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Volumn 21, Issue 3, 2006, Pages 241-252

An assessment of the potential developmental and reproductive toxicity of di-isoheptyl phthalate in rodents

Author keywords

Developmental toxicity; Di isoheptyl phthalate; DIHP; Phthalate; Reproductive toxicity

Indexed keywords

PHTHALIC ACID BIS(5 METHYLHEXYL) ESTER; PHTHALIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

EID: 33644520283     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2005.09.002     Document Type: Article
Times cited : (43)

References (75)
  • 1
    • 0041304140 scopus 로고    scopus 로고
    • Esters of aromatic mono-, di-, and tricarboxylic acids, aromatic diacids, and di-, tri-, or polyalcohols
    • E. Bingham B. Cohrssen C. Powell 5th ed. John Wiley and Sons New York
    • R. David, R. McKee, J. Butala, R. Barter, and M. Kayser Esters of aromatic mono-, di-, and tricarboxylic acids, aromatic diacids, and di-, tri-, or polyalcohols E. Bingham B. Cohrssen C. Powell Patty's toxicology 5th ed. 2001 John Wiley and Sons New York 635 932
    • (2001) Patty's Toxicology , pp. 635-932
    • David, R.1    McKee, R.2    Butala, J.3    Barter, R.4    Kayser, M.5
  • 2
    • 0032859383 scopus 로고    scopus 로고
    • Evaluation of skin sensitization response of dialkyl (C6-C13) phthalate esters
    • A. Medeiros, D. Devlin, and L. Keller Evaluation of skin sensitization response of dialkyl (C6-C13) phthalate esters Contact Dermat 41 1999 287 289
    • (1999) Contact Dermat , vol.41 , pp. 287-289
    • Medeiros, A.1    Devlin, D.2    Keller, L.3
  • 3
    • 0032418291 scopus 로고    scopus 로고
    • Examination of the in vitro and in vivo estrogenic activities of eight phthalate esters
    • T. Zacharewski, M. Meek, J. Clemons, Z. Wu, M. Fielden, and J. Matthews Examination of the in vitro and in vivo estrogenic activities of eight phthalate esters Toxicol Sci 46 1998 282 293
    • (1998) Toxicol Sci , vol.46 , pp. 282-293
    • Zacharewski, T.1    Meek, M.2    Clemons, J.3    Wu, Z.4    Fielden, M.5    Matthews, J.6
  • 4
    • 0034038221 scopus 로고    scopus 로고
    • Comparative in vivo hepatic effects of di-isononyl phthalate (DINP) and related C7-C11 dialkyl phthalates on gap junctional intercellular communication (GJIC), peroxisomal beta-oxidation (PBOX), and DNA synthesis in rat and mouse liver
    • J. Smith, J. Isenberg, G. Pugh, L. Kamendulis, D. Ackley, and A. Lington Comparative in vivo hepatic effects of di-isononyl phthalate (DINP) and related C7-C11 dialkyl phthalates on gap junctional intercellular communication (GJIC), peroxisomal beta-oxidation (PBOX), and DNA synthesis in rat and mouse liver Toxicol Sci 54 2000 312 321
    • (2000) Toxicol Sci , vol.54 , pp. 312-321
    • Smith, J.1    Isenberg, J.2    Pugh, G.3    Kamendulis, L.4    Ackley, D.5    Lington, A.6
  • 5
    • 8444220827 scopus 로고    scopus 로고
    • Activation of mouse and human peroxisome proliferator-activated receptors (PPARs) by phthalate monoesters
    • M. Bililty, J. Thompson, R. McKee, R. David, J. Butala, and J. Vanden Heuvel Activation of mouse and human peroxisome proliferator-activated receptors (PPARs) by phthalate monoesters Toxicol Sci 82 2004 170 182
    • (2004) Toxicol Sci , vol.82 , pp. 170-182
    • Bililty, M.1    Thompson, J.2    McKee, R.3    David, R.4    Butala, J.5    Vanden Heuvel, J.6
  • 6
    • 0036756190 scopus 로고    scopus 로고
