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Volumn 40, Issue 3, 2011, Pages 485-507

Hormonal Mechanisms Underlying the Relationship Between Obesity and Breast Cancer

Author keywords

Adipokines; Breast cancer; Estrogen receptor; IGFs; Obesity

Indexed keywords

ACETYLSALICYLIC ACID; ADIPOCYTOKINE; ADIPONECTIN; ANASTROZOLE; ANTIESTROGEN; ANTINEOPLASTIC AGENT; AROMATASE INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; GHRELIN; GLUCOCORTICOID; INSULIN; INTERLEUKIN 6; LEPTIN; LETROZOLE; METFORMIN; NONSTEROID ANTIINFLAMMATORY AGENT; OBESTATIN; PEGYLATED LEPTIN PEPTIDE RECEPTOR ANTAGONIST; SCATTER FACTOR; SOMATOMEDIN; SOMATOMEDIN B; SOMATOMEDIN C; TAMOXIFEN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 80052192474     PISSN: 08898529     EISSN: 15584410     Source Type: Journal    
DOI: 10.1016/j.ecl.2011.05.010     Document Type: Review
Times cited : (41)

References (201)
  • 1
    • 41149161956 scopus 로고    scopus 로고
    • Obesity among adults in the United States-no statistically significant chance since 2003-2004
    • Ogden C.L., Carroll M.D., McDowell M.A., et al. Obesity among adults in the United States-no statistically significant chance since 2003-2004. NCHS Data Brief 2007, (1):1-8.
    • (2007) NCHS Data Brief , Issue.1 , pp. 1-8
    • Ogden, C.L.1    Carroll, M.D.2    McDowell, M.A.3
  • 2
    • 28444462917 scopus 로고    scopus 로고
    • Epidemiologic aspects of overweight and obesity in the United States
    • Flegal K.M. Epidemiologic aspects of overweight and obesity in the United States. Physiol Behav 2005, 86(5):599-602.
    • (2005) Physiol Behav , vol.86 , Issue.5 , pp. 599-602
    • Flegal, K.M.1
  • 3
    • 70349207410 scopus 로고    scopus 로고
    • Annual medical spending attributable to obesity: payer-and service-specific estimates
    • Finkelstein E.A., Trogdon J.G., Cohen J.W., et al. Annual medical spending attributable to obesity: payer-and service-specific estimates. Health Aff (Millwood) 2009, 28(5):w822-w831.
    • (2009) Health Aff (Millwood) , vol.28 , Issue.5
    • Finkelstein, E.A.1    Trogdon, J.G.2    Cohen, J.W.3
  • 4
    • 16144365807 scopus 로고    scopus 로고
    • Birthweight as a risk factor for breast cancer
    • Michels K.B., Trichopoulos D., Robins J.M., et al. Birthweight as a risk factor for breast cancer. Lancet 1996, 348(9041):1542-1546.
    • (1996) Lancet , vol.348 , Issue.9041 , pp. 1542-1546
    • Michels, K.B.1    Trichopoulos, D.2    Robins, J.M.3
  • 5
    • 4143133439 scopus 로고    scopus 로고
    • Is the association of birth weight with premenopausal breast cancer risk mediated through childhood growth?
    • dos Santos Silva I., De Stavola B.L., Hardy R.J., et al. Is the association of birth weight with premenopausal breast cancer risk mediated through childhood growth?. Br J Cancer 2004, 91(3):519-524.
    • (2004) Br J Cancer , vol.91 , Issue.3 , pp. 519-524
    • dos Santos Silva, I.1    De Stavola, B.L.2    Hardy, R.J.3
  • 6
    • 0035805050 scopus 로고    scopus 로고
    • Cancer risk in Swedish women: the relation to size at birth
    • Andersson S.W., Bengtsson C., Hallberg L., et al. Cancer risk in Swedish women: the relation to size at birth. Br J Cancer 2001, 84(9):1193-1198.
    • (2001) Br J Cancer , vol.84 , Issue.9 , pp. 1193-1198
    • Andersson, S.W.1    Bengtsson, C.2    Hallberg, L.3
  • 7
    • 0035863371 scopus 로고    scopus 로고
    • Birth characteristics and breast cancer risk: a study among like-sexed twins
    • Hubinette A., Lichtenstein P., Ekbom A., et al. Birth characteristics and breast cancer risk: a study among like-sexed twins. Int J Cancer 2001, 91(2):248-251.
    • (2001) Int J Cancer , vol.91 , Issue.2 , pp. 248-251
    • Hubinette, A.1    Lichtenstein, P.2    Ekbom, A.3
  • 8
    • 35948970288 scopus 로고    scopus 로고
    • Body shape throughout life and correlations with IGFs and GH
    • Schernhammer E.S., Tworoger S.S., Eliassen A.H., et al. Body shape throughout life and correlations with IGFs and GH. Endocr Relat Cancer 2007, 14(3):721-732.
    • (2007) Endocr Relat Cancer , vol.14 , Issue.3 , pp. 721-732
    • Schernhammer, E.S.1    Tworoger, S.S.2    Eliassen, A.H.3
  • 9
    • 0038021568 scopus 로고    scopus 로고
    • The relationship among circulating insulin-like growth factor (IGF)-I, IGF-binding proteins-1 and -2, and birth anthropometry: a prospective study
    • Boyne M.S., Thame M., Bennett F.I., et al. The relationship among circulating insulin-like growth factor (IGF)-I, IGF-binding proteins-1 and -2, and birth anthropometry: a prospective study. J Clin Endocrinol Metab 2003, 88(4):1687-1691.
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.4 , pp. 1687-1691
    • Boyne, M.S.1    Thame, M.2    Bennett, F.I.3
  • 10
    • 18244373744 scopus 로고    scopus 로고
    • Birth weight as a predictor of breast cancer: a case-control study in Norway
    • Vatten L.J., Maehle B.O., Lund Nilsen T.I., et al. Birth weight as a predictor of breast cancer: a case-control study in Norway. Br J Cancer 2002, 86(1):89-91.
    • (2002) Br J Cancer , vol.86 , Issue.1 , pp. 89-91
    • Vatten, L.J.1    Maehle, B.O.2    Lund Nilsen, T.I.3
  • 11
    • 39449084929 scopus 로고    scopus 로고
    • Relative weight at age 12 and risk of postmenopausal breast cancer
    • Bardia A., Vachon C.M., Olson J.E., et al. Relative weight at age 12 and risk of postmenopausal breast cancer. Cancer Epidemiol Biomarkers Prev 2008, 17(2):374-378.
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , Issue.2 , pp. 374-378
    • Bardia, A.1    Vachon, C.M.2    Olson, J.E.3
  • 12
    • 33751517687 scopus 로고    scopus 로고
    • Longitudinal study on the role of body size in premenopausal breast cancer
    • Michels K.B., Terry K.L., Willett W.C. Longitudinal study on the role of body size in premenopausal breast cancer. Arch Intern Med 2006, 166(21):2395-2402.
    • (2006) Arch Intern Med , vol.166 , Issue.21 , pp. 2395-2402
    • Michels, K.B.1    Terry, K.L.2    Willett, W.C.3
  • 13
    • 77952942744 scopus 로고    scopus 로고
    • Body fatness at young ages and risk of breast cancer throughout life
    • Baer H.J., Tworoger S.S., Hankinson S.E., et al. Body fatness at young ages and risk of breast cancer throughout life. Am J Epidemiol 2010, 171(11):1183-1194.
    • (2010) Am J Epidemiol , vol.171 , Issue.11 , pp. 1183-1194
    • Baer, H.J.1    Tworoger, S.S.2    Hankinson, S.E.3
  • 14
    • 0034666098 scopus 로고    scopus 로고
    • Pooled analysis of prospective cohort studies on height, weight, and breast cancer risk
    • van den Brandt P.A., Spiegelman D., Yaun S.S., et al. Pooled analysis of prospective cohort studies on height, weight, and breast cancer risk. Am J Epidemiol 2000, 152(6):514-527.
    • (2000) Am J Epidemiol , vol.152 , Issue.6 , pp. 514-527
    • van den Brandt, P.A.1    Spiegelman, D.2    Yaun, S.S.3
  • 15
    • 37049013701 scopus 로고    scopus 로고
    • Cancer incidence and mortality in relation to body mass index in the Million Women Study: cohort study
    • Reeves G.K., Pirie K., Beral V., et al. Cancer incidence and mortality in relation to body mass index in the Million Women Study: cohort study. BMJ 2007, 335(7630):1134.
    • (2007) BMJ , vol.335 , Issue.7630 , pp. 1134
    • Reeves, G.K.1    Pirie, K.2    Beral, V.3
  • 16
    • 49149112491 scopus 로고    scopus 로고
    • Risk factors for the incidence of breast cancer: do they affect survival from the disease?
    • Barnett G.C., Shah M., Redman K., et al. Risk factors for the incidence of breast cancer: do they affect survival from the disease?. J Clin Oncol 2008, 26(20):3310-3316.
    • (2008) J Clin Oncol , vol.26 , Issue.20 , pp. 3310-3316
    • Barnett, G.C.1    Shah, M.2    Redman, K.3
  • 17
    • 51649125007 scopus 로고    scopus 로고
    • Effect of obesity and other lifestyle factors on mortality in women with breast cancer
    • Dal Maso L., Zucchetto A., Talamini R., et al. Effect of obesity and other lifestyle factors on mortality in women with breast cancer. Int J Cancer 2008, 123(9):2188-2194.
    • (2008) Int J Cancer , vol.123 , Issue.9 , pp. 2188-2194
    • Dal Maso, L.1    Zucchetto, A.2    Talamini, R.3
  • 18
    • 0037464510 scopus 로고    scopus 로고
    • Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults
    • Calle E.E., Rodriguez C., Walker-Thurmond K., et al. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med 2003, 348(17):1625-1638.
    • (2003) N Engl J Med , vol.348 , Issue.17 , pp. 1625-1638
    • Calle, E.E.1    Rodriguez, C.2    Walker-Thurmond, K.3
  • 19
    • 70849089229 scopus 로고    scopus 로고
    • Epidemiology of breast cancer subtypes in two prospective cohort studies of breast cancer survivors
    • Kwan M.L., Kushi L.H., Weltzien E., et al. Epidemiology of breast cancer subtypes in two prospective cohort studies of breast cancer survivors. Breast Cancer Res 2009, 11(3):R31.
    • (2009) Breast Cancer Res , vol.11 , Issue.3
    • Kwan, M.L.1    Kushi, L.H.2    Weltzien, E.3
  • 20
    • 3442878171 scopus 로고    scopus 로고
    • Body mass index as a prognostic feature in operable breast cancer: the International Breast Cancer Study Group experience
    • Berclaz G., Li S., Price K.N., et al. Body mass index as a prognostic feature in operable breast cancer: the International Breast Cancer Study Group experience. Ann Oncol 2004, 15(6):875-884.
    • (2004) Ann Oncol , vol.15 , Issue.6 , pp. 875-884
    • Berclaz, G.1    Li, S.2    Price, K.N.3
  • 21
    • 33745298444 scopus 로고    scopus 로고
    • Adult weight gain and histopathologic characteristics of breast cancer among postmenopausal women
    • Feigelson H.S., Patel A.V., Teras L.R., et al. Adult weight gain and histopathologic characteristics of breast cancer among postmenopausal women. Cancer 2006, 107(1):12-21.
    • (2006) Cancer , vol.107 , Issue.1 , pp. 12-21
    • Feigelson, H.S.1    Patel, A.V.2    Teras, L.R.3
  • 22
    • 0038545570 scopus 로고    scopus 로고
    • Effect of family history, obesity and exercise on breast cancer risk among postmenopausal women
    • Carpenter C.L., Ross R.K., Paganini-Hill A., et al. Effect of family history, obesity and exercise on breast cancer risk among postmenopausal women. Int J Cancer 2003, 106(1):96-102.
    • (2003) Int J Cancer , vol.106 , Issue.1 , pp. 96-102
    • Carpenter, C.L.1    Ross, R.K.2    Paganini-Hill, A.3
  • 23
    • 33746928252 scopus 로고    scopus 로고
    • Diet, lifestyle and BRCA-related breast cancer risk among French-Canadians
    • Nkondjock A., Robidoux A., Paredes Y., et al. Diet, lifestyle and BRCA-related breast cancer risk among French-Canadians. Breast Cancer Res Treat 2006, 98(3):285-294.
    • (2006) Breast Cancer Res Treat , vol.98 , Issue.3 , pp. 285-294
    • Nkondjock, A.1    Robidoux, A.2    Paredes, Y.3
  • 24
    • 35748969106 scopus 로고    scopus 로고
    • Childhood diet and insulin-like growth factors in adulthood: 65-year follow-up of the Boyd Orr Cohort
    • Martin R.M., Holly J.M., Middleton N., et al. Childhood diet and insulin-like growth factors in adulthood: 65-year follow-up of the Boyd Orr Cohort. Eur J Clin Nutr 2007, 61(11):1281-1292.
