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Volumn 119, Issue 10, 2011, Pages 651-662

Drosophila phagocytosis - still many unknowns under the surface

Author keywords

Drosophila; Host microbe interaction; Phagocytosis; RNAi

Indexed keywords

ADAPTIVE IMMUNITY; CELLULAR IMMUNITY; DROSOPHILA MELANOGASTER; HOST RESISTANCE; HUMAN; IN VITRO STUDY; INNATE IMMUNITY; MACROPHAGE; MAMMAL; MOLECULAR RECOGNITION; NONHUMAN; PHAGOCYTOSIS; PLASMA CELL; PRIORITY JOURNAL; REVIEW; RNA INTERFERENCE;

EID: 80052823818     PISSN: 09034641     EISSN: 16000463     Source Type: Journal    
DOI: 10.1111/j.1600-0463.2011.02792.x     Document Type: Review
Times cited : (51)

References (84)
  • 2
    • 34047268684 scopus 로고    scopus 로고
    • The host defense of Drosophila melanogaster
    • Lemaitre B, Hoffmann J. The host defense of Drosophila melanogaster. Annu Rev Immunol 2007;25:697-743.
    • (2007) Annu Rev Immunol , vol.25 , pp. 697-743
    • Lemaitre, B.1    Hoffmann, J.2
  • 3
    • 79251557500 scopus 로고    scopus 로고
    • The Drosophila Toll signaling pathway
    • Valanne S, Wang JH, Rämet M. The Drosophila Toll signaling pathway. J Immunol 2011;186:649-56.
    • (2011) J Immunol , vol.186 , pp. 649-656
    • Valanne, S.1    Wang, J.H.2    Rämet, M.3
  • 4
    • 77449152273 scopus 로고    scopus 로고
    • RNA silencing in the antiviral innate immune defence - role of DEAD-box RNA helicases
    • Ulvila J, Hultmark D, Rämet M. RNA silencing in the antiviral innate immune defence - role of DEAD-box RNA helicases. Scand J Immunol 2010;71:146-58.
    • (2010) Scand J Immunol , vol.71 , pp. 146-158
    • Ulvila, J.1    Hultmark, D.2    Rämet, M.3
  • 5
    • 79955597885 scopus 로고    scopus 로고
    • Drosophila as a model for antiviral immunity
    • Wang JH, Valanne S, Rämet M. Drosophila as a model for antiviral immunity. World J Biol Chem 2010;1:151-9.
    • (2010) World J Biol Chem , vol.1 , pp. 151-159
    • Wang, J.H.1    Valanne, S.2    Rämet, M.3
  • 6
    • 0033638404 scopus 로고    scopus 로고
    • Tissue-specific inducible expression of antimicrobial peptide genes in Drosophila surface epithelia
    • Tzou P, Ohresser S, Ferrandon D, Capovilla M, Reichhart JM, Lemaitre B, et al. Tissue-specific inducible expression of antimicrobial peptide genes in Drosophila surface epithelia. Immunity 2000;13:737-48.
    • (2000) Immunity , vol.13 , pp. 737-748
    • Tzou, P.1    Ohresser, S.2    Ferrandon, D.3    Capovilla, M.4    Reichhart, J.M.5    Lemaitre, B.6
  • 7
    • 0036149337 scopus 로고    scopus 로고
    • JNK signalling pathway is required for efficient wound healing in Drosophila
    • Rämet M, Lanot R, Zachary D, Manfruelli P. JNK signalling pathway is required for efficient wound healing in Drosophila. Dev Biol 2002;241:145-56.
    • (2002) Dev Biol , vol.241 , pp. 145-156
    • Rämet, M.1    Lanot, R.2    Zachary, D.3    Manfruelli, P.4
  • 8
    • 19344365657 scopus 로고    scopus 로고
    • Cellular and genetic analysis of wound healing in Drosophila larvae
    • Galko MJ, Krasnow MA. Cellular and genetic analysis of wound healing in Drosophila larvae. PLoS Biol 2004;2:e239.
    • (2004) PLoS Biol , vol.2
    • Galko, M.J.1    Krasnow, M.A.2
  • 9
    • 0032005367 scopus 로고    scopus 로고
    • Role of prophenoloxidase-activating system in invertebrate immunity
    • Söderhäll K, Cerenius L. Role of prophenoloxidase-activating system in invertebrate immunity. Curr Opin Immunol 1998;10:23-8.
