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Volumn 10, Issue 9, 2011, Pages

Characterization of human myotubes from type 2 diabetic and nondiabetic subjects using complementary quantitative mass spectrometric methods

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DEAMINASE; GLYCOGEN; INSULIN; METFORMIN; PROLYL DIPEPTIDASE; SULFONYLUREA; TRICHLOROACETIC ACID; DIPEPTIDYL PEPTIDASE IV; DPP4 PROTEIN, HUMAN; GASTRIC INHIBITORY POLYPEPTIDE; GLUCAGON LIKE PEPTIDE 1;

EID: 80052772366     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M110.006650     Document Type: Article
Times cited : (38)

References (65)
  • 1
    • 0031445908 scopus 로고    scopus 로고
    • The rising global burden of diabetes and its complications: Estimates and projections to the year 2010
    • Amos, A. F., McCarty, D. J., and Zimmet, P. (1997) The rising global burden of diabetes and its complications: estimates and projections to the year 2010. Diabet. Med. 14 Suppl 5, S1-85
    • (1997) Diabet. Med. , vol.14 , Issue.SUPPL. 5
    • Amos, A.F.1    McCarty, D.J.2    Zimmet, P.3
  • 2
    • 0031752685 scopus 로고    scopus 로고
    • Global burden of diabetes, 1995-2025: Prevalence, numerical estimates, and projections
    • King, H., Aubert, R. E., and Herman, W. H. (1998) Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care 21, 1414-1431 (Pubitemid 28405191)
    • (1998) Diabetes Care , vol.21 , Issue.9 , pp. 1414-1431
    • King, H.1    Aubert, R.E.2    Herman, W.H.3
  • 3
    • 68849126079 scopus 로고    scopus 로고
    • Obesity, diets, and social inequalities
    • Drewnowski, A. (2009) Obesity, diets, and social inequalities. Nutr. Rev. 67 Suppl 1, S36-9
    • (2009) Nutr. Rev. , vol.67 , Issue.SUPPL. 1
    • Drewnowski, A.1
  • 4
    • 0035856920 scopus 로고    scopus 로고
    • Global and societal implications of the diabetes epidemic
    • DOI 10.1038/414782a
    • Zimmet, P., Alberti, K. G., and Shaw, J. (2001) Global and societal implications of the diabetes epidemic. Nature 414, 782-787 (Pubitemid 34000780)
    • (2001) Nature , vol.414 , Issue.6865 , pp. 782-787
    • Zimmet, P.1    Alberti, K.G.M.M.2    Shaw, J.3
  • 7
    • 0034031561 scopus 로고    scopus 로고
    • Globalization, coca-colonization and the chronic disease epidemic: Can the Doomsday scenario be averted?
    • Zimmet, P. (2000) Globalization, coca-colonization and the chronic disease epidemic: can the Doomsday scenario be averted? J. Intern. Med. 247, 301-310
    • (2000) J. Intern. Med. , vol.247 , pp. 301-310
    • Zimmet, P.1
  • 8
    • 0032469474 scopus 로고    scopus 로고
    • Mechanisms of insulin resistance in non-oxidative glucose metabolism: The role of glycogen synthase
    • Beck-Nielsen, H. (1998) Mechanisms of insulin resistance in non-oxidative glucose metabolism: the role of glycogen synthase. J. Basic Clin. Physiol. Pharmacol. 9, 255-279
    • (1998) J. Basic Clin. Physiol. Pharmacol. , vol.9 , pp. 255-279
    • Beck-Nielsen, H.1
  • 9
    • 0028091753 scopus 로고
    • Metabolic and genetic characterization of prediabetic states. Sequence of events leading to noninsulin-dependent diabetes mellitus
    • Beck-Nielsen, H., and Groop, L. C. (1994) Metabolic and genetic characterization of prediabetic states. Sequence of events leading to noninsulin-dependent diabetes mellitus. J. Clin. Invest. 94, 1714-1721
    • (1994) J. Clin. Invest. , vol.94 , pp. 1714-1721
    • Beck-Nielsen, H.1    Groop, L.C.2
  • 10
    • 0141678155 scopus 로고    scopus 로고
    • Metabolic and genetic influence on glucose metabolism in type 2 diabetic subjects-experiences from relatives and twin studies
    • Beck-Nielsen, H., Vaag, A., Poulsen, P., and Gaster, M. (2003) Metabolic and genetic influence on glucose metabolism in type 2 diabetic subjects-experiences from relatives and twin studies. Best Pract. Res. Clin. Endocrinol. Metab. 17, 445-467
