Tripartite motif 24 (Trim24/Tif1α) tumor suppressor protein is a novel negative regulator of interferon (IFN)/signal transducers and activators of transcription (STAT) signaling pathway acting through retinoic acid receptor α (Rarα) inhibition

Journal of Biological Chemistry

Volumn 286, Issue 38, 2011, Pages 33369-33379

  Tisserand, Johan ^a   Khetchoumian, Konstantin ^a,b   Thibault, Christelle ^a   Dembélé, Doulaye ^a   Chambon, Pierre ^a   Losson, Régine ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GENETIC STUDIES; HEPATOCARCINOGENESIS; LIVER CANCERS; NEGATIVE REGULATORS; NUCLEAR RECEPTORS; RETINOIC ACID RECEPTORS; SIGNALING PATHWAYS; TRIPARTITE MOTIFS; TUMOR SUPPRESSOR PROTEINS; TUMORIGENESIS;

ANTIBIOTICS; CELL PROLIFERATION; GLYCOPROTEINS; MAMMALS; TUMORS;

TRANSCRIPTION;

RETINOIC ACID RECEPTOR ALPHA; STAT PROTEIN; TRANSCRIPTIONAL INTERMEDIARY FACTOR 1ALPHA; TRIPARTITE MOTIF 24; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; GENE DELETION; GENE EXPRESSION REGULATION; KNOCKOUT MOUSE; LIVER CANCER; LIVER CARCINOGENESIS; LIVER CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STAT1 GENE; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; TRIM24 GENE; TUMOR SUPPRESSOR GENE;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CLUSTER ANALYSIS; GENE DOSAGE; GENE EXPRESSION REGULATION; HUMANS; INTERFERONS; LIVER; LIVER NEOPLASMS; MICE; MODELS, BIOLOGICAL; NUCLEAR PROTEINS; RECEPTORS, RETINOIC ACID; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTOME; TRETINOIN;

MUS;

EID: 80053023388     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.225680     Document Type: Article

References (56)

