P-selectin and P-selectin glycoprotein ligand 1 are major determinants for Th1 cell recruitment to nonlymphoid effector sites in the intestinal lamina propria

Journal of Experimental Medicine

Volumn 198, Issue 3, 2003, Pages 369-377

  Haddad, Wael ^a   Cooper, Cristine J ^a   Zhang, Zheng ^a   Brown, Jeffrey B ^a   Zhu, Yuechun ^a   Issekutz, Andrew ^b   Fuss, Ivan ^c   Lee, Hae Ock ^a   Kansas, Geoffrey S ^a   Barrett, Terrence A ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b DALHOUSIE UNIVERSITY   (Canada)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Interleukin 12; Lamina propria; Leukocyte migration; Memory T cells; Small intestine

Indexed keywords

CELL ADHESION MOLECULE; FREUND ADJUVANT; INTERLEUKIN 12; P SELECTIN GLYCOPROTEIN LIGAND 1; PADGEM PROTEIN;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EFFECTOR CELL; INTESTINE MUCOSA; LAMINA PROPRIA; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PEYER PATCH; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BLOCKING; SMALL INTESTINE; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; UPREGULATION;

ADOPTIVE TRANSFER; ANIMALS; CELL MOVEMENT; CELLS, CULTURED; INTERLEUKIN-12; INTESTINE, SMALL; LIGANDS; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; P-SELECTIN; TH1 CELLS; TH2 CELLS;

EID: 0042575473     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20020691     Document Type: Article

References (33)