    • (2003) Best Pract. Res. Clin. Endocrinol. Metab. , vol.17 , pp. 445-467
    • Beck-Nielsen, H.1    Vaag, A.2    Poulsen, P.3    Gaster, M.4
  • 14
    • 0030895921 scopus 로고    scopus 로고
    • A comparison of selected mRNA and protein abundances in human liver
    • DOI 10.1002/elps.1150180333
    • Anderson, L., and Seilhamer, J. (1997) A comparison of selected mRNA and protein abundances in human liver. Electrophoresis 18, 533-537 (Pubitemid 27174443)
    • (1997) Electrophoresis , vol.18 , Issue.3-4 , pp. 533-537
    • Anderson, L.1    Seilhamer, J.2
  • 16
    • 0029134591 scopus 로고
    • Insulin action and glucose metabolism in nondiabetic control and NIDDM subjects. Comparison using human skeletal muscle cell cultures
    • Henry, R. R., Abrams, L., Nikoulina, S., and Ciaraldi, T. P. (1995) Insulin action and glucose metabolism in nondiabetic control and NIDDM subjects. Comparison using human skeletal muscle cell cultures. Diabetes 44, 936-946
    • (1995) Diabetes , vol.44 , pp. 936-946
    • Henry, R.R.1    Abrams, L.2    Nikoulina, S.3    Ciaraldi, T.P.4
  • 17
    • 0030010373 scopus 로고    scopus 로고
    • Acquired defects of glycogen synthase activity in cultured human skeletal muscle cells: Influence of high glucose and insulin levels
    • Henry, R. R., Ciaraldi, T. P., Mudaliar, S., Abrams, L., and Nikoulina, S. E. (1996) Acquired defects of glycogen synthase activity in cultured human skeletal muscle cells: influence of high glucose and insulin levels. Diabetes 45, 400-407 (Pubitemid 26110243)
    • (1996) Diabetes , vol.45 , Issue.4 , pp. 400-407
    • Henry, R.R.1    Ciaraldi, T.P.2    Mudaliar, S.3    Abrams, L.4    Nikoulina, S.E.5
  • 18
    • 4344701517 scopus 로고    scopus 로고
    • The reduced insulin-mediated glucose oxidation in skeletal muscle from type 2 diabetic subjects may be of genetic origin-evidence from cultured myotubes
    • Gaster, M., and Beck-Nielsen, H. (2004) The reduced insulin-mediated glucose oxidation in skeletal muscle from type 2 diabetic subjects may be of genetic origin-evidence from cultured myotubes. Biochim. Biophys. Acta 1690, 85-91
    • (2004) Biochim. Biophys. Acta , vol.1690 , pp. 85-91
    • Gaster, M.1    Beck-Nielsen, H.2
  • 19
    • 2942583031 scopus 로고    scopus 로고
    • The primary defect in glycogen synthase activity is not based on increased glycogen synthase kinase-3alpha activity in diabetic myotubes
    • DOI 10.1016/j.bbrc.2004.05.109, PII S0006291X04011027
    • Gaster, M., Brüsgaard, K., Handberg, A., Højlund, K., Wojtaszewski, J. F., and Beck-Nielsen, H. (2004) The primary defect in glycogen synthase activity is not based on increased glycogen synthase kinase-3alpha activity in diabetic myotubes. Biochem. Biophys. Res. Commun. 319, 1235-1240 (Pubitemid 38759543)
    • (2004) Biochemical and Biophysical Research Communications , vol.319 , Issue.4 , pp. 1235-1240
    • Gaster, M.1    Brusgaard, K.2    Handberg, A.3    Hojlund, K.4    Wojtaszewski, J.F.P.5    Beck-Nielsen, H.6
  • 20
    • 1442326017 scopus 로고    scopus 로고
    • Reduced lipid oxidation in skeletal muscle from type 2 diabetic subjects may be of genetic origin: Evidence from cultured myotubes
    • Gaster, M., Rustan, A. C., Aas, V., and Beck-Nielsen, H. (2004) Reduced lipid oxidation in skeletal muscle from type 2 diabetic subjects may be of genetic origin: evidence from cultured myotubes. Diabetes 53, 542-548
    • (2004) Diabetes , vol.53 , pp. 542-548
    • Gaster, M.1    Rustan, A.C.2    Aas, V.3    Beck-Nielsen, H.4
  • 21
    • 0036224284 scopus 로고    scopus 로고
