메뉴 건너뛰기




Volumn 118, Issue 9, 2011, Pages 2395-2404

Blood doping and its detection

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; CNTO 528; CNTO 530; COBALT; ERYTHROPOIETIN; GROWTH HORMONE; HEMOGLOBIN; HYBRID PROTEIN; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; PEGISENATIDE; PROSTANOID; RECOMBINANT ERYTHROPOIETIN; TESTOSTERONE; THYROID HORMONE; UNCLASSIFIED DRUG;

EID: 80052423299     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-02-303271     Document Type: Review
Times cited : (124)

References (125)
  • 1
    • 80052398835 scopus 로고    scopus 로고
    • Accessed February 2011
    • World Anti-Doping Agency. http://www.wada-ama.org/en. Accessed February 2011.
  • 2
    • 84878643090 scopus 로고    scopus 로고
    • Accessed February 2011
    • World Anti-Doping Agency. Athlete Biological Passport Operating Guidelines. http://www.wada-ama.org/en/Science-Medicine/Athlete-Biological- Passport/Operating-Guidelines. Accessed February 2011.
    • Athlete Biological Passport Operating Guidelines
  • 3
    • 21744454489 scopus 로고    scopus 로고
    • Hematologic disorders in the athlete
    • DOI 10.1016/j.csm.2005.03.006, PII S0278591905000128, Trainig Room Management of Medical Conditions
    • Mercer K.W., Densmore J.J. Hematologic disorders in the athlete. Clin Sports Med. 2005;24(3):599-621. (Pubitemid 40943418)
    • (2005) Clinics in Sports Medicine , vol.24 , Issue.3 , pp. 599-621
    • Mercer, K.W.1    Densmore, J.J.2
  • 4
    • 33646858599 scopus 로고    scopus 로고
    • Importance of hemoglobin concentration to exercise: Acute manipulations
    • DOI 10.1016/j.resp.2006.01.014, PII S1569904806000413
    • Calbet J.A., Lundby C., Koskolou M., Boushel R. Importance of hemoglobin concentration to exercise: Acute manipulations. Respir Physiol Neurobiol. 2006;151(2):132-140. (Pubitemid 43786162)
    • (2006) Respiratory Physiology and Neurobiology , vol.151 , Issue.2-3 , pp. 132-140
    • Calbet, J.A.L.1    Lundby, C.2    Koskolou, M.3    Boushel, R.4
  • 5
    • 0036016067 scopus 로고    scopus 로고
    • 2max with no history of training is primarily due to high blood volume
    • 2max with no history of training is primarily due to high blood volume. Med Sci Sports Exerc. 2002;34(6):966-971.
    • (2002) Med Sci Sports Exerc , vol.34 , Issue.6 , pp. 966-971
    • Martino, M.1    Gledhill, N.2    Jamnik, V.3
  • 6
    • 37049206935 scopus 로고
    • The effect of transfusions of red blood cells on the hypoxia tolerance of normal men
    • Pace N., Consolazio W.V., Lozner E.L. The effect of transfusions of red blood cells on the hypoxia tolerance of normal men. Science. 1945;102(2658):589-591.
    • (1945) Science. , vol.102 , Issue.2658 , pp. 589-591
    • Pace, N.1    Consolazio, W.V.2    Lozner, E.L.3
  • 8
    • 0033628379 scopus 로고    scopus 로고
    • Blood volume, aerobic power, and endurance performance: Potential ergogenic effect of volume loading
    • Warburton D.E., Gledhill N., Quinney H.A. Blood volume, aerobic power, and endurance performance: Potential ergogenic effect of volume loading. Clin J Sport Med. 2000;10(1):59-66.
    • (2000) Clin J Sport Med , vol.10 , Issue.1 , pp. 59-66
    • Warburton, D.E.1    Gledhill, N.2    Quinney, H.A.3
  • 10
    • 0025916623 scopus 로고
    • Effect of erythropoietin administration on maximal aerobic power in man
    • Ekblom B., Berglund B. Effect of erythropoietin administration on maximal aerobic power in man. Scand J Med Sci Sports. 1991;1(2):88-93.
    • (1991) Scand J Med Sci Sports , vol.1 , Issue.2 , pp. 88-93
    • Ekblom, B.1    Berglund, B.2
  • 11
    • 0025980449 scopus 로고
    • Effect of recombinant human erythropoietin treatment on blood pressure and some haematological parameters in healthy men
    • Berglund B., Ekblom B. Effect of recombinant human erythropoietin treatment on blood pressure and some haematological parameters in healthy men. J Intern Med. 1991;229(2):125-130.
    • (1991) J Intern Med. , vol.229 , Issue.2 , pp. 125-130
    • Berglund, B.1    Ekblom, B.2
  • 15
    • 79952589438 scopus 로고    scopus 로고
    • Effects of recombinant human erythropoietin in normal humans
    • Lundby C., Olsen N.V. Effects of recombinant human erythropoietin in normal humans. J Physiol. 2011;589(6):1265-1271.
    • (2011) J Physiol. , vol.589 , Issue.6 , pp. 1265-1271
    • Lundby, C.1    Olsen, N.V.2
  • 16
    • 53449094560 scopus 로고    scopus 로고
    • Does recombinant human Epo increase exercise capacity by means other than augmenting oxygen transport?
    • Lundby C., Robach P., Boushel R., et al. Does recombinant human Epo increase exercise capacity by means other than augmenting oxygen transport? J Appl Physiol. 2008;105(2):581-587.
    • (2008) J Appl Physiol. , vol.105 , Issue.2 , pp. 581-587
    • Lundby, C.1    Robach, P.2    Boushel, R.3
  • 17
    • 41949137980 scopus 로고    scopus 로고
    • Erythropoietin receptor in human skeletal muscle and the effects of acute and long-term injections with recombinant human erythropoietin on the skeletal muscle
    • DOI 10.1152/japplphysiol.01211.2007
    • Lundby C., Hellsten Y., Jensen M.B., Munch A.S., Pilegaard H. Erythropoietin receptor in human skeletal muscle and the effects of acute and long-term injections with recombinant human erythropoietin on the skeletal muscle. J Appl Physiol. 2008;104(4):1154-1160. (Pubitemid 351507957)
    • (2008) Journal of Applied Physiology , vol.104 , Issue.4 , pp. 1154-1160
    • Lundby, C.1    Hellsten, Y.2    Jensen, M.B.F.3    Munch, A.S.4    Pilegaard, H.5
  • 18
    • 77955594312 scopus 로고    scopus 로고
    • Effects of erythropoietin administration on cerebral metabolism and exercise capacity in men
    • Rasmussen P., Foged E.M., Krogh-Madsen R., et al. Effects of erythropoietin administration on cerebral metabolism and exercise capacity in men. J Appl Physiol. 2010;109(2):476-483.
