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Volumn 6, Issue 9, 2011, Pages

Different toll-like receptor stimuli have a profound impact on cytokines required to break tolerance and induce autoimmunity

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 12; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; ALPHA INTERFERON; CYTOKINE; GLYCOPROTEIN; LIPOPOLYSACCHARIDE;

EID: 80052611973     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023940     Document Type: Article
Times cited : (16)

References (70)
  • 1
    • 36049033394 scopus 로고    scopus 로고
    • Signaling to NF-kappaB by Toll-like receptors
    • Kawai T, Akira S, (2007) Signaling to NF-kappaB by Toll-like receptors. Trends Mol Med 13: 460-469.
    • (2007) Trends Mol Med , vol.13 , pp. 460-469
    • Kawai, T.1    Akira, S.2
  • 2
    • 74549167783 scopus 로고    scopus 로고
    • Regulation of adaptive immunity by the innate immune system
    • Iwasaki A, Medzhitov R, (2010) Regulation of adaptive immunity by the innate immune system. Science 327: 291-295.
    • (2010) Science , vol.327 , pp. 291-295
    • Iwasaki, A.1    Medzhitov, R.2
  • 3
    • 33748447541 scopus 로고    scopus 로고
    • Type I interferon in systemic lupus erythematosus and other autoimmune diseases
    • Banchereau J, Pascual V, (2006) Type I interferon in systemic lupus erythematosus and other autoimmune diseases. Immunity 25: 383-392.
    • (2006) Immunity , vol.25 , pp. 383-392
    • Banchereau, J.1    Pascual, V.2
  • 5
    • 0034608389 scopus 로고    scopus 로고
    • Role of antigen-presenting cells in mediating tolerance and autoimmunity
    • Garza KM, Chan SM, Suri R, Nguyen LT, Odermatt B, et al. (2000) Role of antigen-presenting cells in mediating tolerance and autoimmunity. J Exp Med 191: 2021-2027.
    • (2000) J Exp Med , vol.191 , pp. 2021-2027
    • Garza, K.M.1    Chan, S.M.2    Suri, R.3    Nguyen, L.T.4    Odermatt, B.5
  • 6
    • 20044385554 scopus 로고    scopus 로고
    • Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease
    • Lang KS, Recher M, Junt T, Navarini AA, Harris NL, et al. (2005) Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease. Nat Med 11: 138-145.
    • (2005) Nat Med , vol.11 , pp. 138-145
    • Lang, K.S.1    Recher, M.2    Junt, T.3    Navarini, A.A.4    Harris, N.L.5
  • 7
    • 2142821465 scopus 로고    scopus 로고
    • Activation of antigen-presenting cells by microbial products breaks self tolerance and induces autoimmune disease
    • Waldner H, Collins M, Kuchroo VK, (2004) Activation of antigen-presenting cells by microbial products breaks self tolerance and induces autoimmune disease. J Clin Invest 113: 990-997.
    • (2004) J Clin Invest , vol.113 , pp. 990-997
    • Waldner, H.1    Collins, M.2    Kuchroo, V.K.3
  • 8
    • 10744228908 scopus 로고    scopus 로고
    • Dendritic cell-induced autoimmune heart failure requires cooperation between adaptive and innate immunity
    • Eriksson U, Ricci R, Hunziker L, Kurrer MO, Oudit GY, et al. (2003) Dendritic cell-induced autoimmune heart failure requires cooperation between adaptive and innate immunity. Nat Med 9: 1484-1490.
    • (2003) Nat Med , vol.9 , pp. 1484-1490
    • Eriksson, U.1    Ricci, R.2    Hunziker, L.3    Kurrer, M.O.4    Oudit, G.Y.5
  • 9
    • 50549089324 scopus 로고    scopus 로고
    • Inhibition of experimental autoimmune myocarditis: peripheral deletion of TcR Vbeta 8.1, 8.2+ CD4+ T cells in TLR-4 deficient mice
    • Gonnella PA, Waldner H, Del Nido PJ, McGowan FX, (2008) Inhibition of experimental autoimmune myocarditis: peripheral deletion of TcR Vbeta 8.1, 8.2+ CD4+ T cells in TLR-4 deficient mice. J Autoimmun 31: 180-187.