    • The diabetic phenotype is conserved in myotubes established from diabetic subjects: Evidence for primary defects in glucose transport and glycogen synthase activity
    • Gaster, M., Petersen, I., Højlund, K., Poulsen, P., and Beck-Nielsen, H. (2002) The diabetic phenotype is conserved in myotubes established from diabetic subjects: evidence for primary defects in glucose transport and glycogen synthase activity. Diabetes 51, 921-927 (Pubitemid 34438332)
    • (2002) Diabetes , vol.51 , Issue.4 , pp. 921-927
    • Gaster, M.1    Petersen, I.2    Hojlund, K.3    Poulsen, P.4    Beck-Nielsen, H.5
  • 22
    • 0035672377 scopus 로고    scopus 로고
    • A cellular model system of differentiated human myotubes
    • Gaster, M., Kristensen, S. R., Beck-Nielsen, H., and Schrøder, H. D. (2001) A cellular model system of differentiated human myotubes. APMIS 109, 735-744 (Pubitemid 34015455)
    • (2001) APMIS , vol.109 , Issue.11 , pp. 735-744
    • Gaster, M.1    Kristensen, S.R.2    Beck-Nielsen, H.3    Schroder, H.D.4
  • 23
    • 34250021550 scopus 로고    scopus 로고
    • Reduced TCA -flux in diabetic myotubes: A governing influence on the diabetic phenotype?
    • Gaster, M. (2007) Reduced TCA -flux in diabetic myotubes: A governing influence on the diabetic phenotype ? Biochem. Biophys. Res. Commun. 1772, 755-765
    • (2007) Biochem. Biophys. Res. Commun. , vol.1772 , pp. 755-765
    • Gaster, M.1
  • 24
    • 64549139279 scopus 로고    scopus 로고
    • Reduced lipid oxidation in human myotubes established from obese and type 2 diabetic subjects
    • Gaster, M. (2009) Reduced lipid oxidation in human myotubes established from obese and type 2 diabetic subjects. Biochem. Biophys. Res. Commun. 382, 766-770
    • (2009) Biochem. Biophys. Res. Commun. , vol.382 , pp. 766-770
    • Gaster, M.1
  • 25
    • 78049264842 scopus 로고    scopus 로고
    • ATP synthesis is impaired in isolated mitochondria from myotubes established from type 2 diabetic subjects
    • Minet, A. D., and Gaster, M. (2010) ATP synthesis is impaired in isolated mitochondria from myotubes established from type 2 diabetic subjects. Biochem. Biophys. Res. Commun. 402, 70-74
    • (2010) Biochem. Biophys. Res. Commun. , vol.402 , pp. 70-74
    • Minet, A.D.1    Gaster, M.2
  • 27
    • 0036583926 scopus 로고    scopus 로고
    • Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics
    • Ong, S. E., Blagoev, B., Kratchmarova, I., Kristensen, D. B., Steen, H., Pandey, A., and Mann, M. (2002) Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol. Cell Proteomics 1, 376-386
    • (2002) Mol. Cell Proteomics , vol.1 , pp. 376-386
    • Ong, S.E.1    Blagoev, B.2    Kratchmarova, I.3    Kristensen, D.B.4    Steen, H.5    Pandey, A.6    Mann, M.7
  • 28
    • 0036428393 scopus 로고    scopus 로고
    • Amino acid residue specific stable isotope labeling for quantitative proteomics
    • DOI 10.1002/rcm.831
    • Zhu, H., Pan, S., Gu, S., Bradbury, E. M., and Chen, X. (2002) Amino acid residue specific stable isotope labeling for quantitative proteomics. Rapid Commun. Mass Spectrom. 16, 2115-2123 (Pubitemid 35340078)
    • (2002) Rapid Communications in Mass Spectrometry , vol.16 , Issue.22 , pp. 2115-2123
    • Zhu, H.1    Pan, S.2    Gu, S.3    Morton, B.E.4    Chen, X.5
  • 30
    • 54049090766 scopus 로고    scopus 로고
    • Selected reaction monitoring for quantitative proteomics: A tutorial
    • Lange, V., Picotti, P., Domon, B., and Aebersold, R. (2008) Selected reaction monitoring for quantitative proteomics: a tutorial. Mol. Syst. Biol. 4, 222
    • (2008) Mol. Syst. Biol. , vol.4 , pp. 222
    • Lange, V.1    Picotti, P.2    Domon, B.3    Aebersold, R.4
  • 31
    • 68749094119 scopus 로고    scopus 로고
    • Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics
    • Picotti, P., Bodenmiller, B., Mueller, L. N., Domon, B., and Aebersold, R. (2009) Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics. Cell 138, 795-806
    • (2009) Cell , vol.138 , pp. 795-806
    • Picotti, P.1    Bodenmiller, B.2    Mueller, L.N.3    Domon, B.4    Aebersold, R.5
  • 32
    • 20444463198 scopus 로고    scopus 로고
    • Reduced insulin-mediated citrate synthase activity in cultured skeletal muscle cells from patients with type 2 diabetes: Evidence for an intrinsic oxidative enzyme defect
    • DOI 10.1016/j.bbadis.2005.04.001, PII S0925443905000360
    • Ortenblad, N., Mogensen, M., Petersen, I., Højlund, K., Levin, K., Sahlin, K., Beck-Nielsen, H., and Gaster, M. (2005) Reduced insulin-mediated citrate synthase activity in cultured skeletal muscle cells from patients with type 2 diabetes: evidence for an intrinsic oxidative enzyme defect. Biochim. Biophys. Acta 1741, 206-214 (Pubitemid 40825006)
    • (2005) Biochimica et Biophysica Acta - Molecular Basis of Disease , vol.1741 , Issue.1-2 , pp. 206-214
    • Ortenblad, N.1    Mogensen, M.2    Petersen, I.3    Hojlund, K.4    Levin, K.5    Sahlin, K.6    Beck-Nielsen, H.7    Gaster, M.8
  • 33
    • 33646065654 scopus 로고    scopus 로고
    • Triacylglycerol accumulation is not primarily affected in myotubes established from type 2 diabetic subjects
    • Gaster, M., and Beck-Nielsen, H. (2006) Triacylglycerol accumulation is not primarily affected in myotubes established from type 2 diabetic subjects. Biochim. Biophys. Acta 1761, 100-110
    • (2006) Biochim. Biophys. Acta , vol.1761 , pp. 100-110
    • Gaster, M.1    Beck-Nielsen, H.2
  • 34
    • 0016723939 scopus 로고
    • Percutaneous needle biopsy of skeletal muscle in physiological and clinical research
    • Bergstrom, J. (1975) Percutaneous needle biopsy of skeletal muscle in physiological and clinical research. Scand. J. Clin. Lab. Invest. 35, 609-616
    • (1975) Scand. J. Clin. Lab. Invest. , vol.35 , pp. 609-616
    • Bergstrom, J.1
  • 35
    • 0035675446 scopus 로고    scopus 로고
    • Proliferation conditions for human satellite cells. The fractional content of satellite cells
    • Gaster, M., Beck-Nielsen, H., and Schrøder, H. D. (2001) Proliferation conditions for human satellite cells. The fractional content of satellite cells. APMIS 109, 726-734 (Pubitemid 34015454)
    • (2001) APMIS , vol.109 , Issue.11 , pp. 726-734
    • Gaster, M.1    Beck-Nielsen, H.2    Schroder, H.D.3
  • 36
    • 0035969561 scopus 로고    scopus 로고
    • The basal kinetic parameters of glycogen synthase in human myotube cultures are not affected by chronic high insulin exposure
    • DOI 10.1016/S0925-4439(01)00071-0, PII S0925443901000710
    • Gaster, M., Schrøder, H. D., Handberg, A., and Beck-Nielsen, H. (2001) The basal kinetic parameters of glycogen synthase in human myotube cultures are not affected by chronic high insulin exposure. Biochim. Biophys. Acta 1537, 211-221 (Pubitemid 33139803)
    • (2001) Biochimica et Biophysica Acta - Molecular Basis of Disease , vol.1537 , Issue.3 , pp. 211-221
    • Gaster, M.1    Schroder, H.D.2    Handberg, A.3    Beck-Nielsen, H.4
  • 37
    • 57649173582 scopus 로고    scopus 로고
    • The dynamic of lipid oxidation in human myotubes
    • Gaster, M. (2009) The dynamic of lipid oxidation in human myotubes. Biochim. Biophys. Acta 1791, 17-24
    • (2009) Biochim. Biophys. Acta , vol.1791 , pp. 17-24
    • Gaster, M.1
  • 38
    • 0033057707 scopus 로고    scopus 로고
    • Sample purification and preparation technique based on nanoscale reversed-phase columns for the sensitive analysis of complex peptide mixtures by matrix-assisted laser desorption/ionization mass spectrometry