    • (2010) J Appl Physiol. , vol.109 , Issue.2 , pp. 476-483
    • Rasmussen, P.1    Foged, E.M.2    Krogh-Madsen, R.3
  • 19
    • 0030763967 scopus 로고    scopus 로고
    • The effect of intravenous iron on the reticulocyte response to recombinant human erythropoietin
    • Major A., Mathez-Loic F., Rohling R., Gautschi K., Brugnara C. The effect of intravenous iron on the reticulocyte response to recombinant human erythropoietin. Br J Haematol. 1997;98(2):292-294. (Pubitemid 27345099)
    • (1997) British Journal of Haematology , vol.98 , Issue.2 , pp. 292-294
    • Major, A.1    Mathez-Loic, F.2    Rohling, R.3    Gautschi, K.4    Brugnara, C.5
  • 21
    • 0033949101 scopus 로고    scopus 로고
    • A global strategy for prevention and detection of blood doping with erythropoietin and related drugs
    • Cazzola M. A global strategy for prevention and detection of blood doping with erythropoietin and related drugs. Haematologica. 2000;85(6):561-563. (Pubitemid 30450933)
    • (2000) Haematologica , vol.85 , Issue.6 , pp. 561-563
    • Cazzola, M.1
  • 22
    • 0345686665 scopus 로고    scopus 로고
    • Proof of homologous blood transfusion through quantification of blood group antigens
    • Nelson M., Popp H., Sharpe K., Ashenden M. Proof of homologous blood transfusion through quantification of blood group antigens. Haematologica. 2003;88(11):1284-1295. (Pubitemid 37456384)
    • (2003) Haematologica , vol.88 , Issue.11 , pp. 1284-1295
    • Nelson, M.1    Popp, H.2    Sharpe, K.3    Ashenden, M.4
  • 23
    • 49949151948 scopus 로고    scopus 로고
    • Scientific and forensic standards for homologous blood transfusion anti-doping analyses
    • Giraud S., Robinson N., Mangin P., Saugy M. Scientific and forensic standards for homologous blood transfusion anti-doping analyses. Forensic Sci Int. 2008;179(1):23-33.
    • (2008) Forensic Sci Int. , vol.179 , Issue.1 , pp. 23-33
    • Giraud, S.1    Robinson, N.2    Mangin, P.3    Saugy, M.4
  • 26
    • 77953293060 scopus 로고    scopus 로고
    • A world apart: Inaccuracies of laboratory methodologies in antidoping testing
    • Banfi G., Lombardi G., Colombini A., Lippi G. A world apart: Inaccuracies of laboratory methodologies in antidoping testing. Clin Chim Acta. 2010;411(15):1003-1008.
    • (2010) Clin Chim Acta. , vol.411 , Issue.15 , pp. 1003-1008
    • Banfi, G.1    Lombardi, G.2    Colombini, A.3    Lippi, G.4
  • 27
    • 76449102304 scopus 로고    scopus 로고
    • Assessment of total haemoglobin mass: Can it detect erythropoietin- induced blood manipulations?
    • Lundby C., Robach P. Assessment of total haemoglobin mass: Can it detect erythropoietin-induced blood manipulations? Eur J Appl Physiol. 2010;108(1):197-200.
    • (2010) Eur J Appl Physiol. , vol.108 , Issue.1 , pp. 197-200
    • Lundby, C.1    Robach, P.2
  • 28
    • 77957723026 scopus 로고    scopus 로고
    • Biosimilar epoetins and other "follow-on" biologics: Update on the European experiences
    • Jelkmann W. Biosimilar epoetins and other "follow-on" biologics: Update on the European experiences. Am J Hematol. 2010;85(10):771-780.
    • (2010) Am J Hematol. , vol.85 , Issue.10 , pp. 771-780
    • Jelkmann, W.1
  • 29
    • 60149095565 scopus 로고    scopus 로고
    • Current and upcoming erythropoiesis-stimulating agents, iron products, and other novel anemia medications
    • Macdougall I.C., Ashenden M. Current and upcoming erythropoiesis- stimulating agents, iron products, and other novel anemia medications. Adv Chronic Kidney Dis. 2009;16(2):117-130.
    • (2009) Adv Chronic Kidney Dis. , vol.16 , Issue.2 , pp. 117-130
    • Macdougall, I.C.1    Ashenden, M.2
  • 30
    • 0037114935 scopus 로고    scopus 로고
    • Detection of isoelectric profiles of erythropoietin in urine: Differentiation of natural and administered recombinant hormones
    • DOI 10.1016/S0003-2697(02)00407-4, PII S0003269702004074
    • Lasne F., Martin L., Crepin N., De Ceaurriz J. Detection of isoelectric profiles of erythropoietin in urine: Differentiation of natural and administered recombinant hormones. Anal Biochem. 2002;311(2):119-126. (Pubitemid 35463470)
    • (2002) Analytical Biochemistry , vol.311 , Issue.2 , pp. 119-126
    • Lasne, F.1    Martin, L.2    Crepin, N.3    De Ceaurriz, J.4
  • 31
    • 0036840574 scopus 로고    scopus 로고
    • Comparison of the isoelectric focusing patterns of darbepoetin alfa, recombinant human erythropoietin, and endogenous erythropoietin from human urine
    • Catlin D.H., Breidbach A., Elliott S., Glaspy J. Comparison of the isoelectric focusing patterns of darbepoetin-alfa, recombinant human erythropoietin, and endogenous erythropoietin from human urine. Clin Chem. 2002;48(11):2057-2059. (Pubitemid 35222769)
    • (2002) Clinical Chemistry , vol.48 , Issue.11 , pp. 2057-2059
    • Catlin, D.H.1    Breidbach, A.2    Elliott, S.3    Glaspy, J.4
  • 35
    • 53449098195 scopus 로고    scopus 로고
    • Testing for recombinant human erythropoietin in urine: Problems associated with current anti doping testing
    • Lundby C., Achman-Andersen N.J., Thomsen J.J., Norgaard A.M., Robach P. Testing for recombinant human erythropoietin in urine: Problems associated with current anti doping testing. J Appl Physiol. 2008;105(2):417-419.
