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Volumn 6, Issue 9, 2011, Pages

Studies of metabolic phenotypic correlates of 15 obesity associated gene variants

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARTICLE; BAT2 GENE; BDNF GENE; BODY MASS; CONTROLLED STUDY; ETV5 GENE; FAIM2 GENE; GENE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; GNPDA2 GENE; HUMAN; KCTD15 GENE; MAF GENE; MAJOR CLINICAL STUDY; METABOLISM; MORBID OBESITY; MTCH2 GENE; NEGR1 GENE; NON INSULIN DEPENDENT DIABETES MELLITUS; NPC1 GENE; OBESITY; PTER GENE; RISK ASSESSMENT; RISK FACTOR; SEC16B GENE; SH2B1 GENE; TMEM18 GENE; ANTHROPOMETRY; GENE FREQUENCY; GENE LOCUS; GENETICS; MIDDLE AGED; PHENOTYPE; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 80052397686     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023531     Document Type: Article
Times cited : (57)

References (44)
  • 1
    • 0024948256 scopus 로고
    • Genetic and environmental influences on obesity assessed by the adoption method
    • Sorensen TI, (1989) Genetic and environmental influences on obesity assessed by the adoption method. Rev Epidemiol Sante Publique 37: 525-531.
    • (1989) Rev Epidemiol Sante Publique , vol.37 , pp. 525-531
    • Sorensen, T.I.1
  • 3
    • 0030843960 scopus 로고    scopus 로고
    • Genetic and environmental factors in relative body weight and human adiposity
    • Maes HH, Neale MC, Eaves LJ, (1997) Genetic and environmental factors in relative body weight and human adiposity. Behav Genet 27: 325-351.
    • (1997) Behav Genet , vol.27 , pp. 325-351
    • Maes, H.H.1    Neale, M.C.2    Eaves, L.J.3
  • 4
    • 33645825830 scopus 로고    scopus 로고
    • A common genetic variant is associated with adult and childhood obesity
    • Herbert A, Gerry NP, McQueen MB, Heid IM, Pfeufer A, et al. (2006) A common genetic variant is associated with adult and childhood obesity. Science 312: 279-283.
    • (2006) Science , vol.312 , pp. 279-283
    • Herbert, A.1    Gerry, N.P.2    McQueen, M.B.3    Heid, I.M.4    Pfeufer, A.5
  • 5
    • 34248594090 scopus 로고    scopus 로고
    • A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
    • Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM, et al. (2007) A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 316: 889-894.
    • (2007) Science , vol.316 , pp. 889-894
    • Frayling, T.M.1    Timpson, N.J.2    Weedon, M.N.3    Zeggini, E.4    Freathy, R.M.5
  • 6
    • 34547625955 scopus 로고    scopus 로고
    • Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
    • Scuteri A, Sanna S, Chen WM, Uda M, Albai G, et al. (2007) Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet 3: e115.
    • (2007) PLoS Genet , vol.3
    • Scuteri, A.1    Sanna, S.2    Chen, W.M.3    Uda, M.4    Albai, G.5
  • 7
    • 44849086097 scopus 로고    scopus 로고
    • Genome-wide association scans identified CTNNBL1 as a novel gene for obesity
    • Liu YJ, Liu XG, Wang L, Dina C, Yan H, et al. (2008) Genome-wide association scans identified CTNNBL1 as a novel gene for obesity. Hum Mol Genet 17: 1803-1813.
    • (2008) Hum Mol Genet , vol.17 , pp. 1803-1813
    • Liu, Y.J.1    Liu, X.G.2    Wang, L.3    Dina, C.4    Yan, H.5
  • 8
    • 41749090524 scopus 로고    scopus 로고
    • Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants
    • Hinney A, Nguyen TT, Scherag A, Friedel S, Brönner G, et al. (2007) Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants. PLoS One 2: e1361.
    • (2007) PLoS One , vol.2
    • Hinney, A.1    Nguyen, T.T.2    Scherag, A.3    Friedel, S.4    Brönner, G.5
  • 9
    • 38449098674 scopus 로고    scopus 로고
    • Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation
    • Andreasen CH, Stender-Petersen KL, Mogensen MS, Torekov SS, Wegner L, et al. (2008) Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation. Diabetes 57: 95-101.
    • (2008) Diabetes , vol.57 , pp. 95-101
    • Andreasen, C.H.1    Stender-Petersen, K.L.2    Mogensen, M.S.3    Torekov, S.S.4    Wegner, L.5
  • 10
    • 40749094439 scopus 로고    scopus 로고
    • Variants in the FTO gene are associated with common obesity in the Belgian population
    • Peeters A, Beckers S, Verrijken A, Roevens P, Peeters P, et al. (2008) Variants in the FTO gene are associated with common obesity in the Belgian population. Mol Genet Metab 93: 481-484.