    • NTP Center for the Evaluation of Risks to Human Reproduction: Phthalates expert panel report on the reproductive and developmental toxicity of butyl benzyl phthalate
    • R. Kavlock, K. Boekelheide, R. Chapin, M. Cunningham, E. Faustman, and P. Foster NTP Center for the Evaluation of Risks to Human Reproduction: phthalates expert panel report on the reproductive and developmental toxicity of butyl benzyl phthalate Reprod Toxicol 16 2002 453 487
    • (2002) Reprod Toxicol , vol.16 , pp. 453-487
    • Kavlock, R.1    Boekelheide, K.2    Chapin, R.3    Cunningham, M.4    Faustman, E.5    Foster, P.6
  • 7
    • 0036754969 scopus 로고    scopus 로고
    • NTP Center for the Evaluation of Risks to Human Reproduction: Phthalates expert panel report on the reproductive and developmental toxicity of di-n-butyl phthalate
    • R. Kavlock, K. Boekelheide, R. Chapin, M. Cunningham, E. Faustman, and P. Foster NTP Center for the Evaluation of Risks to Human Reproduction: phthalates expert panel report on the reproductive and developmental toxicity of di-n-butyl phthalate Reprod Toxicol 16 2002 489 527
    • (2002) Reprod Toxicol , vol.16 , pp. 489-527
    • Kavlock, R.1    Boekelheide, K.2    Chapin, R.3    Cunningham, M.4    Faustman, E.5    Foster, P.6
  • 8
    • 0036755741 scopus 로고    scopus 로고
    • NTP Center for the Evaluation of Risks to Human Reproduction: Phthalates expert panel report on the reproductive and developmental toxicity of di(2-ethylhexyl phthalate)
    • R. Kavlock, K. Boekelheide, R. Chapin, M. Cunningham, E. Faustman, and P. Foster NTP Center for the Evaluation of Risks to Human Reproduction: phthalates expert panel report on the reproductive and developmental toxicity of di(2-ethylhexyl phthalate) Reprod Toxicol 16 2002 529 653
    • (2002) Reprod Toxicol , vol.16 , pp. 529-653
    • Kavlock, R.1    Boekelheide, K.2    Chapin, R.3    Cunningham, M.4    Faustman, E.5    Foster, P.6
  • 9
    • 0036754969 scopus 로고    scopus 로고
    • NTP Center for the Evaluation of Risks to Human Reproduction: Phthalates expert panel report on the reproductive and developmental toxicity of di-isodecyl phthalate
    • R. Kavlock, K. Boekelheide, R. Chapin, M. Cunningham, E. Faustman, and P. Foster NTP Center for the Evaluation of Risks to Human Reproduction: phthalates expert panel report on the reproductive and developmental toxicity of di-isodecyl phthalate Reprod Toxicol 16 2002 655 678
    • (2002) Reprod Toxicol , vol.16 , pp. 655-678
    • Kavlock, R.1    Boekelheide, K.2    Chapin, R.3    Cunningham, M.4    Faustman, E.5    Foster, P.6
  • 10
    • 0036754969 scopus 로고    scopus 로고
    • NTP Center for the Evaluation of Risks to Human Reproduction: Phthalates expert panel report on the reproductive and developmental toxicity of di-isononyl phthalate
    • R. Kavlock, K. Boekelheide, R. Chapin, M. Cunningham, E. Faustman, and P. Foster NTP Center for the Evaluation of Risks to Human Reproduction: phthalates expert panel report on the reproductive and developmental toxicity of di-isononyl phthalate Reprod Toxicol 16 2002 679 708
    • (2002) Reprod Toxicol , vol.16 , pp. 679-708
    • Kavlock, R.1    Boekelheide, K.2    Chapin, R.3    Cunningham, M.4    Faustman, E.5    Foster, P.6
  • 11
    • 0036755741 scopus 로고    scopus 로고
    • NTP Center for the Evaluation of Risks to Human Reproduction: Phthalates expert panel report on the reproductive and developmental toxicity of di-n-hexyl phthalate
