A mixture of the "antiandrogens" linuron and butyl benzyl phthalate alters sexual differentiation of the male rat in a cumulative fashion

Biology of Reproduction

Volumn 71, Issue 6, 2004, Pages 1852-1861

  Hotchkiss, A K ^a   Parks Saldutti, L G ^b,d   Ostby, J S ^b   Lambright, C ^b   Furr, J ^b   Vandenbergh, J G ^a   Gray Jr , L Earl ^b,c  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^d MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Androgen receptor; Male reproductive tract; Male sexual function; Testosterone; Toxicology

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; ANTIANDROGEN; CORN OIL; LINURON; PHTHALIC ACID BENZYL BUTYL ESTER; PROGESTERONE; TESTOSTERONE;

ANIMAL CELL; ANIMAL TISSUE; ANOGENITAL DISTANCE; ANUS; ARTICLE; BREAST AREOLA; COHORT ANALYSIS; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MIXTURE; DRUG POTENTIATION; FETUS; GENITAL MALFORMATION; GENITAL SYSTEM; JUVENILE AREOLA NUMBER; MALE; MALE GENITAL SYSTEM; NIPPLE MALFORMATION; NONHUMAN; PREGNANCY; PRENATAL DRUG EXPOSURE; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROGENY; PROGESTERONE SYNTHESIS; RAT; REPRODUCTIVE TOXICITY; SEX DIFFERENTIATION; SEXUAL FUNCTION; SIGNAL TRANSDUCTION; TESTOSTERONE SYNTHESIS;

ANAL CANAL; ANDROGEN ANTAGONISTS; ANIMALS; ANIMALS, NEWBORN; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FETUS; GENITALIA, MALE; LINURON; MALE; OSMOLAR CONCENTRATION; PHTHALIC ACIDS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROGESTERONE; RATS; RATS, SPRAGUE-DAWLEY; SEX DIFFERENTIATION; TESTIS; TESTOSTERONE;

ANIMALIA; ZEA MAYS;

EID: 9744248326     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.104.031674     Document Type: Article

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