Latent specificity of molecular recognition in sodium channels engineered to discriminate between two "indistinguishable" μ-Conotoxins

Biochemistry

Volumn 40, Issue 20, 2001, Pages 6002-6008

  Li, Ronald A ^a   Ennis, Irene L ^a   Tomaselli, Gordon F ^a   French, Robert J ^b   Marbán, Eduardo ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSENSORS; BIOSYNTHESIS; SODIUM;

MOLECULAR RECOGNITION;

BIOCHEMISTRY;

OMEGA CONOTOXIN; SODIUM CHANNEL;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CHANNEL GATING; CONTROLLED STUDY; MOLECULAR RECOGNITION; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT; SKELETAL MUSCLE; TOXIN STRUCTURE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ARGININE; ASPARTIC ACID; CONOTOXINS; GLUTAMIC ACID; GLUTAMINE; LYSINE; MEMBRANE POTENTIALS; MOLECULAR SEQUENCE DATA; MOLLUSK VENOMS; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; PROTEIN BINDING; RATS; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; THERMODYNAMICS;

EID: 0035918530     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi010077f     Document Type: Article

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