    • R. Kavlock, K. Boekelheide, R. Chapin, M. Cunningham, E. Faustman, and P. Foster NTP Center for the Evaluation of Risks to Human Reproduction: phthalates expert panel report on the reproductive and developmental toxicity of di-n-hexyl phthalate Reprod Toxicol 16 2002 709 719
    • (2002) Reprod Toxicol , vol.16 , pp. 709-719
    • Kavlock, R.1    Boekelheide, K.2    Chapin, R.3    Cunningham, M.4    Faustman, E.5    Foster, P.6
  • 12
    • 0036754969 scopus 로고    scopus 로고
    • NTP Center for the Evaluation of Risks to Human Reproduction: Phthalates expert panel report on the reproductive and developmental toxicity of di-n-octyl phthalate
    • R. Kavlock, K. Boekelheide, R. Chapin, M. Cunningham, E. Faustman, and P. Foster NTP Center for the Evaluation of Risks to Human Reproduction: phthalates expert panel report on the reproductive and developmental toxicity of di-n-octyl phthalate Reprod Toxicol 16 2002 721 734
    • (2002) Reprod Toxicol , vol.16 , pp. 721-734
    • Kavlock, R.1    Boekelheide, K.2    Chapin, R.3    Cunningham, M.4    Faustman, E.5    Foster, P.6
  • 13
    • 0034523473 scopus 로고    scopus 로고
    • Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat
    • L. Gray, J. Ostby, J. Furr, M. Price, D. Veeramachaneni, and L. Parks Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat Toxicol Sci 58 2000 350 365
    • (2000) Toxicol Sci , vol.58 , pp. 350-365
    • Gray, L.1    Ostby, J.2    Furr, J.3    Price, M.4    Veeramachaneni, D.5    Parks, L.6
  • 14
    • 0031860360 scopus 로고    scopus 로고
    • Male reproductive tract malformations in rats following gestational and lactational exposure to di(n-butyl) phthalate: An antiandrogenic mechanism?
    • E. Mylchreest, R. Cattley, and P. Foster Male reproductive tract malformations in rats following gestational and lactational exposure to di(n-butyl) phthalate: an antiandrogenic mechanism? Toxicol Sci 43 1998 47 60
    • (1998) Toxicol Sci , vol.43 , pp. 47-60
    • Mylchreest, E.1    Cattley, R.2    Foster, P.3
  • 15
    • 0033010382 scopus 로고    scopus 로고
    • Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide
    • E. Mylchreest, M. Sar, R. Cattley, and P. Foster Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide Toxicol Appl Pharmacol 156 1999 81 95
    • (1999) Toxicol Appl Pharmacol , vol.156 , pp. 81-95
    • Mylchreest, E.1    Sar, M.2    Cattley, R.3    Foster, P.4
  • 16
    • 0035045792 scopus 로고    scopus 로고
    • Abnormalities of sexual development in male rats with in utero and lactational exposure to the antiandrogenic plasticizer di(2-ethylhexyl) phthalate
    • R. Moore, T. Rudy, T. Lin, K. Ko, and R. Peterson Abnormalities of sexual development in male rats with in utero and lactational exposure to the antiandrogenic plasticizer di(2-ethylhexyl) phthalate Environ Health Perspect 109 2001 229 237
    • (2001) Environ Health Perspect , vol.109 , pp. 229-237
    • Moore, R.1    Rudy, T.2    Lin, T.3    Ko, K.4    Peterson, R.5
  • 17
    • 0034521058 scopus 로고    scopus 로고
    • The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat
    • L. Parks, J. Ostby, C. Lambright, B. Abbott, G. Klinefelter, and N. Barlow The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat Toxicol Sci 58 2000 339 349
    • (2000) Toxicol Sci , vol.58 , pp. 339-349
    • Parks, L.1    Ostby, J.2    Lambright, C.3    Abbott, B.4    Klinefelter, G.5    Barlow, N.6
  • 19
    • 0030887391 scopus 로고    scopus 로고
    • Reproductive assessment by continuous breeding: Evolving study design and summaries of ninety studies
