Lifestyle determinants of serum insulin-like growth-factor-I (IGF-I), C-peptide and hormone binding protein levels in British women

Cancer Causes and Control

Volumn 14, Issue 1, 2003, Pages 65-74

  Allen, Naomi E ^a   Appleby, Paul N ^a   Kaaks, Rudolf ^b   Rinaldi, Sabina ^b   Davey, Gwyneth K ^a   Key, Timothy J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

Author keywords

IGF binding proteins; IGF I; Lifestyle determinants; Women

Indexed keywords

C PEPTIDE; HORMONE BINDING PROTEIN; SEX HORMONE BINDING PROTEIN; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN BINDING PROTEIN 2; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

ADULT; AGED; ARTICLE; BLOOD LEVEL; BODY MASS; CANCER RISK; EXERCISE; FEMALE; HUMAN; IMMUNOASSAY; LEAN BODY WEIGHT; LEISURE; LIFESTYLE; OBESITY; PHYSICAL ACTIVITY; PRIORITY JOURNAL; REPRODUCTION; SMOKING; UNITED KINGDOM; WORK;

ADULT; AGE FACTORS; BODY MASS INDEX; C-PEPTIDE; FEMALE; GREAT BRITAIN; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; INSULIN-LIKE GROWTH FACTOR I; LIFE STYLE; MIDDLE AGED; MOTOR ACTIVITY; NEOPLASMS; RISK; SEX HORMONE-BINDING GLOBULIN;

EID: 0037305130     PISSN: 09575243     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022518321634     Document Type: Article

References (58)