    • (1998) Curr Opin Immunol , vol.10 , pp. 23-28
    • Söderhäll, K.1    Cerenius, L.2
  • 10
    • 34250711204 scopus 로고    scopus 로고
    • A multilayered defense against infection: combinatorial control of insect immune genes
    • Uvell H, Engström Y. A multilayered defense against infection: combinatorial control of insect immune genes. Trends Genet 2007;23:342-9.
    • (2007) Trends Genet , vol.23 , pp. 342-349
    • Uvell, H.1    Engström, Y.2
  • 11
    • 0032473360 scopus 로고    scopus 로고
    • A Drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway
    • Ferrandon D, Jung AC, Criqui M, Lemaitre B, Uttenweiler-Joseph S, Michaut L, et al. A Drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway. EMBO J 1998;17:1217-27.
    • (1998) EMBO J , vol.17 , pp. 1217-1227
    • Ferrandon, D.1    Jung, A.C.2    Criqui, M.3    Lemaitre, B.4    Uttenweiler-Joseph, S.5    Michaut, L.6
  • 12
    • 0035065782 scopus 로고    scopus 로고
    • The Imd gene is required for local Cecropin expression in Drosophila barrier epithelia
    • Önfelt Tingvall T, Roos E, Engstrom Y. The Imd gene is required for local Cecropin expression in Drosophila barrier epithelia. EMBO Rep 2001;2:239-43.
    • (2001) EMBO Rep , vol.2 , pp. 239-243
    • Önfelt Tingvall, T.1    Roos, E.2    Engstrom, Y.3
  • 13
    • 10744230355 scopus 로고    scopus 로고
    • The homeobox gene Caudal regulates constitutive local expression of antimicrobial peptide genes in Drosophila epithelia
    • Ryu JH, Nam KB, Oh CT, Nam HJ, Kim SH, Yoon JH, et al. The homeobox gene Caudal regulates constitutive local expression of antimicrobial peptide genes in Drosophila epithelia. Mol Cell Biol 2004;24:172-85.
    • (2004) Mol Cell Biol , vol.24 , pp. 172-185
    • Ryu, J.H.1    Nam, K.B.2    Oh, C.T.3    Nam, H.J.4    Kim, S.H.5    Yoon, J.H.6
  • 14
    • 0030595339 scopus 로고    scopus 로고
    • The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults
    • Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA. The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 1996;86:973-83.
    • (1996) Cell , vol.86 , pp. 973-983
    • Lemaitre, B.1    Nicolas, E.2    Michaut, L.3    Reichhart, J.M.4    Hoffmann, J.A.5
  • 15
    • 0035940514 scopus 로고    scopus 로고
    • Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays
    • De Gregorio E, Spellman PT, Rubin GM, Lemaitre B. Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays. Proc Natl Acad Sci USA 2001;98:12590-5.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 12590-12595
    • De Gregorio, E.1    Spellman, P.T.2    Rubin, G.M.3    Lemaitre, B.4
  • 17
    • 0036848010 scopus 로고    scopus 로고
    • Sequential activation of signalling pathways during innate immune responses in Drosophila
    • Boutros M, Agaisse H, Perrimon N. Sequential activation of signalling pathways during innate immune responses in Drosophila. Dev Cell 2002;3:711-22.
    • (2002) Dev Cell , vol.3 , pp. 711-722
    • Boutros, M.1    Agaisse, H.2    Perrimon, N.3
  • 18
    • 0037061482 scopus 로고    scopus 로고
    • Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli
    • Rämet M, Manfruelli P, Pearson A, Mathey-Prevot B, Ezokowitz RA. Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli. Nature 2002;416:644-8.
    • (2002) Nature , vol.416 , pp. 644-648
    • Rämet, M.1    Manfruelli, P.2    Pearson, A.3    Mathey-Prevot, B.4    Ezokowitz, R.A.5
  • 19
    • 0042697323 scopus 로고    scopus 로고
    • Signalling role of hemocytes in Drosophila Jak/STAT-dependent response to septic injury
    • Agaisse H, Petersen UM, Boutros M, Mathey-Prevot B, Perrimon N. Signalling role of hemocytes in Drosophila Jak/STAT-dependent response to septic injury. Dev Cell 2003;5:441-50.
    • (2003) Dev Cell , vol.5 , pp. 441-450
    • Agaisse, H.1    Petersen, U.M.2    Boutros, M.3    Mathey-Prevot, B.4    Perrimon, N.5
  • 21
    • 1842800034 scopus 로고    scopus 로고
    • Proteomic analysis of the systemic immune response of Drosophila
    • Levy F, Bulet P, Ehret-Sabatier L. Proteomic analysis of the systemic immune response of Drosophila. Mol Cell Proteomics 2004;3:156-66.