    • R. Chapin, and R. Sloane Reproductive assessment by continuous breeding: evolving study design and summaries of ninety studies Environ Health Perspect 105 1997 199 258
    • (1997) Environ Health Perspect , vol.105 , pp. 199-258
    • Chapin, R.1    Sloane, R.2
  • 25
    • 0003064131 scopus 로고
    • Detection of visceral alterations in mammalian fetus
    • R. Staples Detection of visceral alterations in mammalian fetus Teratology 9 1974 A-37
    • (1974) Teratology , vol.9 , pp. 37
    • Staples, R.1
  • 26
    • 0021637726 scopus 로고
    • Fresh visceral examination of rat and rabbit fetuses used in teratogenicity testing
    • J. Stuckhardt, and S. Poppe Fresh visceral examination of rat and rabbit fetuses used in teratogenicity testing Teratol Carcinogen Mutagen 4 1984 181 188
    • (1984) Teratol Carcinogen Mutagen , vol.4 , pp. 181-188
    • Stuckhardt, J.1    Poppe, S.2
  • 28
    • 0002709595 scopus 로고
    • One way classifications: Analysis of variance
    • 7th ed. The Iowa State University Press Ames, IA
    • G. Snedecor, and W. Cochran One way classifications: analysis of variance Statistical methods 7th ed. 1989 The Iowa State University Press Ames, IA p. 215-37
    • (1989) Statistical Methods
    • Snedecor, G.1    Cochran, W.2
  • 29
    • 0000080398 scopus 로고
    • New tables for multiple comparisons with a control
    • C. Dunnett New tables for multiple comparisons with a control Biometrics 20 1964 482 491
    • (1964) Biometrics , vol.20 , pp. 482-491
    • Dunnett, C.1
  • 35
    • 0017622991 scopus 로고
    • Preputial separation as an external sign of pubertal development in the male rat
    • C. Korenbrot, I. Huhtaniemi, and R. Weiner Preputial separation as an external sign of pubertal development in the male rat Biol Reprod 17 1977 298 303
    • (1977) Biol Reprod , vol.17 , pp. 298-303
    • Korenbrot, C.1    Huhtaniemi, I.2    Weiner, R.3
  • 37
    • 0027032045 scopus 로고
    • Endpoints of spermatotoxicity in the rat after short duration exposures to fourteen reproductive toxicants
    • R. Linder, L. Strader, V. Slott, and J. Suarez Endpoints of spermatotoxicity in the rat after short duration exposures to fourteen reproductive toxicants Reprod Toxicol 6 1992 491 505
    • (1992) Reprod Toxicol , vol.6 , pp. 491-505
    • Linder, R.1    Strader, L.2    Slott, V.3    Suarez, J.4
  • 38
    • 0022386071 scopus 로고
    • Potential indicators of reproductive toxicity: Testicular sperm production and epididymal sperm number, transit time and motility in Fischer 344 rats
    • W. Blazak, T. Ernst, and B. Stewart Potential indicators of reproductive toxicity: testicular sperm production and epididymal sperm number, transit time and motility in Fischer 344 rats Fundam Appl Toxicol 5 1985 1097 1103
    • (1985) Fundam Appl Toxicol , vol.5 , pp. 1097-1103
    • Blazak, W.1    Ernst, T.2    Stewart, B.3
  • 39
    • 0030669383 scopus 로고    scopus 로고
    • Differential follicle counts as a screen for chemically induced ovarian toxicity in mice: Results from continuous breeding bioassays
    • B. Bolon, T. Bucci, A. Warbritton, J. Chen, D. Mattison, and J. Heindel Differential follicle counts as a screen for chemically induced ovarian toxicity in mice: results from continuous breeding bioassays Fundam Appl Toxicol 39 1997 1 10
    • (1997) Fundam Appl Toxicol , vol.39 , pp. 1-10
    • Bolon, B.1    Bucci, T.2    Warbritton, A.3    Chen, J.4    Mattison, D.5    Heindel, J.6