    • (2008) Mol Genet Metab , vol.93 , pp. 481-484
    • Peeters, A.1    Beckers, S.2    Verrijken, A.3    Roevens, P.4    Peeters, P.5
  • 11
    • 58149528039 scopus 로고    scopus 로고
    • Replication of the association of common rs9939609 variant of FTO with increased BMI in an Australian adult twin population but no evidence for gene by environment (G×E) interaction
    • Cornes BK, Lind PA, Medland SE, Montgomery GW, Nyholt DR, et al. (2009) Replication of the association of common rs9939609 variant of FTO with increased BMI in an Australian adult twin population but no evidence for gene by environment (G×E) interaction. Int J Obes 33: 75-79.
    • (2009) Int J Obes , vol.33 , pp. 75-79
    • Cornes, B.K.1    Lind, P.A.2    Medland, S.E.3    Montgomery, G.W.4    Nyholt, D.R.5
  • 12
    • 44349166252 scopus 로고    scopus 로고
    • Common genetic variation near MC4R is associated with waist circumference and insulin resistance
    • Chambers JC, Elliott P, Zabaneh D, Zhang W, Li Y, et al. (2008) Common genetic variation near MC4R is associated with waist circumference and insulin resistance. Nat Genet 40: 716-718.
    • (2008) Nat Genet , vol.40 , pp. 716-718
    • Chambers, J.C.1    Elliott, P.2    Zabaneh, D.3    Zhang, W.4    Li, Y.5
  • 13
    • 44349142294 scopus 로고    scopus 로고
    • Common variants near MC4R are associated with fat mass, weight and risk of obesity
    • Loos RJ, Lindgren CM, Li S, Wheeler E, Zhao JH, et al. (2008) Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 40: 768-775.
    • (2008) Nat Genet , vol.40 , pp. 768-775
    • Loos, R.J.1    Lindgren, C.M.2    Li, S.3    Wheeler, E.4    Zhao, J.H.5
  • 14
    • 62749100569 scopus 로고    scopus 로고
    • Variants near MC4R are associated with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes
    • Zobel DP, Andreasen CH, Grarup N, Eiberg H, Sørensen TI, et al. (2009) Variants near MC4R are associated with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes. Diabetes 58: 757-764.
    • (2009) Diabetes , vol.58 , pp. 757-764
    • Zobel, D.P.1    Andreasen, C.H.2    Grarup, N.3    Eiberg, H.4    Sørensen, T.I.5
  • 15
    • 74249117319 scopus 로고    scopus 로고
    • Common variants near MC4R in relation to body fat, body fat distribution, metabolic traits and energy expenditure
    • Kring SI, Holst C, Toubro S, Astrup A, Hansen T, et al. (2010) Common variants near MC4R in relation to body fat, body fat distribution, metabolic traits and energy expenditure. Int J Obes 34: 182-189.
    • (2010) Int J Obes , vol.34 , pp. 182-189
    • Kring, S.I.1    Holst, C.2    Toubro, S.3    Astrup, A.4    Hansen, T.5
  • 16
    • 48349113289 scopus 로고    scopus 로고
    • Common nonsynonymous variants in PCSK1 confer risk of obesity
    • Benzinou M, Creemers JW, Choquet H, Lobbens S, Dina C, et al. (2008) Common nonsynonymous variants in PCSK1 confer risk of obesity. Nat Genet 40: 943-945.
    • (2008) Nat Genet , vol.40 , pp. 943-945
    • Benzinou, M.1    Creemers, J.W.2    Choquet, H.3    Lobbens, S.4    Dina, C.5
  • 17
    • 77954277206 scopus 로고    scopus 로고
    • Combined analyses of 20 common obesity susceptibility variants
    • Sandholt CH, Sparso T, Grarup N, Albrechtsen A, Almind K, et al. (2010) Combined analyses of 20 common obesity susceptibility variants. Diabetes 59: 1667-1673.
    • (2010) Diabetes , vol.59 , pp. 1667-1673
    • Sandholt, C.H.1    Sparso, T.2    Grarup, N.3    Albrechtsen, A.4    Almind, K.5
  • 18
    • 69449093447 scopus 로고    scopus 로고
    • Association of variants in the PCSK1 gene with obesity in the EPIC-Norfolk study
    • Kilpelainen TO, Bingham SA, Khaw KT, Wareham NJ, Loos RJ, (2009) Association of variants in the PCSK1 gene with obesity in the EPIC-Norfolk study. Hum Mol Genet 18: 3496-3501.
