Human placental lactogen (hPL-A) activates signaling pathways linked to cell survival and improves insulin secretion in human pancreatic islets

Islets

Volumn 3, Issue 5, 2011, Pages 250-258

  Lombardo, Marco F ^a   De Angelis, Fabiana ^a   Bova, Luca ^a   Bartolini, Barbara ^a   Bertuzzi, Federico ^b   Nano, Rita ^b   Capuani, Barbara ^a   Lauro, Renato ^a   Federici, Massimo ^a   Lauro, Davide ^a   Donadel, Giulia ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

cell; Apoptosis; Growth hormone; Islets insulin secretion; Islets survival; PDX 1; Placental lactogen hormone

Indexed keywords

HUMAN PLACENTA LACTOGEN; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PROLACTIN; PROTEIN KINASE B; STAT PROTEIN; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR PDX 1;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; IN VITRO STUDY; INSULIN RELEASE; INSULINOMA; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMAN GROWTH HORMONE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; INSULINOMA; MAP KINASE SIGNALING SYSTEM; MICE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PANCREATIC NEOPLASMS; PLACENTAL LACTOGEN; PROLACTIN; PROTO-ONCOGENE PROTEINS C-AKT; RATS;

EID: 80052773860     PISSN: 19382014     EISSN: 19382022     Source Type: Journal    
DOI: 10.4161/isl.3.5.16900     Document Type: Article

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