  • 40
    • 0031563526 scopus 로고    scopus 로고
    • Influence of sampling on the reproducibility of ovarian follicle counts in mouse toxicity studies
    • T. Bucci, B. Bolon, A. Warbritton, J. Chen, and J. Heindel Influence of sampling on the reproducibility of ovarian follicle counts in mouse toxicity studies Reprod Toxicol 11 1997 689 696
    • (1997) Reprod Toxicol , vol.11 , pp. 689-696
    • Bucci, T.1    Bolon, B.2    Warbritton, A.3    Chen, J.4    Heindel, J.5
  • 41
    • 0001067751 scopus 로고
    • General class of covariance structures for two or more repeated factors in longitudinal data analysis
    • A. Galecki General class of covariance structures for two or more repeated factors in longitudinal data analysis Commun Stat Theory Methods 23 1994 3105 3119
    • (1994) Commun Stat Theory Methods , vol.23 , pp. 3105-3119
    • Galecki, A.1
  • 43
    • 84943709252 scopus 로고
    • Use of ranks in one-criterion variance analysis
    • W. Kruskal, and W. Wallis Use of ranks in one-criterion variance analysis J Am Stat Assoc 47 1952 583 621
    • (1952) J Am Stat Assoc , vol.47 , pp. 583-621
    • Kruskal, W.1    Wallis, W.2
  • 45
    • 0027948537 scopus 로고
    • Di(2-ethylhexyl) phthalate suppresses estradiol and ovulation in cycling rats
    • B. Davis, R. Maronpot, and J. Heindel Di(2-ethylhexyl) phthalate suppresses estradiol and ovulation in cycling rats Toxicol Appl Pharmacol 128 1994 216 223
    • (1994) Toxicol Appl Pharmacol , vol.128 , pp. 216-223
    • Davis, B.1    Maronpot, R.2    Heindel, J.3
  • 46
    • 0035341453 scopus 로고    scopus 로고
    • Mono-(2-ethylhexyl) phthalate suppresses aromatase transcript levels and estradiol production in cultured rat granulosa cells
    • T. Lovekamp, and B. Davis Mono-(2-ethylhexyl) phthalate suppresses aromatase transcript levels and estradiol production in cultured rat granulosa cells Toxicol Appl Pharmacol 172 2001 217 224
    • (2001) Toxicol Appl Pharmacol , vol.172 , pp. 217-224
    • Lovekamp, T.1    Davis, B.2
  • 47
    • 0037295361 scopus 로고    scopus 로고
    • Mechanisms of phthalate ester toxicity in the female reproductive biosystem
    • T. Lovekamp-Swan, and B. Davis Mechanisms of phthalate ester toxicity in the female reproductive biosystem Environ Health Perspect 111 2002 139 145
    • (2002) Environ Health Perspect , vol.111 , pp. 139-145
    • Lovekamp-Swan, T.1    Davis, B.2
  • 48
    • 0037471230 scopus 로고    scopus 로고
    • Dual activation of PPAR α and PPAR γ by mono-(2-ethylhexyl) phthalate in rat ovarian granulosa cells
    • T. Lovekamp, A. Jetten, and B. Davis Dual activation of PPAR α and PPAR γ by mono-(2-ethylhexyl) phthalate in rat ovarian granulosa cells Mol Cell Endocrinol 201 2003 133 141
    • (2003) Mol Cell Endocrinol , vol.201 , pp. 133-141
    • Lovekamp, T.1    Jetten, A.2    Davis, B.3
  • 49
    • 0032168185 scopus 로고    scopus 로고
    • Further evaluation of developmental toxicity of di-n-butyl phthalate following administration during late pregnancy in rats
    • M. Ema, E. Miyawaki, and K. Kawashima Further evaluation of developmental toxicity of di-n-butyl phthalate following administration during late pregnancy in rats Toxicol Lett 98 1998 87 93
    • (1998) Toxicol Lett , vol.98 , pp. 87-93
    • Ema, M.1    Miyawaki, E.2    Kawashima, K.3
  • 50
    • 0033989741 scopus 로고    scopus 로고
