Heparin oligosaccharides that pass the blood-brain barrier inhibit β- amyloid precursor protein secretion and heparin binding to β-amyloid peptide

Journal of Neurochemistry

Volumn 70, Issue 2, 1998, Pages 736-744

  Leveugle, Béatrice ^a,b   Ding, Wanhong ^a   Laurence, Fenart ^c   Dehouck, Marie Pierre ^c   Scanameo, Andrew ^a   Cecchelli, Roméo ^c   Fillit, Howard ^a  

^a MOUNT SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF ALBERTA   (Canada)

^c INSERM   (France)

Author keywords

Alzheimer's disease; Glycosaminoglycans; Heparan sulfate; Proteoglycans; Therapy

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; LOW MOLECULAR WEIGHT HEPARIN; OLIGOSACCHARIDE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BLOOD BRAIN BARRIER; DEGENERATIVE DISEASE; ENDOTHELIUM CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0031938180     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70020736.x     Document Type: Article

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