    • (2007) Eur J Clin Nutr , vol.61 , Issue.11 , pp. 1281-1292
    • Martin, R.M.1    Holly, J.M.2    Middleton, N.3
  • 25
    • 33748751005 scopus 로고    scopus 로고
    • Associations of adiposity from childhood into adulthood with insulin resistance and the insulin-like growth factor system: 65-year follow-up of the Boyd Orr Cohort
    • Martin R.M., Holly J.M., Davey Smith G., et al. Associations of adiposity from childhood into adulthood with insulin resistance and the insulin-like growth factor system: 65-year follow-up of the Boyd Orr Cohort. J Clin Endocrinol Metab 2006, 91(9):3287-3295.
    • (2006) J Clin Endocrinol Metab , vol.91 , Issue.9 , pp. 3287-3295
    • Martin, R.M.1    Holly, J.M.2    Davey Smith, G.3
  • 26
    • 0012473279 scopus 로고
    • The nuclear receptor superfamily: the second decade
    • Mangelsdorf D.J., Thummel C., Beato M., et al. The nuclear receptor superfamily: the second decade. Cell 1995, 83(6):835-839.
    • (1995) Cell , vol.83 , Issue.6 , pp. 835-839
    • Mangelsdorf, D.J.1    Thummel, C.2    Beato, M.3
  • 27
    • 0034783960 scopus 로고    scopus 로고
    • Mechanisms of estrogen action
    • Nilsson S., Makela S., Treuter E., et al. Mechanisms of estrogen action. Physiol Rev 2001, 81(4):1535-1565.
    • (2001) Physiol Rev , vol.81 , Issue.4 , pp. 1535-1565
    • Nilsson, S.1    Makela, S.2    Treuter, E.3
  • 28
    • 46749108373 scopus 로고    scopus 로고
    • ERbeta in breast cancer-onlooker, passive player, or active protector?
    • Fox E.M., Davis R.J., Shupnik M.A. ERbeta in breast cancer-onlooker, passive player, or active protector?. Steroids 2008, 73(11):1039-1051.
    • (2008) Steroids , vol.73 , Issue.11 , pp. 1039-1051
    • Fox, E.M.1    Davis, R.J.2    Shupnik, M.A.3
  • 29
    • 0035496450 scopus 로고    scopus 로고
    • The role of estrogen receptors in breast cancer metastasis
    • Fuqua S.A. The role of estrogen receptors in breast cancer metastasis. J Mammary Gland Biol Neoplasia 2001, 6(4):407-417.
    • (2001) J Mammary Gland Biol Neoplasia , vol.6 , Issue.4 , pp. 407-417
    • Fuqua, S.A.1
  • 30
    • 67349223542 scopus 로고    scopus 로고
    • Estrogen receptor beta in breast cancer-diagnostic and therapeutic implications
    • Hartman J., Strom A., Gustafsson J.A. Estrogen receptor beta in breast cancer-diagnostic and therapeutic implications. Steroids 2009, 74(8):635-641.
    • (2009) Steroids , vol.74 , Issue.8 , pp. 635-641
    • Hartman, J.1    Strom, A.2    Gustafsson, J.A.3
  • 31
    • 0023210536 scopus 로고
    • Adipose tissue as a source of hormones
    • Siiteri P.K. Adipose tissue as a source of hormones. Am J Clin Nutr 1987, 45(Suppl 1):277-282.
    • (1987) Am J Clin Nutr , vol.45 , Issue.SUPPL. 1 , pp. 277-282
    • Siiteri, P.K.1
  • 32
    • 33745713939 scopus 로고    scopus 로고
    • Aromatase and the breast: regulation and clinical aspects
    • Miller W.R. Aromatase and the breast: regulation and clinical aspects. Maturitas 2006, 54(4):335-341.
    • (2006) Maturitas , vol.54 , Issue.4 , pp. 335-341
    • Miller, W.R.1
  • 33
    • 70249096223 scopus 로고    scopus 로고
    • Tissue estradiol is selectively elevated in receptor positive breast cancers while tumour estrone is reduced independent of receptor status
    • Lonning P.E., Helle H., Duong N.K., et al. Tissue estradiol is selectively elevated in receptor positive breast cancers while tumour estrone is reduced independent of receptor status. J Steroid Biochem Mol Biol 2009, 117(1-3):31-41.
    • (2009) J Steroid Biochem Mol Biol , vol.117 , Issue.1-3 , pp. 31-41
    • Lonning, P.E.1    Helle, H.2    Duong, N.K.3
  • 34
    • 66949133235 scopus 로고    scopus 로고
    • Aromatase expression is increased in BRCA1 mutation carriers
    • Chand A.L., Simpson E.R., Clyne C.D. Aromatase expression is increased in BRCA1 mutation carriers. BMC Cancer 2009, 9:148.
    • (2009) BMC Cancer , vol.9 , pp. 148
    • Chand, A.L.1    Simpson, E.R.2    Clyne, C.D.3
  • 35
    • 0031848636 scopus 로고    scopus 로고
    • Functional role of estrogen metabolism in target cells: review and perspectives
    • Zhu B.T., Conney A.H. Functional role of estrogen metabolism in target cells: review and perspectives. Carcinogenesis 1998, 19(1):1-27.
    • (1998) Carcinogenesis , vol.19 , Issue.1 , pp. 1-27
    • Zhu, B.T.1    Conney, A.H.2
  • 36
    • 0024466246 scopus 로고
    • Relationship between the pubertal fall in sex hormone binding globulin and insulin-like growth factor binding protein-I. A synchronized approach to pubertal development?
    • Holly J.M., Smith C.P., Dunger D.B., et al. Relationship between the pubertal fall in sex hormone binding globulin and insulin-like growth factor binding protein-I. A synchronized approach to pubertal development?. Clin Endocrinol (Oxf) 1989, 31(3):277-284.
    • (1989) Clin Endocrinol (Oxf) , vol.31 , Issue.3 , pp. 277-284
    • Holly, J.M.1    Smith, C.P.2    Dunger, D.B.3
  • 37
    • 0025039746 scopus 로고
    • Decreased sex hormone binding globulin (SHBG) and insulin-like growth factor binding protein (IGFBP-1) in extreme obesity
    • Weaver J.U., Holly J.M., Kopelman P.G., et al. Decreased sex hormone binding globulin (SHBG) and insulin-like growth factor binding protein (IGFBP-1) in extreme obesity. Clin Endocrinol (Oxf) 1990, 33(3):415-422.
    • (1990) Clin Endocrinol (Oxf) , vol.33 , Issue.3 , pp. 415-422
    • Weaver, J.U.1    Holly, J.M.2    Kopelman, P.G.3
  • 38
    • 33846837398 scopus 로고    scopus 로고
    • Relation of BMI and physical activity to sex hormones in postmenopausal women
    • McTiernan A., Wu L., Chen C., et al. Relation of BMI and physical activity to sex hormones in postmenopausal women. Obesity (Silver Spring) 2006, 14(9):1662-1677.
    • (2006) Obesity (Silver Spring) , vol.14 , Issue.9 , pp. 1662-1677
    • McTiernan, A.1    Wu, L.2    Chen, C.3
  • 39
    • 30944469849 scopus 로고    scopus 로고
    • Estrogen carcinogenesis in breast cancer
    • Yager J.D., Davidson N.E. Estrogen carcinogenesis in breast cancer. N Engl J Med 2006, 354(3):270-282.
    • (2006) N Engl J Med , vol.354 , Issue.3 , pp. 270-282
    • Yager, J.D.1    Davidson, N.E.2
  • 40
    • 34547741589 scopus 로고    scopus 로고
    • Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression
    • Vona-Davis L., Rose D.P. Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression. Endocr Relat Cancer 2007, 14(2):189-206.
    • (2007) Endocr Relat Cancer , vol.14 , Issue.2 , pp. 189-206
    • Vona-Davis, L.1    Rose, D.P.2
  • 41
    • 0037123341 scopus 로고    scopus 로고
    • Endogenous sex hormones and breast cancer in postmenopausal women: reanalysis of nine prospective studies
    • Key T., Appleby P., Barnes I., et al. Endogenous sex hormones and breast cancer in postmenopausal women: reanalysis of nine prospective studies. J Natl Cancer Inst 2002, 94(8):606-616.
    • (2002) J Natl Cancer Inst , vol.94 , Issue.8 , pp. 606-616
    • Key, T.1    Appleby, P.2    Barnes, I.3
  • 42
    • 0032475436 scopus 로고    scopus 로고
    • Plasma sex steroid hormone levels and risk of breast cancer in postmenopausal women
    • Hankinson S.E., Willett W.C., Manson J.E., et al. Plasma sex steroid hormone levels and risk of breast cancer in postmenopausal women. J Natl Cancer Inst 1998, 90(17):1292-1299.
    • (1998) J Natl Cancer Inst , vol.90 , Issue.17 , pp. 1292-1299
    • Hankinson, S.E.1    Willett, W.C.2    Manson, J.E.3
  • 43
    • 29144464971 scopus 로고    scopus 로고
    • Postmenopausal serum androgens, oestrogens and breast cancer risk: the European prospective investigation into cancer and nutrition
    • Kaaks R., Rinaldi S., Key T.J., et al. Postmenopausal serum androgens, oestrogens and breast cancer risk: the European prospective investigation into cancer and nutrition. Endocr Relat Cancer 2005, 12(4):1071-1082.
    • (2005) Endocr Relat Cancer , vol.12 , Issue.4 , pp. 1071-1082
    • Kaaks, R.1    Rinaldi, S.2    Key, T.J.3
  • 44
    • 0030512085 scopus 로고    scopus 로고
    • Aromatase inhibition for breast cancer treatment
    • Lonning P.E. Aromatase inhibition for breast cancer treatment. Acta Oncol 1996, 35(Suppl 5):38-43.
    • (1996) Acta Oncol , vol.35 , Issue.SUPPL. 5 , pp. 38-43
    • Lonning, P.E.1
  • 45
    • 0029164418 scopus 로고
    • Alcohol, height, and adiposity in relation to estrogen and prolactin levels in postmenopausal women
    • Hankinson S.E., Willett W.C., Manson J.E., et al. Alcohol, height, and adiposity in relation to estrogen and prolactin levels in postmenopausal women. J Natl Cancer Inst 1995, 87(17):1297-1302.
    • (1995) J Natl Cancer Inst , vol.87 , Issue.17 , pp. 1297-1302
    • Hankinson, S.E.1    Willett, W.C.2    Manson, J.E.3
  • 46
    • 21644448735 scopus 로고    scopus 로고
    • C-peptide, IGF-I, sex-steroid hormones and adiposity: a cross-sectional study in healthy women within the European Prospective Investigation into Cancer and Nutrition (EPIC)
    • Bezemer I.D., Rinaldi S., Dossus L., et al. C-peptide, IGF-I, sex-steroid hormones and adiposity: a cross-sectional study in healthy women within the European Prospective Investigation into Cancer and Nutrition (EPIC). Cancer Causes Control 2005, 16(5):561-572.
    • (2005) Cancer Causes Control , vol.16 , Issue.5 , pp. 561-572
    • Bezemer, I.D.1    Rinaldi, S.2    Dossus, L.3
  • 47
    • 0033362104 scopus 로고    scopus 로고
    • Leptin levels in menopause: effect of estrogen replacement therapy
    • Cento R.M., Proto C., Spada R.S., et al. Leptin levels in menopause: effect of estrogen replacement therapy. Horm Res 1999, 52(6):269-273.
    • (1999) Horm Res , vol.52 , Issue.6 , pp. 269-273
    • Cento, R.M.1    Proto, C.2    Spada, R.S.3
  • 48
    • 33749538836 scopus 로고    scopus 로고
    • Endogenous steroid hormone concentrations and risk of breast cancer among premenopausal women
    • Eliassen A.H., Missmer S.A., Tworoger S.S., et al. Endogenous steroid hormone concentrations and risk of breast cancer among premenopausal women. J Natl Cancer Inst 2006, 98(19):1406-1415.
    • (2006) J Natl Cancer Inst , vol.98 , Issue.19 , pp. 1406-1415
    • Eliassen, A.H.1    Missmer, S.A.2    Tworoger, S.S.3
  • 49
    • 57149142363 scopus 로고    scopus 로고
    • IGF binding proteins (IGFBPs) and regulation of breast cancer biology
    • Perks C.M., Holly J.M. IGF binding proteins (IGFBPs) and regulation of breast cancer biology. J Mammary Gland Biol Neoplasia 2008, 13(4):455-469.
    • (2008) J Mammary Gland Biol Neoplasia , vol.13 , Issue.4 , pp. 455-469
    • Perks, C.M.1    Holly, J.M.2
  • 50
    • 70849120946 scopus 로고    scopus 로고
    • Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease
    • Belfiore A., Frasca F., Pandini G., et al. Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease. Endocr Rev 2009, 30(6):586-623.
    • (2009) Endocr Rev , vol.30 , Issue.6 , pp. 586-623
    • Belfiore, A.1    Frasca, F.2    Pandini, G.3
  • 51
    • 2542498920 scopus 로고    scopus 로고
    • What is the contribution of obesity to the metabolic syndrome?
    • Grundy S.M. What is the contribution of obesity to the metabolic syndrome?. Endocrinol Metab Clin North Am 2004, 33(2):267-282.
