Delivery of an erythropoietin-Fc fusion protein by inhalation in humans through an immunoglobulin transport pathway

Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung

Volumn 18, Issue 3, 2005, Pages 294-303

  Dumont, Jennifer A ^a   Bitonti, Alan J ^a   Clark, Darren ^b   Evans, Sean ^c   Pickford, Matthew ^b   Newman, Stephen P ^b  

^a Syntonix Pharmaceuticals Inc   (United States)

^b PHARMACEUTICAL PROFILES LTD   (United Kingdom)

^c Critical Therapeutics Inc   (United States)

Author keywords

Erythropoietin; FcRn; Lung; Pulmonary delivery

Indexed keywords

ERYTHROPOIETIN FC FUSION PROTEIN; FC RECEPTOR; HYBRID PROTEIN; IMMUNOGLOBULIN; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; UNCLASSIFIED DRUG;

ADULT; AEROSOL; AGED; AIRWAY; ANIMAL CELL; AREA UNDER THE CURVE; ARTICLE; CELL TRANSPORT; CLINICAL TRIAL; CONCENTRATION RESPONSE; DISTRIBUTION VOLUME; DOSE RESPONSE; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG HALF LIFE; EPITHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN EXPERIMENT; MALE; NONHUMAN; NORMAL HUMAN; PHASE 1 CLINICAL TRIAL; PRIMATE; RETICULOCYTE; SAFETY;

ADMINISTRATION, INHALATION; ADOLESCENT; ADULT; AEROSOLS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; ERYTHROPOIETIN; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; LUNG; MALE; MIDDLE AGED; NEBULIZERS AND VAPORIZERS; RADIOPHARMACEUTICALS; RECEPTORS, FC; RECOMBINANT FUSION PROTEINS; RETICULOCYTES; TECHNETIUM TC 99M PENTETATE; VITAL CAPACITY;

EID: 25844528107     PISSN: 08942684     EISSN: None     Source Type: Journal    
DOI: 10.1089/jam.2005.18.294     Document Type: Article

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