    • Gobom, J., Nordhoff, E., Mirgorodskaya, E., Ekman, R., and Roepstorff, P. (1999) Sample purification and preparation technique based on nanoscale reversed-phase columns for the sensitive analysis of complex peptide mixtures by matrix-assisted laser desorption/ionization mass spectrometry. J. Mass Spectrom. 34, 105-116
    • (1999) J. Mass Spectrom. , vol.34 , pp. 105-116
    • Gobom, J.1    Nordhoff, E.2    Mirgorodskaya, E.3    Ekman, R.4    Roepstorff, P.5
  • 39
    • 42649139982 scopus 로고    scopus 로고
    • SIMAC (Sequential Elution from IMAC), a phosphoproteomics strategy for the rapid separation of monophosphorylated from multiply phosphorylated peptides
    • DOI 10.1074/mcp.M700362-MCP200
    • Thingholm, T. E., Jensen, O. N., Robinson, P. J., and Larsen, M. R. (2008) SIMAC - A phosphoproteomic strategy for the rapid separation of monophosphorylated from multiply phosphorylated peptides. Mol Cell Proteomics 7, 661-671 (Pubitemid 351597478)
    • (2008) Molecular and Cellular Proteomics , vol.7 , Issue.4 , pp. 661-671
    • Thingholm, T.E.1    Jensen, O.N.2    Robinson, P.J.3    Larsen, M.R.4
  • 42
    • 12444345515 scopus 로고    scopus 로고
    • Tandem mass tags: A novel quantification strategy for comparative analysis of complex protein mixtures by MS/MS
    • DOI 10.1021/ac0262560
    • Thompson, A., Schäfer, J., Kuhn, K., Kienle, S., Schwarz, J., Schmidt, G., Neumann, T., Johnstone, R., Mohammed, A. K., and Hamon, C. (2003) Tandem mass tags: a novel quantification strategy for comparative analysis of complex protein mixtures by MS/MS. Anal. Chem. 75, 1895-1904 (Pubitemid 36438013)
    • (2003) Analytical Chemistry , vol.75 , Issue.8 , pp. 1895-1904
    • Thompson, A.1    Schafer, J.2    Kuhn, K.3    Kienle, S.4    Schwarz, J.5    Schmidt, G.6    Neumann, T.7    Hamon, C.8
  • 43
    • 77953595441 scopus 로고    scopus 로고
    • Undesirable Charge-Enhancement of Isobaric Tagged Phosphopeptides Leads to Reduced Identification Efficiency
    • Thingholm, T. E., Palmisano, G., Kjeldsen, F., and Larsen, M. R. (2010) Undesirable Charge-Enhancement of Isobaric Tagged Phosphopeptides Leads to Reduced Identification Efficiency. J. Proteome Res 9, 4045-4052
    • (2010) J. Proteome Res , vol.9 , pp. 4045-4052
    • Thingholm, T.E.1    Palmisano, G.2    Kjeldsen, F.3    Larsen, M.R.4
  • 44
    • 37249053773 scopus 로고    scopus 로고
    • Peptide sequencing and characterization of post-translational modifications by enhanced ion-charging and liquid chromatography electron-transfer dissociation tandem mass spectrometry
    • DOI 10.1021/ac701700g
    • Kjeldsen, F., Giessing, A. M., Ingrell, C. R., and Jensen, O. N. (2007) Peptide sequencing and characterization of post-translational modifications by enhanced ion-charging and liquid chromatography electron-transfer dissociation tandem mass spectrometry. Anal. Chem. 79, 9243-9252 (Pubitemid 350276301)
    • (2007) Analytical Chemistry , vol.79 , Issue.24 , pp. 9243-9252
    • Kjeldsen, F.1    Giessing, A.M.B.2    Ingrell, C.R.3    Jensen, O.N.4
  • 46
    • 0036266251 scopus 로고    scopus 로고
    • Gene expression profile in skeletal muscle of type 2 diabetes and the effect of insulin treatment
    • Sreekumar, R., Halvatsiotis, P., Schimke, J. C., and Nair, K. S. (2002) Gene expression profile in skeletal muscle of type 2 diabetes and the effect of insulin treatment. Diabetes 51, 1913-1920 (Pubitemid 34564306)
    • (2002) Diabetes , vol.51 , Issue.6 , pp. 1913-1920
    • Sreekumar, R.1    Halvatsiotis, P.2    Schimke, J.C.3    Sreekumaran, N.K.4
  • 47
  • 48
    • 0034987199 scopus 로고    scopus 로고
    • GLUT4 is reduced in slow muscle fibers of type 2 diabetic patients: Is insulin resistance in type 2 diabetes a slow, type 1 fiber disease?