    • (2004) Mol Cell Proteomics , vol.3 , pp. 156-166
    • Levy, F.1    Bulet, P.2    Ehret-Sabatier, L.3
  • 23
    • 0347635519 scopus 로고    scopus 로고
    • A proteomic approach for the analysis of instantly released wound and immune proteins in Drosophila melanogaster hemolymph
    • Vierstraete E, Verleyen P, Baggerman G, D'Hertog W, Van den Bergh G, Arckens L, et al. A proteomic approach for the analysis of instantly released wound and immune proteins in Drosophila melanogaster hemolymph. Proc Natl Acad Sci USA 2004;101:470-5.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 470-475
    • Vierstraete, E.1    Verleyen, P.2    Baggerman, G.3    D'Hertog, W.4    Van den Bergh, G.5    Arckens, L.6
  • 24
    • 20444506693 scopus 로고    scopus 로고
    • Functional analysis of immune response genes in Drosophila identifies JNK pathway as a regulator of antimicrobial peptide gene expression in S2 cells
    • Kallio J, Leinonen A, Ulvila J, Valanne S, Ezekowitz RAB, Rämet M. Functional analysis of immune response genes in Drosophila identifies JNK pathway as a regulator of antimicrobial peptide gene expression in S2 cells. Microbes Infect 2005;7:811-9.
    • (2005) Microbes Infect , vol.7 , pp. 811-819
    • Kallio, J.1    Leinonen, A.2    Ulvila, J.3    Valanne, S.4    Ezekowitz, R.A.B.5    Rämet, M.6
  • 26
    • 34247103287 scopus 로고    scopus 로고
    • Drosophila hemopoiesis and cellular immunity
    • Williams MJ. Drosophila hemopoiesis and cellular immunity. J Immunol 2007;178:4711-6.
    • (2007) J Immunol , vol.178 , pp. 4711-4716
    • Williams, M.J.1
  • 28
    • 0034126807 scopus 로고    scopus 로고
    • Developmental patterning genes and their conserved functions: from model organisms to humans
    • Veraksa A, Del Campo M, McGinnis W. Developmental patterning genes and their conserved functions: from model organisms to humans. Mol Genet Metab 2000;69:85-100.
    • (2000) Mol Genet Metab , vol.69 , pp. 85-100
    • Veraksa, A.1    Del Campo, M.2    McGinnis, W.3
  • 29
    • 0034837386 scopus 로고    scopus 로고
    • A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster
    • Reiter LT, Potocki L, Chien S, Gribskov M, Bier E. A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster. Genome Res 2001;11:1114-25.
    • (2001) Genome Res , vol.11 , pp. 1114-1125
    • Reiter, L.T.1    Potocki, L.2    Chien, S.3    Gribskov, M.4    Bier, E.5
  • 30
    • 0037330695 scopus 로고    scopus 로고
    • Modelling human diseases in Drosophila and Caenorhabditis
    • O'Kane CJ. Modelling human diseases in Drosophila and Caenorhabditis. Semin Cell Dev Biol 2002;14:3-10.
    • (2002) Semin Cell Dev Biol , vol.14 , pp. 3-10
    • O'Kane, C.J.1
  • 31
    • 10644276290 scopus 로고    scopus 로고
    • Drosophila, the golden bug, emerges as a tool for human genetics
    • Bier E. Drosophila, the golden bug, emerges as a tool for human genetics. Nat Rev Genet 2005;6:9-23.
    • (2005) Nat Rev Genet , vol.6 , pp. 9-23
    • Bier, E.1
  • 32
    • 0015328565 scopus 로고
    • Cell lines derived from late embryonic stages of Drosophila melanogaster
    • Schneider I. Cell lines derived from late embryonic stages of Drosophila melanogaster. Embryol Exp Morphol 1972;27:353-65.
    • (1972) Embryol Exp Morphol , vol.27 , pp. 353-365
    • Schneider, I.1
  • 33
    • 0018099247 scopus 로고
    • Malignant neoplasms of genetic origin in Drosophila melanogaster
    • Gateff E. Malignant neoplasms of genetic origin in Drosophila melanogaster. Science 1978;200:1448-59.
    • (1978) Science , vol.200 , pp. 1448-1459
    • Gateff, E.1
  • 34
    • 0035690765 scopus 로고    scopus 로고
    • Drosophila scavenger receptor CI is a pattern recognition receptor for bacteria
    • Rämet M, Pearson A, Manfruelli P, Li X, Koziel H, Göbel V, et al. Drosophila scavenger receptor CI is a pattern recognition receptor for bacteria. Immunity 2001;15:1027-38.