    • (2008) J Appl Physiol. , vol.105 , Issue.2 , pp. 417-419
    • Lundby, C.1    Achman-Andersen, N.J.2    Thomsen, J.J.3    Norgaard, A.M.4    Robach, P.5
  • 38
    • 74849126307 scopus 로고    scopus 로고
    • Proteolysis and autolysis of proteases and the detection of degradation products in doping control
    • Thomas A., Kohler M., Walpurgis K., Schänzer W., Thevis M. Proteolysis and autolysis of proteases and the detection of degradation products in doping control. Drug Test Anal. 2009;1(2):81-86.
    • (2009) Drug Test Anal. , vol.1 , Issue.2 , pp. 81-86
    • Thomas, A.1    Kohler, M.2    Walpurgis, K.3    Schänzer, W.4    Thevis, M.5
  • 39
    • 33845796987 scopus 로고    scopus 로고
    • Erythropoietin treatment elevates haemoglobin concentration by increasing red cell volume and depressing plasma volume
    • DOI 10.1113/jphysiol.2006.122689
    • Lundby C., Thomsen J.J., Boushel R., et al. Erythropoietin treatment elevates haemoglobin concentration by increasing red cell volume and depressing plasma volume. J Physiol. 2007;578(1):309-314. (Pubitemid 44971127)
    • (2007) Journal of Physiology , vol.578 , Issue.1 , pp. 309-314
    • Lundby, C.1    Thomsen, J.J.2    Boushel, R.3    Koskolou, M.4    Warberg, J.5    Calbet, J.A.L.6    Robach, P.7
  • 40
    • 33746945994 scopus 로고    scopus 로고
    • The effects of microdose recombinant human erythropoietin regimens in athletes
    • Ashenden M., Varlet-Marie E., Lasne F., Audran M. The effects of microdose recombinant human erythropoietin regimens in athletes. Haematologica. 2006;91(8):1143-1144. (Pubitemid 44204788)
    • (2006) Haematologica , vol.91 , Issue.8 , pp. 1143-1144
    • Ashenden, M.1    Varlet-Marie, E.2    Lasne, F.3    Audran, M.4
  • 41
    • 0037683360 scopus 로고    scopus 로고
    • Detection of recombinant human erythropoietin in urine by isoelectric focusing
    • DOI 10.1373/49.6.901
    • Breidbach A., Catlin D.H., Green G.A., Tregub I., Truong H., Gorzek J. Detection of recombinant human erythropoietin in urine by isoelectric focusing. Clin Chem. 2003;49(6):901-907. (Pubitemid 36623469)
    • (2003) Clinical Chemistry , vol.49 , Issue.6 , pp. 901-907
    • Breidbach, A.1    Catlin, D.H.2    Green, G.A.3    Tregub, I.4    Truong, H.5    Gorzek, J.6
  • 43
    • 33847685805 scopus 로고    scopus 로고
    • Detection window of Darbepoetin-alpha following one single subcutaneous injection
    • DOI 10.1016/j.cca.2007.01.014, PII S0009898107000174
    • Lamon S., Robinson N., Mangin P., Saugy M. Detection window of Darbepoetin-alpha following one single subcutaneous injection. Clin Chim Acta. 2007;379(1):145-149. (Pubitemid 46366986)
    • (2007) Clinica Chimica Acta , vol.379 , Issue.1-2 , pp. 145-149
    • Lamon, S.1    Robinson, N.2    Mangin, P.3    Saugy, M.4
  • 45
    • 33644875091 scopus 로고    scopus 로고
    • CERA (Continuous Erythropoietin Receptor Activator): A new erythropoiesis-stimulating agent for the treatment of anemia
    • Macdougall I.C. CERA (Continuous Erythropoietin Receptor Activator): A new erythropoiesis-stimulating agent for the treatment of anemia. Curr Hematol Rep. 2005;4(6):436-440.
    • (2005) Curr Hematol Rep. , vol.4 , Issue.6 , pp. 436-440
    • Macdougall, I.C.1
  • 50
    • 33748679131 scopus 로고    scopus 로고
    • Evaluation of the safety and pharmacodynamics of Hematide, a novel erythropoietic agent, in a phase 1, double-blind, placebo-controlled, dose-escalation study in healthy volunteers
    • DOI 10.1182/blood-2006-04-015818
    • Stead R.B., Lambert J., Wessels D., et al. Evaluation of the safety and pharmacodynamics of Hematide, a novel erythropoietic agent, in a phase 1, double-blind, placebo-controlled, doseescalation study in healthy volunteers. Blood. 2006;108(6):1830-1834. (Pubitemid 44394989)
    • (2006) Blood , vol.108 , Issue.6 , pp. 1830-1834
    • Stead, R.B.1    Lambert, J.2    Wessels, D.3    Iwashita, J.S.4    Leuther, K.K.5    Woodburn, K.W.6    Schatz, P.J.7    Okamoto, D.M.8    Naso, R.9    Duliege, A.-M.10
  • 51
    • 70350774297 scopus 로고    scopus 로고
    • A peptide-based erythropoietin-receptor agonist for pure red-cell aplasia
    • Macdougall I.C., Rossert J., Casadevall N., et al. A peptide-based erythropoietin-receptor agonist for pure red-cell aplasia. N Engl J Med. 2009;361(19):1848-1855.
