Granzyme B binds to target cells mostly by charge and must be added at the same time as perforin to trigger apoptosis

Journal of Immunology

Volumn 174, Issue 9, 2005, Pages 5456-5461

  Shi, Lianfa ^a,b   Keefe, Dennis ^a   Durand, Enrique ^a   Feng, Hanping ^a   Zhang, Dong ^a   Lieberman, Judy ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b CENTER FOR BLOOD RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GRANZYME B; PERFORIN; SODIUM CHLORIDE;

APOPTOSIS; ARTICLE; CELL MEMBRANE; CELL SURFACE; CHEMICAL BOND; CONTROLLED STUDY; CYTOSOL; DISEASE MODEL; ENDOCYTOSIS; ENDOSOME; HUMAN; HUMAN CELL; IMMUNOSURVEILLANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN TRANSPORT; SYNAPSE; TARGET CELL; VALIDATION PROCESS; VIRUS INFECTION;

EID: 17844380811     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.174.9.5456     Document Type: Article

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