Expression of an Mg2+-dependent HIV-1 RNase H construct for drug screening

Antimicrobial Agents and Chemotherapy

Volumn 55, Issue 10, 2011, Pages 4735-4741

  Farias, Richard V ^b,c   Vargas, Deborah A ^a   Castillo, Andres E ^a   Valenzuela, Beatriz ^a,d   Coté, Marie L ^b,e   Roth, Monica J ^b   Leon, Oscar ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^c RUTGERS UNIVERSITY   (United States)

^d UNIVERSIDAD DE SANTIAGO DE CHILE   (Chile)

^e WILLIAM PATERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAGNESIUM ION; PROTEIN P51; PROTEIN P66; RIBONUCLEASE H; RNA DIRECTED DNA POLYMERASE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; MAGNESIUM; REVERSE TRANSCRIPTASE, HUMAN IMMUNODEFICIENCY VIRUS 1; RNA DIRECTED DNA POLYMERASE INHIBITOR; TRANSFER RNA;

ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; DRUG SCREENING; ESCHERICHIA COLI; FLUORESCENCE; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR MODEL; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN INDUCTION; PROTEIN PURIFICATION; WILD TYPE; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; ANTI-HIV AGENTS; BASE SEQUENCE; DRUG EVALUATION, PRECLINICAL; HIV REVERSE TRANSCRIPTASE; HIV-1; MAGNESIUM; MODELS, MOLECULAR; REVERSE TRANSCRIPTASE INHIBITORS; RIBONUCLEASE H; RNA, TRANSFER; SEQUENCE ANALYSIS, RNA;

EID: 80052839917     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00658-11     Document Type: Article

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