    • (2008) J Autoimmun , vol.31 , pp. 180-187
    • Gonnella, P.A.1    Waldner, H.2    del Nido, P.J.3    McGowan, F.X.4
  • 11
    • 0035115080 scopus 로고    scopus 로고
    • Signaling by toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages
    • Hirschfeld M, Weis JJ, Toshchakov V, Salkowski CA, Cody MJ, et al. (2001) Signaling by toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages. Infect Immun 69: 1477-1482.
    • (2001) Infect Immun , vol.69 , pp. 1477-1482
    • Hirschfeld, M.1    Weis, J.J.2    Toshchakov, V.3    Salkowski, C.A.4    Cody, M.J.5
  • 12
    • 0035813157 scopus 로고    scopus 로고
    • Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells
    • Re F, Strominger JL, (2001) Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells. J Biol Chem 276: 37692-37699.
    • (2001) J Biol Chem , vol.276 , pp. 37692-37699
    • Re, F.1    Strominger, J.L.2
  • 13
    • 0033213590 scopus 로고    scopus 로고
    • Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
    • Takeuchi O, Hoshino K, Kawai T, Sanjo H, Takada H, et al. (1999) Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11: 443-451.
    • (1999) Immunity , vol.11 , pp. 443-451
    • Takeuchi, O.1    Hoshino, K.2    Kawai, T.3    Sanjo, H.4    Takada, H.5
  • 14
    • 0042679529 scopus 로고    scopus 로고
    • Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
    • Hoebe K, Du X, Georgel P, Janssen E, Tabeta K, et al. (2003) Identification of Lps2 as a key transducer of MyD88-independent TIR signalling. Nature 424: 743-748.
    • (2003) Nature , vol.424 , pp. 743-748
    • Hoebe, K.1    Du, X.2    Georgel, P.3    Janssen, E.4    Tabeta, K.5
  • 15
    • 0043176281 scopus 로고    scopus 로고
    • Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
    • Yamamoto M, Sato S, Hemmi H, Hoshino K, Kaisho T, et al. (2003) Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 301: 640-643.
    • (2003) Science , vol.301 , pp. 640-643
    • Yamamoto, M.1    Sato, S.2    Hemmi, H.3    Hoshino, K.4    Kaisho, T.5
  • 16
    • 17144404177 scopus 로고    scopus 로고
    • IRF-7 is the master regulator of type-I interferon-dependent immune responses
    • Honda K, Yanai H, Negishi H, Asagiri M, Sato M, et al. (2005) IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 434: 772-777.
    • (2005) Nature , vol.434 , pp. 772-777
    • Honda, K.1    Yanai, H.2    Negishi, H.3    Asagiri, M.4    Sato, M.5
  • 17
    • 33746884630 scopus 로고    scopus 로고
    • Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation
    • Guiducci C, Ott G, Chan JH, Damon E, Calacsan C, et al. (2006) Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation. J Exp Med 203: 1999-2008.
    • (2006) J Exp Med , vol.203 , pp. 1999-2008
    • Guiducci, C.1    Ott, G.2    Chan, J.H.3    Damon, E.4    Calacsan, C.5
  • 18
    • 17844380477 scopus 로고    scopus 로고
    • Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction
    • Honda K, Ohba Y, Yanai H, Negishi H, Mizutani T, et al. (2005) Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction. Nature 434: 1035-1040.
    • (2005) Nature , vol.434 , pp. 1035-1040
    • Honda, K.1    Ohba, Y.2    Yanai, H.3    Negishi, H.4    Mizutani, T.5
  • 19
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • Trinchieri G, (2003) Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol 3: 133-146.
    • (2003) Nat Rev Immunol , vol.3 , pp. 133-146
    • Trinchieri, G.1
  • 20
    • 0034763143 scopus 로고    scopus 로고
    • Regulation of interleukin-12 production in antigen-presenting cells
    • Ma X, Trinchieri G, (2001) Regulation of interleukin-12 production in antigen-presenting cells. Adv Immunol 79: 55-92.