    • (2009) Hum Mol Genet , vol.18 , pp. 3496-3501
    • Kilpelainen, T.O.1    Bingham, S.A.2    Khaw, K.T.3    Wareham, N.J.4    Loos, R.J.5
  • 19
    • 58149163141 scopus 로고    scopus 로고
    • Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
    • 2009
    • Thorleifsson G, Walters GB, Gudbjartsson DF, Steinthorsdottir V, Sulem P, et al. (2009) Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet 41: 18-24, 2009.
    • (2009) Nat Genet , vol.41 , pp. 18-24
    • Thorleifsson, G.1    Walters, G.B.2    Gudbjartsson, D.F.3    Steinthorsdottir, V.4    Sulem, P.5
  • 20
    • 58149163142 scopus 로고    scopus 로고
    • Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
    • Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, et al. (2009) Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 41: 25-34.
    • (2009) Nat Genet , vol.41 , pp. 25-34
    • Willer, C.J.1    Speliotes, E.K.2    Loos, R.J.3    Li, S.4    Lindgren, C.M.5
  • 21
    • 59149097625 scopus 로고    scopus 로고
    • Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations
    • Meyre D, Delplanque J, Chevre JC, Lecoeur C, Lobbens C, et al. (2009) Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat Genet 41: 157-159.
    • (2009) Nat Genet , vol.41 , pp. 157-159
    • Meyre, D.1    Delplanque, J.2    Chevre, J.C.3    Lecoeur, C.4    Lobbens, C.5
  • 22
    • 59149105634 scopus 로고    scopus 로고
    • A supersized list of obesity genes
    • Hofker M, Wijmenga C, (2009) A supersized list of obesity genes. Nat Genet 41: 139-140.
    • (2009) Nat Genet , vol.41 , pp. 139-140
    • Hofker, M.1    Wijmenga, C.2
  • 23
    • 77952288486 scopus 로고    scopus 로고
    • The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children
    • Almen MS, Jacobsson JA, Shaik JH, Olszewski PK, Cedernaes J, et al. (2010) The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children. BMC Med Genet 11: 58.
    • (2010) BMC Med Genet , vol.11 , pp. 58
    • Almen, M.S.1    Jacobsson, J.A.2    Shaik, J.H.3    Olszewski, P.K.4    Cedernaes, J.5
  • 24
    • 77952956214 scopus 로고    scopus 로고
    • Novel Obesity Risk Loci Do Not Determine Distribution of Body Fat Depots: A Whole-body MRI/MRS study
    • Haupt A, Thamer C, Heni M, Machicao F, Machann J, et al. (2009) Novel Obesity Risk Loci Do Not Determine Distribution of Body Fat Depots: A Whole-body MRI/MRS study. Obesity 18: 1212-1217.
    • (2009) Obesity , vol.18 , pp. 1212-1217
    • Haupt, A.1    Thamer, C.2    Heni, M.3    Machicao, F.4    Machann, J.5
  • 25
    • 73649136827 scopus 로고    scopus 로고
    • Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population
    • Hotta K, Nakamura M, Nakamura T, Matsuo T, Nakata Y, et al. (2009) Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population. J Hum Genet 54: 727-731.
    • (2009) J Hum Genet , vol.54 , pp. 727-731
    • Hotta, K.1    Nakamura, M.2    Nakamura, T.3    Matsuo, T.4    Nakata, Y.5
  • 26
    • 77957912843 scopus 로고    scopus 로고
    • Genes and lifestyle factors in obesity: results from 12 462 subjects from MONICA/KORA
    • Holzapfel C, Grallert H, Huth C, Wahl S, Fischer B, et al. (2010) Genes and lifestyle factors in obesity: results from 12 462 subjects from MONICA/KORA. Int J Obes 18: 1538-1545.
    • (2010) Int J Obes , vol.18 , pp. 1538-1545
    • Holzapfel, C.1    Grallert, H.2    Huth, C.3    Wahl, S.4    Fischer, B.5
  • 27
    • 77952405825 scopus 로고    scopus 로고
    • Two New Loci for Body-Weight Regulation Identified in a Joint Analysis of Genome-Wide Association Studies for early-Onset Extreme Obesity in French and German Study Groups
    • Scherag A, Dina C, Hinney A, Vatin V, Scherag S, et al. (2010) Two New Loci for Body-Weight Regulation Identified in a Joint Analysis of Genome-Wide Association Studies for early-Onset Extreme Obesity in French and German Study Groups. PLoS Gen 4: e1000916.