    • (2009) N Engl J Med. , vol.361 , Issue.19 , pp. 1848-1855
    • Macdougall, I.C.1    Rossert, J.2    Casadevall, N.3
  • 52
    • 51849094530 scopus 로고    scopus 로고
    • A Phase I, single and fractionated, ascending-dose study evaluating the safety, pharmacokinetics, pharmacodynamics, and immunogenicity of an erythropoietin mimetic antibody fusion protein (CNTO 528) in healthy male subjects
    • Bouman-Thio E., Franson K., Miller B., et al. A Phase I, single and fractionated, ascending-dose study evaluating the safety, pharmacokinetics, pharmacodynamics, and immunogenicity of an erythropoietin mimetic antibody fusion protein (CNTO 528) in healthy male subjects. J Clin Pharmacol. 2008;48(10):1197-1207.
    • (2008) J Clin Pharmacol , vol.48 , Issue.10 , pp. 1197-1207
    • Bouman-Thio, E.1    Franson, K.2    Miller, B.3
  • 53
    • 66549127370 scopus 로고    scopus 로고
    • CNTO 530 functions as a potent EPO mimetic via unique sustained effects on bone marrow proerythroblast pools
    • Sathyanarayana P., Houde E., Marshall D., et al. CNTO 530 functions as a potent EPO mimetic via unique sustained effects on bone marrow proerythroblast pools. Blood. 2009;113(20):4955-4962.
    • (2009) Blood. , vol.113 , Issue.20 , pp. 4955-4962
    • Sathyanarayana, P.1    Houde, E.2    Marshall, D.3
  • 54
    • 77953854244 scopus 로고    scopus 로고
    • Hypoxic regulation of erythropoiesis and iron metabolism
    • Haase V.H. Hypoxic regulation of erythropoiesis and iron metabolism. Am J Physiol Renal Physiol. 2010;299(1):F1-F13.
    • (2010) Am J Physiol Renal Physiol. , vol.299 , Issue.1
    • Haase, V.H.1
  • 55
    • 34547493149 scopus 로고    scopus 로고
    • Hydroxylation of hypoxia-inducible transcription factors and chemical compounds targeting the HIF-alpha hydroxylases
    • DOI 10.2174/092986707781058850
    • Bruegge K., Jelkmann W., Metzen E. Hydroxylation of hypoxia-inducible transcription factors and chemical compounds targeting the HIF-alpha hydroxylases. Curr Med Chem. 2007;14(17):1853-1862. (Pubitemid 47163403)
    • (2007) Current Medicinal Chemistry , vol.14 , Issue.17 , pp. 1853-1862
    • Bruegge, K.1    Jelkmann, W.2    Metzen, E.3
  • 56
    • 0002226997 scopus 로고
    • Studies on erythropoiesis: V. The effect of cobalt on the production of erythropoietin
    • Goldwasser E., Jacobson L.O., Fried W., Plzak L.F. Studies on erythropoiesis: V. The effect of cobalt on the production of erythropoietin. Blood. 1958;13(1):55-60.
    • (1958) Blood. , vol.13 , Issue.1 , pp. 55-60
    • Goldwasser, E.1    Jacobson, L.O.2    Fried, W.3    Plzak, L.F.4
  • 57
    • 0037844847 scopus 로고    scopus 로고
    • Cobalt inhibits the interaction between hypoxia-inducible factor-alpha and von Hippel-Lindau protein by direct binding to hypoxia-inducible factor-alpha
    • DOI 10.1074/jbc.M300463200
    • Yuan Y., Hilliard G., Ferguson T., Millhorn D.E. Cobalt inhibits the interaction between hypoxiainducible factor-alpha and von Hippel-Lindau protein by direct binding to hypoxia-inducible factoralpha. J Biol Chem. 2003;278(18):15911-15916. (Pubitemid 36799707)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.18 , pp. 15911-15916
    • Yuan, Y.1    Hilliard, G.2    Ferguson, T.3    Millhorn, D.E.4
  • 58
    • 65249160538 scopus 로고    scopus 로고
    • Efficacy of recombinant erythropoietins: Is there unity of international units?
    • Jelkmann W. Efficacy of recombinant erythropoietins: Is there unity of international units? Nephrol Dial Transplant. 2009;24(5):1366-1368.
    • (2009) Nephrol Dial Transplant. , vol.24 , Issue.5 , pp. 1366-1368
    • Jelkmann, W.1
  • 59
    • 2342506640 scopus 로고
    • The use of cobaltous chloride in the anemia associated with chronic renal disease
    • Gardner F.H. The use of cobaltous chloride in the anemia associated with chronic renal disease. J Lab Clin Med. 1953;41(1):56-64.
    • (1953) J Lab Clin Med. , vol.41 , Issue.1 , pp. 56-64
    • Gardner, F.H.1
  • 60
    • 84907106072 scopus 로고
    • Cobalt: A review
    • Taylor A., Marks V. Cobalt: A review. J Hum Nutr. 1978;32(3):165-177.
    • (1978) J Hum Nutr. , vol.32 , Issue.3 , pp. 165-177
    • Taylor, A.1    Marks, V.2
  • 61
    • 0017279692 scopus 로고
    • Possible cobalt toxicity in maintenance hemodialysis patients after treatment with cobaltous chloride: A study of blood and tissue cobalt concentrations in normal subjects and patients with terminal and renal failure
    • Curtis J.R., Goode G.C., Herrington J., Urdaneta L.E. Possible cobalt toxicity in maintenance hemodialysis patients after treatment with cobaltous chloride: A study of blood and tissue cobalt concentrations in normal subjects and patients with terminal and renal failure. Clin Nephrol. 1976;5(2):61-65.
    • (1976) Clin Nephrol. , vol.5 , Issue.2 , pp. 61-65
    • Curtis, J.R.1    Goode, G.C.2    Herrington, J.3    Urdaneta, L.E.4
  • 62
    • 34248223079 scopus 로고    scopus 로고
    • Blood doping by cobalt: Should we measure cobalt in athletes?
    • Lippi G., Franchini M., Guidi G.C. Blood doping by cobalt: Should we measure cobalt in athletes? J Occup Med Toxicol. 2006;1:18.
    • (2006) J Occup Med Toxicol. , vol.1 , pp. 18
    • Lippi, G.1    Franchini, M.2    Guidi, G.C.3
  • 65
    • 59349098621 scopus 로고    scopus 로고
    • Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease
    • Fraisl P., Aragones J., Carmeliet P. Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease. Nat Rev Drug Discov. 2009;8(2):139-152.