1. Pollak M (2000) Insulin-like growth factor physiology and cancer risk. Eur J Cancer 36: 1224-1228.
2. Hankinson SE, Willett WC, Colditz GA, et al. (1998) Circulating concentrations of insulin-like growth factor-I and risk of breast cancer. Lancet 351: 1393-1396.
3. Toniolo P, Bruning PF, Akhmedkhanov A, et al. (2000) Serum insulin-like growth factor-I and breast cancer. Int J Cancer 88: 828-832.
4. Giovannucci E, Pollak MN, Platz EA, et al. (2000) A prospective study of plasma insulin-like growth factor-1 and binding protein-3 and risk of colorectal neoplasia in women. Cancer Epidemiol Biomarkers Prev 9: 345-349.
5. Kaaks R, Toniolo P, Akhmedkhanov A, et al. (2000) Serum C-peptide, insulin-like growth factor (IGF)-I, IGF-binding proteins, and colorectal cancer risk in women. J Natl Cancer Inst 92: 1592-1600.
6. Holly JM, Hughes SC (1994) Measuring insulin-like growth factors: why, where and how? J Endocrinol 140: 165-169.
7. Jones JI, Clemmons DR (1995) Insulin-like growth factors and their binding proteins: biological actions. Endocrinol Rev 16: 3-34.
8. Kelley KM, Oh Y, Gargosky SE, et al. (1996) Insulin-like growth factor-binding proteins (IGFBPs) and their regulatory dynamics. Int J Biochem Cell Biol 28: 619-637.
9. Allen NE, Appleby PN, Davey GK, Key TJ (2000) Hormones and diet: low insulin-like growth factor-1 but normal bioavailable androgens in vegan men. Br J Cancer 83: 95-97.
10. Allen NE, Appleby PN, Davey GK, Kaaks R, Rinaldi S (2002) The effects of diet on serum insulin-like growth factor-I and its main binding proteins in 292 women meat-eaters, vegetarians and vegans. Cancer Epidemiol Biomarkers Prev (In press).
11. Thissen JP, Ketelslegers JM, Underwood LE (1994) Nutritional regulation of the insulin-like growth factors. Endocrinol Rev 15: 80-101.
12. Landin-Wilhelmsen K, Wilhelmsen L, Lappas G, et al. (1994) Serum insulin-like growth factor I in a random population sample of men and women: relation to age, sex, smoking habits, coffee consumption and physical activity, blood pressure and concentrations of plasma lipids, fibrinogen, parathyroid hormone and osteocalcin. Clin Endocrinol 41: 351-357.
13. Goodman-Gruen D, Barrett-Connor E (1997) Epidemiology of insulin-like growth factor-I in elderly men and women. The Rancho Bernardo Study. Am J Epidemiol 145: 970-976.
14. Janssen JA, Stolk RP, Pols HA, Grobbee DE, de Jong FH, Lamberts SW (1998) Serum free IGF-1, total IGF-I, IGFBP-1 and IGFBP-3 levels in an elderly population: relation to age and sex steroid levels. Clin Endocrinol 48: 471-478.
15. Kaklamani VG, Linos A, Kaklamani E, Markaki I, Mantzoros C (1999) Age, sex, and smoking are predictors of circulating insulin-like growth factor 1 and insulin-like growth factor-binding protein 3. J Clin Oncol 17: 813-817.
16. Lukanova A, Toniolo P, Akhmedkhanov A, et al. (2001) A cross-sectional study of IGF-I determinants in women. Eur J Cancer Prev 10: 443-452.
17. Chang S, Wu X, Yu H, Spitz MR (2002) Plasma concentrations of insulin-like growth factors among healthy men and postmenopausal women: associations with body composition, lifestyle and reproductive factors. Cancer Epidemiol Biomarkers Prev 11: 758-766.
18. Riboli E, Kaaks R (1997) The EPIC Project: rationale and study design. European Prospective Investigation into Cancer and Nutrition. Int J Epidemiol 26 (Suppl. 1): S6-14.
19. Pols MA, Peeters PH, Ocke MC, Slimani N, Bueno-de-Mesquita HB, Collette HJ (1997) Estimation of reproducibility and relative validity of the questions included in the EPIC Physical Activity Questionnaire. Int J Epidemiol 26 (Suppl. 1): S181-S189.
20. Statacorp (2001) Stata statistical software, Release 7.0. College Station, TX: Stata Corporation.
21. Copeland KC, Colletti RB, Devlin JT, McAuliffe TL (1990) The relationship between insulin-like growth factor-I, adiposity, and aging. Metabolism 39: 584-587.
22. Juul A, Main K, Blum WF, Lindholm J, Ranke MB, Skakkebaek NE (1994) The ratio between serum levels of insulin-like growth factor (IGF)-I and the IGF binding proteins (IGFBP-1, 2 and 3) decreases with age in healthy adults and is increased in acromegalic patients. Clin Endocrinol 41: 85-93.
23. Benbassat CA, Maki KC, Unterman TG (1997) Circulating levels of insulin-like growth factor (IGF) binding protein-1 and -3 in aging men: relationships to insulin, glucose, IGF, and dehydroepiandrosterone sulfate levels and anthropometric measures. J Clin Endocrinol Metab 82: 1484-1491.
24. Corpas E, Harman SM, Blackman MR (1993) Human growth hormone and human aging. Endocrinol Rev 14: 20-39.
25. Lieberman SA, Mitchell AM, Marcus R, Hintz RL, Hoffman AR (1994) The insulin-like growth factor I generation test: resistance to growth hormone with aging and estrogen replacement therapy. Horm Metab Res 26: 229-233.
26. Rutanen EM, Karkkainen T, Stenman UH, Yki-Jarvinen H (1993) Aging is associated with decreased suppression of insulin-like growth factor binding protein-1 by insulin. J Clin Endocrinol Metab 77: 1152-1155.
27. Nystrom FH, Ohman PK, Ekman BA, Osterlund MK, Karlberg BE, Arnqvist HJ (1997) Population-based reference values for IGF-I and IGF-binding protein-1: relations with metabolic and anthropometric variables. Eur J Endocrinol 136: 165-172.
28. Kassem M, Brixen K, Mosekilde L, Blum WF, Flyvbjerg A (1998) Effects of growth hormone treatment on serum levels of insulin-like growth factors (IGFs) and IGF binding proteins 1-4 in postmenopausal women. Clin Endocrinol 49: 747-756.
29. Voskuil DW, Bas Bueno de Mesquita H, Kaaks R, et al. (2001) Determinants of circulating insulin-like growth factor (IGF-I) and IGF binding proteins 1-3 in premenopausal women: physical activity and anthropometry (Netherlands). Cancer Causes Control 12: 951-958.
30. Schoen RE, Schragin J, Weissfeld JL, et al. (2002) Lack of association between adipose tissue distribution and IGF-1 and IGFBP-3 in men and women. Cancer Epidemiol Biomarkers Prev 11: 581-586.
