1 signaling substitutes for conventional signal 1 and requires costimulation to induce T cell proliferation
    • Mariat C, Degauque N, Balasubramanian S, et al,. Tim-1 signaling substitutes for conventional signal 1 and requires costimulation to induce T cell proliferation. J Immunol 2009; 182: 1379-1385.
    • (2009) J Immunol , vol.182 , pp. 1379-1385
    • Mariat, C.1    Degauque, N.2    Balasubramanian, S.3
  • 15
    • 33947617935 scopus 로고    scopus 로고
    • Human TIM-1 associates with the TCR complex and up-regulates T cell activation signals
    • Binne LL, Scott ML, Rennert PD,. Human TIM-1 associates with the TCR complex and up-regulates T cell activation signals. J Immunol 2007; 178: 4342-4343.
    • (2007) J Immunol , vol.178 , pp. 4342-4343
    • Binne, L.L.1    Scott, M.L.2    Rennert, P.D.3
  • 18
    • 35648938123 scopus 로고    scopus 로고
    • TIM-4 Expressed by Mucosal Dendritic Cells Plays a Critical Role in Food Antigen-Specific Th2 Differentiation and Intestinal Allergy
    • DOI 10.1053/j.gastro.2007.08.006, PII S0016508507014527
    • Yang PC, Xing Z, Berin CM, et al,. TIM-4 expressed by mucosal dendritic cells plays a critical role in food antigen-specific Th2 differentiation and intestinal allergy. Gastroenterology 2007; 133: 1522-1533. (Pubitemid 350029737)
    • (2007) Gastroenterology , vol.133 , Issue.5 , pp. 1522-1533
    • Yang, P.1    Xing, Z.2    Berin, C.M.3    Soderholm, J.D.4    Feng, B.5    Wu, L.6    Yeh, C.7
  • 19
    • 46049095214 scopus 로고    scopus 로고
    • Disruption of T-cell immunoglobulin and mucin domain molecule (TIM)-1/TIM4 interaction as a therapeutic strategy in a dendritic cell-induced peanut allergy model
    • Feng BS, Chen X, He SH, et al,. Disruption of T-cell immunoglobulin and mucin domain molecule (TIM)-1/TIM4 interaction as a therapeutic strategy in a dendritic cell-induced peanut allergy model. J Allergy Clin Immunol 2008; 122: 55-61.e7.
    • (2008) J Allergy Clin Immunol , vol.122
    • Feng, B.S.1    Chen, X.2    He, S.H.3
  • 25
    • 40849120400 scopus 로고    scopus 로고
    • Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis
    • Seki M, Oomizu S, Sakata KM, et al,. Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis. Clin Immunol 2008; 127: 78-88.
    • (2008) Clin Immunol , vol.127 , pp. 78-88
    • Seki, M.1    Oomizu, S.2    Sakata, K.M.3
  • 26
    • 70349248367 scopus 로고    scopus 로고
    • TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines
    • Hastings WD, Anderson DE, Kassam N, et al,. TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines. Eur J Immunol 2009; 39: 2492-2501.
    • (2009) Eur J Immunol , vol.39 , pp. 2492-2501
    • Hastings, W.D.1    Anderson, D.E.2    Kassam, N.3
  • 27
    • 78650635632 scopus 로고    scopus 로고
    • TIM-3: A novel regulatory molecule of alloimmune activation
    • Boenisch O, D'Addio F, Watanabe T, et al,. TIM-3: A novel regulatory molecule of alloimmune activation. J Immunol 2010; 185: 5806-5819
    • (2010) J Immunol , vol.185 , pp. 5806-5819
    • Boenisch, O.1    D'Addio, F.2    Watanabe, T.3
  • 29
    • 0037203867 scopus 로고    scopus 로고
    • Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease
    • Monney L, Sabatos CA, Gaglia JL, et al,. Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease. Nature 2002; 415: 536-5341.
    • (2002) Nature , vol.415 , pp. 536-5341
    • Monney, L.1    Sabatos, C.A.2    Gaglia, J.L.3
  • 30
    • 78649703973 scopus 로고    scopus 로고
    • T-cell immunoglobulin mucin-3 determines severity of liver ischemia/reperfusion injury in mice in a TLR4-dependent manner
    • Uchida Y, Ke B, Freitas MC, et al,. T-cell immunoglobulin mucin-3 determines severity of liver ischemia/reperfusion injury in mice in a TLR4-dependent manner. Gastroenterology 2010; 139: 2195-2206.