    • (2004) Endocrinol Metab Clin North Am , vol.33 , Issue.2 , pp. 267-282
    • Grundy, S.M.1
  • 52
    • 0026448911 scopus 로고
    • The response of breast cancer cells to steroid and peptide growth factors
    • Godden J., Leake R., Kerr D.J. The response of breast cancer cells to steroid and peptide growth factors. Anticancer Res 1992, 12(5):1683-1688.
    • (1992) Anticancer Res , vol.12 , Issue.5 , pp. 1683-1688
    • Godden, J.1    Leake, R.2    Kerr, D.J.3
  • 53
    • 0026628745 scopus 로고
    • Effects of insulin-like growth factors (IGFs) and IGF receptor antibodies on the proliferation of human breast cancer cells
    • De Leon D.D., Wilson D.M., Powers M., et al. Effects of insulin-like growth factors (IGFs) and IGF receptor antibodies on the proliferation of human breast cancer cells. Growth Factors 1992, 6(4):327-336.
    • (1992) Growth Factors , vol.6 , Issue.4 , pp. 327-336
    • De Leon, D.D.1    Wilson, D.M.2    Powers, M.3
  • 54
    • 0025157304 scopus 로고
    • The growth hormone independent insulin-like growth factor-I binding protein BP-28 is associated with serum insulin-like growth factor-I inhibitory bioactivity in adolescent insulin-dependent diabetics
    • Taylor A.M., Dunger D.B., Preece M.A., et al. The growth hormone independent insulin-like growth factor-I binding protein BP-28 is associated with serum insulin-like growth factor-I inhibitory bioactivity in adolescent insulin-dependent diabetics. Clin Endocrinol (Oxf) 1990, 32(2):229-239.
    • (1990) Clin Endocrinol (Oxf) , vol.32 , Issue.2 , pp. 229-239
    • Taylor, A.M.1    Dunger, D.B.2    Preece, M.A.3
  • 55
    • 10944260245 scopus 로고    scopus 로고
    • Estrogen and insulin/IGF-1 cooperatively stimulate cell cycle progression in MCF-7 breast cancer cells through differential regulation of c-Myc and cyclin D1
    • Mawson A., Lai A., Carroll J.S., et al. Estrogen and insulin/IGF-1 cooperatively stimulate cell cycle progression in MCF-7 breast cancer cells through differential regulation of c-Myc and cyclin D1. Mol Cell Endocrinol 2005, 229(1-2):161-173.
    • (2005) Mol Cell Endocrinol , vol.229 , Issue.1-2 , pp. 161-173
    • Mawson, A.1    Lai, A.2    Carroll, J.S.3
  • 56
    • 0018904425 scopus 로고
    • Association between serum insulin, serum somatomedin and liver receptors for human growth hormone in streptozotocin diabetes
    • Baxter R.C., Brown A.S., Turtle J.R. Association between serum insulin, serum somatomedin and liver receptors for human growth hormone in streptozotocin diabetes. Horm Metab Res 1980, 12(8):377-381.
    • (1980) Horm Metab Res , vol.12 , Issue.8 , pp. 377-381
    • Baxter, R.C.1    Brown, A.S.2    Turtle, J.R.3
  • 57
    • 12144287363 scopus 로고    scopus 로고
    • Body mass index, circulating levels of sex-steroid hormones, IGF-I and IGF-binding protein-3: a cross-sectional study in healthy women
    • Lukanova A., Lundin E., Zeleniuch-Jacquotte A., et al. Body mass index, circulating levels of sex-steroid hormones, IGF-I and IGF-binding protein-3: a cross-sectional study in healthy women. Eur J Endocrinol 2004, 150(2):161-171.
    • (2004) Eur J Endocrinol , vol.150 , Issue.2 , pp. 161-171
    • Lukanova, A.1    Lundin, E.2    Zeleniuch-Jacquotte, A.3
  • 58
    • 0037305130 scopus 로고    scopus 로고
    • Lifestyle determinants of serum insulin-like growth-factor-I (IGF-I), C-peptide and hormone binding protein levels in British women
    • Allen N.E., Appleby P.N., Kaaks R., et al. Lifestyle determinants of serum insulin-like growth-factor-I (IGF-I), C-peptide and hormone binding protein levels in British women. Cancer Causes Control 2003, 14(1):65-74.
    • (2003) Cancer Causes Control , vol.14 , Issue.1 , pp. 65-74
    • Allen, N.E.1    Appleby, P.N.2    Kaaks, R.3
  • 59
    • 77953536809 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 (IGF1), IGF binding protein 3 (IGFBP3), and breast cancer risk: pooled individual data analysis of 17 prospective studies
    • Key T.J., Appleby P.N., Reeves G.K., et al. Insulin-like growth factor 1 (IGF1), IGF binding protein 3 (IGFBP3), and breast cancer risk: pooled individual data analysis of 17 prospective studies. Lancet Oncol 2010, 11(6):530-542.
    • (2010) Lancet Oncol , vol.11 , Issue.6 , pp. 530-542
    • Key, T.J.1    Appleby, P.N.2    Reeves, G.K.3
  • 60
    • 0034974302 scopus 로고    scopus 로고
    • IGF-I receptor signalling in transformation and differentiation
    • Valentinis B., Baserga R. IGF-I receptor signalling in transformation and differentiation. Mol Pathol 2001, 54(3):133-137.
    • (2001) Mol Pathol , vol.54 , Issue.3 , pp. 133-137
    • Valentinis, B.1    Baserga, R.2
  • 61
    • 0032827420 scopus 로고    scopus 로고
    • Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis
    • Peruzzi F., Prisco M., Dews M., et al. Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis. Mol Cell Biol 1999, 19(10):7203-7215.
    • (1999) Mol Cell Biol , vol.19 , Issue.10 , pp. 7203-7215
    • Peruzzi, F.1    Prisco, M.2    Dews, M.3
  • 62
    • 0037292936 scopus 로고    scopus 로고
    • Role of the IGF-I receptor in the regulation of cell-cell adhesion: implications in cancer development and progression
    • Mauro L., Salerno M., Morelli C., et al. Role of the IGF-I receptor in the regulation of cell-cell adhesion: implications in cancer development and progression. J Cell Physiol 2003, 194(2):108-116.
    • (2003) J Cell Physiol , vol.194 , Issue.2 , pp. 108-116
    • Mauro, L.1    Salerno, M.2    Morelli, C.3
  • 63
    • 0030028186 scopus 로고    scopus 로고
    • The roles of integrins and extracellular matrix proteins in the insulin-like growth factor I-stimulated chemotaxis of human breast cancer cells
    • Doerr M.E., Jones J.I. The roles of integrins and extracellular matrix proteins in the insulin-like growth factor I-stimulated chemotaxis of human breast cancer cells. J Biol Chem 1996, 271(5):2443-2447.
    • (1996) J Biol Chem , vol.271 , Issue.5 , pp. 2443-2447
    • Doerr, M.E.1    Jones, J.I.2
  • 64
    • 1842833905 scopus 로고    scopus 로고
    • Functional role of alpha-actinin, PI 3-kinase and MEK1/2 in insulin-like growth factor I receptor kinase regulated motility of human breast carcinoma cells
    • Guvakova M.A., Adams J.C., Boettiger D. Functional role of alpha-actinin, PI 3-kinase and MEK1/2 in insulin-like growth factor I receptor kinase regulated motility of human breast carcinoma cells. J Cell Sci 2002, 115(Pt 21):4149-4165.
    • (2002) J Cell Sci , vol.115 , Issue.PART 21 , pp. 4149-4165
    • Guvakova, M.A.1    Adams, J.C.2    Boettiger, D.3
  • 65
    • 0028914715 scopus 로고
    • Hydrocortisone and progesterone regulation of the proliferation, morphogenesis, and functional differentiation of normal rat mammary epithelial cells in three dimensional primary culture
    • Darcy K.M., Shoemaker S.F., Lee P.P., et al. Hydrocortisone and progesterone regulation of the proliferation, morphogenesis, and functional differentiation of normal rat mammary epithelial cells in three dimensional primary culture. J Cell Physiol 1995, 163(2):365-379.
    • (1995) J Cell Physiol , vol.163 , Issue.2 , pp. 365-379
    • Darcy, K.M.1    Shoemaker, S.F.2    Lee, P.P.3
  • 66
    • 70449255204 scopus 로고
    • Hormonal synergism in mammary growth
    • Lyons W.R. Hormonal synergism in mammary growth. Proc R Soc Lond B Biol Sci 1958, 149(936):303-325.
    • (1958) Proc R Soc Lond B Biol Sci , vol.149 , Issue.936 , pp. 303-325
    • Lyons, W.R.1
  • 67
    • 0027517558 scopus 로고
    • Glucocorticoids induce a G1/G0 cell cycle arrest of Con8 rat mammary tumor cells that is synchronously reversed by steroid withdrawal or addition of transforming growth factor-alpha
    • Goya L., Maiyar A.C., Ge Y., et al. Glucocorticoids induce a G1/G0 cell cycle arrest of Con8 rat mammary tumor cells that is synchronously reversed by steroid withdrawal or addition of transforming growth factor-alpha. Mol Endocrinol 1993, 7(9):1121-1132.
    • (1993) Mol Endocrinol , vol.7 , Issue.9 , pp. 1121-1132
    • Goya, L.1    Maiyar, A.C.2    Ge, Y.3
  • 68
    • 54749155579 scopus 로고    scopus 로고
    • Glucocorticoids antagonize estrogens by glucocorticoid receptor-mediated activation of estrogen sulfotransferase
    • Gong H., Jarzynka M.J., Cole T.J., et al. Glucocorticoids antagonize estrogens by glucocorticoid receptor-mediated activation of estrogen sulfotransferase. Cancer Res 2008, 68(18):7386-7393.
    • (2008) Cancer Res , vol.68 , Issue.18 , pp. 7386-7393
    • Gong, H.1    Jarzynka, M.J.2    Cole, T.J.3
  • 69
    • 33751167213 scopus 로고    scopus 로고
    • Dexamethasone decreases xenograft response to Paclitaxel through inhibition of tumor cell apoptosis
    • Pang D., Kocherginsky M., Krausz T., et al. Dexamethasone decreases xenograft response to Paclitaxel through inhibition of tumor cell apoptosis. Cancer Biol Ther 2006, 5(8):933-940.
    • (2006) Cancer Biol Ther , vol.5 , Issue.8 , pp. 933-940
    • Pang, D.1    Kocherginsky, M.2    Krausz, T.3
  • 70
    • 80052764695 scopus 로고    scopus 로고
    • Expression of 11beta-hydroxysteroid Dehydrogenase Type 1 in Breast cancer and adjacent non-malignant tissue. An Immunocytochemical Study
    • [Epub ahead of print]
    • Lu L., Zhao G., Luu-The V., et al. Expression of 11beta-hydroxysteroid Dehydrogenase Type 1 in Breast cancer and adjacent non-malignant tissue. An Immunocytochemical Study. Pathol Oncol Res 2011, [Epub ahead of print].
    • (2011) Pathol Oncol Res
    • Lu, L.1    Zhao, G.2    Luu-The, V.3
  • 71
    • 57149123434 scopus 로고    scopus 로고
    • Genetic variation in candidate obesity genes ADRB2, ADRB3, GHRL, HSD11B1, IRS1, IRS2, and SHC1 and risk for breast cancer in the Cancer Prevention Study II
    • Feigelson H.S., Teras L.R., Diver W.R., et al. Genetic variation in candidate obesity genes ADRB2, ADRB3, GHRL, HSD11B1, IRS1, IRS2, and SHC1 and risk for breast cancer in the Cancer Prevention Study II. Breast Cancer Res 2008, 10(4):R57.
    • (2008) Breast Cancer Res , vol.10 , Issue.4
    • Feigelson, H.S.1    Teras, L.R.2    Diver, W.R.3
  • 72
    • 0029618368 scopus 로고
    • Steroid hormone receptors: many actors in search of a plot
    • Beato M., Herrlich P., Schutz G. Steroid hormone receptors: many actors in search of a plot. Cell 1995, 83(6):851-857.
    • (1995) Cell , vol.83 , Issue.6 , pp. 851-857
    • Beato, M.1    Herrlich, P.2    Schutz, G.3
  • 73
    • 33745712783 scopus 로고    scopus 로고
    • Differential expression of glucocorticoid receptor in human breast tissues and related neoplasms
    • Lien H.C., Lu Y.S., Cheng A.L., et al. Differential expression of glucocorticoid receptor in human breast tissues and related neoplasms. J Pathol 2006, 209(3):317-327.