    • (2009) Nat Rev Drug Discov. , vol.8 , Issue.2 , pp. 139-152
    • Fraisl, P.1    Aragones, J.2    Carmeliet, P.3
  • 67
    • 78649876180 scopus 로고    scopus 로고
    • Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD
    • Bernhardt W.M., Wiesener M.S., Scigalla P., et al. Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD. J Am Soc Nephrol. 2010;21(12):2151-2156.
    • (2010) J Am Soc Nephrol. , vol.21 , Issue.12 , pp. 2151-2156
    • Bernhardt, W.M.1    Wiesener, M.S.2    Scigalla, P.3
  • 68
    • 0141483465 scopus 로고    scopus 로고
    • A GATAspecific inhibitor (K-7174) rescues anemia induced by IL-1beta, TNF-alpha, or L-NMMA
    • Imagawa S., Nakano Y., Obara N., et al. A GATAspecific inhibitor (K-7174) rescues anemia induced by IL-1beta, TNF-alpha, or L-NMMA. FASEB J. 2003;17(12):1742-1744.
    • (2003) FASEB J. , vol.17 , Issue.12 , pp. 1742-1744
    • Imagawa, S.1    Nakano, Y.2    Obara, N.3
  • 69
    • 10244260353 scopus 로고    scopus 로고
    • Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease
    • DOI 10.1182/blood-2004-04-1631
    • Nakano Y., Imagawa S., Matsumoto K., et al. Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease. Blood. 2004;104(13):4300-4307. (Pubitemid 39620186)
    • (2004) Blood , vol.104 , Issue.13 , pp. 4300-4307
    • Nakano, Y.1    Imagawa, S.2    Matsumoto, K.3    Stockmann, C.4    Obara, N.5    Suzuki, N.6    Doi, T.7    Kodama, T.8    Takahashi, S.9    Nagasawa, T.10    Yamamoto, M.11
  • 71
    • 0036785428 scopus 로고    scopus 로고
    • Long-term reversal of chronic anemia using a hypoxiaregulated erythropoietin gene therapy
    • Binley K., Askham Z., Iqball S., et al. Long-term reversal of chronic anemia using a hypoxiaregulated erythropoietin gene therapy. Blood. 2002;100(7):2406-2413.
    • (2002) Blood. , vol.100 , Issue.7 , pp. 2406-2413
    • Binley, K.1    Askham, Z.2    Iqball, S.3
  • 72
    • 4444305201 scopus 로고    scopus 로고
    • "Genetic doping" with erythropoietin cDNA in primate muscle is detectable
    • DOI 10.1016/j.ymthe.2004.07.024, PII S1525001604013589
    • Lasne F., Martin L., De Ceaurriz J., Larcher T., Moullier P., Chenuaud P. "Genetic doping" with erythropoietin cDNA in primate muscle is detectable. Mol Ther. 2004;10(3):409-410. (Pubitemid 39186104)
    • (2004) Molecular Therapy , vol.10 , Issue.3 , pp. 409-410
    • Lasne, F.1    Martin, L.2    De Ceaurriz, J.3    Larcher, T.4    Moullier, P.5    Chenuaud, P.6
  • 75
    • 13544262341 scopus 로고    scopus 로고
    • Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer
    • DOI 10.1182/blood-2004-06-2501
    • Rivera V.M., Gao G.P., Grant R.L., et al. Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer. Blood. 2005;105(4):1424-1430. (Pubitemid 40223657)
    • (2005) Blood , vol.105 , Issue.4 , pp. 1424-1430
    • Rivera, V.M.1    Gao, G.-P.2    Grant, R.L.3    Schnell, M.A.4    Zoltick, P.W.5    Rozamus, L.W.6    Clackson, T.7    Wilson, J.M.8
  • 76
    • 62849115532 scopus 로고    scopus 로고
    • Establishing a novel single-copy primer-internal intron-spanning PCR (spiPCR) procedure for the direct detection of gene doping
    • Beiter T., Zimmermann M., Fragasso A., et al. Establishing a novel single-copy primer-internal intron-spanning PCR (spiPCR) procedure for the direct detection of gene doping. Exerc Immunol Rev. 2008;14:73-85.
    • (2008) Exerc Immunol Rev. , vol.14 , pp. 73-85
    • Beiter, T.1    Zimmermann, M.2    Fragasso, A.3
  • 77
    • 79952484973 scopus 로고    scopus 로고
    • Direct and long-term detection of gene doping in conventional blood samples
    • Beiter T., Zimmermann M., Fragasso A., et al. Direct and long-term detection of gene doping in conventional blood samples. Gene Ther. 2011;18(3):225-231.
    • (2011) Gene Ther. , vol.18 , Issue.3 , pp. 225-231
    • Beiter, T.1    Zimmermann, M.2    Fragasso, A.3
  • 78
    • 77955664126 scopus 로고    scopus 로고
    • Gene doping detection: Evaluation of approach for direct detection of gene transfer using erythropoietin as a model system
    • Baoutina A., Coldham T., Bains G.S., Emslie K.R. Gene doping detection: Evaluation of approach for direct detection of gene transfer using erythropoietin as a model system. Gene Ther. 2010;17(8):1022-1032.
    • (2010) Gene Ther. , vol.17 , Issue.8 , pp. 1022-1032
    • Baoutina, A.1    Coldham, T.2    Bains, G.S.3    Emslie, K.R.4
  • 80
    • 0031957179 scopus 로고    scopus 로고
    • Stimulation of erythropoietin secretion by continuous subcutaneous infusion of recombinant human GH in anemic patients with chronic renal failure
    • DOI 10.1530/eje.0.1380302
    • Sohmiya M., Ishikawa K., Kato Y. Stimulation of erythropoietin secretion by continuous subcutaneous infusion of recombinant human GH in anemic patients with chronic renal failure. Eur J Endocrinol. 1998;138(3):302-306. (Pubitemid 28154780)
    • (1998) European Journal of Endocrinology , vol.138 , Issue.3 , pp. 302-306
    • Sohmiya, M.1    Ishikawa, K.2    Kato, Y.3
  • 81
    • 0020393390 scopus 로고
    • A new candidate for the regulation of erythropoiesis. Insulin-like growth factor I
    • DOI 10.1016/0014-5793(82)81081-8
    • Kurtz A., Jelkmann W., Bauer C. A new candidate for the regulation of erythropoiesis: Insulin-like growth factor I. FEBS Lett. 1982;149(1):105-108. (Pubitemid 13177107)
    • (1982) FEBS Letters , vol.149 , Issue.1 , pp. 105-108
    • Kurtz, A.1    Jelkmann, W.2    Bauer, C.3
  • 84
    • 59149103502 scopus 로고    scopus 로고
    • A retrospective cohort study of blood hemoglobin levels in blood donors and competitive rowers
    • Johansson P.I., Ullum H., Jensen K., Secher N.H. A retrospective cohort study of blood hemoglobin levels in blood donors and competitive rowers. Scand J Med Sci Sports. 2009;19(1):92-95.
