The role of polyamine metabolism in neuronal injury following cerebral ischemia

Canadian Journal of Neurological Sciences

Volumn 36, Issue 1, 2009, Pages 14-19

  Kim, Grace H ^a   Komotar, Ricardo J ^a   McCullough Hicks, Margy E ^a   Otten, Marc L ^a   Starke, Robert M ^a   Kellner, Christopher P ^a   Garrett, Matthew C ^a   Merkow, Maxwell B ^a   Rynkowski, Michal ^a   Dash, Kelly A ^a   Connolly, E Sander ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACROLEIN; ALDEHYDE; AMINE OXIDASE (FLAVIN CONTAINING); AMINOGUANIDINE; CHLOROQUINE; CYTOTOXIN; HYDRALAZINE; ORNITHINE DECARBOXYLASE; PHOSPHOLIPASE A2; POLYAMINE OXIDASE; PUTRESCINE; REACTIVE OXYGEN METABOLITE; SPERMIDINE; SPERMINE;

AEROBIC METABOLISM; BLOOD BRAIN BARRIER; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN LEVEL; BRAIN MITOCHONDRION; BRAIN PROTECTION; BRAIN VASOSPASM; CALCIUM CELL LEVEL; CELL DEATH; CYTOTOXICITY; DISEASE SEVERITY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; MITOCHONDRIAL RESPIRATION; NONHUMAN; POLYAMINE METABOLISM; POLYAMINE SYNTHESIS; PRIORITY JOURNAL; PROGNOSIS; REGULATORY MECHANISM; REVIEW;

EID: 61349195975     PISSN: 03171671     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0317167100006247     Document Type: Review

References (36)