1. Huynh, H. (2010) Biochem. Pharmacol. 80, 550-560
2. Trevisani, F., Cantarini, M. C., Wands, J. R., and Bernardi, M. (2008) Carcinogenesis 29, 1299-1305
3. Kensler, T. W., Qian, G. S., Chen, J. G., and Groopman, J. D. (2003) Nat. Rev. Cancer 3, 321-329
4. Coulouarn, C., Factor, V. M., and Thorgeirsson, S. S. (2008) Hepatology 47, 2059-2067
5. Thorgeirsson, S. S., Lee, J. S., and Grisham, J. W. (2006) Hepatology 43, S145-150
6. Miki, T., Fleming, T. P., Crescenzi, M., Molloy, C. J., Blam, S. B., Reynolds, S. H., and Aaronson, S. A. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 5167-5171
7. Le Douarin, B., Zechel, C., Garnier, J. M., Lutz, Y., Tora, L., Pierrat, P., Heery, D., Gronemeyer, H., Chambon, P., and Losson, R. (1995) EMBO J. 14, 2020-2033
8. Le Douarin, B., Nielsen, A. L., Garnier, J. M., Ichinose, H., Jeanmougin, F., Losson, R., and Chambon, P. (1996) EMBO J. 15, 6701-6715
9. Nielsen, A. L., Ortiz, J. A., You, J., Oulad-Abdelghani, M., Khechumian, R., Gansmuller, A., Chambon, P., and Losson, R. (1999) EMBO J. 18, 6385-6395
10. Beckstead, R., Ortiz, J. A., Sanchez, C., Prokopenko, S. N., Chambon, P., Losson, R., and Bellen, H. J. (2001) Mol. Cell 7, 753-765
11. Zhong, S., Delva, L., Rachez, C., Cenciarelli, C., Gandini, D., Zhang, H., Kalantry, S., Freedman, L. P., and Pandolfi, P. P. (1999) Nat. Genet. 23, 287-295
12. Teyssier, C., Ou, C. Y., Khetchoumian, K., Losson, R., and Stallcup, M. R. (2006) Mol. Endocrinol. 20, 1276-1286
13. Tsai, W. W., Wang, Z., Yiu, T. T., Akdemir, K. C., Xia, W., Winter, S., Tsai, C. Y., Shi, X., Schwarzer, D., Plunkett, W., Aronow, B., Gozani, O., Fischle, W., Hung, M. C., Patel, D. J., and Barton, M. C. (2010) Nature 468, 927-932
14. Chambon, P. (2005) Mol. Endocrinol. 19, 1418-1428
15. Chelbi-Alix, M. K., and Pelicano, L. (1999) Leukemia 13, 1167-1174
16. Khetchoumian, K., Teletin, M., Tisserand, J., Mark, M., Herquel, B., Ignat, M., Zucman-Rossi, J., Cammas, F., Lerouge, T., Thibault, C., Metzger, D., Chambon, P., and Losson, R. (2007) Nat. Genet. 39, 1500-1506
17. Khetchoumian, K., Teletin, M., Tisserand, J., Herquel, B., Ouararhni, K., and Losson, R. (2008) Cell Cycle 7, 3647-3652
18. Herquel, B., Ouararhni, K., Khetchoumian, K., Ignat, M., Teletin, M., Mark, M., Béchade, G., Van Dorsselaer, A., Sanglier-Cianférani, S., Hamiche, A., Cammas, F., Davidson, I., and Losson, R. (2011) Proc. Natl. Acad. Sci. U.S.A. 108, 8212-8217
19. Desmet, V. J. (2009) Hepatology 49, 355-357
20. Khetchoumian, K., Teletin, M., Mark, M., Lerouge, T., Cerviño, M., Oulad-Abdelghani, M., Chambon, P., and Losson, R. (2004) J. Biol. Chem. 279, 48329-48341
21. Wu, J. C., Merlino, G., and Fausto, N. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 674-678
22. Kolla, V., Weihua, X., and Kalvakolanu, D. V. (1997) J. Biol. Chem. 272, 9742-9748
23. Loudig, O., Babichuk, C., White, J., Abu-Abed, S., Mueller, C., and Petkovich, M. (2000) Mol. Endocrinol. 14, 1483-1497
24. Platanias, L. C. (2005) Nat. Rev. Immunol. 5, 375-386
25. Samarajiwa, S. A., Forster, S., Auchettl, K., and Hertzog, P. J. (2009) Nucleic Acids Res. 37, D852-D857
26. Taniguchi, T., Ogasawara, K., Takaoka, A., and Tanaka, N. (2001) Annu. Rev. Immunol. 19, 623-655
27. Sherr, C. J., and Roberts, J. M. (1999) Genes Dev. 13, 1501-1512
28. Resar, L. M., Dolde, C., Barrett, J. F., and Dang, C. V. (1993) Mol. Cell Biol. 13, 1130-1136
29. Lehner, F., Kulik, U., Klempnauer, J., and Borlak, J. (2007) FASEB J. 21, 1445-1462
