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Volumn 5, Issue 1, 2000, Pages 67-74
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Metal-ion stoichiometry of the HIV-1 RT ribonuclease H domain: Evidence for two mutually exclusive sites leads to new mechanistic insights on metal- mediated hydrolysis in nucleic acid biochemistry
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Author keywords
Calorimetry; Human immunodeficiency virus type 1 reverse transcriptase ribonuclease H domain; Mechanism; Metal binding; Stoichiometry
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Indexed keywords
DIVALENT CATION;
MAGNESIUM ION;
MANGANESE;
RIBONUCLEASE H;
RNA DIRECTED DNA POLYMERASE;
ARTICLE;
CONTROLLED STUDY;
ENZYME ACTIVE SITE;
ENZYME BINDING;
ENZYME CONFORMATION;
HUMAN IMMUNODEFICIENCY VIRUS 1;
HYDROLYSIS;
METAL BINDING;
NONHUMAN;
NUCLEIC ACID METABOLISM;
PRIORITY JOURNAL;
PROTEIN DOMAIN;
REACTION ANALYSIS;
STOICHIOMETRY;
STRUCTURE ACTIVITY RELATION;
STRUCTURE ANALYSIS;
ESCHERICHIA COLI;
HUMAN IMMUNODEFICIENCY VIRUS;
HUMAN IMMUNODEFICIENCY VIRUS 1;
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EID: 0034002794
PISSN: 09498257
EISSN: None
Source Type: Journal
DOI: 10.1007/s007750050009 Document Type: Article |
Times cited : (50)
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References (39)
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