1. Adibhatla RM, Hatcher JF, Dempsey RJ. Phospholipase A2, hydroxyl radicals, and lipid peroxidation in transient cerebral ischemia. Antioxid Redox Signal. 2003 Oct;5(5):647-54,
2. Ivanova S, Batliwalla F, Mocco J, Kiss S, Huang J, Mack W, et al. Neuroprotection in cerebral ischemia by neutralization of 3-aminopropanal. Proc Natl Acad Sci USA. 2002 Apr 16;99(8): 5579-84.
3. Goodenough S, Davidson M, Kidd G, Matsumoto I, Wilce P. Cell death and immunohistochemistry of p53, c-Fos and c-Jun after spermine injection into the rat striatum. Exp Brain Res. 2000 Mar;131(1):126-34.
4. Slotkin TA, Bartolome J. Role of ornithine decarboxylase and the polyamines in nervous system development: a review. Brain Res Bull. 1986 Sep;17(3):307-20.
5. Iqbal Z, Koenig H. Polyamines appear to be second messengers in mediating Ca2+ fluxes and neurotransmitter release in potassium-depolarized synaptosomes. Biochem Biophys Res Commun. 1985 Dec 17;133(2):563-73.
6. Rock DM, Macdonald RL. Polyamine regulation of N-methyl-D-aspartate receptor channels. Anim Rev Pharmacol Toxicol. 1995; 35:463-82.
7. Williams K, Romano C, Molinoff PB. Effects of polyamines on the binding of [3H]MK-801 to the N-methyl-D-aspartate receptor: pharmacological evidence for the existence of a polyamine recognition site. Mol Pharmacol. 1989 Oct;36(4):575-81.
8. Seiler N. Polyamine oxidase, properties and functions. Prog Brain Res. 1995;106:333-44.
9. Ferioli ME, Berselli D, Caimi S. Effect of mitoguazone on polyamine oxidase activity in rat liver. Toxicol Appl Pharmacol. 2004 Dec 1;201(2):105-11.
10. Takano K, Ogura M, Yoneda Y, Nakamura Y. Oxidative metabolites are involved in polyamine-induced microglial cell death. Neuroscience. 2005;134(4):1123-31.
11. Nagesh Babu G, Sailor KA, Sun D, Dempsey RJ. Spermidine/spermine N1-acetyl transferase activity in rat brain following transient focal cerebral ischemia and reperfusion. Neurosci Lett. 2001 Mar 2;300(1):17-20.
12. Tomitori H, Usui T, Saeki N, Ueda S, Kase H, Nishimura K, et al. Polyamine oxidase and acrolein as novel biochemdcal markers for diagnosis of cerebral stroke. Stroke. 2005 Dec;36(12): 2609-13.
13. Alarcon RA. Acrolein. IV. Evidence for the formation of the cytotoxic aldehyde acrolein from enzymatically oxidized spermine or spermidine. Arch Biochem Biophys. 1970 Apr; 137(2):365-72.
14. Wallace HM, Fraser AV. Inhibitors of polyamine metabolism: review article. Amino Acids. 2004 Jul;26(4):353-65.
15. Seiler N. Catabolism of polyamines. Amino Acids. 2004 Jun;26(3): 217-33.
16. Paschen W. Polyamine metabolism in different pathological states of the brain. Mol Chem Neuropathol. 1992 Jun;16(3):241-71.
17. Cockroft KM, Meistrell M, 3rd, Zimmerman GA, Risucci D, Bloom O, Cerami A, et al. Cerebroprotective effects of aminoguanidine in a rodent model of stroke. Stroke. 1996 Aug;27(8):1393-8.
18. Temiz C, Dogan A, Baskaya MK, Dempsey RJ. Effect of difluoromethylornithine on reperfusion injury after temporary middle cerebral artery occlusion. J Clin Neurosci. 2005 May;12(4): 449-52.
19. Wood PL, Khan MA, Kulow SR, Mahmood SA, Moskal JR. Neurotoxicity of reactive aldehydes: the concept of "aldehyde load" as demonstrated by neuroprotection with hydroxylamines. Brain Res. 2006 Jun 20;1095(1):190-9.
20. Paschen W, Schmidt-Kastner R, Djuricic B, Meese C, Linn F, Hossmann KA. Polyamine changes in reversible cerebral ischemia. J Neurochem. 1987 Jul;49(1):35-7.
21. Takano K, Ogura M, Nakamura Y, Yoneda Y. Neuronal and glial responses to polyamines in the ischemic brain. Curr Neurovasc Res. 2005 Jul;2(3):213-23.
22. Ivanova S, Botchkina GI, Al-Abed Y, Meistrell M, 3rd, Batliwalla F, Dubinsky JM, et al. Cerebral ischemia enhances polyamine oxidation: identification of enzymatically formed 3-amino-propanal as an endogenous mediator of neuronal and glial cell death. J Exp Med. 1998 Jul 20;188(2):327-40.
23. Peasley MA, Shi R. Ischemic insult exacerbates acrolein-induced conduction loss and axonal membrane disruption in guinea pig spinal cord white matter. J Neurol Sci. 2003 Dec 15;216(1): 23-32.
24. Li W, Yuan XM, Ivanova S, Tracey KJ, Eaton JW, Brunk UT. 3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin. Biochem J. 2003 Apr 15;371(Pt 2): 429-36.
25. Echlin F. Experimental vasospasm, acute and chronic, due to blood in the subarachnoid space. J Neurosurg. 1971 Dec;35(6):646-56.
26. Conklin DJ, Boyce CL, Trent MB, Boor PJ. Amine metabolism: a novel path to coronary artery vasospasm. Toxicol Appl Pharmacol. 2001 Sep 1;175(2):149-59.
27. Liu-Snyder P, McNally H, Shi R, Borgens RB. Acrolein-mediated mechanisms of neuronal death. J Neurosci Res. 2006 Jul;84(1): 209-18.
28. Liu-Snyder P, Borgens RB, Shi R. Hydralazine rescues PC12 cells from acrolein-mediated death. J Neurosci Res. 2006 Jul;84(1): 219-27.
29. Tanel A, Averill-Bates DA. P38 and ERK mitogen-activated protein kinases mediate acrolein-induced apoptosis in Chinese hamster ovary cells. Cell Signal. 2007 May;19(5):968-77.
30. Finkelstein EI, Nardini M, van der Vliet A. Inhibition of neutrophil apoptosis by acrolein: a mechanism of tobacco-related lung disease? Am J Physiol Lung Cell Mol Physiol. 2001 Sep;281(3): L732-9.
31. Li L, Hamilton RF, Jr., Taylor DE, Holian A. Acrolein-induced cell death in human alveolar macrophages. Toxicol Appl Pharmacol. 1997 Aug;145(2):331-9.
32. Picklo MJ, Montine TJ. Acrolein inhibits respiration in isolated brain mitochondria. Biochim Biophys Acta. 2001 Feb 14;1535 (2):145-52.
33. Zollner H. Inhibition of some mitochondrial functions by acrolein and methylvinylketone. Biochem Pharmacol. 1973 May 15;22 (10):1171-8.
34. Harper ME, Bevilacqua L, Hagopian K, Weindruch R, Ramsey JJ. Ageing, oxidative stress, and mitochondrial uncoupling. Acta Physiol Scand. 2004 Dec;182(4):321-31.
35. Luo J, Shi R. Acrolein induces oxidative stress in brain mitochondria. Neurochem Int. 2005 Feb;46(3):243-52.
36. Hurtado O, Cardenas A, Pradillo JM, Morales JR, Ortego F, Sobrino T, et al. A chronic treatment with CDP-choline improves functional recovery and increases neuronal plasticity after experimental stroke. Neurobiol Dis. 2007 Apr;26(1):105-11.