    • (2001) Immunity , vol.15 , pp. 1027-1038
    • Rämet, M.1    Pearson, A.2    Manfruelli, P.3    Li, X.4    Koziel, H.5    Göbel, V.6
  • 35
    • 0042564535 scopus 로고    scopus 로고
    • Identification of cytoskeletal regulatory proteins required for efficient phagocytosis in Drosophila
    • Pearson AM, Baksa K, Rämet M, Protas M, McKee M, Brown D, et al. Identification of cytoskeletal regulatory proteins required for efficient phagocytosis in Drosophila. Microbes Infect 2003;5:815-24.
    • (2003) Microbes Infect , vol.5 , pp. 815-824
    • Pearson, A.M.1    Baksa, K.2    Rämet, M.3    Protas, M.4    McKee, M.5    Brown, D.6
  • 36
    • 26844466658 scopus 로고    scopus 로고
    • Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila
    • Kocks C, Cho JH, Nehme N, Ulvila J, Pearson AM, Meister M, et al. Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila. Cell 2005;123:335-46.
    • (2005) Cell , vol.123 , pp. 335-346
    • Kocks, C.1    Cho, J.H.2    Nehme, N.3    Ulvila, J.4    Pearson, A.M.5    Meister, M.6
  • 37
    • 0027160708 scopus 로고
    • Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
    • Brand AH, Perrimon N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 1993;118:401-15.
    • (1993) Development , vol.118 , pp. 401-415
    • Brand, A.H.1    Perrimon, N.2
  • 38
    • 34447530305 scopus 로고    scopus 로고
    • A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila
    • Dietzl G, Chen D, Schnorrer F, Su KC, Barinova Y, Fellner M, et al. A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila. Nature 2007;448:151-6.
    • (2007) Nature , vol.448 , pp. 151-156
    • Dietzl, G.1    Chen, D.2    Schnorrer, F.3    Su, K.C.4    Barinova, Y.5    Fellner, M.6
  • 39
    • 0031251977 scopus 로고    scopus 로고
    • Treatment of l(2)mbn Drosophila tumorous blood cells with the steroid hormone ecdysone amplifies the inducibility of antimicrobial peptide gene expression
    • Dimarcq JL, Imler JL, Lanot R, Ezekowitz RA, Hoffmann JA, Janeway CA, et al. Treatment of l(2)mbn Drosophila tumorous blood cells with the steroid hormone ecdysone amplifies the inducibility of antimicrobial peptide gene expression. Insect Biochem Mol Biol 1997;27:877-86.
    • (1997) Insect Biochem Mol Biol , vol.27 , pp. 877-886
    • Dimarcq, J.L.1    Imler, J.L.2    Lanot, R.3    Ezekowitz, R.A.4    Hoffmann, J.A.5    Janeway, C.A.6
  • 40
    • 19344363325 scopus 로고    scopus 로고
    • Phagocytosis: elegant complexity
    • Stuart LM, Ezekowitz RA. Phagocytosis: elegant complexity. Immunity 2005;22:539-50.
    • (2005) Immunity , vol.22 , pp. 539-550
    • Stuart, L.M.1    Ezekowitz, R.A.2
  • 41
    • 0033046220 scopus 로고    scopus 로고
    • Mechanisms of phagocytosis in macrophages
    • Aderem A, Underhill DM. Mechanisms of phagocytosis in macrophages. Annu Rev Immunol 1999;17:593-623.
    • (1999) Annu Rev Immunol , vol.17 , pp. 593-623
    • Aderem, A.1    Underhill, D.M.2
  • 42
    • 46449093431 scopus 로고    scopus 로고
    • Molecular mechanisms of phagocytic uptake in mammalian cells
    • Groves E, Dart AE, Covarelli V, Caron E. Molecular mechanisms of phagocytic uptake in mammalian cells. Cell Mol Life Sci 2008;65:1957-76.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 1957-1976
    • Groves, E.1    Dart, A.E.2    Covarelli, V.3    Caron, E.4
  • 43
    • 23844531867 scopus 로고    scopus 로고
    • Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection
    • Philips JA, Rubin EJ, Perrimon N. Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection. Science 2005;309:1251-3.
    • (2005) Science , vol.309 , pp. 1251-1253
    • Philips, J.A.1    Rubin, E.J.2    Perrimon, N.3
  • 44
    • 23744514918 scopus 로고    scopus 로고
    • Response to Staphylococcus aureus requires CD36-mediated phagocytosis triggered by the COOH-terminal cytoplasmic domain
    • Stuart LM, Deng J, Silver JM, Takahashi K, Tseng AA, Hennessy EJ, et al. Response to Staphylococcus aureus requires CD36-mediated phagocytosis triggered by the COOH-terminal cytoplasmic domain. J Cell Biol 2005;170:477-85.
