Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 37, 2011, Pages 15354-15359

  Goodwin, Andrew C ^a   Destefano Shields, Christina E ^a   Wu, Shaoguang ^a   Huso, David L ^a   Wu, XinQun ^a   Murray Stewart, Tracy R ^a   Hacker Prietz, Amy ^a   Rabizadeh, Shervin ^a   Woster, Patrick M ^b   Sears, Cynthia L ^a   Casero Jr , Robert A ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Adenomatous polyposis coli; Inflammatory bowel diseases

Indexed keywords

FRAGILYSIN; H2 ANTIGEN; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 23; INTERLEUKIN 23P19; N,N' BIS(2,3 BUTADIENYL)PUTRESCINE; REACTIVE OXYGEN METABOLITE; SPERMINE DERIVATIVE; SPERMINE OXIDASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTEROIDES FRAGILIS; CANCER PREVENTION; CANCER RISK; CATABOLISM; CELL DIFFERENTIATION; CELL PROLIFERATION; CHRONIC INFLAMMATION; COLITIS; COLON CARCINOGENESIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE MARKER; DNA DAMAGE; ENTERITIS; EPITHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; POLYAMINE METABOLISM; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

ACETYLTRANSFERASES; ANIMALS; BACTERIAL TOXINS; BACTEROIDES FRAGILIS; CELL LINE; CELL PROLIFERATION; COLITIS; COLONIC NEOPLASMS; DISEASE MODELS, ANIMAL; DNA DAMAGE; ENZYME INDUCTION; EPITHELIAL CELLS; HUMANS; INFLAMMATION; INTESTINES; MICE; MICE, INBRED C57BL; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; POLYAMINES; PRECANCEROUS CONDITIONS; PUTRESCINE; RECOMBINANT PROTEINS;

BACTERIA (MICROORGANISMS); BACTEROIDES FRAGILIS; MUS;

EID: 80053079336     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1010203108     Document Type: Article

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