Granzyme M: Characterization with sites of post-translational modification and specific sites of interaction with substrates and inhibitors

Molecular Biology Reports

Volumn 38, Issue 5, 2011, Pages 2953-2960

  Khurshid, Rukhshan ^a   Saleem, Mahjabeen ^b   Akhtar, Muhammad Saleem ^c   Salim, Asmat ^d  

^a FATIMA JINNAH MEDICAL COLLEGE   (Pakistan)

^b UNIVERSITY OF THE PUNJAB   (Pakistan)

^c GC UNIVERSITY   (Pakistan)

^d UNIVERSITY OF KARACHI   (Pakistan)

Author keywords

Apoptosis; Gzm M; Inhibitor; Post translational modification

Indexed keywords

ENZYME INHIBITOR; GLYCINE; GRANZYME; GRANZYME M; PEPTIDE CHLOROMETHYL KETONE; PEPTIDE CHLOROMETHYL KETONE INHIBITOR; SERINE; THREONINE; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CELL SURFACE; CELLULAR DISTRIBUTION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME GLYCOSYLATION; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME SPECIFICITY; MOLECULAR MODEL; MYRISTYLATION; NATURAL KILLER CELL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN STABILITY; PROTEIN TRANSPORT; REGULATORY MECHANISM; STRUCTURE ACTIVITY RELATION;

APOPTOSIS; BINDING SITES; GRANZYMES; HUMANS; HYDROGEN BONDING; ISOENZYMES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; SERINE PROTEINASE INHIBITORS; SUBSTRATE SPECIFICITY;

EID: 80052475714     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-010-9959-7     Document Type: Article

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