    • Gaster, M., Staehr, P., Beck-Nielsen, H., Schrøder, H. D., and Handberg, A. (2001) GLUT4 is reduced in slow muscle fibers of type 2 diabetic patients: is insulin resistance in type 2 diabetes a slow, type 1 fiber disease? Diabetes 50, 1324-1329 (Pubitemid 32500164)
    • (2001) Diabetes , vol.50 , Issue.6 , pp. 1324-1329
    • Gaster, M.1    Staehr, P.2    Beck-Nielsen, H.3    Schroder, H.D.4    Handberg, A.5
  • 49
    • 0030669471 scopus 로고    scopus 로고
    • Evidence of an increased number of type IIb muscle fibers in insulin- resistant first-degree relatives of patients with NIDDM
    • Nyholm, B., Qu, Z., Kaal, A., Pedersen, S. B., Gravholt, C. H., Andersen, J. L., Saltin, B., and Schmitz, O. (1997) Evidence of an increased number of type IIb muscle fibers in insulin-resistant first-degree relatives of patients with NIDDM. Diabetes 46, 1822-1828 (Pubitemid 27456417)
    • (1997) Diabetes , vol.46 , Issue.11 , pp. 1822-1828
    • Nyholm, B.1    Qu, Z.2    Kaal, A.3    Pedersen, S.B.4    Gravholt, C.H.5    Andersen, J.L.6    Saltin, B.7    Schmitz, O.8
  • 51
    • 0024425880 scopus 로고
    • Maturity-onset diabetes of the young (MODY)
    • Fajans, S. S. (1989) Maturity-onset diabetes of the young (MODY). Diabetes Metab. Rev. 5, 579-606
    • (1989) Diabetes Metab. Rev. , vol.5 , pp. 579-606
    • Fajans, S.S.1
  • 52
    • 0025057199 scopus 로고
    • Scope and heterogeneous nature of MODY
    • Fajans, S. S. (1990) Scope and heterogeneous nature of MODY. Diabetes Care 13, 49-64
    • (1990) Diabetes Care , vol.13 , pp. 49-64
    • Fajans, S.S.1
  • 53
    • 0023672777 scopus 로고
    • Effects of adenosine deaminase on the sensitivity of glucose transport, glycolysis and glycogen synthesis to insulin in muscles of the rat
    • Leighton, B., Lozeman, F. J., Vlachonikolis, I. G., Challiss, R. A., Pitcher, J. A., and Newsholme, E. A. (1988) Effects of adenosine deaminase on the sensitivity of glucose transport, glycolysis and glycogen synthesis to insulin in muscles of the rat. Int. J. Biochem. 20, 23-27
    • (1988) Int. J. Biochem. , vol.20 , pp. 23-27
    • Leighton, B.1    Lozeman, F.J.2    Vlachonikolis, I.G.3    Challiss, R.A.4    Pitcher, J.A.5    Newsholme, E.A.6
  • 54
    • 33845468278 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV (DPP IV) inhibitors: A newly emerging drug class for the treatment of type 2 diabetes
    • DOI 10.3132/dvdr.2006.024
    • Green, B. D., Flatt, P. R., and Bailey, C. J. (2006) Dipeptidyl peptidase IV (DPP IV) inhibitors: A newly emerging drug class for the treatment of type 2 diabetes. Diab. Vasc. Dis. Res. 3, 159-165 (Pubitemid 44902481)
    • (2006) Diabetes and Vascular Disease Research , vol.3 , Issue.3 , pp. 159-165
    • Green, B.D.1    Flatt, P.R.2    Bailey, C.J.3
  • 55
    • 0035723325 scopus 로고    scopus 로고
    • CD26: A multifunctional integral membrane and secreted protein of activated lymphocytes
    • DOI 10.1046/j.1365-3083.2001.00984.x