    • (2001) Adv Immunol , vol.79 , pp. 55-92
    • Ma, X.1    Trinchieri, G.2
  • 21
    • 58049209834 scopus 로고    scopus 로고
    • Inflammatory signals in dendritic cell activation and the induction of adaptive immunity
    • Joffre O, Nolte MA, Sporri R, Reis e Sousa C, (2009) Inflammatory signals in dendritic cell activation and the induction of adaptive immunity. Immunol Rev 227: 234-247.
    • (2009) Immunol Rev , vol.227 , pp. 234-247
    • Joffre, O.1    Nolte, M.A.2    Sporri, R.3    Reis e Sousa, C.4
  • 22
    • 34447254518 scopus 로고    scopus 로고
    • CD8- DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS
    • Skokos D, Nussenzweig MC, (2007) CD8- DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS. J Exp Med 204: 1525-1531.
    • (2007) J Exp Med , vol.204 , pp. 1525-1531
    • Skokos, D.1    Nussenzweig, M.C.2
  • 23
    • 33745074981 scopus 로고    scopus 로고
    • Signals required for programming effector and memory development by CD8+ T cells
    • Mescher MF, Curtsinger JM, Agarwal P, Casey KA, Gerner M, et al. (2006) Signals required for programming effector and memory development by CD8+ T cells. Immunol Rev 211: 81-92.
    • (2006) Immunol Rev , vol.211 , pp. 81-92
    • Mescher, M.F.1    Curtsinger, J.M.2    Agarwal, P.3    Casey, K.A.4    Gerner, M.5
  • 24
    • 0042575473 scopus 로고    scopus 로고
    • P-selectin and P-selectin glycoprotein ligand 1 are major determinants for Th1 cell recruitment to nonlymphoid effector sites in the intestinal lamina propria
    • Haddad W, Cooper CJ, Zhang Z, Brown JB, Zhu Y, et al. (2003) P-selectin and P-selectin glycoprotein ligand 1 are major determinants for Th1 cell recruitment to nonlymphoid effector sites in the intestinal lamina propria. J Exp Med 198: 369-377.
    • (2003) J Exp Med , vol.198 , pp. 369-377
    • Haddad, W.1    Cooper, C.J.2    Zhang, Z.3    Brown, J.B.4    Zhu, Y.5
  • 25
    • 67651149582 scopus 로고    scopus 로고
    • Generation of human dendritic cells that simultaneously secrete IL-12 and have migratory capacity by adenoviral gene transfer of hCD40L in combination with IFN-gamma
    • Knippertz I, Hesse A, Schunder T, Kampgen E, Brenner MK, et al. (2009) Generation of human dendritic cells that simultaneously secrete IL-12 and have migratory capacity by adenoviral gene transfer of hCD40L in combination with IFN-gamma. J Immunother 32: 524-538.
    • (2009) J Immunother , vol.32 , pp. 524-538
    • Knippertz, I.1    Hesse, A.2    Schunder, T.3    Kampgen, E.4    Brenner, M.K.5
  • 26
    • 58149157948 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells into immunostimulatory dendritic cells under feeder-free culture conditions
    • Su Z, Frye C, Bae KM, Kelley V, Vieweg J, (2008) Differentiation of human embryonic stem cells into immunostimulatory dendritic cells under feeder-free culture conditions. Clin Cancer Res 14: 6207-6217.
    • (2008) Clin Cancer Res , vol.14 , pp. 6207-6217
    • Su, Z.1    Frye, C.2    Bae, K.M.3    Kelley, V.4    Vieweg, J.5
  • 27
    • 0033939014 scopus 로고    scopus 로고
    • Aberrant macrophage cytokine production is a conserved feature among autoimmune-prone mouse strains: elevated interleukin (IL)-12 and an imbalance in tumor necrosis factor-alpha and IL-10 define a unique cytokine profile in macrophages from young nonobese diabetic mice
    • Alleva DG, Pavlovich RP, Grant C, Kaser SB, Beller DI, (2000) Aberrant macrophage cytokine production is a conserved feature among autoimmune-prone mouse strains: elevated interleukin (IL)-12 and an imbalance in tumor necrosis factor-alpha and IL-10 define a unique cytokine profile in macrophages from young nonobese diabetic mice. Diabetes 49: 1106-1115.