    • (2005) J Cell Biol , vol.170 , pp. 477-485
    • Stuart, L.M.1    Deng, J.2    Silver, J.M.3    Takahashi, K.4    Tseng, A.A.5    Hennessy, E.J.6
  • 47
    • 23844442475 scopus 로고    scopus 로고
    • Genome-wide RNAi screen for host factors required for intracellular bacterial infection
    • Agaisse H, Burrack LS, Philips JA, Rubin EJ, Perrimon N, Higgins DE. Genome-wide RNAi screen for host factors required for intracellular bacterial infection. Science 2005;309:1248-51.
    • (2005) Science , vol.309 , pp. 1248-1251
    • Agaisse, H.1    Burrack, L.S.2    Philips, J.A.3    Rubin, E.J.4    Perrimon, N.5    Higgins, D.E.6
  • 48
    • 0037061450 scopus 로고    scopus 로고
    • The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein
    • Gottar M, Gobert V, Michel T, Belvin M, Duyk G, Hoffmann JA, et al. The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein. Nature 2002;416:640-4.
    • (2002) Nature , vol.416 , pp. 640-644
    • Gottar, M.1    Gobert, V.2    Michel, T.3    Belvin, M.4    Duyk, G.5    Hoffmann, J.A.6
  • 49
    • 0037066464 scopus 로고    scopus 로고
    • Requirement for a peptidoglycan recognition protein (PGRP) in Relish activation and antibacterial immune responses in Drosophila
    • Choe KM, Werner T, Stöven S, Hultmark D, Anderson KV. Requirement for a peptidoglycan recognition protein (PGRP) in Relish activation and antibacterial immune responses in Drosophila. Science 2002;296:359-62.
    • (2002) Science , vol.296 , pp. 359-362
    • Choe, K.M.1    Werner, T.2    Stöven, S.3    Hultmark, D.4    Anderson, K.V.5
  • 50
    • 0034633786 scopus 로고    scopus 로고
    • Constitutive expression of a complement-like protein in Toll and JAK gain-of-function mutants of Drosophila
    • Lagueux M, Perrodou E, Levashina EA, Capovilla M, Hoffmann JA. Constitutive expression of a complement-like protein in Toll and JAK gain-of-function mutants of Drosophila. Proc Natl Acad Sci USA 2000;97:11427-32.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 11427-11432
    • Lagueux, M.1    Perrodou, E.2    Levashina, E.A.3    Capovilla, M.4    Hoffmann, J.A.5
  • 51
    • 1542328964 scopus 로고    scopus 로고
    • Complement-like protein TEP1 is a determinant of vectorial capacity in the malaria vector Anopheles gambiae
    • Blandin S, Shiao SH, Moita LF, Janse CJ, Waters AP, Kafatos FC, et al. Complement-like protein TEP1 is a determinant of vectorial capacity in the malaria vector Anopheles gambiae. Cell 2004;116:661-70.
    • (2004) Cell , vol.116 , pp. 661-670
    • Blandin, S.1    Shiao, S.H.2    Moita, L.F.3    Janse, C.J.4    Waters, A.P.5    Kafatos, F.C.6
  • 52
    • 31144437860 scopus 로고    scopus 로고
    • Identification of Drosophila gene products required for phagocytosis of Candida albicans
    • Stroschein-Stevenson SL, Foley E, O'Farrell PH, Johnson AD. Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol 2006;4:e4.
    • (2006) PLoS Biol , vol.4
    • Stroschein-Stevenson, S.L.1    Foley, E.2    O'Farrell, P.H.3    Johnson, A.D.4
  • 53
    • 77953788083 scopus 로고    scopus 로고
    • Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters
    • Charrière GM, Ip WE, Dejardin S, Boyer L, Sokolovska A, Cappillino MP, et al. Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters. J Biol Chem. 2010;285:20147-54.
    • (2010) J Biol Chem. , vol.285 , pp. 20147-20154
    • Charrière, G.M.1    Ip, W.E.2    Dejardin, S.3    Boyer, L.4    Sokolovska, A.5    Cappillino, M.P.6
  • 54
  • 55
    • 0034625260 scopus 로고    scopus 로고
    • Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity
    • Schmucker D, Clemens JC, Shu H, Worby CA, Xiao J, Muda M, et al. Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity. Cell 2000;101:671-84.