    • Critical period for adverse effects on development of reproductive system in male offspring of rats given di-n-butyl phthalate during late pregnancy
    • M. Ema, E. Miyawaki, and K. Kawashima Critical period for adverse effects on development of reproductive system in male offspring of rats given di-n-butyl phthalate during late pregnancy Toxicol Lett 111 2000 271 278
    • (2000) Toxicol Lett , vol.111 , pp. 271-278
    • Ema, M.1    Miyawaki, E.2    Kawashima, K.3
  • 51
    • 0034021024 scopus 로고    scopus 로고
    • Dose-dependent alterations in androgen-regulated male reproductive development in rats exposed to di(n-butyl) phthalate during late gestation
    • E. Mylchreest, D. Wallace, R. Cattley, and P. Foster Dose-dependent alterations in androgen-regulated male reproductive development in rats exposed to di(n-butyl) phthalate during late gestation Toxicol Sci 55 2000 143 151
    • (2000) Toxicol Sci , vol.55 , pp. 143-151
    • Mylchreest, E.1    Wallace, D.2    Cattley, R.3    Foster, P.4
  • 52
    • 0842301865 scopus 로고    scopus 로고
    • Reproductive effects of di-butyl phthalate in Sprague-Dawley rats when assessed in a multigeneration study
    • R. Patel, G. Wolf, S. Rouselle, G. Cherian, K. Ko, and R. Moore Reproductive effects of di-butyl phthalate in Sprague-Dawley rats when assessed in a multigeneration study Toxicologist 60 2001 385
    • (2001) Toxicologist , vol.60 , pp. 385
    • Patel, R.1    Wolf, G.2    Rouselle, S.3    Cherian, G.4    Ko, K.5    Moore, R.6
  • 53
    • 0033653315 scopus 로고    scopus 로고
    • Effect of butyl benzyl phthalate in Sprague-Dawley rats after gavage administration: A two-generation reproductive study
    • T. Nagao, R. Ota, H. Marumo, T. Shindo, S. Yoshimura, and H. Ono Effect of butyl benzyl phthalate in Sprague-Dawley rats after gavage administration: a two-generation reproductive study Reprod Toxicol 14 2000 513 532
    • (2000) Reprod Toxicol , vol.14 , pp. 513-532
    • Nagao, T.1    Ota, R.2    Marumo, H.3    Shindo, T.4    Yoshimura, S.5    Ono, H.6
  • 54
    • 1542408707 scopus 로고    scopus 로고
    • Reproductive toxicity evaluation of dietary butyl benzyl phthalate in rats
    • R. Tyl, M. Myers, M. Marr, P. Fail, J. Seely, and D. Brine Reproductive toxicity evaluation of dietary butyl benzyl phthalate in rats Reprod Toxicol 18 2004 241 264
    • (2004) Reprod Toxicol , vol.18 , pp. 241-264
    • Tyl, R.1    Myers, M.2    Marr, M.3    Fail, P.4    Seely, J.5    Brine, D.6
  • 55
    • 0842280082 scopus 로고    scopus 로고
    • Reproductive effects of diethylhexyl phthalate (DEHP) in Sprague-Dawley rats when assessed by the continuous breeding protocol
    • G. Wolfe, K. Layton, L. Nehrebeckyj, Y. Wang, R. Chapin, and S. Rousselle Reproductive effects of diethylhexyl phthalate (DEHP) in Sprague-Dawley rats when assessed by the continuous breeding protocol Toxicologist 66 2002 234
    • (2002) Toxicologist , vol.66 , pp. 234
    • Wolfe, G.1    Layton, K.2    Nehrebeckyj, L.3    Wang, Y.4    Chapin, R.5    Rousselle, S.6
  • 56
    • 0007261108 scopus 로고    scopus 로고
    • Reproduction toxicity of di-2-ethylhexyl phthalate (DEHP)
    • K. Shilling, C. Gembart, and J. Hellwig Reproduction toxicity of di-2-ethylhexyl phthalate (DEHP) Toxicologist 48 1999 147 148
    • (1999) Toxicologist , vol.48 , pp. 147-148
    • Shilling, K.1    Gembart, C.2    Hellwig, J.3
  • 57
    • 0036774846 scopus 로고    scopus 로고
    • Reproductive and neurobehavioral toxicity study of bis (2-ethylhexyl) phthalate (DEHP) administered to mice in the diet