    • (2010) Gastroenterology , vol.139 , pp. 2195-2206
    • Uchida, Y.1    Ke, B.2    Freitas, M.C.3
  • 31
    • 78650661684 scopus 로고    scopus 로고
    • TIM-4, a receptor for phosphatidylserine, controls adaptive immunity by regulating the removal of antigen-specific T cells
    • Albacker LA, Karisola P, Chang YJ, et al,. TIM-4, a receptor for phosphatidylserine, controls adaptive immunity by regulating the removal of antigen-specific T cells. J Immunol 2010; 185: 6839-6849
    • (2010) J Immunol , vol.185 , pp. 6839-6849
    • Albacker, L.A.1    Karisola, P.2    Chang, Y.J.3
  • 32
    • 65549168745 scopus 로고    scopus 로고
    • Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation
    • Nakayama M, Akiba H, Takeda K, et al,. Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation. Blood 2009; 113: 3821-3830.
    • (2009) Blood , vol.113 , pp. 3821-3830
    • Nakayama, M.1    Akiba, H.2    Takeda, K.3
  • 34
    • 67649784846 scopus 로고    scopus 로고
    • Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells
    • Yuan X, Ansari MJ, D'Addio F, et al,. Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells. Proc Natl Acad Sci U S A 2009; 106: 10734-10739.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 10734-10739
    • Yuan, X.1    Ansari, M.J.2    D'Addio, F.3
  • 36
    • 78149486214 scopus 로고    scopus 로고
    • Apoptotic cells activate NKT cells through T cell Ig-like mucin-like-1 resulting in airway hyperreactivity
    • Lee HH, Meyer EH, Goya S, et al,. Apoptotic cells activate NKT cells through T cell Ig-like mucin-like-1 resulting in airway hyperreactivity. J Immunol 2010; 185: 5225-5235.
    • (2010) J Immunol , vol.185 , pp. 5225-5235
    • Lee, H.H.1    Meyer, E.H.2    Goya, S.3
  • 37
    • 80052382391 scopus 로고    scopus 로고
    • Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice
    • [Epub ahead of print]
    • Ding Q, Yeung M, Camirand G, et al,. Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice. J Clin Invest 2011; [Epub ahead of print].
    • (2011) J Clin Invest
    • Ding, Q.1    Yeung, M.2    Camirand, G.3
  • 38
    • 64049088217 scopus 로고    scopus 로고
    • Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells
    • Wang F, Wan L, Zhang C, Zheng X, Li J, Chen ZK,. Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells. Immunobiology 2009; 214: 342-349.
    • (2009) Immunobiology , vol.214 , pp. 342-349
    • Wang, F.1    Wan, L.2    Zhang, C.3    Zheng, X.4    Li, J.5    Chen, Z.K.6
  • 40
    • 42649122277 scopus 로고    scopus 로고
    • In primed allo-tolerance, TIM-3-Ig rapidly suppresses TGFβ, but has no immediate effect on Foxp3
    • DOI 10.1111/j.1432-2277.2008.00654.x
    • Muthukumarana PA, Zheng XX, Rosengard BR, Strom TB, Metcalfe SM,. In primed allo-tolerance, TIM-3-Ig rapidly suppresses TGFbeta, but has no immediate effect on Foxp3. Transpl Int 2008; 21: 593-597. (Pubitemid 351600069)
    • (2008) Transplant International , vol.21 , Issue.6 , pp. 593-597
    • Muthukumarana, P.A.D.S.1    Zheng, X.X.2    Rosengard, B.R.3    Strom, T.B.4    Metcalfe, S.M.5
  • 42
    • 40849083349 scopus 로고    scopus 로고
    • Activation of Tim-3-Galectin-9 pathway improves survival of fully allogeneic skin grafts
    • Wang F, He W, Yuan J, et al,. Activation of Tim-3-Galectin-9 pathway improves survival of fully allogeneic skin grafts. Transpl Immunol 2008; 19: 12-19.
    • (2008) Transpl Immunol , vol.19 , pp. 12-19
    • Wang, F.1    He, W.2    Yuan, J.3
  • 43
    • 70350552096 scopus 로고    scopus 로고
    • Galectin-9 significantly prolongs the survival of fully mismatched cardiac allografts in mice
    • He W, Fang Z, Wang F, et al,. Galectin-9 significantly prolongs the survival of fully mismatched cardiac allografts in mice. Transplantation 2009; 88: 782-790.