    • (2006) J Pathol , vol.209 , Issue.3 , pp. 317-327
    • Lien, H.C.1    Lu, Y.S.2    Cheng, A.L.3
  • 74
    • 0036324073 scopus 로고    scopus 로고
    • Tissue-specific changes in peripheral cortisol metabolism in obese women: increased adipose 11beta-hydroxysteroid dehydrogenase type 1 activity
    • Rask E., Walker B.R., Soderberg S., et al. Tissue-specific changes in peripheral cortisol metabolism in obese women: increased adipose 11beta-hydroxysteroid dehydrogenase type 1 activity. J Clin Endocrinol Metab 2002, 87(7):3330-3336.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.7 , pp. 3330-3336
    • Rask, E.1    Walker, B.R.2    Soderberg, S.3
  • 75
    • 40349090041 scopus 로고    scopus 로고
    • Glucocorticoids and 11beta-hydroxysteroid dehydrogenase type 1 in obesity and the metabolic syndrome
    • Stimson R.H., Walker B.R. Glucocorticoids and 11beta-hydroxysteroid dehydrogenase type 1 in obesity and the metabolic syndrome. Minerva Endocrinol 2007, 32(3):141-159.
    • (2007) Minerva Endocrinol , vol.32 , Issue.3 , pp. 141-159
    • Stimson, R.H.1    Walker, B.R.2
  • 76
    • 33746865283 scopus 로고    scopus 로고
    • One ancestor, several peptides post-translational modifications of preproghrelin generate several peptides with antithetical effects
    • Gualillo O., Lago F., Casanueva F.F., et al. One ancestor, several peptides post-translational modifications of preproghrelin generate several peptides with antithetical effects. Mol Cell Endocrinol 2006, 256(1-2):1-8.
    • (2006) Mol Cell Endocrinol , vol.256 , Issue.1-2 , pp. 1-8
    • Gualillo, O.1    Lago, F.2    Casanueva, F.F.3
  • 77
    • 0034808754 scopus 로고    scopus 로고
    • Growth hormone (GH)-independent stimulation of adiposity by GH secretagogues
    • Lall S., Tung L.Y., Ohlsson C., et al. Growth hormone (GH)-independent stimulation of adiposity by GH secretagogues. Biochem Biophys Res Commun 2001, 280(1):132-138.
    • (2001) Biochem Biophys Res Commun , vol.280 , Issue.1 , pp. 132-138
    • Lall, S.1    Tung, L.Y.2    Ohlsson, C.3
  • 78
    • 0034687376 scopus 로고    scopus 로고
    • Ghrelin induces adiposity in rodents
    • Tschop M., Smiley D.L., Heiman M.L. Ghrelin induces adiposity in rodents. Nature 2000, 407(6806):908-913.
    • (2000) Nature , vol.407 , Issue.6806 , pp. 908-913
    • Tschop, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 79
    • 77954159575 scopus 로고    scopus 로고
    • The ghrelin/obestatin balance in the physiological and pathological control of growth hormone secretion, body composition and food intake
    • Hassouna R., Zizzari P., Tolle V. The ghrelin/obestatin balance in the physiological and pathological control of growth hormone secretion, body composition and food intake. J Neuroendocrinol 2010, 22(7):793-804.
    • (2010) J Neuroendocrinol , vol.22 , Issue.7 , pp. 793-804
    • Hassouna, R.1    Zizzari, P.2    Tolle, V.3
  • 80
    • 58149522922 scopus 로고    scopus 로고
    • Is GPR39 the natural receptor of obestatin?
    • Dong X.Y., He J.M., Tang S.Q., et al. Is GPR39 the natural receptor of obestatin?. Peptides 2009, 30(2):431-438.
    • (2009) Peptides , vol.30 , Issue.2 , pp. 431-438
    • Dong, X.Y.1    He, J.M.2    Tang, S.Q.3
  • 81
    • 3042735648 scopus 로고    scopus 로고
    • The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans
    • Gnanapavan S., Kola B., Bustin S.A., et al. The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans. J Clin Endocrinol Metab 2002, 87(6):2988.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.6 , pp. 2988
    • Gnanapavan, S.1    Kola, B.2    Bustin, S.A.3
  • 82
    • 33746781251 scopus 로고    scopus 로고
    • Ghrelin and cholecystokinin in term and preterm human breast milk
    • Kierson J.A., Dimatteo D.M., Locke R.G., et al. Ghrelin and cholecystokinin in term and preterm human breast milk. Acta Paediatr 2006, 95(8):991-995.
    • (2006) Acta Paediatr , vol.95 , Issue.8 , pp. 991-995
    • Kierson, J.A.1    Dimatteo, D.M.2    Locke, R.G.3
  • 83
    • 17744396454 scopus 로고    scopus 로고
    • Identification, characterization, and biological activity of specific receptors for natural (ghrelin) and synthetic growth hormone secretagogues and analogs in human breast carcinomas and cell lines
    • Cassoni P., Papotti M., Ghe C., et al. Identification, characterization, and biological activity of specific receptors for natural (ghrelin) and synthetic growth hormone secretagogues and analogs in human breast carcinomas and cell lines. J Clin Endocrinol Metab 2001, 86(4):1738-1745.
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.4 , pp. 1738-1745
    • Cassoni, P.1    Papotti, M.2    Ghe, C.3
  • 84
    • 28544446509 scopus 로고    scopus 로고
    • Expression and function of the ghrelin axis, including a novel preproghrelin isoform, in human breast cancer tissues and cell lines
    • Jeffery P.L., Murray R.E., Yeh A.H., et al. Expression and function of the ghrelin axis, including a novel preproghrelin isoform, in human breast cancer tissues and cell lines. Endocr Relat Cancer 2005, 12(4):839-850.
    • (2005) Endocr Relat Cancer , vol.12 , Issue.4 , pp. 839-850
    • Jeffery, P.L.1    Murray, R.E.2    Yeh, A.H.3
  • 85
    • 49349111720 scopus 로고    scopus 로고
    • Polymorphisms of genes coding for ghrelin and its receptor in relation to anthropometry, circulating levels of IGF-I and IGFBP-3, and breast cancer risk: a case-control study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC)
    • Dossus L., McKay J.D., Canzian F., et al. Polymorphisms of genes coding for ghrelin and its receptor in relation to anthropometry, circulating levels of IGF-I and IGFBP-3, and breast cancer risk: a case-control study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC). Carcinogenesis 2008, 29(7):1360-1366.
    • (2008) Carcinogenesis , vol.29 , Issue.7 , pp. 1360-1366
    • Dossus, L.1    McKay, J.D.2    Canzian, F.3
  • 86
    • 0035082265 scopus 로고    scopus 로고
    • Circulating ghrelin levels are decreased in human obesity
    • Tschop M., Weyer C., Tataranni P.A., et al. Circulating ghrelin levels are decreased in human obesity. Diabetes 2001, 50(4):707-709.
    • (2001) Diabetes , vol.50 , Issue.4 , pp. 707-709
    • Tschop, M.1    Weyer, C.2    Tataranni, P.A.3
  • 87
    • 0037162116 scopus 로고    scopus 로고
    • Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery
    • Cummings D.E., Weigle D.S., Frayo R.S., et al. Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery. N Engl J Med 2002, 346(21):1623-1630.
    • (2002) N Engl J Med , vol.346 , Issue.21 , pp. 1623-1630
    • Cummings, D.E.1    Weigle, D.S.2    Frayo, R.S.3
  • 88
    • 78651329957 scopus 로고    scopus 로고
    • Meta-analysis of the relationship between obestatin and ghrelin levels and the ghrelin/obestatin ratio with respect to obesity
    • Zhang N., Yuan C., Li Z., et al. Meta-analysis of the relationship between obestatin and ghrelin levels and the ghrelin/obestatin ratio with respect to obesity. Am J Med Sci 2011, 341(1):48-55.
    • (2011) Am J Med Sci , vol.341 , Issue.1 , pp. 48-55
    • Zhang, N.1    Yuan, C.2    Li, Z.3
  • 89
    • 35349031642 scopus 로고    scopus 로고
    • Circulating obestatin levels and the ghrelin/obestatin ratio in obese women
    • Vicennati V., Genghini S., De Iasio R., et al. Circulating obestatin levels and the ghrelin/obestatin ratio in obese women. Eur J Endocrinol 2007, 157(3):295-301.
    • (2007) Eur J Endocrinol , vol.157 , Issue.3 , pp. 295-301
    • Vicennati, V.1    Genghini, S.2    De Iasio, R.3
  • 90
    • 0141892161 scopus 로고    scopus 로고
    • Mature adipocytes, but not preadipocytes, promote the growth of breast carcinoma cells in collagen gel matrix culture through cancer-stromal cell interactions
    • Manabe Y., Toda S., Miyazaki K., et al. Mature adipocytes, but not preadipocytes, promote the growth of breast carcinoma cells in collagen gel matrix culture through cancer-stromal cell interactions. J Pathol 2003, 201(2):221-228.
    • (2003) J Pathol , vol.201 , Issue.2 , pp. 221-228
    • Manabe, Y.1    Toda, S.2    Miyazaki, K.3
  • 91
    • 20944447217 scopus 로고    scopus 로고
    • Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment
    • Iyengar P., Espina V., Williams T.W., et al. Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment. J Clin Invest 2005, 115(5):1163-1176.
    • (2005) J Clin Invest , vol.115 , Issue.5 , pp. 1163-1176
    • Iyengar, P.1    Espina, V.2    Williams, T.W.3
  • 92
    • 70449353716 scopus 로고    scopus 로고
    • Adipocyte culture medium stimulates invasiveness of MDA-MB-231 cell via CCL20 production
    • Kim K.Y., Baek A., Park Y.S., et al. Adipocyte culture medium stimulates invasiveness of MDA-MB-231 cell via CCL20 production. Oncol Rep 2009, 22(6):1497-1504.
    • (2009) Oncol Rep , vol.22 , Issue.6 , pp. 1497-1504
    • Kim, K.Y.1    Baek, A.2    Park, Y.S.3
  • 93
    • 43149112727 scopus 로고    scopus 로고
    • Mammographic density. Potential mechanisms of breast cancer risk associated with mammographic density: hypotheses based on epidemiological evidence
    • Martin L.J., Boyd N.F. Mammographic density. Potential mechanisms of breast cancer risk associated with mammographic density: hypotheses based on epidemiological evidence. Breast Cancer Res 2008, 10(1):201.
    • (2008) Breast Cancer Res , vol.10 , Issue.1 , pp. 201
    • Martin, L.J.1    Boyd, N.F.2
  • 94
    • 32944466760 scopus 로고    scopus 로고
    • Modulation of aromatase expression by BRCA1: a possible link to tissue-specific tumor suppression
    • Hu Y., Ghosh S., Amleh A., et al. Modulation of aromatase expression by BRCA1: a possible link to tissue-specific tumor suppression. Oncogene 2005, 24(56):8343-8348.
    • (2005) Oncogene , vol.24 , Issue.56 , pp. 8343-8348
    • Hu, Y.1    Ghosh, S.2    Amleh, A.3
  • 95
    • 77957261038 scopus 로고    scopus 로고
    • Is mammographic breast density a breast cancer risk factor in women with BRCA mutations?
    • Passaperuma K., Warner E., Hill K.A., et al. Is mammographic breast density a breast cancer risk factor in women with BRCA mutations?. J Clin Oncol 2010, 28(23):3779-3783.
    • (2010) J Clin Oncol , vol.28 , Issue.23 , pp. 3779-3783
    • Passaperuma, K.1    Warner, E.2    Hill, K.A.3
  • 96
    • 0027065037 scopus 로고
    • Identification of a protein factor secreted by 3T3-L1 preadipocytes inhibitory for the human MCF-7 breast cancer cell line
    • Johnston P.G., Rondinone C.M., Voeller D., et al. Identification of a protein factor secreted by 3T3-L1 preadipocytes inhibitory for the human MCF-7 breast cancer cell line. Cancer Res 1992, 52(24):6860-6865.
    • (1992) Cancer Res , vol.52 , Issue.24 , pp. 6860-6865
    • Johnston, P.G.1    Rondinone, C.M.2    Voeller, D.3
  • 97
    • 0032447602 scopus 로고    scopus 로고
    • Preadipocytes stimulate breast cancer cell growth
    • Chamras H., Bagga D., Elstner E., et al. Preadipocytes stimulate breast cancer cell growth. Nutr Cancer 1998, 32(2):59-63.
    • (1998) Nutr Cancer , vol.32 , Issue.2 , pp. 59-63
    • Chamras, H.1    Bagga, D.2    Elstner, E.3
  • 98
    • 0031436148 scopus 로고    scopus 로고
    • Divergent signaling capacities of the long and short isoforms of the leptin receptor
    • Bjorbaek C., Uotani S., da Silva B., et al. Divergent signaling capacities of the long and short isoforms of the leptin receptor. J Biol Chem 1997, 272(51):32686-32695.
    • (1997) J Biol Chem , vol.272 , Issue.51 , pp. 32686-32695
    • Bjorbaek, C.1    Uotani, S.2    da Silva, B.3
  • 99
    • 44649105662 scopus 로고    scopus 로고
    • Dietary xenoestrogens differentially impair 3T3-L1 preadipocyte differentiation and persistently affect leptin synthesis
    • Phrakonkham P., Viengchareun S., Belloir C., et al. Dietary xenoestrogens differentially impair 3T3-L1 preadipocyte differentiation and persistently affect leptin synthesis. J Steroid Biochem Mol Biol 2008, 110(1-2):95-103.