    • (2009) Scand J Med Sci Sports. , vol.19 , Issue.1 , pp. 92-95
    • Johansson, P.I.1    Ullum, H.2    Jensen, K.3    Secher, N.H.4
  • 85
    • 33344455954 scopus 로고    scopus 로고
    • The definition of anemia: What is the lower limit of normal of the blood hemoglobin concentration?
    • DOI 10.1182/blood-2005-07-3046
    • Beutler E., Waalen J. The definition of anemia: What is the lower limit of normal of the blood hemoglobin concentration? Blood. 2006;107(5):1747-1750. (Pubitemid 43289347)
    • (2006) Blood , vol.107 , Issue.5 , pp. 1747-1750
    • Beutler, E.1    Waalen, J.2
  • 87
    • 0038100454 scopus 로고    scopus 로고
    • Hematologic passport for athletes competing in endurance sports: A feasibility study
    • Malcovati L., Pascutto C., Cazzola M. Hematologic passport for athletes competing in endurance sports: A feasibility study. Haematologica. 2003;88(5):570-581. (Pubitemid 36648447)
    • (2003) Haematologica , vol.88 , Issue.5 , pp. 570-581
    • Malcovati, L.1    Pascutto, C.2    Cazzola, M.3
  • 88
    • 35748935881 scopus 로고    scopus 로고
    • Bayesian detection of abnormal hematological values to introduce a no-start rule for heterogeneous populations of athletes
    • DOI 10.3324/haematol.11182
    • Robinson N., Sottas P.E., Mangin P., Saugy M. Bayesian detection of abnormal hematological values to introduce a no-start rule for heterogeneous populations of athletes. Haematologica. 2007;92(8):1143-1144. (Pubitemid 350144226)
    • (2007) Haematologica , vol.92 , Issue.8 , pp. 1143-1144
    • Robinson, N.1    Sottas, P.-E.2    Mangin, P.3    Saugy, M.4
  • 89
    • 0033774328 scopus 로고    scopus 로고
    • Reticulocyte parameters as potential discriminators of recombinant human erythropoietin abuse in elite athletes
    • Parisotto R., Gore C.J., Hahn A.G., et al. Reticulocyte parameters as potential discriminators of recombinant human erythropoietin abuse in elite athletes. Int J Sports Med. 2000;21(7):471-479.
    • (2000) Int J Sports Med. , vol.21 , Issue.7 , pp. 471-479
    • Parisotto, R.1    Gore, C.J.2    Hahn, A.G.3
  • 93
    • 33645392494 scopus 로고    scopus 로고
    • A third generation approach to detect erythropoietin abuse in athletes
    • Sharpe K., Ashenden M.J., Schumacher Y.O. A third generation approach to detect erythropoietin abuse in athletes. Haematologica. 2006;91(3):356-363.
    • (2006) Haematologica. , vol.91 , Issue.3 , pp. 356-363
    • Sharpe, K.1    Ashenden, M.J.2    Schumacher, Y.O.3
  • 94
    • 61749104555 scopus 로고    scopus 로고
    • A forensic approach to the interpretation of blood doping markers
    • Sottas P.E., Robinson N., Saugy M., Niggli O. A forensic approach to the interpretation of blood doping markers. Law Probability Risk. 2008;7(3):191-210.
    • (2008) Law Probability Risk. , vol.7 , Issue.3 , pp. 191-210
    • Sottas, P.E.1    Robinson, N.2    Saugy, M.3    Niggli, O.4
  • 95
    • 33645862262 scopus 로고    scopus 로고
    • Statistical classification of abnormal blood profiles in athletes
    • Article 3
    • Sottas PE. Statistical classification of abnormal blood profiles in athletes. Int J Biostatistics. 2006;2(1):Article 3.
    • (2006) Int J Biostatistics , vol.2 , Issue.1
    • Sottas, P.E.1
  • 96
    • 80052413470 scopus 로고    scopus 로고
    • Distinction between endogenous and exogenous erythropoietin: Marker methods
    • Ghigo E, ed. New York, NY: Springer
    • Segura J., Zorzoli M. Distinction between endogenous and exogenous erythropoietin: Marker methods. In: Ghigo E, ed. Hormone Use and Abuse by Athletes. New York, NY: Springer; 2011:151-161.
    • (2011) Hormone Use and Abuse by Athletes , pp. 151-161
    • Segura, J.1    Zorzoli, M.2
  • 97
    • 0034254356 scopus 로고    scopus 로고
    • Erythropoietin, iron, and erythropoiesis
    • Goodnough L.T., Skikne B., Brugnara C. Erythropoietin, iron, and erythropoiesis. Blood. 2000;96(3):823-833. (Pubitemid 30616842)
    • (2000) Blood , vol.96 , Issue.3 , pp. 823-833
    • Goodnough, L.T.1    Skikne, B.2    Brugnara, C.3
  • 98
    • 33745782713 scopus 로고    scopus 로고
    • Effects of blood withdrawal and reinfusion on biomarkers of erythropoiesis in humans: Implications for anti-doping strategies
    • Damsgaard R., Munch T., Mørkeberg J., Mortensen S.P., Gonzalez-Alonso J. Effects of blood withdrawal and reinfusion on biomarkers of erythropoiesis in humans: Implications for anti-doping strategies. Haematologica. 2006;91(7):1006-1008. (Pubitemid 44023168)
    • (2006) Haematologica , vol.91 , Issue.7 , pp. 1006-1008
    • Damsgaard, R.1    Munch, T.2    Morkeberg, J.3    Mortensen, S.P.4    Gonzalez-Alonso, J.5
  • 101
    • 79957778888 scopus 로고    scopus 로고
    • Detection of autologous blood doping with adaptively evaluated biomarkers of doping: A longitudinal blinded study
    • published online ahead of print March 7, 2011 doi: 10.1111/j.1537-2995. 2011.03076.x
    • Pottgiesser T., Sottas P.E., Echteler T., Robinson N., Umhau M., Schumacher Y.O. Detection of autologous blood doping with adaptively evaluated biomarkers of doping: A longitudinal blinded study [published online ahead of print March 7, 2011]. Transfusion. doi: 10.1111/j.1537-2995.2011.03076.x.