    • (2009) Transplantation , vol.88 , pp. 782-790
    • He, W.1    Fang, Z.2    Wang, F.3
  • 44
    • 77949887317 scopus 로고    scopus 로고
    • Tubular expression of KIM-1 does not predict delayed function after transplantation
    • Schroppel B, Kruger B, Walsh L, et al,. Tubular expression of KIM-1 does not predict delayed function after transplantation. J Am Soc Nephrol 2010; 21: 536-542
    • (2010) J Am Soc Nephrol , vol.21 , pp. 536-542
    • Schroppel, B.1    Kruger, B.2    Walsh, L.3
  • 45
    • 67650935680 scopus 로고    scopus 로고
    • Kidney injury molecule-1 is an early noninvasive indicator for donor brain death-induced injury prior to kidney transplantation
    • Nijboer WN, Schuurs TA, Damman J, et al,. Kidney injury molecule-1 is an early noninvasive indicator for donor brain death-induced injury prior to kidney transplantation. Am J Transplant 2009; 9: 1752-1759.
    • (2009) Am J Transplant , vol.9 , pp. 1752-1759
    • Nijboer, W.N.1    Schuurs, T.A.2    Damman, J.3
  • 46
    • 75149180130 scopus 로고    scopus 로고
    • IL-18 and urinary NGAL predict dialysis and graft recovery after kidney transplantation
    • Hall IE, Yarlagadda SG, Coca SG, et al,. IL-18 and urinary NGAL predict dialysis and graft recovery after kidney transplantation. J Am Soc Nephrol 2010; 21: 189-197
    • (2010) J Am Soc Nephrol , vol.21 , pp. 189-197
    • Hall, I.E.1    Yarlagadda, S.G.2    Coca, S.G.3
  • 47
    • 47649114657 scopus 로고    scopus 로고
    • Increased T cell immunoglobulin mucin-3 and its ligand in acquired aplastic anemia
    • DOI 10.1111/j.1600-0609.2008.01095.x
    • Zhang J, Gu Y, Xu C, Qu X,. Increased T cell immunoglobulin mucin-3 and its ligand in acquired aplastic anemia. Eur J Haematol 2008; 81: 130-139. (Pubitemid 352019637)
    • (2008) European Journal of Haematology , vol.81 , Issue.2 , pp. 130-139
    • Zhang, J.1    Gu, Y.2    Xu, C.3    Qu, X.4
  • 48
    • 37549009988 scopus 로고    scopus 로고
    • High urinary excretion of kidney injury molecule-1 is an independent predictor of graft loss in renal transplant recipients
    • van Timmeren MM, Vaidya VS, van Ree RM, et al,. High urinary excretion of kidney injury molecule-1 is an independent predictor of graft loss in renal transplant recipients. Transplantation 2007; 84: 1625-1630.
    • (2007) Transplantation , vol.84 , pp. 1625-1630
    • Van Timmeren, M.M.1    Vaidya, V.S.2    Van Ree, R.M.3
  • 49
    • 78650381320 scopus 로고    scopus 로고
    • Urinary expression of kidney injury markers in renal transplant recipients
    • Szeto CC, Kwan BC, Lai KB, et al,. Urinary expression of kidney injury markers in renal transplant recipients. Clin J Am Soc Nephrol 2010; 5: 2329-2337.
    • (2010) Clin J Am Soc Nephrol , vol.5 , pp. 2329-2337
    • Szeto, C.C.1    Kwan, B.C.2    Lai, K.B.3
  • 52
    • 34248640135 scopus 로고    scopus 로고
    • High expression of Tim-3 mRNA in urinary cells from kidney transplant recipients with acute rejection
    • DOI 10.1111/j.1600-6143.2007.01795.x
    • Renesto PG, Ponciano VC, Cenedeze MA, Saraiva Camara NO, Pacheco-Silva A,. High expression of Tim-3 mRNA in urinary cells from kidney transplant recipients with acute rejection. Am J Transplant 2007; 7: 1661-1665. (Pubitemid 46776247)
    • (2007) American Journal of Transplantation , vol.7 , Issue.6 , pp. 1661-1665
    • Renesto, P.G.1    Ponciano, V.C.2    Cenedeze, M.A.3    Camara, N.O.S.4    Pacheco-Silva, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.