Defective nuclear translocation of stress-activated signaling in senescent diploid human fibroblasts: A possible explanation for aging-associated apoptosis resistance

Apoptosis

Volumn 16, Issue 8, 2011, Pages 795-807

  Kim, Sung Young ^a   Ryu, Sung Jin ^a   Kang, Hyun Tae ^a   Choi, Hae Ri ^a   Park, Sang Chul ^a,b  

^a Seoul National University College of Medicine   (South Korea)

^b Gachon University   (South Korea)

Author keywords

Apoptosis; Fibroblast; Mitogen activated protein kinases; Nucleocytoplasmic transport; Senescence

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; AGGLUTININ; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BCL 2; STAUROSPORINE; SYNAPTOPHYSIN; THAPSIGARGIN;

APOPTOSIS; ARTICLE; CELL AGING; CELL MIGRATION; CONTROLLED STUDY; CYTOPLASM; DIPLOIDY; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

APOPTOSIS; CELL AGING; CELL CULTURE TECHNIQUES; CELL SURVIVAL; CELLS, CULTURED; CHILD, PRESCHOOL; DIPLOIDY; FIBROBLASTS; FLAVONOIDS; FORESKIN; HUMANS; HYDROGEN PEROXIDE; IMIDAZOLES; INTERPHASE; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRIDINES; STAUROSPORINE; STRESS, PHYSIOLOGICAL; WHEAT GERM AGGLUTININS;

TRITICUM AESTIVUM;

EID: 80051548324     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-011-0612-2     Document Type: Article

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