    • (2000) Cell , vol.101 , pp. 671-684
    • Schmucker, D.1    Clemens, J.C.2    Shu, H.3    Worby, C.A.4    Xiao, J.5    Muda, M.6
  • 57
    • 4444318773 scopus 로고    scopus 로고
    • Alternative splicing of Drosophila Dscam generates axon guidance receptors that exhibit isoform-specific homophilic binding
    • Wojtowicz WM, Flanagan JJ, Millard SS, Zipursky SL, Clemens JC. Alternative splicing of Drosophila Dscam generates axon guidance receptors that exhibit isoform-specific homophilic binding. Cell 2004;118:619-33.
    • (2004) Cell , vol.118 , pp. 619-633
    • Wojtowicz, W.M.1    Flanagan, J.J.2    Millard, S.S.3    Zipursky, S.L.4    Clemens, J.C.5
  • 58
    • 33745874084 scopus 로고    scopus 로고
    • AgDscam, a hypervariable immunoglobulin domain-containing receptor of the Anopheles gambiae innate immune system
    • Dong Y, Taylor HE, Dimopoulos G. AgDscam, a hypervariable immunoglobulin domain-containing receptor of the Anopheles gambiae innate immune system. PLoS Biol 2006;4:e229.
    • (2006) PLoS Biol , vol.4
    • Dong, Y.1    Taylor, H.E.2    Dimopoulos, G.3
  • 59
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998;391:806-11.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 60
    • 0034636715 scopus 로고    scopus 로고
    • dsRNA-mediated gene silencing in cultured Drosophila cells: a tissue culture model for the analysis of RNA interference
    • Caplen NJ, Fleenor J, Fire A, Morgan RA. dsRNA-mediated gene silencing in cultured Drosophila cells: a tissue culture model for the analysis of RNA interference. Gene 2000;252:95-105.
    • (2000) Gene , vol.252 , pp. 95-105
    • Caplen, N.J.1    Fleenor, J.2    Fire, A.3    Morgan, R.A.4
  • 62
    • 33744910636 scopus 로고    scopus 로고
    • Double-stranded RNA is internalized by scavenger receptor - mediated endocytosis in Drosophila S2 cells
    • Ulvila J, Parikka M, Kleino A, Sormunen R, Ezekowitz RA, Kocks C, et al. Double-stranded RNA is internalized by scavenger receptor - mediated endocytosis in Drosophila S2 cells. J Biol Chem 2006;281:14370-5.
    • (2006) J Biol Chem , vol.281 , pp. 14370-14375
    • Ulvila, J.1    Parikka, M.2    Kleino, A.3    Sormunen, R.4    Ezekowitz, R.A.5    Kocks, C.6
  • 63
    • 27144475536 scopus 로고    scopus 로고
    • Inhibitor of apoptosis 2 and TAK1 binding protein are components of the Drosophila Imd pathway
    • Kleino A, Valanne S, Ulvila J, Kallio J, Myllymäki H, Enwald H, et al. Inhibitor of apoptosis 2 and TAK1 binding protein are components of the Drosophila Imd pathway. EMBO J 2005;24:3423-34.
    • (2005) EMBO J , vol.24 , pp. 3423-3434
    • Kleino, A.1    Valanne, S.2    Ulvila, J.3    Kallio, J.4    Myllymäki, H.5    Enwald, H.6
  • 64
    • 26444472477 scopus 로고    scopus 로고
    • Use of RNA interference in Drosophila S2 cells to identify host pathways controlling compartmentalization of an intracellular pathogen
    • Cheng LW, Viala JP, Stuurman N, Wiedemann U, Vale RD, Portnoy DA. Use of RNA interference in Drosophila S2 cells to identify host pathways controlling compartmentalization of an intracellular pathogen. Proc Natl Acad Sci USA 2005;102:13646-51.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 13646-13651
    • Cheng, L.W.1    Viala, J.P.2    Stuurman, N.3    Wiedemann, U.4    Vale, R.D.5    Portnoy, D.A.6
  • 65
    • 36048985618 scopus 로고    scopus 로고
    • RNAi screen in Drosophila cells reveals the involvement of the Tom complex in Chlamydia infection
    • Derré I, Pypaert M, Dautry-Varsat A, Agaisse H. RNAi screen in Drosophila cells reveals the involvement of the Tom complex in Chlamydia infection. PLoS Pathog 2007;3:e155.
    • (2007) PLoS Pathog , vol.3
    • Derré, I.1    Pypaert, M.2    Dautry-Varsat, A.3    Agaisse, H.4
  • 67
    • 79955817261 scopus 로고    scopus 로고
    • Cofilin regulator 14-3-3-ζ is an evolutionary conserved protein required for phagocytosis and microbial resistance
    • Ulvila J, Vanha-aho LM, Kleino A, Vähä-Mäkilä M, Vuoksio M, Eskelinen S, et al. Cofilin regulator 14-3-3-ζ is an evolutionary conserved protein required for phagocytosis and microbial resistance. J Leuk Bio 2011;89:649-59.