30. Lehner, F., Kulik, U., Klempnauer, J., and Borlak, J. (2010) PLoS One 5, e13344
31. Wu, H., Wade, M., Krall, L., Grisham, J., Xiong, Y., and Van Dyke, T. (1996) Genes Dev. 10, 245-260
32. Gupta, S. (2000) Semin. Cancer Biol. 10, 161-171
33. Balmer, J. E., and Blomhoff, R. (2002) J. Lipid Res. 43, 1773-1808
34. Sarasin-Filipowicz, M., Wang, X., Yan, M., Duong, F. H., Poli, V., Hilton, D. J., Zhang, D. E., and Heim, M. H. (2009) Mol. Cell. Biol. 29, 4841-4851
35. Krebs, D. L., and Hilton, D. J. (2001) Stem Cells 19, 378-387
36. Liu, B., Liao, J., Rao, X., Kushner, S. A., Chung, C. D., Chang, D. D., and Shuai, K. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 10626-10631
37. Duong, F. H., Christen, V., Berke, J. M., Penna, S. H., Moradpour, D., and Heim, M. H., (2005) J. Virol. 79, 15342-15350
38. Breuhahn, K., Vreden, S., Haddad, R., Beckebaum, S., Stippel, D., Flemming, P., Nussbaum, T., Caselmann, W. H., Haab, B. B., and Schirmacher, P. (2004) Cancer Res. 64, 6058-6064
39. Kolla, V., Lindner, D. J., Xiao, W., Borden, E. C., and Kalvakolanu, D. V. (1996) J. Biol. Chem. 271, 10508-10514
40. Onitsuka, A., Yamada, N., Yasuda, H., Miyata, T., and Kachi, T. (1996) Surg. Today 26, 126-130
41. Bromberg, J. (2002) J. Clin. Investig. 109, 1139-1142
42. Buettner, R., Mora, L. B., and Jove, R. (2002) Clin. Cancer Res. 8, 945-954
43. Yoshimura, A. (2006) Cancer Sci. 97, 439-447
44. Hanada, T., Kobayashi, T., Chinen, T., Saeki, K., Takaki, H., Koga, K., Minoda, Y., Sanada, T., Yoshioka, T., Mimata, H., Kato, S., and Yoshimura, A. (2006) J. Exp. Med. 203, 1391-1397
45. Ernst, M., Najdovska, M., Grail, D., Lundgren-May, T., Buchert, M., Tye, H., Matthews, V. B., Armes, J., Bhathal, P. S., Hughes, N. R., Marcusson, E. G., Karras, J. G., Na, S., Sedgwick, J. D., Hertzog, P. J., and Jenkins, B. J. (2008) J. Clin. Investig. 118, 1727-1738
46. Lukasiak, S., Schiller, C., Oehlschlaeger, P., Schmidtke, G., Krause, P., Legler, D. F., Autschbach, F., Schirmacher, P., Breuhahn, K., and Groettrup, M. (2008) Oncogene 27, 6068-6074
47. Yoshikawa, H., Matsubara, K., Qian, G. S., Jackson, P., Groopman, J. D., Manning, J. E., Harris, C. C., and Herman, J. G. (2001) Nat. Genet. 28, 29-35
48. Matsuda, M., Nakamoto, Y., Suzuki, S., Kurata, T., and Kaneko, S. (2005) Lab. Invest. 85, 655-663
49. Roberts, D., Schick, J., Conway, S., Biade, S., Laub, P. B., Stevenson, J. P., Hamilton, T. C., O'Dwyer, P. J., and Johnson, S. W. (2005) Br. J. Cancer 92, 1149-1158
50. Khodarev, N. N., Roach, P., Pitroda, S. P., Golden, D. W., Bhayani, M., Shao, M. Y., Darga, T. E., Beveridge, M. G., Sood, R. F., Sutton, H. G., Beckett, M. A., Mauceri, H. J., Posner, M. C., and Weichselbaum, R. R. (2009) PLoS One 4, e5821
51. Chen, L., Li, S., and McGilvray, I. (2011) Int. J. Biochem. Cell Biol., in press
52. Potu, H., Sgorbissa, A., and Brancolini, C. (2010) Cancer Res. 70, 655-665
53. Duex, J. E., Comeau, L., Sorkin, A., Purow, B., and Kefas, B. (2011) J. Biol. Chem. 286, 25377-25386
54. Meraz, M. A., White, J. M., Sheehan, K. C., Bach, E. A., Rodig, S. J., Dighe, A. S., Kaplan, D. H., Riley, J. K., Greenlund, A. C., Campbell, D., Carver-Moore, K., DuBois, R. N., Clark, R., Aguet, M., and Schreiber, R. D. (1996) Cell 84, 431-442
55. Sugawara, I., Yamada, H., and Mizuno, S. (2004) Tohoku J. Exp. Med. 202, 41-50
56. Grivennikov, S. I., Greten, F. R., and Karin, M. (2010) Cell 140, 883-899