Gelsolin for Senescence-Associated Resistance to Apoptosis

Annals of the New York Academy of Sciences

Volumn 1010, Issue , 2003, Pages 493-495

  Ahn, Jeong Soo ^a   Jang, I K Soon ^a   Rhim, J Heon ^a   Kim, Kyungtae ^a   Yeo, Eui J U ^b   Park, Sang Chul ^a  

^a Seoul National University   (South Korea)

^b Gachon University College of Medicine   (South Korea)

Author keywords

Apoptotic resistance; Gelsolin; Senescence

Indexed keywords

ACTIN; ANTISENSE OLIGONUCLEOTIDE; GELSOLIN; MENADIONE; MESSENGER RNA;

APOPTOSIS; CELL AGING; CELL NUCLEUS; CONFERENCE PAPER; DIPLOIDY; DOWN REGULATION; FIBROBLAST; HUMAN; MITOCHONDRION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SENESCENCE; STRESS FIBER;

EID: 1342284272     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1299.090     Document Type: Conference Paper

References (5)

1. WANG, E. 1995. Senescent human fibroblasts resist programmed cell death, and failure to suppress bel 2 is involved. Cancer Res. 55: 2284-2292.
2. YIN, H.L. & T.P. STOSSEL. 1979. Control of cytoplasmic actin gel-sol transformation by gelsolin, a calcium-dependent regulatory protein. Nature 281: 583-586.
3. SUN, H.Q., M. YAMAMOTO, M. MEJILLANO & H.L. YIN. 1999. Gelsolin, a multifunctional actin regulatory protein. J. Biol. Chem. 274: 33179-33182.
4. KUSANO, H., S. SHIMIZU, R.C. KOYA, et al. 2000. Human gelsolin prevents apoptosis by inhibiting apoptotic mitochondrial changes via closing VDAC. Oncogene 19: 4807-4814.
5. TSUJIMOTO, Y. & S. SHIMIZU. 2000. Bcl-2 family. FEBS Lett. 466: 6-10.