    • Gorrell, M. D., Gysbers, V., and McCaughan, G. W. (2001) CD26: a multifunctional integral membrane and secreted protein of activated lymphocytes. Scand J. Immunol. 54, 249-264 (Pubitemid 34205737)
    • (2001) Scandinavian Journal of Immunology , vol.54 , Issue.3 , pp. 249-264
    • Gorrell, M.D.1    Gysbers, V.2    McCaughan, G.W.3
  • 56
    • 0037234531 scopus 로고    scopus 로고
    • Therapeutic potential of dipeptidyl peptidase IV inhibitors for the treatment of type 2 diabetes
    • Drucker, D. J. (2003) Therapeutic potential of dipeptidyl peptidase IV inhibitors for the treatment of type 2 diabetes. Expert Opin. Investig. Drugs 12, 87-100
    • (2003) Expert Opin. Investig. Drugs , vol.12 , pp. 87-100
    • Drucker, D.J.1
  • 59
    • 15944404686 scopus 로고    scopus 로고
    • The therapeutic potential of inhibitors of dipeptidyl peptidase IV (DPP IV) and related proline-specific dipeptidyl aminopeptidases
    • DOI 10.2174/0929867053507298
    • Augustyns, K., Van der Veken, P., Senten, K., and Haemers, A. (2005) The therapeutic potential of inhibitors of dipeptidyl peptidase IV (DPP IV) and related proline-specific dipeptidyl aminopeptidases. Curr. Med. Chem. 12, 971-998 (Pubitemid 40443851)
    • (2005) Current Medicinal Chemistry , vol.12 , Issue.8 , pp. 971-998
    • Augustyns, K.1    Van Der, V.P.2    Senten, K.3    Haemers, A.4
  • 63
    • 33748531290 scopus 로고    scopus 로고
    • Inhibition of dipeptidyl peptidase-IV activity by metformin enhances the antidiabetic effects of glucagon-like peptide-1
    • DOI 10.1016/j.ejphar.2006.07.043, PII S001429990600776X
    • Green, B. D., Irwin, N., Duffy, N. A., Gault, V. A., O'harte, F, P., and Flatt, P. R. (2006) Inhibition of dipeptidyl peptidase-IV activity by metformin enhances the antidiabetic effects of glucagon-like peptide-1. Eur. J. Pharmacol. 547, 192-199 (Pubitemid 44373906)
    • (2006) European Journal of Pharmacology , vol.547 , Issue.1-3 , pp. 192-199
    • Green, B.D.1    Irwin, N.2    Duffy, N.A.3    Gault, V.A.4    O'Harte, F.P.M.5    Flatt, P.R.6
  • 64
    • 65249190795 scopus 로고    scopus 로고
    • Proteomics-based identification of differentially-expressed proteins including galectin-1 in the blood plasma of type 2 diabetic patients
    • Liu, X., Feng, Q., Chen, Y., Zuo, J., Gupta, N., Chang, Y., and Fang, F. (2009) Proteomics-based identification of differentially-expressed proteins including galectin-1 in the blood plasma of type 2 diabetic patients. J. Proteome Res. 8, 1255-1262
    • (2009) J. Proteome Res. , vol.8 , pp. 1255-1262
    • Liu, X.1    Feng, Q.2    Chen, Y.3    Zuo, J.4    Gupta, N.5    Chang, Y.6    Fang, F.7
  • 65
    • 1442326015 scopus 로고    scopus 로고
    • Transcriptional Control of Apolipoprotein A-I Gene Expression in Diabetes
    • DOI 10.2337/diabetes.53.3.513
    • Mooradian, A. D., Haas, M. J., and Wong, N. C. (2004) Transcriptional control of apolipoprotein A-I gene expression in diabetes. Diabetes 53, 513-520 (Pubitemid 38270617)
    • (2004) Diabetes , vol.53 , Issue.3 , pp. 513-520
    • Mooradian, A.D.1    Haas, M.J.2    Wong, N.C.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.