    • (2000) Diabetes , vol.49 , pp. 1106-1115
    • Alleva, D.G.1    Pavlovich, R.P.2    Grant, C.3    Kaser, S.B.4    Beller, D.I.5
  • 28
    • 0037408257 scopus 로고    scopus 로고
    • Distinct pathways for NF-kappa B regulation are associated with aberrant macrophage IL-12 production in lupus- and diabetes-prone mouse strains
    • Liu J, Beller DI, (2003) Distinct pathways for NF-kappa B regulation are associated with aberrant macrophage IL-12 production in lupus- and diabetes-prone mouse strains. J Immunol 170: 4489-4496.
    • (2003) J Immunol , vol.170 , pp. 4489-4496
    • Liu, J.1    Beller, D.I.2
  • 29
    • 0037370261 scopus 로고    scopus 로고
    • IL-12 is required for differentiation of pathogenic CD8+ T cell effectors that cause myocarditis
    • Grabie N, Delfs MW, Westrich JR, Love VA, Stavrakis G, et al. (2003) IL-12 is required for differentiation of pathogenic CD8+ T cell effectors that cause myocarditis. J Clin Invest 111: 671-680.
    • (2003) J Clin Invest , vol.111 , pp. 671-680
    • Grabie, N.1    Delfs, M.W.2    Westrich, J.R.3    Love, V.A.4    Stavrakis, G.5
  • 30
    • 0037514387 scopus 로고    scopus 로고
    • IL-12 administration accelerates autoimmune diabetes in both wild-type and IFN-gamma-deficient nonobese diabetic mice, revealing pathogenic and protective effects of IL-12-induced IFN-gamma
    • Trembleau S, Penna G, Gregori S, Giarratana N, Adorini L, (2003) IL-12 administration accelerates autoimmune diabetes in both wild-type and IFN-gamma-deficient nonobese diabetic mice, revealing pathogenic and protective effects of IL-12-induced IFN-gamma. J Immunol 170: 5491-5501.
    • (2003) J Immunol , vol.170 , pp. 5491-5501
    • Trembleau, S.1    Penna, G.2    Gregori, S.3    Giarratana, N.4    Adorini, L.5
  • 31
    • 1642282126 scopus 로고    scopus 로고
    • Inhibition of STAT4 activation by lisofylline is associated with the protection of autoimmune diabetes
    • Yang Z, Chen M, Fialkow LB, Ellett JD, Wu R, et al. (2003) Inhibition of STAT4 activation by lisofylline is associated with the protection of autoimmune diabetes. Ann N Y Acad Sci 1005: 409-411.
    • (2003) Ann N Y Acad Sci , vol.1005 , pp. 409-411
    • Yang, Z.1    Chen, M.2    Fialkow, L.B.3    Ellett, J.D.4    Wu, R.5
  • 33
    • 0346962972 scopus 로고    scopus 로고
    • Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation
    • Murphy CA, Langrish CL, Chen Y, Blumenschein W, McClanahan T, et al. (2003) Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J Exp Med 198: 1951-1957.
    • (2003) J Exp Med , vol.198 , pp. 1951-1957
    • Murphy, C.A.1    Langrish, C.L.2    Chen, Y.3    Blumenschein, W.4    McClanahan, T.5
  • 34
    • 0037434789 scopus 로고    scopus 로고
    • Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
    • Cua DJ, Sherlock J, Chen Y, Murphy CA, Joyce B, et al. (2003) Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 421: 744-748.
    • (2003) Nature , vol.421 , pp. 744-748
    • Cua, D.J.1    Sherlock, J.2    Chen, Y.3    Murphy, C.A.4    Joyce, B.5
  • 35
    • 36549030784 scopus 로고    scopus 로고
    • The inhibitory cytokine IL-35 contributes to regulatory T-cell function
    • Collison LW, Workman CJ, Kuo TT, Boyd K, Wang Y, et al. (2007) The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature 450: 566-569.