    • (2010) PLoS Gen , vol.4
    • Scherag, A.1    Dina, C.2    Hinney, A.3    Vatin, V.4    Scherag, S.5
  • 28
    • 64549158008 scopus 로고    scopus 로고
    • Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden
    • Renstrom F, Payne F, Nordstrom A, Brito EC, Rolandsson O, et al. (2009) Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden. Hum Mol Genet 18: 1489-1496.
    • (2009) Hum Mol Genet , vol.18 , pp. 1489-1496
    • Renstrom, F.1    Payne, F.2    Nordstrom, A.3    Brito, E.C.4    Rolandsson, O.5
  • 29
    • 70349783304 scopus 로고    scopus 로고
    • Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference
    • Bauer F, Elbers CC, Adan RA, Loos RJ, Onland-Moret NC, et al. (2009) Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference. Am J Clin Nutr 90: 951-959.
    • (2009) Am J Clin Nutr , vol.90 , pp. 951-959
    • Bauer, F.1    Elbers, C.C.2    Adan, R.A.3    Loos, R.J.4    Onland-Moret, N.C.5
  • 30
    • 77952746932 scopus 로고    scopus 로고
    • Implication of Genetic Variants Near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with Obesity and Type 2 Diabetes in 7705 Chinese
    • Ng MC, Tam CH, So WY, Ho JS, Chan AW, et al. (2010) Implication of Genetic Variants Near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with Obesity and Type 2 Diabetes in 7705 Chinese. J Clin Endocrinol Metab 95: 2418-2425.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 2418-2425
    • Ng, M.C.1    Tam, C.H.2    So, W.Y.3    Ho, J.S.4    Chan, A.W.5
  • 31
    • 33845663497 scopus 로고    scopus 로고
    • SH2B1 (SH2-B) and JAK2: a multifunctional adaptor protein and kinase made for each other
    • Maures TJ, Kurzer JH, Carter-Su C, (2007) SH2B1 (SH2-B) and JAK2: a multifunctional adaptor protein and kinase made for each other. Trends Endocrinol Metab 18: 38-45.
    • (2007) Trends Endocrinol Metab , vol.18 , pp. 38-45
    • Maures, T.J.1    Kurzer, J.H.2    Carter-Su, C.3
  • 32
    • 4344581405 scopus 로고    scopus 로고
    • Disruption of the SH2-B gene causes age-dependent insulin resistance and glucose intolerance
    • Duan C, Yang H, White MF, Rui L, (2004) Disruption of the SH2-B gene causes age-dependent insulin resistance and glucose intolerance. Mol Cell Biol 24: 7435-7443.
    • (2004) Mol Cell Biol , vol.24 , pp. 7435-7443
    • Duan, C.1    Yang, H.2    White, M.F.3    Rui, L.4
  • 33
    • 33645891474 scopus 로고    scopus 로고
    • Differential role of SH2-B and APS in regulating energy and glucose homeostasis
    • Li M, Ren D, Iseki M, Takaki S, Rui L, (2006) Differential role of SH2-B and APS in regulating energy and glucose homeostasis. Endocrinology 147: 2163-2170.
    • (2006) Endocrinology , vol.147 , pp. 2163-2170
    • Li, M.1    Ren, D.2    Iseki, M.3    Takaki, S.4    Rui, L.5
  • 34
    • 33846822094 scopus 로고    scopus 로고
    • Neuronal SH2B1 is essential for controlling energy and glucose homeostasis
    • Ren D, Zhou Y, Morris D, Li M, Li Z, et al. (2007) Neuronal SH2B1 is essential for controlling energy and glucose homeostasis. J Clin Invest 117: 397-406.
    • (2007) J Clin Invest , vol.117 , pp. 397-406
    • Ren, D.1    Zhou, Y.2    Morris, D.3    Li, M.4    Li, Z.5
  • 35
    • 70349086181 scopus 로고    scopus 로고
    • SH2B1 enhances insulin sensitivity by both stimulating the insulin receptor and inhibiting tyrosine dephosphorylation of insulin receptor substrate proteins
    • Morris DL, Cho KW, Zhou Y, Rui L, (2009) SH2B1 enhances insulin sensitivity by both stimulating the insulin receptor and inhibiting tyrosine dephosphorylation of insulin receptor substrate proteins. Diabetes 58: 2039-2047.
    • (2009) Diabetes , vol.58 , pp. 2039-2047
    • Morris, D.L.1    Cho, K.W.2    Zhou, Y.3    Rui, L.4
  • 36
    • 0038392755 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor
    • Xu B, Goulding EH, Zang K, Cepoi D, Cone RD, et al. (2003) Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor. Nat Neurosci 6: 736-742.
