The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children

BMC Medical Genetics

Volumn 11, Issue 1, 2010, Pages

  Almén, Markus S ^a   Jacobsson, Josefin A ^a   Shaik, Jafar H A ^a   Olszewski, Pawel K ^a,b   Cedernaes, Jonathan ^a   Alsiö, Johan ^a   Sreedharan, Smitha ^a   Levine, Allen S ^b,c   Fredriksson, Robert ^a   Marcus, Claude ^d   Schiöth, Helgi B ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b University of Minnesota   (United States)

^c Department of Food Science and Nutrition ^*  (United States)

^d KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN PROTEIN; MEMBRANE PROTEIN; PROTEIN TMEM18; UNCLASSIFIED DRUG; TMEM18 PROTEIN, HUMAN;

ADOLESCENT; ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BRAIN NERVE CELL; BRAIN REGION; BRAIN STEM; CHILD; CONTROLLED STUDY; FEMALE; GENE EXPRESSION PROFILING; GENE LOCATION; GENE LOCUS; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENOTYPE; HUMAN; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; OBESITY; PHYLOGENY; PRESCHOOL CHILD; RAT; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; AMINO ACID SEQUENCE; ANIMAL; ANIMAL MODEL; BODY MASS; BRAIN; C57BL MOUSE; CLASSIFICATION; CYTOLOGY; GENETICS; METABOLISM; MOLECULAR GENETICS; NERVE CELL; TISSUE DISTRIBUTION;

RATTUS;

ADOLESCENT; AMINO ACID SEQUENCE; ANIMALS; BODY MASS INDEX; BODY WEIGHT; BRAIN; CHILD; FEMALE; GENE EXPRESSION PROFILING; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MODELS, ANIMAL; MOLECULAR SEQUENCE DATA; NEURONS; OBESITY; PHYLOGENY; POLYMORPHISM, SINGLE NUCLEOTIDE; RATS; SEQUENCE ALIGNMENT; TISSUE DISTRIBUTION; YOUNG ADULT;

EID: 77952288486     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-11-58     Document Type: Article

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