    • (2007) Nature , vol.450 , pp. 566-569
    • Collison, L.W.1    Workman, C.J.2    Kuo, T.T.3    Boyd, K.4    Wang, Y.5
  • 36
    • 0025755292 scopus 로고
    • Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice
    • Ohashi PS, Oehen S, Buerki K, Pircher H, Ohashi CT, et al. (1991) Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice. Cell 65: 305-317.
    • (1991) Cell , vol.65 , pp. 305-317
    • Ohashi, P.S.1    Oehen, S.2    Buerki, K.3    Pircher, H.4    Ohashi, C.T.5
  • 37
    • 0033638507 scopus 로고    scopus 로고
    • Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
    • Oppmann B, Lesley R, Blom B, Timans JC, Xu Y, et al. (2000) Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 13: 715-725.
    • (2000) Immunity , vol.13 , pp. 715-725
    • Oppmann, B.1    Lesley, R.2    Blom, B.3    Timans, J.C.4    Xu, Y.5
  • 38
    • 34249293041 scopus 로고    scopus 로고
    • Molecular basis for checkpoints in the CD8 T cell response: tolerance versus activation
    • Mescher MF, Agarwal P, Casey KA, Hammerbeck CD, Xiao Z, et al. (2007) Molecular basis for checkpoints in the CD8 T cell response: tolerance versus activation. Semin Immunol 19: 153-161.
    • (2007) Semin Immunol , vol.19 , pp. 153-161
    • Mescher, M.F.1    Agarwal, P.2    Casey, K.A.3    Hammerbeck, C.D.4    Xiao, Z.5
  • 39
    • 0024307348 scopus 로고
    • Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
    • Pircher H, Burki K, Lang R, Hengartner H, Zinkernagel RM, (1989) Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature 342: 559-561.
    • (1989) Nature , vol.342 , pp. 559-561
    • Pircher, H.1    Burki, K.2    Lang, R.3    Hengartner, H.4    Zinkernagel, R.M.5
  • 40
    • 33751563152 scopus 로고    scopus 로고
    • Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals
    • Boonstra A, Rajsbaum R, Holman M, Marques R, Asselin-Paturel C, et al. (2006) Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals. J Immunol 177: 7551-7558.
    • (2006) J Immunol , vol.177 , pp. 7551-7558
    • Boonstra, A.1    Rajsbaum, R.2    Holman, M.3    Marques, R.4    Asselin-Paturel, C.5
  • 41
    • 0037460116 scopus 로고    scopus 로고
    • Recognition of pathogen-associated molecular patterns by TLR family
    • Akira S, Hemmi H, (2003) Recognition of pathogen-associated molecular patterns by TLR family. Immunol Lett 85: 85-95.
    • (2003) Immunol Lett , vol.85 , pp. 85-95
    • Akira, S.1    Hemmi, H.2
  • 42
    • 0031017252 scopus 로고    scopus 로고
    • Interferon-alpha/beta inhibition of interleukin 12 and interferon-gamma production in vitro and endogenously during viral infection
    • Cousens LP, Orange JS, Su HC, Biron CA, (1997) Interferon-alpha/beta inhibition of interleukin 12 and interferon-gamma production in vitro and endogenously during viral infection. Proc Natl Acad Sci U S A 94: 634-639.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 634-639
    • Cousens, L.P.1    Orange, J.S.2    Su, H.C.3    Biron, C.A.4
  • 43
    • 33645797125 scopus 로고    scopus 로고
    • CD8 T cells specific for lymphocytic choriomeningitis virus require type I IFN receptor for clonal expansion
    • Aichele P, Unsoeld H, Koschella M, Schweier O, Kalinke U, et al. (2006) CD8 T cells specific for lymphocytic choriomeningitis virus require type I IFN receptor for clonal expansion. J Immunol 176: 4525-4529.