1. + T cells requires CD40-CD40 ligand interactions for a sustained increase in mucosal IL-12. J. Immunol. 165:2173-2182.
2. Fuss, I.J., M. Neurath, M. Boirivant, J.S. Klein, C. de la Motte, S.A. Strong, C. Fiocchi, and W. Strober. 1996. Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J. Immunol. 157:1261-1270.
3. Hurst, S.D., C.J. Cooper, S.M. Sitterding, J. Choi, R.L. Jump, A.D. Levine, and T.A. Barrett. 1999. The differentiated state of intestinal lamina propria CD4+ T cells results in altered cytokine production, activation threshold, and costimulatory requirements. J. Immunol. 163:5937-5945.
4. Wagner, N., J. Lohler, E.J. Kunkel, K. Ley, E. Leung, G. Krissansen, K. Rajewsky, and W. Muller. 1996. Critical role for beta7 integrins in formation of the gut-associated lymphoid tissue. Nature. 382:366-370.
5. Lefrancois, L., C.M. Parker, S. Olson, W. Muller, N. Wagner, M.P. Schon, and L. Puddington. 1999. The role of β7 integrins in CD8 T cell trafficking during an antiviral immune response. J. Exp. Med. 189:1631-1638.
6. Huleatt, J.W., and L. Lefrancois. 1996. Beta2 integrins and ICAM-1 are involved in establishment of the intestinal mucosal T cell compartment. Immunity. 5:263-273.
7. Xie, H., Y.C. Lim, F.W. Luscinskas, and A.H. Lichtman. 1999. Acquisition of selectin binding and peripheral homing properties by CD4(+) and CD8(+) T cells. J. Exp. Med. 189:1765-1776.
8. Tietz, W., Y. Allemand, E. Borges, D. von Laer, R. Hallmann, D. Vestweber, and A. Hamann. 1998. CD4+ T cells migrate into inflamed skin only if they express ligands for E- and P-selectin. J. Immunol. 161:963-970.
9. Blander, J.M., I. Visintin, C.A. Janeway, Jr., and R. Medzhitov. 1999. Alpha (1,3)-fucosyltransferase VII and alpha(2,3)-sialyltransferase IV are up-regulated in activated CD4 T cells and maintained after their differentiation into Th1 and migration into inflammatory sites. J. Immunol. 163:3746-3752.
10. Hirata, T., G. Merrill-Skoloff, M. Aab, J. Yang, B.C. Furie, and B. Furie. 2000. P-Selectin glycoprotein ligand 1 (PSGL-1) is a physiological ligand for E-selectin in mediating T helper 1 lymphocyte migration. J. Exp. Med. 192:1669-1676.
11. Austrup, F., D. Vestweber, E. Borges, M. Lohning, R. Brauer, U. Herz, H. Renz, R. Hallmann, A. Scheffold, A. Radbruch, and A. Hamann. 1997. P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues. Nature. 385:81-83.
12. Maly, P., A. Thall, B. Petryniak, C.E. Rogers, P.L. Smith, R.M. Marks, R.J. Kelly, K.M. Gersten, G. Cheng, T.L. Saunders, et al. 1996. The alpha(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis. Cell. 86:643-653.
13. Wagers, A.J., C.M. Waters, L.M. Stoolman, and G.S. Kansas. 1998. Interleukin 12 and interleukin 4 control T cell adhesion to endothelial selectins through opposite effects on α1, 3-fucosyltransferase VII gene expression. J. Exp. Med. 188:2225-2231.
14. Lim, Y.C., L. Henault, A.J. Wagers, G.S. Kansas, F.W. Luscinskas, and A.H. Lichtman. 1999. Expression of functional selectin ligands on Th cells is differentially regulated by IL-12 and IL-4. J. Immunol. 162:3193-3201.
15. Lim, Y.C., H. Xie, C.E. Come, S.I. Alexander, M.J. Grusby, A.H. Lichtman, and F.W. Luscinskas. 2001. IL-12, STAT4-dependent up-regulation of CD4(+) T cell core 2 beta-1,6-n-acetylglucosaminyltransferase, an enzyme essential for biosynthesis of P-selectin ligands. J. Immunol. 167:4476-4484.
16. White, S.J., G.H. Underhill, M.H. Kaplan, and G.S. Kansas. 2001. Cutting edge: differential requirements for Stat4 in expression of glycosyltransferases responsible for selectin ligand formation in Th1 cells. J. Immunol. 167:628-631.
17. + T cells activated in cutaneous or mucosal lymphoid tissues. J. Exp. Med. 195:135-141.
18. Wysocka, M., M. Kubin, L.Q. Vieira, L. Ozmen, G. Garotta, P. Scott, and G. Trinchieri. 1995. Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice. Eur. J. Immunol. 25:672-676.
19. Walter, U.M., L.M. Ayer, B.A. Wolitzky, D.D. Wagner, R.O. Hynes, A.M. Manning, and A.C. Issekutz. 1997. Characterization of a novel adhesion function blocking monoclonal antibody to rat/mouse P-selectin generated in the P-selectin-deficient mouse. Hybridoma. 16:249-257.
20. Kulidjian, A.A., A.C. Issekutz, and T.B. Issekutz. 2002. Differential role of E-selectin and P-selectin in T lymphocyte migration to cutaneous inflammatory reactions induced by cytokines. Int. Immunol. 14:751-760.
21. Hamann, A., D.P. Andrew, D. Jablonski-Westrich, B. Holzmann, and E.C. Butcher. 1994. Role of alpha 4-integrins in lymphocyte homing to mucosal tissues in vivo. J. Immunol. 152:3282-3293.
22. Kunkel, E.J., C.L. Ramos, D.A. Steeber, W. Muller, N. Wagner, T.F. Tedder, and K. Ley. 1998. The roles of L-selectin, beta 7 integrins, and P-selectin in leukocyte rolling and adhesion in high endothelial venules of Peyer's patches. J. Immunol. 161:2449-2456.
23. Eppihimer, M.J., B. Wolitzky, D.C. Anderson, M.A. Labow, and D.N. Granger. 1996. Heterogeneity of expression of E- and P-selectins in vivo. Circ. Res. 79:560-569.
24. Kunkel, E.J., and E.C. Butcher. 2002. Chemokines and the tissue-specific migration of lymphocytes. Immunity. 16:1-4.
25. Panes, J., and D.N. Granger. 1998. Leukocyte-endothelial cell interactions: molecular mechanisms and implications in gastrointestinal disease. Gastroenterology. 114:1066-1090.
26. Farmer, D.G., F. Amersi, X.D. Shen, F. Gao, D. Anselmo, J. Ma, S. Dry, S.V. McDiarmid, G. Shaw, R.W. Busuttil, and J. Kupiec-Weglinski. 2002. Improved survival through the reduction of ischemia-reperfusion injury after rat intestinal transplantation using selective P-selectin blockade with P-selectin glycoprotein ligand-Ig. Transplant Proc. 34:985.
27. Gironella, M., M. Molla, A. Salas, A. Soriano, M. Sans, D. Closa, P. Engel, J.M. Pique, and J. Panes. 2002. The role of P-selectin in experimental colitis as determined by antibody immunoblockade and genetically deficient mice. J. Leukoc. Biol. 72:56-64.
28. Yoshida, N., T. Yamaguchi, S. Nakagawa, Y. Nakamura, Y. Naito, and T. Yoshikawa. 2001. Role of P-selectin and intercellular adhesion molecule-1 in TNB-induced colitis in rats. Digestion. 63(Suppl.):81-86.
29. Molla, M., M. Gironella, A. Salas, R. Miquel, S. Perez-delPulgar, C. Conill, P. Engel, A. Biete, J.M. Pique, and J. Panes. 2001. Role of P-selectin in radiation-induced intestinal inflammatory damage. Int. J. Cancer. 96:99-109.
30. Xia, L., M. Sperandio, T. Yago, J.M. McDaniel, R.D. Cummings, S. Pearson-White, K. Ley, and R.P. McEver. 2002. P-selectin glycoprotein ligand-1-deficient mice have impaired leukocyte tethering to E-selectin under flow. J. Clin. Invest. 109:939-950.
31. Iezzi, G., D. Scheidegger, and A. Lanzavecchia. 2001. Migration and function of antigen-primed nonpolarized T lymphocytes in vivo. J. Exp. Med. 193:987-993.
32. Fulton, S.A., J.M. Johnsen, S.F. Wolf, D.S. Sieburth, and W.H. Boom. 1996. Interleukin-12 production by human monocytes infected with Mycobacterium tuberculosis: role of phagocytosis. Infect. Immun. 64:2523-2531.
33. Cowdery, J.S., N.J. Boerth, L.A. Norian, P.S. Myung, and G.A. Koretzky. 1999. Differential regulation of the IL-12 p40 promoter and of p40 secretion by CpG DNA and lipopolysaccharide. J. Immunol. 162:6770-6775.