    • (2008) J Steroid Biochem Mol Biol , vol.110 , Issue.1-2 , pp. 95-103
    • Phrakonkham, P.1    Viengchareun, S.2    Belloir, C.3
  • 100
    • 20444470367 scopus 로고    scopus 로고
    • Obesity and longevity
    • [author reply: 2556-7]
    • Simon P.A., Frye D.M. Obesity and longevity. N Engl J Med 2005, 352(24):2555. [author reply: 2556-7].
    • (2005) N Engl J Med , vol.352 , Issue.24 , pp. 2555
    • Simon, P.A.1    Frye, D.M.2
  • 101
    • 0031724837 scopus 로고    scopus 로고
    • Leptin expression in human mammary epithelial cells and breast milk
    • Smith-Kirwin S.M., O'Connor D.M., De Johnston J., et al. Leptin expression in human mammary epithelial cells and breast milk. J Clin Endocrinol Metab 1998, 83(5):1810-1813.
    • (1998) J Clin Endocrinol Metab , vol.83 , Issue.5 , pp. 1810-1813
    • Smith-Kirwin, S.M.1    O'Connor, D.M.2    De Johnston, J.3
  • 102
    • 0029896530 scopus 로고    scopus 로고
    • Role of leptin in the neuroendocrine response to fasting
    • Ahima R.S., Prabakaran D., Mantzoros C., et al. Role of leptin in the neuroendocrine response to fasting. Nature 1996, 382(6588):250-252.
    • (1996) Nature , vol.382 , Issue.6588 , pp. 250-252
    • Ahima, R.S.1    Prabakaran, D.2    Mantzoros, C.3
  • 103
    • 0028825577 scopus 로고
    • Recombinant ob protein reduces feeding and body weight in the ob/ob mouse
    • Weigle D.S., Bukowski T.R., Foster D.C., et al. Recombinant ob protein reduces feeding and body weight in the ob/ob mouse. J Clin Invest 1995, 96(4):2065-2070.
    • (1995) J Clin Invest , vol.96 , Issue.4 , pp. 2065-2070
    • Weigle, D.S.1    Bukowski, T.R.2    Foster, D.C.3
  • 104
    • 0030878110 scopus 로고    scopus 로고
    • Congenital leptin deficiency is associated with severe early-onset obesity in humans
    • Montague C.T., Farooqi I.S., Whitehead J.P., et al. Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 1997, 387(6636):903-908.
    • (1997) Nature , vol.387 , Issue.6636 , pp. 903-908
    • Montague, C.T.1    Farooqi, I.S.2    Whitehead, J.P.3
  • 105
    • 0030160429 scopus 로고    scopus 로고
    • Leptin in humans: current progress and future directions
    • Considine R.V., Caro J.F. Leptin in humans: current progress and future directions. Clin Chem 1996, 42(6 Pt 1):843-844.
    • (1996) Clin Chem , vol.42 , Issue.6 PART 1 , pp. 843-844
    • Considine, R.V.1    Caro, J.F.2
  • 106
    • 0028845877 scopus 로고
    • Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
    • Maffei M., Halaas J., Ravussin E., et al. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1995, 1(11):1155-1161.
    • (1995) Nat Med , vol.1 , Issue.11 , pp. 1155-1161
    • Maffei, M.1    Halaas, J.2    Ravussin, E.3
  • 107
    • 0036289490 scopus 로고    scopus 로고
    • Leptin mediates a proliferative response in human MCF7 breast cancer cells
    • Dieudonne M.N., Machinal-Quelin F., Serazin-Leroy V., et al. Leptin mediates a proliferative response in human MCF7 breast cancer cells. Biochem Biophys Res Commun 2002, 293(1):622-628.
    • (2002) Biochem Biophys Res Commun , vol.293 , Issue.1 , pp. 622-628
    • Dieudonne, M.N.1    Machinal-Quelin, F.2    Serazin-Leroy, V.3
  • 108
    • 70449635843 scopus 로고    scopus 로고
    • Obesity and the associated mediators leptin, estrogen and IGF-I enhance the cell proliferation and early tumorigenesis of breast cancer cells
    • Lautenbach A., Budde A., Wrann C.D., et al. Obesity and the associated mediators leptin, estrogen and IGF-I enhance the cell proliferation and early tumorigenesis of breast cancer cells. Nutr Cancer 2009, 61(4):484-491.
    • (2009) Nutr Cancer , vol.61 , Issue.4 , pp. 484-491
    • Lautenbach, A.1    Budde, A.2    Wrann, C.D.3
  • 109
    • 77957743528 scopus 로고    scopus 로고
    • Leptin potentiates antiproliferative action of cAMP elevation via protein kinase A down-regulation in breast cancer cells
    • Naviglio S., Di Gesto D., Illiano F., et al. Leptin potentiates antiproliferative action of cAMP elevation via protein kinase A down-regulation in breast cancer cells. J Cell Physiol 2010, 225(3):801-809.
    • (2010) J Cell Physiol , vol.225 , Issue.3 , pp. 801-809
    • Naviglio, S.1    Di Gesto, D.2    Illiano, F.3
  • 110
    • 39149104963 scopus 로고    scopus 로고
    • Upregulation of survivin by leptin/STAT3 signaling in MCF-7 cells
    • Jiang H., Yu J., Guo H., et al. Upregulation of survivin by leptin/STAT3 signaling in MCF-7 cells. Biochem Biophys Res Commun 2008, 368(1):1-5.
    • (2008) Biochem Biophys Res Commun , vol.368 , Issue.1 , pp. 1-5
    • Jiang, H.1    Yu, J.2    Guo, H.3
  • 111
    • 77953704226 scopus 로고    scopus 로고
    • Leptin upregulates VEGF in breast cancer via canonic and non-canonical signalling pathways and NFkappaB/HIF-1alpha activation
    • Gonzalez-Perez R.R., Xu Y., Guo S., et al. Leptin upregulates VEGF in breast cancer via canonic and non-canonical signalling pathways and NFkappaB/HIF-1alpha activation. Cell Signal 2010, 22(9):1350-1362.
    • (2010) Cell Signal , vol.22 , Issue.9 , pp. 1350-1362
    • Gonzalez-Perez, R.R.1    Xu, Y.2    Guo, S.3
  • 112
    • 77949875577 scopus 로고    scopus 로고
    • Leptin upregulates telomerase activity and transcription of human telomerase reverse transcriptase in MCF-7 breast cancer cells
    • Ren H., Zhao T., Wang X., et al. Leptin upregulates telomerase activity and transcription of human telomerase reverse transcriptase in MCF-7 breast cancer cells. Biochem Biophys Res Commun 2010, 394(1):59-63.
    • (2010) Biochem Biophys Res Commun , vol.394 , Issue.1 , pp. 59-63
    • Ren, H.1    Zhao, T.2    Wang, X.3
  • 113
    • 48949091209 scopus 로고    scopus 로고
    • Leptin augments proliferation of breast cancer cells via transactivation of HER2
    • Soma D., Kitayama J., Yamashita H., et al. Leptin augments proliferation of breast cancer cells via transactivation of HER2. J Surg Res 2008, 149(1):9-14.
    • (2008) J Surg Res , vol.149 , Issue.1 , pp. 9-14
    • Soma, D.1    Kitayama, J.2    Yamashita, H.3
  • 114
    • 77954420709 scopus 로고    scopus 로고
    • Tissue leptin levels in patients with breast cancer
    • Karaduman M., Bilici A., Ozet A., et al. Tissue leptin levels in patients with breast cancer. J BUON 2010, 15(2):369-372.
    • (2010) J BUON , vol.15 , Issue.2 , pp. 369-372
    • Karaduman, M.1    Bilici, A.2    Ozet, A.3
  • 115
    • 3042817487 scopus 로고    scopus 로고
    • Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer
    • Ishikawa M., Kitayama J., Nagawa H. Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer. Clin Cancer Res 2004, 10(13):4325-4331.
    • (2004) Clin Cancer Res , vol.10 , Issue.13 , pp. 4325-4331
    • Ishikawa, M.1    Kitayama, J.2    Nagawa, H.3
  • 116
    • 74549206116 scopus 로고    scopus 로고
    • Overexpression of leptin and leptin receptors in breast cancer positively correlates with clinicopathological features
    • Xia X.H., Gu J.C., Bai Q.Y., et al. Overexpression of leptin and leptin receptors in breast cancer positively correlates with clinicopathological features. Chin Med J (Engl) 2009, 122(24):3078-3081.
    • (2009) Chin Med J (Engl) , vol.122 , Issue.24 , pp. 3078-3081
    • Xia, X.H.1    Gu, J.C.2    Bai, Q.Y.3
  • 117
    • 43849103666 scopus 로고    scopus 로고
    • Leptin and leptin receptor involvement in cancer development: a study on human primary breast carcinoma
    • Jarde T., Caldefie-Chezet F., Damez M., et al. Leptin and leptin receptor involvement in cancer development: a study on human primary breast carcinoma. Oncol Rep 2008, 19(4):905-911.
    • (2008) Oncol Rep , vol.19 , Issue.4 , pp. 905-911
    • Jarde, T.1    Caldefie-Chezet, F.2    Damez, M.3
  • 118
    • 74849087406 scopus 로고    scopus 로고
    • Adipocyte fatty acid-binding protein as a novel prognostic factor in obese breast cancer patients
    • Hancke K., Grubeck D., Hauser N., et al. Adipocyte fatty acid-binding protein as a novel prognostic factor in obese breast cancer patients. Breast Cancer Res Treat 2010, 119(2):367-377.
    • (2010) Breast Cancer Res Treat , vol.119 , Issue.2 , pp. 367-377
    • Hancke, K.1    Grubeck, D.2    Hauser, N.3
  • 119
    • 33745914266 scopus 로고    scopus 로고
    • Interrelationships between serum leptin, IGF-1, IGFBP3, C-peptide and prolactin and breast cancer risk in young women
    • Falk R.T., Brinton L.A., Madigan M.P., et al. Interrelationships between serum leptin, IGF-1, IGFBP3, C-peptide and prolactin and breast cancer risk in young women. Breast Cancer Res Treat 2006, 98(2):157-165.
    • (2006) Breast Cancer Res Treat , vol.98 , Issue.2 , pp. 157-165
    • Falk, R.T.1    Brinton, L.A.2    Madigan, M.P.3
  • 120
    • 0034087951 scopus 로고    scopus 로고
    • Leptin and insulin growth factor I in relation to breast cancer (Greece)
    • Petridou E., Papadiamantis Y., Markopoulos C., et al. Leptin and insulin growth factor I in relation to breast cancer (Greece). Cancer Causes Control 2000, 11(5):383-388.
    • (2000) Cancer Causes Control , vol.11 , Issue.5 , pp. 383-388
    • Petridou, E.1    Papadiamantis, Y.2    Markopoulos, C.3
  • 121
    • 4043133068 scopus 로고    scopus 로고
    • Plasma leptin and breast cancer risk: a prospective study in northern Sweden
    • Stattin P., Soderberg S., Biessy C., et al. Plasma leptin and breast cancer risk: a prospective study in northern Sweden. Breast Cancer Res Treat 2004, 86(3):191-196.
    • (2004) Breast Cancer Res Treat , vol.86 , Issue.3 , pp. 191-196
    • Stattin, P.1    Soderberg, S.2    Biessy, C.3
  • 122
    • 70349317352 scopus 로고    scopus 로고
    • No association between polymorphisms in LEP, LEPR, ADIPOQ, ADIPOR1, or ADIPOR2 and postmenopausal breast cancer risk
    • Teras L.R., Goodman M., Patel A.V., et al. No association between polymorphisms in LEP, LEPR, ADIPOQ, ADIPOR1, or ADIPOR2 and postmenopausal breast cancer risk. Cancer Epidemiol Biomarkers Prev 2009, 18(9):2553-2557.
    • (2009) Cancer Epidemiol Biomarkers Prev , vol.18 , Issue.9 , pp. 2553-2557
    • Teras, L.R.1    Goodman, M.2    Patel, A.V.3
  • 123
    • 77950857617 scopus 로고    scopus 로고
    • Common genetic variations in the LEP and LEPR genes, obesity and breast cancer incidence and survival
    • Cleveland R.J., Gammon M.D., Long C.M., et al. Common genetic variations in the LEP and LEPR genes, obesity and breast cancer incidence and survival. Breast Cancer Res Treat 2010, 120(3):745-752.
    • (2010) Breast Cancer Res Treat , vol.120 , Issue.3 , pp. 745-752
    • Cleveland, R.J.1    Gammon, M.D.2    Long, C.M.3
  • 124
    • 67650070739 scopus 로고    scopus 로고
    • Functional analysis of the -2548G/A leptin gene polymorphism in breast cancer cells
    • Terrasi M., Fiorio E., Mercanti A., et al. Functional analysis of the -2548G/A leptin gene polymorphism in breast cancer cells. Int J Cancer 2009, 125(5):1038-1044.