    • (2011) J Leuk Bio , vol.89 , pp. 649-659
    • Ulvila, J.1    Vanha-aho, L.M.2    Kleino, A.3    Vähä-Mäkilä, M.4    Vuoksio, M.5    Eskelinen, S.6
  • 69
    • 0034724440 scopus 로고    scopus 로고
    • The phytopathogenic bacteria Erwinia carotovora infects Drosophila and activates an immune response
    • Basset A, Khush RS, Braun A, Gardan L, Boccard F, Hoffmann JA, et al. The phytopathogenic bacteria Erwinia carotovora infects Drosophila and activates an immune response. Proc Natl Acad Sci USA 2000;97:3376-81.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3376-3381
    • Basset, A.1    Khush, R.S.2    Braun, A.3    Gardan, L.4    Boccard, F.5    Hoffmann, J.A.6
  • 70
    • 33845877453 scopus 로고    scopus 로고
    • Psidin is required in Drosophila blood cells for both phagocytic degradation and immune activation of the fat body
    • Brennan CA, Delaney JR, Schneider DS, Anderson KV. Psidin is required in Drosophila blood cells for both phagocytic degradation and immune activation of the fat body. Curr Biol 2007;17:67-72.
    • (2007) Curr Biol , vol.17 , pp. 67-72
    • Brennan, C.A.1    Delaney, J.R.2    Schneider, D.S.3    Anderson, K.V.4
  • 71
    • 14044272776 scopus 로고    scopus 로고
    • New insights into Drosophila larval haemocyte functions through genome-wide analysis
    • Irving P, Ubeda JM, Doucet D, Troxler L, Lagueux M, Zachary D, et al. New insights into Drosophila larval haemocyte functions through genome-wide analysis. Cell Microbiol 2005;7:335-50.
    • (2005) Cell Microbiol , vol.7 , pp. 335-350
    • Irving, P.1    Ubeda, J.M.2    Doucet, D.3    Troxler, L.4    Lagueux, M.5    Zachary, D.6
  • 72
    • 67649878194 scopus 로고    scopus 로고
    • Elimination of plasmatocytes by targeted apoptosis reveals their role in multiple aspects of the Drosophila immune response
    • Charroux B, Royet J. Elimination of plasmatocytes by targeted apoptosis reveals their role in multiple aspects of the Drosophila immune response. Proc Natl Acad Sci USA 2009;106:9797-802.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 9797-9802
    • Charroux, B.1    Royet, J.2
  • 73
    • 69949130364 scopus 로고    scopus 로고
    • Genetic ablation of Drosophila phagocytes reveals their contribution to both development and resistance to bacterial infection
    • Defaye A, Evans I, Crozatier M, Wood W, Lemaitre B, Leulier F. Genetic ablation of Drosophila phagocytes reveals their contribution to both development and resistance to bacterial infection. J Innate Immun 2009;1:322-34.
    • (2009) J Innate Immun , vol.1 , pp. 322-334
    • Defaye, A.1    Evans, I.2    Crozatier, M.3    Wood, W.4    Lemaitre, B.5    Leulier, F.6
  • 74
    • 0032564398 scopus 로고    scopus 로고
    • Analysis of the Drosophila host defense in domino mutant larvae, which are devoid of hemocytes
    • Braun A, Hoffmann JA, Meister M. Analysis of the Drosophila host defense in domino mutant larvae, which are devoid of hemocytes. Proc Natl Acad Sci USA 1998;95:14337-42.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 14337-14342
    • Braun, A.1    Hoffmann, J.A.2    Meister, M.3
  • 75
    • 0034729655 scopus 로고    scopus 로고
    • Interactions between the cellular and humoral immune responses in Drosophila
    • Elrod-Erickson M, Mishra S, Schneider D. Interactions between the cellular and humoral immune responses in Drosophila. Curr Biol 2000;10:781-4.
    • (2000) Curr Biol , vol.10 , pp. 781-784
    • Elrod-Erickson, M.1    Mishra, S.2    Schneider, D.3
  • 77
    • 79952285913 scopus 로고    scopus 로고
    • Relative roles of the cellular and humoral responses in the Drosophila host defense against three gram-positive bacterial infections
    • Nehme NT, Quintin J, Cho JH, Lee J, Lafarge MC, Kocks C, et al. Relative roles of the cellular and humoral responses in the Drosophila host defense against three gram-positive bacterial infections. PLoS One 2011;6:e14743.
