Insig-1 "brakes" lipogenesis in adipocytes and inhibits differentiation of preadipocytes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 16, 2003, Pages 9476-9481

  Li, Jinping ^a   Takaishi, Kiyosumi ^a,c   Cook, William ^a   McCorkle, Sara Kay ^a   Unger, Roger H ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b VA NORTH TEXAS HEALTH CARE SYSTEM   (United States)

^c DAIICHI SANKYO CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; GENE PRODUCT; GLUCOSE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN INSIG 1; PROTEIN INSIG 2; STEROL REGULATORY ELEMENT BINDING PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DIET RESTRICTION; DIETARY INTAKE; DOWN REGULATION; ENDOPLASMIC RETICULUM; GENE EXPRESSION; GENETIC TRANSFECTION; LIPID DIET; LIPOGENESIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION;

3T3 CELLS; ADIPOCYTES; ANIMALS; AZO COMPOUNDS; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BLOTTING, NORTHERN; CARBOHYDRATE METABOLISM; CELL DIFFERENTIATION; CELL DIVISION; COLORING AGENTS; DIET; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; DOWN-REGULATION; GLUCOSE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; OBESITY; PLASMIDS; PROTEIN BINDING; PROTEINS; RADIOIMMUNOASSAY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSFECTION; UP-REGULATION;

ANIMALIA; EUKARYOTA;

EID: 0041923552     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.1133426100     Document Type: Article

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