    • (2009) Int J Cancer , vol.125 , Issue.5 , pp. 1038-1044
    • Terrasi, M.1    Fiorio, E.2    Mercanti, A.3
  • 125
    • 37049024956 scopus 로고    scopus 로고
    • The roles of serum leptin concentration and polymorphism in leptin receptor gene at codon 109 in breast cancer
    • Liu C.L., Chang Y.C., Cheng S.P., et al. The roles of serum leptin concentration and polymorphism in leptin receptor gene at codon 109 in breast cancer. Oncology 2007, 72(1-2):75-81.
    • (2007) Oncology , vol.72 , Issue.1-2 , pp. 75-81
    • Liu, C.L.1    Chang, Y.C.2    Cheng, S.P.3
  • 126
    • 0037356826 scopus 로고    scopus 로고
    • The role of the novel adipocyte-derived hormone adiponectin in human disease
    • Diez J.J., Iglesias P. The role of the novel adipocyte-derived hormone adiponectin in human disease. Eur J Endocrinol 2003, 148(3):293-300.
    • (2003) Eur J Endocrinol , vol.148 , Issue.3 , pp. 293-300
    • Diez, J.J.1    Iglesias, P.2
  • 127
    • 0037494960 scopus 로고    scopus 로고
    • Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
    • Yamauchi T., Kamon J., Ito Y., et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 2003, 423(6941):762-769.
    • (2003) Nature , vol.423 , Issue.6941 , pp. 762-769
    • Yamauchi, T.1    Kamon, J.2    Ito, Y.3
  • 128
    • 40249106432 scopus 로고    scopus 로고
    • Adiponectin effects on human breast cancer cells are dependent on 17-beta estradiol
    • Pfeiler G.H., Buechler C., Neumeier M., et al. Adiponectin effects on human breast cancer cells are dependent on 17-beta estradiol. Oncol Rep 2008, 19(3):787-793.
    • (2008) Oncol Rep , vol.19 , Issue.3 , pp. 787-793
    • Pfeiler, G.H.1    Buechler, C.2    Neumeier, M.3
  • 129
    • 0037677604 scopus 로고    scopus 로고
    • Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-alpha expression
    • Kern P.A., Di Gregorio G.B., Lu T., et al. Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-alpha expression. Diabetes 2003, 52(7):1779-1785.
    • (2003) Diabetes , vol.52 , Issue.7 , pp. 1779-1785
    • Kern, P.A.1    Di Gregorio, G.B.2    Lu, T.3
  • 130
    • 0345060444 scopus 로고    scopus 로고
    • Association of serum adiponectin levels with breast cancer risk
    • Miyoshi Y., Funahashi T., Kihara S., et al. Association of serum adiponectin levels with breast cancer risk. Clin Cancer Res 2003, 9(15):5699-5704.
    • (2003) Clin Cancer Res , vol.9 , Issue.15 , pp. 5699-5704
    • Miyoshi, Y.1    Funahashi, T.2    Kihara, S.3
  • 131
    • 77955791988 scopus 로고    scopus 로고
    • Roles of adiposity, lifetime physical activity and serum adiponectin in occurrence of breast cancer among Malaysian women in Klang Valley
    • Shahar S., Salleh R.M., Ghazali A.R., et al. Roles of adiposity, lifetime physical activity and serum adiponectin in occurrence of breast cancer among Malaysian women in Klang Valley. Asian Pac J Cancer Prev 2010, 11(1):61-66.
    • (2010) Asian Pac J Cancer Prev , vol.11 , Issue.1 , pp. 61-66
    • Shahar, S.1    Salleh, R.M.2    Ghazali, A.R.3
  • 132
    • 33646497663 scopus 로고    scopus 로고
    • Serum adiponectin and leptin levels in Taiwanese breast cancer patients
    • Chen D.C., Chung Y.F., Yeh Y.T., et al. Serum adiponectin and leptin levels in Taiwanese breast cancer patients. Cancer Lett 2006, 237(1):109-114.
    • (2006) Cancer Lett , vol.237 , Issue.1 , pp. 109-114
    • Chen, D.C.1    Chung, Y.F.2    Yeh, Y.T.3
  • 134
    • 33947520304 scopus 로고    scopus 로고
    • Total and high-molecular-weight adiponectin in breast cancer: in vitro and in vivo studies
    • Korner A., Pazaitou-Panayiotou K., Kelesidis T., et al. Total and high-molecular-weight adiponectin in breast cancer: in vitro and in vivo studies. J Clin Endocrinol Metab 2007, 92(3):1041-1048.
    • (2007) J Clin Endocrinol Metab , vol.92 , Issue.3 , pp. 1041-1048
    • Korner, A.1    Pazaitou-Panayiotou, K.2    Kelesidis, T.3
  • 135
    • 77957230259 scopus 로고    scopus 로고
    • Do adipokines underlie the association between known risk factors and breast cancer among a cohort of United States women?
    • Gaudet M.M., Falk R.T., Gierach G.L., et al. Do adipokines underlie the association between known risk factors and breast cancer among a cohort of United States women?. Cancer Epidemiol 2010, 34(5):580-586.
    • (2010) Cancer Epidemiol , vol.34 , Issue.5 , pp. 580-586
    • Gaudet, M.M.1    Falk, R.T.2    Gierach, G.L.3
  • 136
    • 54949140363 scopus 로고    scopus 로고
    • Adiponectin mediates an antiproliferative response in human MDA-MB 231 breast cancer cells
    • Dos Santos E., Benaitreau D., Dieudonne M.N., et al. Adiponectin mediates an antiproliferative response in human MDA-MB 231 breast cancer cells. Oncol Rep 2008, 20(4):971-977.
    • (2008) Oncol Rep , vol.20 , Issue.4 , pp. 971-977
    • Dos Santos, E.1    Benaitreau, D.2    Dieudonne, M.N.3
  • 137
    • 77956477076 scopus 로고    scopus 로고
    • Metastasis suppression by adiponectin: LKB1 rises up to the challenge
    • Saxena N.K., Sharma D. Metastasis suppression by adiponectin: LKB1 rises up to the challenge. Cell Adh Migr 2010, 4(3):358-362.
    • (2010) Cell Adh Migr , vol.4 , Issue.3 , pp. 358-362
    • Saxena, N.K.1    Sharma, D.2
  • 138
    • 72549114690 scopus 로고    scopus 로고
    • Involvement of adiponectin and leptin in breast cancer: clinical and in vitro studies
    • Jarde T., Caldefie-Chezet F., Goncalves-Mendes N., et al. Involvement of adiponectin and leptin in breast cancer: clinical and in vitro studies. Endocr Relat Cancer 2009, 16(4):1197-1210.
    • (2009) Endocr Relat Cancer , vol.16 , Issue.4 , pp. 1197-1210
    • Jarde, T.1    Caldefie-Chezet, F.2    Goncalves-Mendes, N.3
  • 139
    • 33947589720 scopus 로고    scopus 로고
    • Antiproliferative effect of adiponectin on MCF7 breast cancer cells: a potential hormonal link between obesity and cancer
    • Arditi J.D., Venihaki M., Karalis K.P., et al. Antiproliferative effect of adiponectin on MCF7 breast cancer cells: a potential hormonal link between obesity and cancer. Horm Metab Res 2007, 39(1):9-13.
    • (2007) Horm Metab Res , vol.39 , Issue.1 , pp. 9-13
    • Arditi, J.D.1    Venihaki, M.2    Karalis, K.P.3
  • 140
    • 68049137624 scopus 로고    scopus 로고
    • LKB1 is required for adiponectin-mediated modulation of AMPK-S6K axis and inhibition of migration and invasion of breast cancer cells
    • Taliaferro-Smith L., Nagalingam A., Zhong D., et al. LKB1 is required for adiponectin-mediated modulation of AMPK-S6K axis and inhibition of migration and invasion of breast cancer cells. Oncogene 2009, 28(29):2621-2633.
    • (2009) Oncogene , vol.28 , Issue.29 , pp. 2621-2633
    • Taliaferro-Smith, L.1    Nagalingam, A.2    Zhong, D.3
  • 141
    • 33749242050 scopus 로고    scopus 로고
    • Adipose tissue production of hepatocyte growth factor contributes to elevated serum HGF in obesity
    • Bell L.N., Ward J.L., Degawa-Yamauchi M., et al. Adipose tissue production of hepatocyte growth factor contributes to elevated serum HGF in obesity. Am J Physiol Endocrinol Metab 2006, 291(4):E843-E848.
    • (2006) Am J Physiol Endocrinol Metab , vol.291 , Issue.4
    • Bell, L.N.1    Ward, J.L.2    Degawa-Yamauchi, M.3
  • 142
    • 0344406152 scopus 로고    scopus 로고
    • Obesity is associated with increased levels of circulating hepatocyte growth factor
    • Rehman J., Considine R.V., Bovenkerk J.E., et al. Obesity is associated with increased levels of circulating hepatocyte growth factor. J Am Coll Cardiol 2003, 41(8):1408-1413.
    • (2003) J Am Coll Cardiol , vol.41 , Issue.8 , pp. 1408-1413
    • Rehman, J.1    Considine, R.V.2    Bovenkerk, J.E.3
  • 143
    • 0028558775 scopus 로고
    • Role of hepatocyte growth factor in breast cancer: a novel mitogenic factor secreted by adipocytes
    • Rahimi N., Saulnier R., Nakamura T., et al. Role of hepatocyte growth factor in breast cancer: a novel mitogenic factor secreted by adipocytes. DNA Cell Biol 1994, 13(12):1189-1197.
    • (1994) DNA Cell Biol , vol.13 , Issue.12 , pp. 1189-1197
    • Rahimi, N.1    Saulnier, R.2    Nakamura, T.3
  • 144
    • 16844362951 scopus 로고    scopus 로고
    • Serum levels of hepatocyte growth factor in patients with breast cancer
    • Sheen-Chen S.M., Liu Y.W., Eng H.L., et al. Serum levels of hepatocyte growth factor in patients with breast cancer. Cancer Epidemiol Biomarkers Prev 2005, 14(3):715-717.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , Issue.3 , pp. 715-717
    • Sheen-Chen, S.M.1    Liu, Y.W.2    Eng, H.L.3
  • 145
    • 0041374029 scopus 로고    scopus 로고
    • Insulin resistance in adipose tissue: direct and indirect effects of tumor necrosis factor-alpha
    • Ruan H., Lodish H.F. Insulin resistance in adipose tissue: direct and indirect effects of tumor necrosis factor-alpha. Cytokine Growth Factor Rev 2003, 14(5):447-455.
    • (2003) Cytokine Growth Factor Rev , vol.14 , Issue.5 , pp. 447-455
    • Ruan, H.1    Lodish, H.F.2
  • 146
    • 33745896155 scopus 로고    scopus 로고
    • Recent advances in the relationship between obesity, inflammation, and insulin resistance
    • Bastard J.P., Maachi M., Lagathu C., et al. Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur Cytokine Netw 2006, 17(1):4-12.
    • (2006) Eur Cytokine Netw , vol.17 , Issue.1 , pp. 4-12
    • Bastard, J.P.1    Maachi, M.2    Lagathu, C.3
  • 147
    • 74849140072 scopus 로고    scopus 로고
    • Soluble factors derived from tumor mammary cell lines induce a stromal mammary adipose reversion in human and mice adipose cells. Possible role of TGF-beta1 and TNF-alpha
    • Guerrero J., Tobar N., Caceres M., et al. Soluble factors derived from tumor mammary cell lines induce a stromal mammary adipose reversion in human and mice adipose cells. Possible role of TGF-beta1 and TNF-alpha. Breast Cancer Res Treat 2010, 119(2):497-508.
    • (2010) Breast Cancer Res Treat , vol.119 , Issue.2 , pp. 497-508
    • Guerrero, J.1    Tobar, N.2    Caceres, M.3
  • 149
    • 0031762908 scopus 로고    scopus 로고
    • Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid
    • Fried S.K., Bunkin D.A., Greenberg A.S. Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid. J Clin Endocrinol Metab 1998, 83(3):847-850.
    • (1998) J Clin Endocrinol Metab , vol.83 , Issue.3 , pp. 847-850
    • Fried, S.K.1    Bunkin, D.A.2    Greenberg, A.S.3
  • 150
    • 0037591513 scopus 로고    scopus 로고
    • Prognostic value of serum levels of interleukin 6 and of serum and plasma levels of vascular endothelial growth factor in hormone-refractory metastatic breast cancer patients
    • Bachelot T., Ray-Coquard I., Menetrier-Caux C., et al. Prognostic value of serum levels of interleukin 6 and of serum and plasma levels of vascular endothelial growth factor in hormone-refractory metastatic breast cancer patients. Br J Cancer 2003, 88(11):1721-1726.
    • (2003) Br J Cancer , vol.88 , Issue.11 , pp. 1721-1726
    • Bachelot, T.1    Ray-Coquard, I.2    Menetrier-Caux, C.3
  • 151
    • 0034696777 scopus 로고    scopus 로고
    • Breast cancer cell line MDA-231 stimulates osteoclastogenesis and bone resorption in human osteoclasts
    • Grano M., Mori G., Minielli V., et al. Breast cancer cell line MDA-231 stimulates osteoclastogenesis and bone resorption in human osteoclasts. Biochem Biophys Res Commun 2000, 270(3):1097-1100.