    • (2006) J Immunol , vol.176 , pp. 4525-4529
    • Aichele, P.1    Unsoeld, H.2    Koschella, M.3    Schweier, O.4    Kalinke, U.5
  • 44
    • 24344478196 scopus 로고    scopus 로고
    • Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection
    • Kolumam GA, Thomas S, Thompson LJ, Sprent J, Murali-Krishna K, (2005) Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection. J Exp Med 202: 637-650.
    • (2005) J Exp Med , vol.202 , pp. 637-650
    • Kolumam, G.A.1    Thomas, S.2    Thompson, L.J.3    Sprent, J.4    Murali-Krishna, K.5
  • 45
    • 47249092785 scopus 로고    scopus 로고
    • Development of TLR inhibitors for the treatment of autoimmune diseases
    • Barrat FJ, Coffman RL, (2008) Development of TLR inhibitors for the treatment of autoimmune diseases. Immunol Rev 223: 271-283.
    • (2008) Immunol Rev , vol.223 , pp. 271-283
    • Barrat, F.J.1    Coffman, R.L.2
  • 46
    • 0034978475 scopus 로고    scopus 로고
    • IL-12 plays a pathologic role at the inflammatory loci in the development of diabetes in NOD mice
    • Nitta Y, Kawamoto S, Tashiro F, Aihara H, Yoshimoto T, et al. (2001) IL-12 plays a pathologic role at the inflammatory loci in the development of diabetes in NOD mice. J Autoimmun 16: 97-104.
    • (2001) J Autoimmun , vol.16 , pp. 97-104
    • Nitta, Y.1    Kawamoto, S.2    Tashiro, F.3    Aihara, H.4    Yoshimoto, T.5
  • 47
    • 0031926095 scopus 로고    scopus 로고
    • Role of interleukin-12 in primary influenza virus infection
    • Monteiro JM, Harvey C, Trinchieri G, (1998) Role of interleukin-12 in primary influenza virus infection. J Virol 72: 4825-4831.
    • (1998) J Virol , vol.72 , pp. 4825-4831
    • Monteiro, J.M.1    Harvey, C.2    Trinchieri, G.3
  • 48
    • 0030060232 scopus 로고    scopus 로고
    • An absolute and restricted requirement for IL-12 in natural killer cell IFN-gamma production and antiviral defense. Studies of natural killer and T cell responses in contrasting viral infections
    • Orange JS, Biron CA, (1996) An absolute and restricted requirement for IL-12 in natural killer cell IFN-gamma production and antiviral defense. Studies of natural killer and T cell responses in contrasting viral infections. J Immunol 156: 1138-1142.
    • (1996) J Immunol , vol.156 , pp. 1138-1142
    • Orange, J.S.1    Biron, C.A.2
  • 50
    • 0033556145 scopus 로고    scopus 로고
    • IL-12 is not required for induction of type 1 cytokine responses in viral infections
    • Oxenius A, Karrer U, Zinkernagel RM, Hengartner H, (1999) IL-12 is not required for induction of type 1 cytokine responses in viral infections. J Immunol 162: 965-973.
    • (1999) J Immunol , vol.162 , pp. 965-973
    • Oxenius, A.1    Karrer, U.2    Zinkernagel, R.M.3    Hengartner, H.4
  • 51
    • 0033583516 scopus 로고    scopus 로고
    • Two roads diverged: interferon alpha/beta- and interleukin 12-mediated pathways in promoting T cell interferon gamma responses during viral infection
    • Cousens LP, Peterson R, Hsu S, Dorner A, Altman JD, et al. (1999) Two roads diverged: interferon alpha/beta- and interleukin 12-mediated pathways in promoting T cell interferon gamma responses during viral infection. J Exp Med 189: 1315-1328.
    • (1999) J Exp Med , vol.189 , pp. 1315-1328
    • Cousens, L.P.1    Peterson, R.2    Hsu, S.3    Dorner, A.4    Altman, J.D.5
  • 52
    • 67650445798 scopus 로고    scopus 로고
    • Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant
    • Longhi MP, Trumpfheller C, Idoyaga J, Caskey M, Matos I, et al. (2009) Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant. J Exp Med 206: 1589-1602.