    • (2003) Nat Neurosci , vol.6 , pp. 736-742
    • Xu, B.1    Goulding, E.H.2    Zang, K.3    Cepoi, D.4    Cone, R.D.5
  • 37
    • 18144435678 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor regulates glucose metabolism by modulating energy balance in diabetic mice
    • Nakagawa T, Tsuchida A, Itakura Y, Nonomura T, Ono M, et al. (2000) Brain-derived neurotrophic factor regulates glucose metabolism by modulating energy balance in diabetic mice. Diabetes 49: 436-444.
    • (2000) Diabetes , vol.49 , pp. 436-444
    • Nakagawa, T.1    Tsuchida, A.2    Itakura, Y.3    Nonomura, T.4    Ono, M.5
  • 38
    • 0031577526 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor reduces blood glucose level in obese diabetic mice but not in normal mice
    • Ono M, Ichihara J, Nonomura T, Itakura Y, Taiji M, et al. (1997) Brain-derived neurotrophic factor reduces blood glucose level in obese diabetic mice but not in normal mice. Biochem Biophys Res Commun 238: 633-637.
    • (1997) Biochem Biophys Res Commun , vol.238 , pp. 633-637
    • Ono, M.1    Ichihara, J.2    Nonomura, T.3    Itakura, Y.4    Taiji, M.5
  • 40
    • 20144370557 scopus 로고    scopus 로고
    • Human brain derived neurotrophic factor (BDNF) genes, splicing patterns, and assessments of associations with substance abuse and Parkinson's Disease
    • Liu QR, Walther D, Drgon T, Polesskaya O, Lesnick TG, et al. (2005) Human brain derived neurotrophic factor (BDNF) genes, splicing patterns, and assessments of associations with substance abuse and Parkinson's Disease. Am J Med Genet B Neuropsychiatr Genet 134B: 93-103.
    • (2005) Am J Med Genet B Neuropsychiatr Genet , vol.134 B , pp. 93-103
    • Liu, Q.R.1    Walther, D.2    Drgon, T.3    Polesskaya, O.4    Lesnick, T.G.5
  • 41
    • 34547499702 scopus 로고    scopus 로고
    • Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters
    • Pruunsild P, Kazantseva A, Aid T, Palm K, Timmusk T, (2007) Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters. Genomics 90: 397-406.
    • (2007) Genomics , vol.90 , pp. 397-406
    • Pruunsild, P.1    Kazantseva, A.2    Aid, T.3    Palm, K.4    Timmusk, T.5
  • 42
    • 78049337953 scopus 로고    scopus 로고
    • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
    • Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, et al. (2010) Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat genet 42: 937-948.
    • (2010) Nat Genet , vol.42 , pp. 937-948
    • Speliotes, E.K.1    Willer, C.J.2    Berndt, S.I.3    Monda, K.L.4    Thorleifsson, G.5
  • 43
    • 0346394178 scopus 로고    scopus 로고
    • A randomized non-pharmacological intervention study for prevention of ischaemic heart disease: baseline results Inter99
    • Jorgensen T, Borch-Johnsen K, Thomsen TF, Ibsen H, Glumer C, et al. (2003) A randomized non-pharmacological intervention study for prevention of ischaemic heart disease: baseline results Inter99. Eur J Cardiovasc Prev Rehabil 10: 377-386.
    • (2003) Eur J Cardiovasc Prev Rehabil , vol.10 , pp. 377-386
    • Jorgensen, T.1    Borch-Johnsen, K.2    Thomsen, T.F.3    Ibsen, H.4    Glumer, C.5
  • 44
    • 0033808127 scopus 로고    scopus 로고
    • The ADDITION study: proposed trial of the cost-effectiveness of an intensive multifactorial intervention on morbidity and mortality among people with Type 2 diabetes detected by screening
    • Lauritzen T, Griffin S, Borch-Johnsen K, Wareham NJ, Wolffenbuttel BH, et al. (2000) The ADDITION study: proposed trial of the cost-effectiveness of an intensive multifactorial intervention on morbidity and mortality among people with Type 2 diabetes detected by screening. Int J Obes Relat Metab Disord 24 (Suppl 3): S6-11.
    • (2000) Int J Obes Relat Metab Disord , vol.24 , Issue.SUPPL. 3
    • Lauritzen, T.1    Griffin, S.2    Borch-Johnsen, K.3    Wareham, N.J.4    Wolffenbuttel, B.H.5


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