    • (2000) Biochem Biophys Res Commun , vol.270 , Issue.3 , pp. 1097-1100
    • Grano, M.1    Mori, G.2    Minielli, V.3
  • 152
    • 39449125021 scopus 로고    scopus 로고
    • Modifying effects of IL-6 polymorphisms on body size-associated breast cancer risk
    • Slattery M.L., Curtin K., Sweeney C., et al. Modifying effects of IL-6 polymorphisms on body size-associated breast cancer risk. Obesity (Silver Spring) 2008, 16(2):339-347.
    • (2008) Obesity (Silver Spring) , vol.16 , Issue.2 , pp. 339-347
    • Slattery, M.L.1    Curtin, K.2    Sweeney, C.3
  • 153
    • 56749184290 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor signalling in neoplasia
    • Pollak M. Insulin and insulin-like growth factor signalling in neoplasia. Nat Rev Cancer 2008, 8(12):915-928.
    • (2008) Nat Rev Cancer , vol.8 , Issue.12 , pp. 915-928
    • Pollak, M.1
  • 154
    • 33846846385 scopus 로고    scopus 로고
    • Estrogen receptor regulates insulin-like growth factor-I receptor gene expression in breast tumor cells: involvement of transcription factor Sp1
    • Maor S., Mayer D., Yarden R.I., et al. Estrogen receptor regulates insulin-like growth factor-I receptor gene expression in breast tumor cells: involvement of transcription factor Sp1. J Endocrinol 2006, 191(3):605-612.
    • (2006) J Endocrinol , vol.191 , Issue.3 , pp. 605-612
    • Maor, S.1    Mayer, D.2    Yarden, R.I.3
  • 155
    • 8544284095 scopus 로고    scopus 로고
    • Role of estrogen receptor alpha in modulating IGF-I receptor signaling and function in breast cancer
    • Surmacz E., Bartucci M. Role of estrogen receptor alpha in modulating IGF-I receptor signaling and function in breast cancer. J Exp Clin Cancer Res 2004, 23(3):385-394.
    • (2004) J Exp Clin Cancer Res , vol.23 , Issue.3 , pp. 385-394
    • Surmacz, E.1    Bartucci, M.2
  • 156
    • 0033842834 scopus 로고    scopus 로고
    • Crosstalk between the insulin-like growth factors and estrogens in breast cancer
    • Yee D., Lee A.V. Crosstalk between the insulin-like growth factors and estrogens in breast cancer. J Mammary Gland Biol Neoplasia 2000, 5(1):107-115.
    • (2000) J Mammary Gland Biol Neoplasia , vol.5 , Issue.1 , pp. 107-115
    • Yee, D.1    Lee, A.V.2
  • 157
    • 0035423119 scopus 로고    scopus 로고
    • Re-expression of estrogen receptor alpha in estrogen receptor alpha-negative MCF-7 cells restores both estrogen and insulin-like growth factor-mediated signaling and growth
    • Oesterreich S., Zhang P., Guler R.L., et al. Re-expression of estrogen receptor alpha in estrogen receptor alpha-negative MCF-7 cells restores both estrogen and insulin-like growth factor-mediated signaling and growth. Cancer Res 2001, 61(15):5771-5777.
    • (2001) Cancer Res , vol.61 , Issue.15 , pp. 5771-5777
    • Oesterreich, S.1    Zhang, P.2    Guler, R.L.3
  • 158
    • 76649129882 scopus 로고    scopus 로고
    • Regulation of estrogen receptors alpha and beta in human breast carcinoma by exogenous leptin in nude mouse xenograft model
    • Yu W., Gu J.C., Liu J.Z., et al. Regulation of estrogen receptors alpha and beta in human breast carcinoma by exogenous leptin in nude mouse xenograft model. Chin Med J (Engl) 2010, 123(3):337-343.
    • (2010) Chin Med J (Engl) , vol.123 , Issue.3 , pp. 337-343
    • Yu, W.1    Gu, J.C.2    Liu, J.Z.3
  • 159
    • 77953582276 scopus 로고    scopus 로고
    • Cellular and molecular crosstalk between leptin receptor and estrogen receptor-{alpha} in breast cancer: molecular basis for a novel therapeutic setting
    • Fusco R., Galgani M., Procaccini C., et al. Cellular and molecular crosstalk between leptin receptor and estrogen receptor-{alpha} in breast cancer: molecular basis for a novel therapeutic setting. Endocr Relat Cancer 2010, 17(2):373-382.
    • (2010) Endocr Relat Cancer , vol.17 , Issue.2 , pp. 373-382
    • Fusco, R.1    Galgani, M.2    Procaccini, C.3
  • 160
    • 77953473305 scopus 로고    scopus 로고
    • Expression of estrogen receptor alpha increases leptin-induced STAT3 activity in breast cancer cells
    • Binai N.A., Damert A., Carra G., et al. Expression of estrogen receptor alpha increases leptin-induced STAT3 activity in breast cancer cells. Int J Cancer 2010, 127(1):55-66.
    • (2010) Int J Cancer , vol.127 , Issue.1 , pp. 55-66
    • Binai, N.A.1    Damert, A.2    Carra, G.3
  • 161
    • 0041706381 scopus 로고    scopus 로고
    • Leptin enhances, via AP-1, expression of aromatase in the MCF-7 cell line
    • Catalano S., Marsico S., Giordano C., et al. Leptin enhances, via AP-1, expression of aromatase in the MCF-7 cell line. J Biol Chem 2003, 278(31):28668-28676.
    • (2003) J Biol Chem , vol.278 , Issue.31 , pp. 28668-28676
    • Catalano, S.1    Marsico, S.2    Giordano, C.3
  • 162
    • 75149144405 scopus 로고    scopus 로고
    • The relation of leptin and adiponectin with breast density among premenopausal women
    • Maskarinec G., Woolcott C., Steude J.S., et al. The relation of leptin and adiponectin with breast density among premenopausal women. Eur J Cancer Prev 2010, 19(1):55-60.
    • (2010) Eur J Cancer Prev , vol.19 , Issue.1 , pp. 55-60
    • Maskarinec, G.1    Woolcott, C.2    Steude, J.S.3
  • 163
    • 77954533434 scopus 로고    scopus 로고
    • Correlation of body mass index and leptin with tumor size and stage of disease in hormone-dependent postmenopausal breast cancer: preliminary results and therapeutic implications
    • Maccio A., Madeddu C., Gramignano G., et al. Correlation of body mass index and leptin with tumor size and stage of disease in hormone-dependent postmenopausal breast cancer: preliminary results and therapeutic implications. J Mol Med 2010, 88(7):677-686.
    • (2010) J Mol Med , vol.88 , Issue.7 , pp. 677-686
    • Maccio, A.1    Madeddu, C.2    Gramignano, G.3
  • 164
    • 57149100169 scopus 로고    scopus 로고
    • Bidirectional crosstalk between leptin and insulin-like growth factor-I signaling promotes invasion and migration of breast cancer cells via transactivation of epidermal growth factor receptor
    • Saxena N.K., Taliaferro-Smith L., Knight B.B., et al. Bidirectional crosstalk between leptin and insulin-like growth factor-I signaling promotes invasion and migration of breast cancer cells via transactivation of epidermal growth factor receptor. Cancer Res 2008, 68(23):9712-9722.
    • (2008) Cancer Res , vol.68 , Issue.23 , pp. 9712-9722
    • Saxena, N.K.1    Taliaferro-Smith, L.2    Knight, B.B.3
  • 165
    • 0036130293 scopus 로고    scopus 로고
    • The role of cytokines in regulating estrogen synthesis: implications for the etiology of breast cancer
    • Purohit A., Newman S.P., Reed M.J. The role of cytokines in regulating estrogen synthesis: implications for the etiology of breast cancer. Breast Cancer Res 2002, 4(2):65-69.
    • (2002) Breast Cancer Res , vol.4 , Issue.2 , pp. 65-69
    • Purohit, A.1    Newman, S.P.2    Reed, M.J.3
  • 166
    • 0037823236 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha induces interleukin-6 production via extracellular-regulated kinase 1 activation in breast cancer cells
    • Suarez-Cuervo C., Harris K.W., Kallman L., et al. Tumor necrosis factor-alpha induces interleukin-6 production via extracellular-regulated kinase 1 activation in breast cancer cells. Breast Cancer Res Treat 2003, 80(1):71-78.
    • (2003) Breast Cancer Res Treat , vol.80 , Issue.1 , pp. 71-78
    • Suarez-Cuervo, C.1    Harris, K.W.2    Kallman, L.3
  • 167
    • 80052195187 scopus 로고    scopus 로고
    • World Cancer Research Fund/American Institute for Cancer Research. Food, nutrition, physical activity, and the prevention of cancer: a global perspective. Washington, DC: AICR; 2007.
    • World Cancer Research Fund/American Institute for Cancer Research. Food, nutrition, physical activity, and the prevention of cancer: a global perspective. Washington, DC: AICR; 2007.
  • 168
    • 0344198158 scopus 로고    scopus 로고
    • Lifetime physical activity and breast cancer risk in a multiethnic population: the San Francisco Bay area breast cancer study
    • John E.M., Horn-Ross P.L., Koo J. Lifetime physical activity and breast cancer risk in a multiethnic population: the San Francisco Bay area breast cancer study. Cancer Epidemiol Biomarkers Prev 2003, 12(11 Pt 1):1143-1152.
    • (2003) Cancer Epidemiol Biomarkers Prev , vol.12 , Issue.11 PART 1 , pp. 1143-1152
    • John, E.M.1    Horn-Ross, P.L.2    Koo, J.3
  • 169
    • 0035815185 scopus 로고    scopus 로고
    • Lifetime physical activity and breast cancer risk in the Shanghai Breast Cancer Study
    • Matthews C.E., Shu X.O., Jin F., et al. Lifetime physical activity and breast cancer risk in the Shanghai Breast Cancer Study. Br J Cancer 2001, 84(7):994-1001.
    • (2001) Br J Cancer , vol.84 , Issue.7 , pp. 994-1001
    • Matthews, C.E.1    Shu, X.O.2    Jin, F.3
  • 170
    • 33845481739 scopus 로고    scopus 로고
    • Physical activity and the risk of breast cancer: a case-control study of Japanese women
    • Ueji M., Ueno E., Osei-Hyiaman D., et al. Physical activity and the risk of breast cancer: a case-control study of Japanese women. J Epidemiol 1998, 8(2):116-122.
    • (1998) J Epidemiol , vol.8 , Issue.2 , pp. 116-122
    • Ueji, M.1    Ueno, E.2    Osei-Hyiaman, D.3
  • 171
    • 0037694097 scopus 로고    scopus 로고
    • Physical activity and breast cancer risk among Asian-American women in Los Angeles: a case-control study
    • Yang D., Bernstein L., Wu A.H. Physical activity and breast cancer risk among Asian-American women in Los Angeles: a case-control study. Cancer 2003, 97(10):2565-2575.
    • (2003) Cancer , vol.97 , Issue.10 , pp. 2565-2575
    • Yang, D.1    Bernstein, L.2    Wu, A.H.3
  • 172
    • 0142178215 scopus 로고    scopus 로고
    • Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2
    • King M.C., Marks J.H., Mandell J.B. Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2. Science 2003, 302(5645):643-646.
    • (2003) Science , vol.302 , Issue.5645 , pp. 643-646
    • King, M.C.1    Marks, J.H.2    Mandell, J.B.3
  • 173
    • 33750068287 scopus 로고    scopus 로고
    • Recreational physical activity and survival among young women with breast cancer
    • Abrahamson P.E., Gammon M.D., Lund M.J., et al. Recreational physical activity and survival among young women with breast cancer. Cancer 2006, 107(8):1777-1785.
    • (2006) Cancer , vol.107 , Issue.8 , pp. 1777-1785
    • Abrahamson, P.E.1    Gammon, M.D.2    Lund, M.J.3
  • 174
    • 39449138360 scopus 로고    scopus 로고
    • Physical activity and survival after diagnosis of invasive breast cancer
    • Holick C.N., Newcomb P.A., Trentham-Dietz A., et al. Physical activity and survival after diagnosis of invasive breast cancer. Cancer Epidemiol Biomarkers Prev 2008, 17(2):379-386.
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , Issue.2 , pp. 379-386
    • Holick, C.N.1    Newcomb, P.A.2    Trentham-Dietz, A.3
  • 175
    • 58149230952 scopus 로고    scopus 로고
    • Impact of nutrition and exercise on cancer survival
    • Irwin M.L., Mayne S.T. Impact of nutrition and exercise on cancer survival. Cancer J 2008, 14(6):435-441.
    • (2008) Cancer J , vol.14 , Issue.6 , pp. 435-441
    • Irwin, M.L.1    Mayne, S.T.2
  • 176
    • 58349114267 scopus 로고    scopus 로고
    • Physical activity and risk of recurrence and mortality in breast cancer survivors: findings from the LACE study
    • Sternfeld B., Weltzien E., Quesenberry C.P., et al. Physical activity and risk of recurrence and mortality in breast cancer survivors: findings from the LACE study. Cancer Epidemiol Biomarkers Prev 2009, 18(1):87-95.
