Properties of recombinant human N1-acetylpolyamine oxidase (hPAO): Potential role in determining drug sensitivity

Cancer Chemotherapy and Pharmacology

Volumn 56, Issue 1, 2005, Pages 83-90

  Wang, Yanlin ^a   Hacker, Amy ^a   Murray Stewart, Tracy ^a   Frydman, Benjamin ^b   Valasinas, Aldonia ^b   Fraser, Alison V ^a   Woster, Patrick M ^c   Casero Jr , Robert A ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b SLIL Biomedical Corp   (United States)

^c WAYNE STATE UNIVERSITY   (United States)

Author keywords

FAD dependent; H2O2; Polyamines; Spermidine spermine N1 acetyltransferase

Indexed keywords

AMINE; ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; HUMAN N1 ACETYLPOLYAMINE OXIDASE; N 1 (2 METHYL 1 BUTYL) 4,8 DIAZAUNDECANE; N 1 ETHYL N 11 (CYCLOHEPTYL)METHYL 4,8 DIAZAUNDECANE; N 1 ETHYL N 11 (CYCLOPROPYL)METHYL 4,8 DIAZAUNDECANE; N 1,N 11 DIETHYLNORSPERMINE; N,N' BIS(2,3 BUTADIENYL)PUTRESCINE; N1 ACETYLSPERMIDINE; POLYAMINE DERIVATIVE; POLYAMINE OXIDASE; RECOMBINANT ENZYME; SL 11093; SL 11144; SL 11150; SL 11156; SL 11158; SPERMINE; SPERMINE DERIVATIVE; SPERMINE OXIDASE; TUMOR MARKER; UNCLASSIFIED DRUG; N(1) ACETYLPOLYAMINE OXIDASE, HUMAN; N(1)-ACETYLPOLYAMINE OXIDASE, HUMAN; OXIDOREDUCTASE; POLYAMINE; RECOMBINANT PROTEIN;

ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CATABOLISM; DRUG RESPONSE; DRUG SENSITIVITY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME SYNTHESIS; GENETIC TRANSFECTION; HOMEOSTASIS; HUMAN; HUMAN CELL; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENSITIVITY ANALYSIS; CELL CULTURE; DRUG RESISTANCE; GENETICS; LUNG TUMOR; METABOLISM; OXIDATION REDUCTION REACTION; PATHOLOGY;

DRUG RESISTANCE, NEOPLASM; HOMEOSTASIS; HUMANS; LUNG NEOPLASMS; OXIDATION-REDUCTION; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; POLYAMINES; RECOMBINANT PROTEINS; SPERMINE; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 21244483811     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-004-0936-5     Document Type: Article

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