    • (2011) PLoS One , vol.6
    • Nehme, N.T.1    Quintin, J.2    Cho, J.H.3    Lee, J.4    Lafarge, M.C.5    Kocks, C.6
  • 78
    • 9144269002 scopus 로고    scopus 로고
    • Draper-mediated and phosphatidylserine-independent phagocytosis of apoptotic cells by Drosophila hemocytes/macrophages
    • Manaka J, Kuraishi T, Shiratsuchi A, Nakai Y, Higashida H, Henson P, et al. Draper-mediated and phosphatidylserine-independent phagocytosis of apoptotic cells by Drosophila hemocytes/macrophages. J Biol Chem 2004;279:48466-76.
    • (2004) J Biol Chem , vol.279 , pp. 48466-48476
    • Manaka, J.1    Kuraishi, T.2    Shiratsuchi, A.3    Nakai, Y.4    Higashida, H.5    Henson, P.6
  • 79
    • 0035846903 scopus 로고    scopus 로고
    • CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans
    • Zhou Z, Hartwieg E, Horvitz HR. CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans. Cell 2001;104:43-56.
    • (2001) Cell , vol.104 , pp. 43-56
    • Zhou, Z.1    Hartwieg, E.2    Horvitz, H.R.3
  • 80
    • 42949139497 scopus 로고    scopus 로고
    • Six-microns-under acts upstream of Draper in the glial phagocytosis of apoptotic neurons
    • Kurant E, Axelrod S, Leaman D, Gaul U. Six-microns-under acts upstream of Draper in the glial phagocytosis of apoptotic neurons. Cell 2008;133:498-509.
    • (2008) Cell , vol.133 , pp. 498-509
    • Kurant, E.1    Axelrod, S.2    Leaman, D.3    Gaul, U.4
  • 81
    • 33746190785 scopus 로고    scopus 로고
    • A novel 40-kDa protein containing six repeats of an epidermal growth factor-like domain functions as a pattern recognition protein for lipopolysaccharide
    • Ju JS, Cho MH, Brade L, Kim JH, Park JW, Ha NC, et al. A novel 40-kDa protein containing six repeats of an epidermal growth factor-like domain functions as a pattern recognition protein for lipopolysaccharide. J Immunol 2006;177:1838-45.
    • (2006) J Immunol , vol.177 , pp. 1838-1845
    • Ju, J.S.1    Cho, M.H.2    Brade, L.3    Kim, J.H.4    Park, J.W.5    Ha, N.C.6
  • 82
    • 54549121474 scopus 로고    scopus 로고
    • Undertaker, a Drosophila junctophilin, links Draper-mediated phagocytosis and calcium homeostasis
    • Cuttell L, Vaughan A, Silva E, Escaron CJ, Lavine M, Goethem EV, et al. Undertaker, a Drosophila junctophilin, links Draper-mediated phagocytosis and calcium homeostasis. Cell 2008;135:524-34.
    • (2008) Cell , vol.135 , pp. 524-534
    • Cuttell, L.1    Vaughan, A.2    Silva, E.3    Escaron, C.J.4    Lavine, M.5    Goethem, E.V.6
  • 83
    • 73349134037 scopus 로고    scopus 로고
    • Identification of lipoteichoic acid as a ligand for draper in the phagocytosis of Staphylococcus aureus by Drosophila hemocytes
    • Hashimoto Y, Tabuchi Y, Sakurai K, Kutsuna M, Kurokawa K, Awasaki T, et al. Identification of lipoteichoic acid as a ligand for draper in the phagocytosis of Staphylococcus aureus by Drosophila hemocytes. J Immunol 2009;183:7451-60.
    • (2009) J Immunol , vol.183 , pp. 7451-7460
    • Hashimoto, Y.1    Tabuchi, Y.2    Sakurai, K.3    Kutsuna, M.4    Kurokawa, K.5    Awasaki, T.6
  • 84
    • 21844475827 scopus 로고    scopus 로고
    • In vivo identification of novel regulators and conserved pathways of phagocytosis in A. gambiae
    • Moita LF, Wang-Sattler R, Michel K, Zimmermann T, Blandin S, Levashina EA, et al. In vivo identification of novel regulators and conserved pathways of phagocytosis in A. gambiae. Immunity 2005;23:65-73.
    • (2005) Immunity , vol.23 , pp. 65-73
    • Moita, L.F.1    Wang-Sattler, R.2    Michel, K.3    Zimmermann, T.4    Blandin, S.5    Levashina, E.A.6


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