    • Transfusion
    • Pottgiesser, T.1    Sottas, P.E.2    Echteler, T.3    Robinson, N.4    Umhau, M.5    Schumacher, Y.O.6
  • 102
    • 79952599004 scopus 로고    scopus 로고
    • Detecting autologous blood transfusions: A comparison of three passport approaches and four blood markers
    • Mørkeberg J., Sharpe K., Belhage B., et al. Detecting autologous blood transfusions: A comparison of three passport approaches and four blood markers. Scand J Med Sci Sports. 2011;21(2):235-243.
    • (2011) Scand J Med Sci Sports. , vol.21 , Issue.2 , pp. 235-243
    • Mørkeberg, J.1    Sharpe, K.2    Belhage, B.3
  • 103
    • 66849083462 scopus 로고    scopus 로고
    • Screening for autologous blood transfusions
    • Mørkeberg J., Belhage B., Ashenden M., et al. Screening for autologous blood transfusions. Int J Sports Med. 2009;30(4):285-292.
    • (2009) Int J Sports Med. , vol.30 , Issue.4 , pp. 285-292
    • Mørkeberg, J.1    Belhage, B.2    Ashenden, M.3
  • 104
    • 33646712786 scopus 로고    scopus 로고
    • Reticulocyte count, mean reticulocyte volume, immature reticulocyte fraction, and mean sphered cell volume in elite athletes: Reference values and comparison with the general population
    • DOI 10.1515/CCLM.2006.094
    • Banfi G., Mauri C., Morelli B., Di Gaetano N., Malgeri U., Melegati G. Reticulocyte count, mean reticulocyte volume, immature reticulocyte fraction, and mean sphered cell volume in elite athletes: Reference values and comparison with the general population. Clin Chem Lab Med. 2006;44(5):616-622. (Pubitemid 43735636)
    • (2006) Clinical Chemistry and Laboratory Medicine , vol.44 , Issue.5 , pp. 616-622
    • Banfi, G.1    Mauri, C.2    Morelli, B.3    Di, G.N.4    Malgeri, U.5    Melegati, G.6
  • 105
    • 0141538185 scopus 로고    scopus 로고
    • The effect of common hematologic abnormalities on the ability of blood models to detect erythropoietin abuse by athletes
    • Parisotto R., Ashenden M.J., Gore C.J., Sharpe K., Hopkins W., Hahn A.G. The effect of common hematologic abnormalities on the ability of blood models to detect erythropoietin abuse by athletes. Haematologica. 2003;88(8):931-940. (Pubitemid 37128094)
    • (2003) Haematologica , vol.88 , Issue.8 , pp. 931-940
    • Parisotto, R.1    Ashenden, M.J.2    Gore, C.J.3    Sharpe, K.4    Hopkins, W.5    Hahn, A.G.6
  • 106
    • 0028438939 scopus 로고
    • Effects of subcutaneous recombinant human erythropoietin in normal subjects: Development of decreased reticulocyte hemoglobin content and iron-deficient erythropoiesis
    • Brugnara C., Colella G.M., Cremins J., et al. Effects of subcutaneous recombinant human erythropoietin in normal subjects: Development of decreased reticulocyte hemoglobin content and iron-deficient erythropoiesis. J Lab Clin Med. 1994;123(5):660-667.
    • (1994) J Lab Clin Med. , vol.123 , Issue.5 , pp. 660-667
    • Brugnara, C.1    Colella, G.M.2    Cremins, J.3
  • 107
    • 0034071563 scopus 로고    scopus 로고
    • 'Blood doping' with recombinant erythropoietin (rhEPO) and assessment of functional iron deficiency in healthy volunteers [1]
    • DOI 10.1046/j.1365-2141.2000.01902.x
    • Breymann C., Rohling R., Krafft A., Huch A., Huch R. 'Blood doping' with recombinant erythropoietin (rhEPO) and assessment of functional iron deficiency in healthy volunteers. Br J Haematol. 2000;108(4):883-884. (Pubitemid 30304528)
    • (2000) British Journal of Haematology , vol.108 , Issue.4 , pp. 883-884
    • Breymann, C.1    Rohling, R.2    Krafft, A.3    Huch, A.4    Huch, R.5
  • 110
    • 34249659363 scopus 로고    scopus 로고
    • Behaviour of reticulocyte counts and immature reticulocyte fraction during a competitive season in élite athletes of four different sports
    • DOI 10.1111/j.1751-553X.2006.00847.x
    • Banfi G., Del Fabbro M. Behaviour of reticulocyte counts and immature reticulocyte fraction during a competitive season in elite athletes of four different sports. Int J Lab Hematol. 2007;29(2):127-131. (Pubitemid 46911164)
    • (2007) International Journal of Laboratory Hematology , vol.29 , Issue.2 , pp. 127-131
    • Banfi, G.1    Del, F.M.2
  • 112
    • 33947188218 scopus 로고    scopus 로고
    • An assessment of recombinant human erythropoietin effect on reticulocyte production rate and lifespan distribution in healthy subjects
    • DOI 10.1007/s11095-006-9195-y
    • Krzyzanski W., Perez-Ruixo J.J. An assessment of recombinant human erythropoietin effect on reticulocyte production rate and lifespan distribution in healthy subjects. Pharm Res. 2007;24(4):758-772. (Pubitemid 46411964)
    • (2007) Pharmaceutical Research , vol.24 , Issue.4 , pp. 758-772
    • Krzyzanski, W.1    Perez-Ruixo, J.J.2
  • 113
    • 0036512898 scopus 로고    scopus 로고
    • Effects of prolonged low doses of recombinant human erythropoietin during submaximal and maximal exercise
    • DOI 10.1007/s00421-001-0560-6
