Rapid growth of hepatocellular carcinoma after or during interferon treatment for chronic hepatitis C: Report of three cases

Surgery Today

Volumn 26, Issue 2, 1996, Pages 126-130

  Onitsuka, Atsuyoshi ^a   Yamada, Naoki ^b   Yasuda, Hiroyuki ^b   Miyata, Tomoyuki ^b   Kachi, Toshimi ^b  

^a GIFU UNIVERSITY   (Japan)

^b Department of Surgery   (Japan)

Author keywords

hepatocellular carcinoma; interferon

Indexed keywords

ALPHA FETOPROTEIN; ALPHA2B INTERFERON; INTERFERON;

ADULT; AGED; ARTICLE; ARTIFICIAL EMBOLISM; CANCER GROWTH; CASE REPORT; CHRONIC HEPATITIS; HEPATITIS C; HUMAN; IMMUNOTHERAPY; LIVER CELL CARCINOMA; MALE; PARTIAL HEPATECTOMY;

ADULT; AGED; ANTIVIRAL AGENTS; CARCINOMA, HEPATOCELLULAR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FOLLOW-UP STUDIES; HEPATECTOMY; HEPATITIS C; HEPATITIS, CHRONIC; HUMANS; INTERFERON ALFA-2B; LIVER NEOPLASMS; MALE; MIDDLE AGED; TOMOGRAPHY, X-RAY COMPUTED;

EID: 0029870548     PISSN: 09411291     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00311777     Document Type: Article

References (16)

1. Choo Q-L, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M (1989) Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 244: 359-362
2. Yano M, Yatsuhashi H, Inoue O, Inokuchi K, Koga M (1993) Epidemiology and long term prognosis of hepatitis C virus infection in Japan. Gut 34:S13-S16
3. Onitsuka A, Yasuda H, Yamada N, Miyata T, Kachi T (1994) A case of ruptured hepatocellular carcinoma with rapid growth after interferon therapy in chronic hepatitis (in Japanese with English abstract). Nippon Geka Gakkai Zasshi (J Jpn Surg Soc) 95:838-842
4. Yoshida T, Okazaki N, Yoshino M, Kitaoka H, Hirohashi S, Shimozato Y (1982) Minute hepatocellular carcinoma without appreciable change in size for seven years: A case report. Cancer 49:1491-1495
5. Sheu JC, Sung JL, Chen DS, Yang PM, Lai MY, Lee CS, Hsu HC, Chuang CN, Yang PC, Wang TH, Lin JT, Lee CZ (1985) Growth rate of a symptomatic hepatocellular carcinoma and its clinical implication. Gastroenterology 89:258-266
6. Davidson AR, Tomlinson S, Calne RY, Williams R (1974) The variable course of primary hepatocellular carcinoma. Br J Surg 61:349-352
7. Lam KG, Ho JCI, Yeung RTT (1982) Spontaneous regression of hepatocellular carcinoma. Cancer 50:332-36
8. Ebara M, Ohto M, Shinagawa T, Sugiura N, Kimura K, Matsutani S, Morita M, Saisho H, Tsuchiya Y, Okuda K (1986) Natural history of minute hepatocellular carcinoma smaller than three centimeters complicating cirrhosis - a study in 22 patients. Gastroenterology 90:289-298
9. Okazaki N, Yoshino M, Yoshida T, Suzuki M, Moriyama N, Takayasu K, Makuuchi M, Yamazaki S, Hasegawa H, Noguchi M, Hirohashi S (1989) Evaluation of the prognosis for small hepatocellular carcinoma based on tumor volume doubling time - a preliminary report. Cancer 63:2207-2210
10. Chakraborty PR, Ruiz-Opazo N, Shouval D, Shafritz DA (1980) Identification of integrated hepatitis B virus DNA and expression of viral RNA in an HBsAg-producing human hepatocellular carcinoma cell line. Nature 286:531-533
11. The Gastrointestinal Tumor Group (1990) A prospective trial of recombinant human interferon alpha 2B in previously untreated patients with hepatocellular carcinoma. Cancer 66:135-139
12. Sachs E, Di Bisceglie AM, Dusheiko GM, Song E, Lyons SF, Schoub BD, Kew MC (1985) Treatment of hepatocellular carcinoma with recombinant leucocyte interferon: A pilot study. Br J Cancer 52:105-109
13. Forbes A, Johnson PJ, Williams R (1985) Recombinant human gamma-interferon in primary hepatocellular carcinoma. J R Soc Med 78:826-829
14. Gresser I, Maury C, Brouty-Boye D (1972) Mechanisms of the antitumor effect of interferon in mice. Nature 239:167-168
15. Durum SK, Oppenheim JJ (1989) Macrophage-derived mediators: interleukin-1, tumor necrosis factor, interleukin-6, interferon, and related cytokines. In: Paul W (ed) Fundamental immunology. Raven, New York, pp 639-661
16. Inagaki Y, Unoura M, Kobayashi K (1992) Clinical features and diagnosis of primary liver cancer. In: Tobe T (ed) Primary liver cancer in Japan. Springer, Berlin Heidelberg New York Tokyo, pp 93-102