    • T. Tanaka Reproductive and neurobehavioral toxicity study of bis (2-ethylhexyl) phthalate (DEHP) administered to mice in the diet Food Chem Toxicol 40 2002 1499 1506
    • (2002) Food Chem Toxicol , vol.40 , pp. 1499-1506
    • Tanaka, T.1
  • 58
    • 0036010069 scopus 로고    scopus 로고
    • Fetal testosterone insufficiency and abnormal proliferation of Leydig cells and gonocytes in rats exposed to di(n-butyl) phthalate
    • E. Mylchreest, M. Sar, D. Wallace, and P. Foster Fetal testosterone insufficiency and abnormal proliferation of Leydig cells and gonocytes in rats exposed to di(n-butyl) phthalate Reprod Toxicol 16 2002 19 28
    • (2002) Reprod Toxicol , vol.16 , pp. 19-28
    • Mylchreest, E.1    Sar, M.2    Wallace, D.3    Foster, P.4
  • 59
    • 0036286837 scopus 로고    scopus 로고
    • Effect of peroxisome proliferators on Leydig cell peripheral-type benzodiazepine receptor gene expression, hormone-stimulated cholesterol transport, and steroidogenesis: Role of the peroxisome proliferator-activator receptor α
    • M. Gazouli, Z. Yao, N. Boujrad, J. Corton, M. Culty, and V. Papadopoulos Effect of peroxisome proliferators on Leydig cell peripheral-type benzodiazepine receptor gene expression, hormone-stimulated cholesterol transport, and steroidogenesis: role of the peroxisome proliferator-activator receptor α Endocrinology 143 2002 2571 2583
    • (2002) Endocrinology , vol.143 , pp. 2571-2583
    • Gazouli, M.1    Yao, Z.2    Boujrad, N.3    Corton, J.4    Culty, M.5    Papadopoulos, V.6
  • 60
    • 0035194978 scopus 로고    scopus 로고
    • Altered gene profiles in fetal rat testes after in utero exposure to di(n-butyl) phthalate
    • V. Shultz, S. Phillips, M. Sar, P. Foster, and K. Gaido Altered gene profiles in fetal rat testes after in utero exposure to di(n-butyl) phthalate Toxicol Sci 64 2001 233 242
    • (2001) Toxicol Sci , vol.64 , pp. 233-242
    • Shultz, V.1    Phillips, S.2    Sar, M.3    Foster, P.4    Gaido, K.5
  • 61
    • 0037497143 scopus 로고    scopus 로고
    • Quantitative changes in gene expression in fetal rat testes following exposure to di(n-butyl) phthalate
    • N. Barlow, S. Phillips, D. Wallace, M. Sar, K. Gaido, and P. Foster Quantitative changes in gene expression in fetal rat testes following exposure to di(n-butyl) phthalate Toxicol Sci 73 2003 431 441
    • (2003) Toxicol Sci , vol.73 , pp. 431-441
    • Barlow, N.1    Phillips, S.2    Wallace, D.3    Sar, M.4    Gaido, K.5    Foster, P.6
  • 62
    • 4444242509 scopus 로고    scopus 로고
    • Dose-dependent alterations in gene expression and testosterone synthesis in the fetal testes of male rats exposed to di(n-butyl) phthalate
    • K. Lehmann, S. Phillips, M. Sar, P. Foster, and K. Gaido Dose-dependent alterations in gene expression and testosterone synthesis in the fetal testes of male rats exposed to di(n-butyl) phthalate Toxicol Sci 81 2004 60 68
    • (2004) Toxicol Sci , vol.81 , pp. 60-68
    • Lehmann, K.1    Phillips, S.2    Sar, M.3    Foster, P.4    Gaido, K.5
  • 63
    • 33644527464 scopus 로고    scopus 로고
    • Identification of gene clusters and signalling pathways affected by dibutyl phthalate - Nuclear receptor interactions in foetal rat testes
    • S. Plummer, N. Hallmark, R. Sharpe, and C. Elcombe Identification of gene clusters and signalling pathways affected by dibutyl phthalate - nuclear receptor interactions in foetal rat testes Toxicologist 84 2005 220