    • Russell G., Gore C.J., Ashenden M.J., Parisotto R., Hahn A.G. Effects of prolonged low doses of recombinant human erythropoietin during submaximal and maximal exercise. Eur J Appl Physiol. 2002;86(5):442-449. (Pubitemid 41399062)
    • (2002) European Journal of Applied Physiology , vol.86 , Issue.5 , pp. 442-449
    • Russell, G.1    Gore, C.J.2    Ashenden, M.J.3    Parisotto, R.4    Hahn, A.G.5
  • 116
    • 0030071458 scopus 로고    scopus 로고
    • Optimal timing of repeated rh-erythropoietin administration improves its effectiveness in stimulating erythropoiesis in healthy volunteers
    • Breymann C., Bauer C., Major A., et al. Optimal timing of repeated rh-erythropoietin administration improves its effectiveness in stimulating erythropoiesis in healthy volunteers. Br J Haematol. 1996;92(2):295-301. (Pubitemid 26042922)
    • (1996) British Journal of Haematology , vol.92 , Issue.2 , pp. 295-301
    • Breymann, C.1    Bauer, C.2    Major, A.3    Zimmermann, R.4    Gautschi, K.5    Huch, A.6    Huch, R.7
  • 117
    • 0141478876 scopus 로고    scopus 로고
    • Effect of altitude on second-generation blood tests to detect erythropoietin abuse by athletes
    • Ashenden M.J., Gore C.J., Parisotto R., Sharpe K., Hopkins W.G., Hahn A.G. Effect of altitude on second-generation blood tests to detect erythropoietin abuse by athletes. Haematologica. 2003;88(9):1053-1062. (Pubitemid 37151157)
    • (2003) Haematologica , vol.88 , Issue.9 , pp. 1053-1062
    • Ashenden, M.J.1    Gore, C.J.2    Parisotto, R.3    Sharpe, K.4    Hopkins, W.G.5    Hahn, A.G.6
  • 118
    • 34547515012 scopus 로고    scopus 로고
    • Intermittent hypoxia exposure in a hypobaric chamber and erythropoietin abuse interpretation
    • DOI 10.1080/02640410601001640, PII 780725780
    • Abellan R., Ventura R., Remacha A.F., Rodriguez F.A., Pascual J.A., Segura J. Intermittent hypoxia exposure in a hypobaric chamber and erythropoietin abuse interpretation. J Sports Sci. 2007;25(11):1241-1250. (Pubitemid 47180518)
    • (2007) Journal of Sports Sciences , vol.25 , Issue.11 , pp. 1241-1250
    • Abellan, R.1    Ventura, R.2    Remacha, A.F.3    Rodriguez, F.A.4    Pascual, J.A.5    Segura, J.6
  • 119
    • 75649152273 scopus 로고    scopus 로고
    • CAS doping jurisprudence: What can we learn?
    • McLaren HR. CAS doping jurisprudence: what can we learn? Int Sports Law Rev. 2006;Issue 1:4-22.
    • (2006) Int Sports Law Rev , Issue.1 , pp. 4-22
    • McLaren, H.R.1
  • 120
    • 77954864895 scopus 로고    scopus 로고
    • Screening for recombinant human erythropoietin using [Hb], reticulocytes, the off(hr score), off (z score) and Hb (z score): Status of the Blood Passport
    • Bornø A., Aachmann-Andersen N.J., Munch-Andersen T., Hulston C.J., Lundby C. Screening for recombinant human erythropoietin using [Hb], reticulocytes, the OFF(hr score), OFF (z score) and Hb (z score): Status of the Blood Passport. Eur J Appl Physiol. 2010;109(3):537-543.
    • (2010) Eur J Appl Physiol. , vol.109 , Issue.3 , pp. 537-543
    • Bornø, A.1    Aachmann-Andersen, N.J.2    Munch-Andersen, T.3    Hulston, C.J.4    Lundby, C.5
  • 121
    • 69449102898 scopus 로고    scopus 로고
    • Anti-doping researchers should conform to certain statistical standards from forensic science
    • Faber K., Sjerps M. Anti-doping researchers should conform to certain statistical standards from forensic science. Sci Justice. 2009;49(3):214-215.
    • (2009) Sci Justice. , vol.49 , Issue.3 , pp. 214-215
    • Faber, K.1    Sjerps, M.2
  • 122
    • 51649131144 scopus 로고    scopus 로고
    • Doping: A paradigm shift has taken place in testing
    • Sottas P.E., Saudan C., Saugy M. Doping: A paradigm shift has taken place in testing. Nature. 2008;455(720):166.
    • (2008) Nature. , vol.455 , Issue.720 , pp. 166
    • Sottas, P.E.1    Saudan, C.2    Saugy, M.3
  • 123
    • 34247141049 scopus 로고    scopus 로고
    • Current anti-doping policy: A critical appraisal
    • Kayser B., Mauron A., Miah A. Current anti-doping policy: A critical appraisal. BMC Med Ethics. 2007;8:2.
    • (2007) BMC Med Ethics. , vol.8 , pp. 2
    • Kayser, B.1    Mauron, A.2    Miah, A.3
  • 124
    • 77952529086 scopus 로고    scopus 로고
    • The effects of growth hormone on body composition and physical performance in recreational athletes: A randomized trial
    • Meinhardt U., Nelson A.E., Hansen J.L., et al. The effects of growth hormone on body composition and physical performance in recreational athletes: A randomized trial. Ann Intern Med. 2010;152(9):568-577.
    • (2010) Ann Intern Med. , vol.152 , Issue.9 , pp. 568-577
    • Meinhardt, U.1    Nelson, A.E.2    Hansen, J.L.3
  • 125
    • 65649123829 scopus 로고    scopus 로고
    • Erythropoiesis stimulating agents and techniques: A challenge for doping analysts
    • Jelkmann W. Erythropoiesis stimulating agents and techniques: A challenge for doping analysts. Curr Med Chem. 2009;16(10):1236-1247.
    • (2009) Curr Med Chem. , vol.16 , Issue.10 , pp. 1236-1247
    • Jelkmann, W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.