    • (2009) J Exp Med , vol.206 , pp. 1589-1602
    • Longhi, M.P.1    Trumpfheller, C.2    Idoyaga, J.3    Caskey, M.4    Matos, I.5
  • 53
    • 0035900481 scopus 로고    scopus 로고
    • Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus
    • Blanco P, Palucka AK, Gill M, Pascual V, Banchereau J, (2001) Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus. Science 294: 1540-1543.
    • (2001) Science , vol.294 , pp. 1540-1543
    • Blanco, P.1    Palucka, A.K.2    Gill, M.3    Pascual, V.4    Banchereau, J.5
  • 54
    • 0344497091 scopus 로고    scopus 로고
    • Inhibition of lupus by genetic alteration of the interferon-alpha/beta receptor
    • Kono DH, Baccala R, Theofilopoulos AN, (2003) Inhibition of lupus by genetic alteration of the interferon-alpha/beta receptor. Autoimmunity 36: 503-510.
    • (2003) Autoimmunity , vol.36 , pp. 503-510
    • Kono, D.H.1    Baccala, R.2    Theofilopoulos, A.N.3
  • 55
    • 13944260898 scopus 로고    scopus 로고
    • Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function
    • Sporri R, Reis e Sousa C, (2005) Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function. Nat Immunol 6: 163-170.
    • (2005) Nat Immunol , vol.6 , pp. 163-170
    • Sporri, R.1    Reis e Sousa, C.2
  • 56
    • 24144459516 scopus 로고    scopus 로고
    • Interferon-alpha as a mediator of polyinosinic:polycytidylic acid-induced type 1 diabetes
    • Devendra D, Jasinski J, Melanitou E, Nakayama M, Li M, et al. (2005) Interferon-alpha as a mediator of polyinosinic:polycytidylic acid-induced type 1 diabetes. Diabetes 54: 2549-2556.
    • (2005) Diabetes , vol.54 , pp. 2549-2556
    • Devendra, D.1    Jasinski, J.2    Melanitou, E.3    Nakayama, M.4    Li, M.5
  • 57
    • 33748296239 scopus 로고    scopus 로고
    • Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling
    • Lang KS, Georgiev P, Recher M, Navarini AA, Bergthaler A, et al. (2006) Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling. J Clin Invest 116: 2456-2463.
    • (2006) J Clin Invest , vol.116 , pp. 2456-2463
    • Lang, K.S.1    Georgiev, P.2    Recher, M.3    Navarini, A.A.4    Bergthaler, A.5
  • 58
    • 60849104413 scopus 로고    scopus 로고
    • Hematopoietic cell-derived interferon controls viral replication and virus-induced disease
    • Lang PA, Cervantes-Barragan L, Verschoor A, Navarini AA, Recher M, et al. (2009) Hematopoietic cell-derived interferon controls viral replication and virus-induced disease. Blood 113: 1045-1052.
    • (2009) Blood , vol.113 , pp. 1045-1052
    • Lang, P.A.1    Cervantes-Barragan, L.2    Verschoor, A.3    Navarini, A.A.4    Recher, M.5
  • 59
    • 35348968837 scopus 로고    scopus 로고
    • Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation
    • Jiang A, Bloom O, Ono S, Cui W, Unternaehrer J, et al. (2007) Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation. Immunity 27: 610-624.
    • (2007) Immunity , vol.27 , pp. 610-624
    • Jiang, A.1    Bloom, O.2    Ono, S.3    Cui, W.4    Unternaehrer, J.5
  • 60
    • 0037033427 scopus 로고    scopus 로고
    • Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity
    • Menges M, Rossner S, Voigtlander C, Schindler H, Kukutsch NA, et al. (2002) Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity. J Exp Med 195: 15-21.
    • (2002) J Exp Med , vol.195 , pp. 15-21
    • Menges, M.1    Rossner, S.2    Voigtlander, C.3    Schindler, H.4    Kukutsch, N.A.5
  • 61
    • 0037987977 scopus 로고    scopus 로고
    • Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo
    • Wakkach A, Fournier N, Brun V, Breittmayer JP, Cottrez F, et al. (2003) Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo. Immunity 18: 605-617.