31. Argente J, Caballo N, Barrios V, et al. (1997) Multiple endocrine abnormalities of the growth hormone and insulin-like growth factor axis in patients with anorexia nervosa: effect of short- and long-term weight recuperation. J Clin Endocrinol Metab 82: 2084-2092.
32. Counts DR, Gwirtsman H, Carlsson LM, Lesem M, Cutler GBJ (1992) The effect of anorexia nervosa and refeeding on growth hormone-binding protein, the insulin-like growth factors (IGFs), and the IGF-binding proteins. J Clin Endocrinol Metab 75: 762-767.
33. Gianotti L, Broglio F, Ramunni J, et al. (1998) The activity of GH/IGF-I axis in anorexia nervosa and in obesity: a comparison with normal subjects and patients with hypopituitarism or critical illness. Eat Weight Disord 3: 64-70.
34. Maccario M, Gauna C, Procopio M, et al. (1999) Assessment of GH/IGF-I axis in obesity by evaluation of IGF-I levels and the GH response to GHRH+ arginine test. J Endocrinol Invest 22: 424-429.
35. Kaaks R, Lukanova A (2001) Energy balance and cancer: the role of insulin and insulin-like growth factor-I. Proc Nutr Soc 60: 91-106.
36. Maccario M, Tassone F, Grottoli S, Rossetto R, Gauna C, Ghigo E (2002) Neuroendocrine and metabolic determinants of the adaptation of GH/IGF-I axis to obesity. Ann Endocrinol 63: 140-144.
37. Bernardi F, Petraglia F, Seppala M, et al. (1998) Somatotropic axis and body weight in pre-menopausal and post-menopausal women: evidence for a neuroendocrine derangement, in absence of changes of insulin-like growth factor binding protein concentrations. Human Reprod 13: 279-284.
38. Pasquali R, Casimirri F, Plate L, Capelli M (1990) Characterization of obese women with reduced sex hormone-binding globulin concentrations. Horm Metab Res 22: 303-306.
39. Verkasalo PK, Thomas HV, Appleby PN, Davey GK, Key TJ (2001) Circulating levels of sex hormones and their relation to risk factors for breast cancer: a cross-sectional study in 1092 pre- and postmenopausal women (United Kingdom). Cancer Causes Control 12: 47-59.
40. Frystyk J, Skjaerbaek C, Vestbo E, Fisker S, Orskov H (1999) Circulating levels of free insulin-like growth factors in obese subjects: the impact of type 2 diabetes. Diabetes Metab Res Rev 15: 314-322.
41. Conover CA, Lee PD (1990) Insulin regulation of insulin-like growth factor-binding protein production in cultured HepG2 cells. J Clin Endocrinol Metab 70: 1062-1067.
42. Boni-Schnetzler M, Schmid C, Mary JL, et al. (1990) Insulin regulates the expression of the insulin-like growth factor binding protein 2 mRNA in rat hepatocytes. Mol Endocrinol 4: 1320-1326.
43. Plymate SR, Matej LA, Jones RE, Friedl KE (1988) Inhibition of sex hormone-binding globulin production in the human hepatoma (Hep G2) cell line by insulin and prolactin. J Clin Endocrinol Metab 67: 460-464.
44. Ma J, Pollak MN, Giovannucci E, et al. (1999) Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. J Natl Cancer Inst 91: 620-625.
45. Signorello LB, Kuper J, Lagiou P, et al. (2000) Lifestyle factors and insulin-like growth factor-I levels among elderly men. Eur J Cancer Prev 9: 173-178.
46. Blake EJ, Adel T, Santoro N (1997) Relationships between insulin-like growth hormone factor-I and estradiol in reproductive aging. Fertil Steril 67: 697-701.
47. Jernström H, Barrett-Connor E (1999) Obesity, weight change, fasting insulin, proinsulin, C-peptide, and insulin-like growth factor-1 levels in women with and without breast cancer: the Rancho Bernardo Study. J Womens Health Gend Based Med 8: 1265-1272.
48. Weissberger AJ, Ho KK, Lazarus L (1991) Contrasting effects of oral and transdermal routes of estrogen replacement therapy on 24-hour growth hormone (GH) secretion, insulin-like growth factor I, and GH-binding protein in postmenopausal women. J Clin Endocrinol Metab 72: 374-381.
49. Jernström H, Olsson H (1994) Suppression of plasma insulin-like growth factor-1 levels in healthy, nulliparous, young women using low dose oral contraceptives. Gynecol Obstet Invest 38: 261-265.
50. Poehlman ET, Copeland KC (1990) Influence of physical activity on insulin-like growth factor-I in healthy younger and older men. J Clin Endocrinol Metab 71: 1468-1473.
51. Bonnefoy M, Kostka T, Patricot MC, Berthouze SE, Mathian B, Lacour JR (1998) Physical activity and dehydroepiandrosterone sulphate, insulin-like growth factor I and testosterone in healthy active elderly people. Age Ageing 27: 745-751.
52. Jahreis G, Hesse V, Schmidt HE, Scheibe J (1989) Effect of endurance exercise on somatomedin-C/insulin-like growth factor I concentration in male and female runners. Exp Clin Endocrinol 94: 89-96.
53. Jahreis G, Kauf E, Frohner G, Schmidt HE (1991) Influence of intensive exercise on insulin-like growth factor I, thyroid and steroid hormones in female gymnasts. Growth Reg 1: 95-99.
54. Eliakim A, Brasel JA, Mohan S, Barstow TJ, Berman N, Cooper DM (1996) Physical fitness, endurance training, and the growth hormone-insulin-like growth factor I system in adolescent females. J Clin Endocrinol Metab 81: 3986-3992.
55. Mayer-Davis EJ, D'Agostino RJ, Karter AJ, et al. (1998) Intensity and amount of physical activity in relation to insulin sensitivity: the Insulin Resistance Atherosclerosis Study. JAMA 279: 669-674.
56. Irwin ML, Mayer-Davis EJ, Addy CL, et al. (2000) Moderate-intensity physical activity and fasting insulin levels in women: the Cross-Cultural Activity Participation Study. Diabetes Care 23: 449-454.
57. Kahn BB, Flier JS (2000) Obesity and insulin resistance. J Clin Invest 106: 473-481. Koivisto VA, Yki-Jarvinen H, DeFronzo RA (1986) Physical training and insulin sensitivity. Diabetes Metab Rev 1: 445-481.
58. Devlin JT (1992) Effects of exercise on insulin sensitivity in humans. Diabetes Care 15: 1690-1693.