Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat

Toxicological Sciences

Volumn 58, Issue 2, 2000, Pages 350-365

  Gray Jr , L Earl ^a   Ostby, Joseph ^a   Furr, Johnathan ^a   Price, Matthew ^a   Veeramachaneni, D N Rao ^b   Parks, Louise ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Abnormal sexual differentiation; BBP; DEHP; DEP; DINP; DMP; DOTP; Hypospadias; Phthalates; Risk assessment

Indexed keywords

BENZYL DERIVATIVE; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; PHTHALIC ACID DERIVATIVE; PHTHALIC ACID DIETHYL ESTER; PHTHALIC ACID DIMETHYL ESTER; PHTHALIC ACID DIOCTYL ESTER; TEREPHTHALIC ACID; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIRTH WEIGHT; BREAST AREOLA; CHEMICAL STRUCTURE; CONTROLLED STUDY; EXPOSURE; FEMALE; GENDER; GENITAL MALFORMATION; INFANCY; LITTER SIZE; MALE; NIPPLE; NONHUMAN; PERINATAL PERIOD; PREGNANCY; RAT; RAT STRAIN; SEX DIFFERENTIATION DISORDER; TESTIS WEIGHT; TESTOSTERONE BLOOD LEVEL; WEIGHT GAIN;

ABNORMALITIES, DRUG-INDUCED; ANDROGEN ANTAGONISTS; ANIMALS; DIETHYLHEXYL PHTHALATE; FEMALE; FETUS; HUMANS; MALE; PHTHALIC ACIDS; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; SEX DIFFERENTIATION; SEXUAL BEHAVIOR, ANIMAL; SPECIES SPECIFICITY;

ANIMALIA; MAMMALIA;

EID: 0034523473     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/58.2.350     Document Type: Article

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