    • (2005) Toxicologist , vol.84 , pp. 220
    • Plummer, S.1    Hallmark, N.2    Sharpe, R.3    Elcombe, C.4
  • 64
    • 0346366559 scopus 로고    scopus 로고
    • Phthalate-ester-induced gubernacular lesions are associated with reduced insl3 gene expression in the fetal rat testis
    • V. Wilson, C. Lambright, J. Furr, J. Ostby, C. Wood, and G. Held Phthalate-ester-induced gubernacular lesions are associated with reduced insl3 gene expression in the fetal rat testis Toxicol Lett 146 2004 207 215
    • (2004) Toxicol Lett , vol.146 , pp. 207-215
    • Wilson, V.1    Lambright, C.2    Furr, J.3    Ostby, J.4    Wood, C.5    Held, G.6
  • 65
    • 4444300142 scopus 로고    scopus 로고
    • Cracking the nut
    • K. Boekelheide Cracking the nut Toxicol Sci 81 2004 1 2
    • (2004) Toxicol Sci , vol.81 , pp. 1-2
    • Boekelheide, K.1
  • 66
    • 77957177999 scopus 로고
    • Dermal absorption of phthalate diesters in rats
    • A. Elsisi, D. Carter, and I. Sipes Dermal absorption of phthalate diesters in rats Fundam Appl Toxicol 12 1989 70 77
    • (1989) Fundam Appl Toxicol , vol.12 , pp. 70-77
    • Elsisi, A.1    Carter, D.2    Sipes, I.3
  • 68
    • 1542686315 scopus 로고    scopus 로고
    • Urinary levels of seven phthalate metabolites in the U.S. population from the National Health and Nutrition Examination Survey (NHANES) 1999-2000
    • M. Silva, D. Barr, J. Reidy, N. Malek, C. Hodge, and S. Caudill Urinary levels of seven phthalate metabolites in the U.S. population from the National Health and Nutrition Examination Survey (NHANES) 1999-2000 Environ Health Perspect 112 2004 331 338
    • (2004) Environ Health Perspect , vol.112 , pp. 331-338
    • Silva, M.1    Barr, D.2    Reidy, J.3    Malek, N.4    Hodge, C.5    Caudill, S.6
  • 69
    • 17444434943 scopus 로고    scopus 로고
    • Exposure to phthalate esters
    • R. David Exposure to phthalate esters Environ Health Perspect 108 2000 A440
    • (2000) Environ Health Perspect , vol.108 , pp. 440
    • David, R.1
  • 71
    • 0842328577 scopus 로고    scopus 로고
    • NTP Center for the Evaluation of Risks to Human Reproduction reports on phthalates: Addressing the data gaps
    • R. McKee, J. Butala, R. David, and G. Gans NTP Center for the Evaluation of Risks to Human Reproduction reports on phthalates: addressing the data gaps Reprod Toxicol 18 2004 1 22
    • (2004) Reprod Toxicol , vol.18 , pp. 1-22
    • McKee, R.1    Butala, J.2    David, R.3    Gans, G.4
  • 73
    • 14644401703 scopus 로고    scopus 로고
    • Plastics additives in the indoor environment - Flame retardants and plasticizers
    • M. Wensing, E. Uhde, and T. Salthammer Plastics additives in the indoor environment - flame retardants and plasticizers Sci Total Environ 339 2005 19 40
    • (2005) Sci Total Environ , vol.339 , pp. 19-40
    • Wensing, M.1    Uhde, E.2    Salthammer, T.3
  • 74
    • 1842627957 scopus 로고    scopus 로고
    • Distribution of phthalate esters in a marine aquatic food web: Comparison to polychlorinated biphenyls
    • C. Mackintosh, J. Maldonado, J. Hongwu, N. Hoover, A. Chong, and M. Ikonomou Distribution of phthalate esters in a marine aquatic food web: comparison to polychlorinated biphenyls Environ Sci Technol 38 2004 2011 2020
    • (2004) Environ Sci Technol , vol.38 , pp. 2011-2020
    • MacKintosh, C.1    Maldonado, J.2    Hongwu, J.3    Hoover, N.4    Chong, A.5    Ikonomou, M.6
  • 75


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.