    • (2003) Immunity , vol.18 , pp. 605-617
    • Wakkach, A.1    Fournier, N.2    Brun, V.3    Breittmayer, J.P.4    Cottrez, F.5
  • 62
    • 33745712871 scopus 로고    scopus 로고
    • Dendritic cells in a mature age
    • Reis e Sousa C, (2006) Dendritic cells in a mature age. Nat Rev Immunol 6: 476-483.
    • (2006) Nat Rev Immunol , vol.6 , pp. 476-483
    • Reis e Sousa, C.1
  • 63
    • 42649127715 scopus 로고    scopus 로고
    • Using dendritic cell maturation and IL-12 producing capacity as markers of function: a cautionary tale
    • Kaka AS, Foster AE, Weiss HL, Rooney CM, Leen AM, (2008) Using dendritic cell maturation and IL-12 producing capacity as markers of function: a cautionary tale. J Immunother 31: 359-369.
    • (2008) J Immunother , vol.31 , pp. 359-369
    • Kaka, A.S.1    Foster, A.E.2    Weiss, H.L.3    Rooney, C.M.4    Leen, A.M.5
  • 64
    • 16044363695 scopus 로고    scopus 로고
    • IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses
    • Magram J, Connaughton SE, Warrier RR, Carvajal DM, Wu CY, et al. (1996) IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses. Immunity 4: 471-481.
    • (1996) Immunity , vol.4 , pp. 471-481
    • Magram, J.1    Connaughton, S.E.2    Warrier, R.R.3    Carvajal, D.M.4    Wu, C.Y.5
  • 65
    • 0030002111 scopus 로고    scopus 로고
    • Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response
    • Mattner F, Magram J, Ferrante J, Launois P, Di Padova K, et al. (1996) Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response. Eur J Immunol 26: 1553-1559.
    • (1996) Eur J Immunol , vol.26 , pp. 1553-1559
    • Mattner, F.1    Magram, J.2    Ferrante, J.3    Launois, P.4    Di Padova, K.5
  • 66
    • 1342324752 scopus 로고    scopus 로고
    • Compromised humoral and delayed-type hypersensitivity responses in IL-23-deficient mice
    • Ghilardi N, Kljavin N, Chen Q, Lucas S, Gurney AL, et al. (2004) Compromised humoral and delayed-type hypersensitivity responses in IL-23-deficient mice. J Immunol 172: 2827-2833.
    • (2004) J Immunol , vol.172 , pp. 2827-2833
    • Ghilardi, N.1    Kljavin, N.2    Chen, Q.3    Lucas, S.4    Gurney, A.L.5
  • 67
    • 0028070714 scopus 로고
    • Functional role of type I and type II interferons in antiviral defense
    • Muller U, Steinhoff U, Reis LF, Hemmi S, Pavlovic J, et al. (1994) Functional role of type I and type II interferons in antiviral defense. Science 264: 1918-1921.
    • (1994) Science , vol.264 , pp. 1918-1921
    • Muller, U.1    Steinhoff, U.2    Reis, L.F.3    Hemmi, S.4    Pavlovic, J.5
  • 68
  • 69
    • 0025883707 scopus 로고
    • Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates
    • Battegay M, Cooper S, Althage A, Banziger J, Hengartner H, et al. (1991) Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates. J Virol Methods 33: 191-198.
    • (1991) J Virol Methods , vol.33 , pp. 191-198
    • Battegay, M.1    Cooper, S.2    Althage, A.3    Banziger, J.4    Hengartner, H.5
  • 70
    • 0037128173 scopus 로고    scopus 로고
    • Tumor growth enhances cross-presentation leading to limited T cell activation without tolerance
    • Nguyen LT, Elford AR, Murakami K, Garza KM, Schoenberger SP, et al. (2002) Tumor growth enhances cross-presentation leading to limited T cell activation without tolerance. J Exp Med 195: 423-435.
    • (2002) J Exp Med , vol.195 , pp. 423-435
    • Nguyen, L.T.1    Elford, A.R.2    Murakami, K.3    Garza, K.M.4    Schoenberger, S.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.