    • (2009) Cancer Epidemiol Biomarkers Prev , vol.18 , Issue.1 , pp. 87-95
    • Sternfeld, B.1    Weltzien, E.2    Quesenberry, C.P.3
  • 177
    • 33845894946 scopus 로고    scopus 로고
    • Dietary fat reduction and breast cancer outcome: interim efficacy results from the Women's Intervention Nutrition Study
    • Chlebowski R.T., Blackburn G.L., Thomson C.A., et al. Dietary fat reduction and breast cancer outcome: interim efficacy results from the Women's Intervention Nutrition Study. J Natl Cancer Inst 2006, 98(24):1767-1776.
    • (2006) J Natl Cancer Inst , vol.98 , Issue.24 , pp. 1767-1776
    • Chlebowski, R.T.1    Blackburn, G.L.2    Thomson, C.A.3
  • 178
    • 62749159028 scopus 로고    scopus 로고
    • Implementing a low-fat eating plan in the Women's Intervention Nutrition Study
    • Hoy M.K., Winters B.L., Chlebowski R.T., et al. Implementing a low-fat eating plan in the Women's Intervention Nutrition Study. J Am Diet Assoc 2009, 109(4):688-696.
    • (2009) J Am Diet Assoc , vol.109 , Issue.4 , pp. 688-696
    • Hoy, M.K.1    Winters, B.L.2    Chlebowski, R.T.3
  • 179
    • 34447512756 scopus 로고    scopus 로고
    • Influence of a diet very high in vegetables, fruit, and fiber and low in fat on prognosis following treatment for breast cancer: the Women's Healthy Eating and Living (WHEL) randomized trial
    • Pierce J.P., Natarajan L., Caan B.J., et al. Influence of a diet very high in vegetables, fruit, and fiber and low in fat on prognosis following treatment for breast cancer: the Women's Healthy Eating and Living (WHEL) randomized trial. JAMA 2007, 298(3):289-298.
    • (2007) JAMA , vol.298 , Issue.3 , pp. 289-298
    • Pierce, J.P.1    Natarajan, L.2    Caan, B.J.3
  • 180
    • 77953648429 scopus 로고    scopus 로고
    • Impact of a mixed strength and endurance exercise intervention on levels of adiponectin, high molecular weight adiponectin and leptin in breast cancer survivors
    • Ligibel J.A., Giobbie-Hurder A., Olenczuk D., et al. Impact of a mixed strength and endurance exercise intervention on levels of adiponectin, high molecular weight adiponectin and leptin in breast cancer survivors. Cancer Causes Control 2009, 20(8):1523-1528.
    • (2009) Cancer Causes Control , vol.20 , Issue.8 , pp. 1523-1528
    • Ligibel, J.A.1    Giobbie-Hurder, A.2    Olenczuk, D.3
  • 181
    • 61449154578 scopus 로고    scopus 로고
    • Physical activity interventions for cancer survivors
    • Irwin M.L. Physical activity interventions for cancer survivors. Br J Sports Med 2009, 43(1):32-38.
    • (2009) Br J Sports Med , vol.43 , Issue.1 , pp. 32-38
    • Irwin, M.L.1
  • 182
    • 39749084232 scopus 로고    scopus 로고
    • Impact of a mixed strength and endurance exercise intervention on insulin levels in breast cancer survivors
    • Ligibel J.A., Campbell N., Partridge A., et al. Impact of a mixed strength and endurance exercise intervention on insulin levels in breast cancer survivors. J Clin Oncol 2008, 26(6):907-912.
    • (2008) J Clin Oncol , vol.26 , Issue.6 , pp. 907-912
    • Ligibel, J.A.1    Campbell, N.2    Partridge, A.3
  • 183
    • 33646820924 scopus 로고    scopus 로고
    • Aromatase inhibitors and breast cancer
    • Miller W.R. Aromatase inhibitors and breast cancer. Minerva Endocrinol 2006, 31(1):27-46.
    • (2006) Minerva Endocrinol , vol.31 , Issue.1 , pp. 27-46
    • Miller, W.R.1
  • 184
    • 77949752567 scopus 로고    scopus 로고
    • Intratumoral estrogen disposition in breast cancer
    • Haynes B.P., Straume A.H., Geisler J., et al. Intratumoral estrogen disposition in breast cancer. Clin Cancer Res 2010, 16(6):1790-1801.
    • (2010) Clin Cancer Res , vol.16 , Issue.6 , pp. 1790-1801
    • Haynes, B.P.1    Straume, A.H.2    Geisler, J.3
  • 185
    • 77949908545 scopus 로고    scopus 로고
    • Relationship between plasma estradiol levels and estrogen-responsive gene expression in estrogen receptor-positive breast cancer in postmenopausal women
    • Dunbier A.K., Anderson H., Ghazoui Z., et al. Relationship between plasma estradiol levels and estrogen-responsive gene expression in estrogen receptor-positive breast cancer in postmenopausal women. J Clin Oncol 2010, 28(7):1161-1167.
    • (2010) J Clin Oncol , vol.28 , Issue.7 , pp. 1161-1167
    • Dunbier, A.K.1    Anderson, H.2    Ghazoui, Z.3
  • 186
    • 67649230033 scopus 로고    scopus 로고
    • Aromatase expression and outcomes in the P024 neoadjuvant endocrine therapy trial
    • Ellis M.J., Miller W.R., Tao Y., et al. Aromatase expression and outcomes in the P024 neoadjuvant endocrine therapy trial. Breast Cancer Res Treat 2009, 116(2):371-378.
    • (2009) Breast Cancer Res Treat , vol.116 , Issue.2 , pp. 371-378
    • Ellis, M.J.1    Miller, W.R.2    Tao, Y.3
  • 187
    • 74449085460 scopus 로고    scopus 로고
    • The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival
    • Sachdev D., Zhang X., Matise I., et al. The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival. Oncogene 2010, 29(2):251-262.
    • (2010) Oncogene , vol.29 , Issue.2 , pp. 251-262
    • Sachdev, D.1    Zhang, X.2    Matise, I.3
  • 188
    • 0029821812 scopus 로고    scopus 로고
    • Influence of treatment with tamoxifen and change in tumor burden on the IGF-system in breast cancer patients
    • Helle S.I., Holly J.M., Tally M., et al. Influence of treatment with tamoxifen and change in tumor burden on the IGF-system in breast cancer patients. Int J Cancer 1996, 69(4):335-339.
    • (1996) Int J Cancer , vol.69 , Issue.4 , pp. 335-339
    • Helle, S.I.1    Holly, J.M.2    Tally, M.3
  • 189
    • 0026706686 scopus 로고
    • Tamoxifen reduces serum insulin-like growth factor I (IGF-I)
    • Pollak M.N., Huynh H.T., Lefebvre S.P. Tamoxifen reduces serum insulin-like growth factor I (IGF-I). Breast Cancer Res Treat 1992, 22(1):91-100.
    • (1992) Breast Cancer Res Treat , vol.22 , Issue.1 , pp. 91-100
    • Pollak, M.N.1    Huynh, H.T.2    Lefebvre, S.P.3
  • 190
    • 56749118600 scopus 로고    scopus 로고
    • The aromatase inhibitor letrozole and inhibitors of insulin-like growth factor I receptor synergistically induce apoptosis in in vitro models of estrogen-dependent breast cancer
    • Lisztwan J., Pornon A., Chen B., et al. The aromatase inhibitor letrozole and inhibitors of insulin-like growth factor I receptor synergistically induce apoptosis in in vitro models of estrogen-dependent breast cancer. Breast Cancer Res 2008, 10(4):R56.
    • (2008) Breast Cancer Res , vol.10 , Issue.4
    • Lisztwan, J.1    Pornon, A.2    Chen, B.3
  • 191
    • 13344270279 scopus 로고    scopus 로고
    • Diabetes mellitus and breast cancer
    • Wolf I., Sadetzki S., Catane R., et al. Diabetes mellitus and breast cancer. Lancet Oncol 2005, 6(2):103-111.
    • (2005) Lancet Oncol , vol.6 , Issue.2 , pp. 103-111
    • Wolf, I.1    Sadetzki, S.2    Catane, R.3
  • 192
    • 20444494440 scopus 로고    scopus 로고
    • Therapy insight: influence of type 2 diabetes on the development, treatment and outcomes of cancer
    • Richardson L.C., Pollack L.A. Therapy insight: influence of type 2 diabetes on the development, treatment and outcomes of cancer. Nat Clin Pract Oncol 2005, 2(1):48-53.
    • (2005) Nat Clin Pract Oncol , vol.2 , Issue.1 , pp. 48-53
    • Richardson, L.C.1    Pollack, L.A.2
  • 193
    • 79151478459 scopus 로고    scopus 로고
    • Evaluation of metformin in early breast cancer: a modification of the traditional paradigm for clinical testing of anti-cancer agents
    • Goodwin P.J., Stambolic V., Lemieux J., et al. Evaluation of metformin in early breast cancer: a modification of the traditional paradigm for clinical testing of anti-cancer agents. Breast Cancer Res Treat 2011, 126(1):215-220.
    • (2011) Breast Cancer Res Treat , vol.126 , Issue.1 , pp. 215-220
    • Goodwin, P.J.1    Stambolic, V.2    Lemieux, J.3
  • 194
    • 77955923866 scopus 로고    scopus 로고
    • Metformin: taking away the candy for cancer?
    • Jalving M., Gietema J.A., Lefrandt J.D., et al. Metformin: taking away the candy for cancer?. Eur J Cancer 2010, 46(13):2369-2380.
    • (2010) Eur J Cancer , vol.46 , Issue.13 , pp. 2369-2380
    • Jalving, M.1    Gietema, J.A.2    Lefrandt, J.D.3
  • 195
    • 78649369121 scopus 로고    scopus 로고
    • Peptide-based leptin receptor antagonists for cancer treatment and appetite regulation
    • Otvos L., Kovalszky I., Scolaro L., et al. Peptide-based leptin receptor antagonists for cancer treatment and appetite regulation. Peptide Science 2011, 96:117-125.
    • (2011) Peptide Science , vol.96 , pp. 117-125
    • Otvos, L.1    Kovalszky, I.2    Scolaro, L.3
  • 196
    • 70349741579 scopus 로고    scopus 로고
    • Leptin-signaling inhibition results in efficient anti-tumor activity in estrogen receptor positive or negative breast cancer
    • Rene Gonzalez R., Watters A., Xu Y., et al. Leptin-signaling inhibition results in efficient anti-tumor activity in estrogen receptor positive or negative breast cancer. Breast Cancer Res 2009, 11(3):R36.
    • (2009) Breast Cancer Res , vol.11 , Issue.3
    • Rene Gonzalez, R.1    Watters, A.2    Xu, Y.3
  • 197
    • 2442662761 scopus 로고    scopus 로고
    • Association of frequency and duration of aspirin use and hormone receptor status with breast cancer risk
    • Terry M.B., Gammon M.D., Zhang F.F., et al. Association of frequency and duration of aspirin use and hormone receptor status with breast cancer risk. JAMA 2004, 291(20):2433-2440.
    • (2004) JAMA , vol.291 , Issue.20 , pp. 2433-2440
    • Terry, M.B.1    Gammon, M.D.2    Zhang, F.F.3
  • 198
    • 23444434370 scopus 로고    scopus 로고
    • Use of nonsteroidal antiinflammatory drugs and risk of breast cancer: the Case-Control Surveillance Study revisited
    • Zhang Y., Coogan P.F., Palmer J.R., et al. Use of nonsteroidal antiinflammatory drugs and risk of breast cancer: the Case-Control Surveillance Study revisited. Am J Epidemiol 2005, 162(2):165-170.
    • (2005) Am J Epidemiol , vol.162 , Issue.2 , pp. 165-170
    • Zhang, Y.1    Coogan, P.F.2    Palmer, J.R.3
  • 199
    • 4143114828 scopus 로고    scopus 로고
    • Risk of breast cancer among users of aspirin and other anti-inflammatory drugs
    • Garcia Rodriguez L.A., Gonzalez-Perez A. Risk of breast cancer among users of aspirin and other anti-inflammatory drugs. Br J Cancer 2004, 91(3):525-529.
    • (2004) Br J Cancer , vol.91 , Issue.3 , pp. 525-529
    • Garcia Rodriguez, L.A.1    Gonzalez-Perez, A.2
  • 200
    • 2442651752 scopus 로고    scopus 로고
    • Aspirin and breast cancer prevention: the estrogen connection
    • DuBois R.N. Aspirin and breast cancer prevention: the estrogen connection. JAMA 2004, 291(20):2488-2489.
    • (2004) JAMA , vol.291 , Issue.20 , pp. 2488-2489
    • DuBois, R.N.1
  • 201
    • 33645097043 scopus 로고    scopus 로고
    • Energy balance adiposity and breast cancer-energy restriction strategies for breast cancer prevention
    • Harvie M., Howell A. Energy balance adiposity and breast cancer-energy restriction strategies for breast cancer prevention. Obes Rev 2006, 7(1):33-47.
    • (2006) Obes Rev , vol.7 , Issue.1 , pp. 33-47
    • Harvie, M.1    Howell, A.2


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