메뉴 건너뛰기




Volumn 10, Issue 4, 2000, Pages 415-422

Reduction of UV-induced cell death in the human senescent fibroblasts

Author keywords

Cell Death; H2O2; p21Waf1; Senescence; Stress activated Protein Kinase

Indexed keywords

CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; DNA FRAGMENT; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE;

EID: 0034738934     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (52)

References (45)
  • 1
    • 0030477686 scopus 로고    scopus 로고
    • Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
    • Alcorta, D. A., Xiong, Y., Phelps, D., Hannon, G., Beach, D., and Barrett, J. C. (1996) Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts. Proc. Natl. Acad. Sci. USA 93, 13742-13747.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13742-13747
    • Alcorta, D.A.1    Xiong, Y.2    Phelps, D.3    Hannon, G.4    Beach, D.5    Barrett, J.C.6
  • 3
    • 0027431143 scopus 로고
    • Serine/threonine protein kinases and calcium-dependent protease in senescent IMR-90 fibroblasts
    • Blumenthal, E., Miller, J., Anita, C. K., Stein, G. H., and Malkinson, A. M. (1993) Serine/threonine protein kinases and calcium-dependent protease in senescent IMR-90 fibroblasts. Mech. Aging Dev. 72, 13-24.
    • (1993) Mech. Aging Dev. , vol.72 , pp. 13-24
    • Blumenthal, E.1    Miller, J.2    Anita, C.K.3    Stein, G.H.4    Malkinson, A.M.5
  • 4
    • 0020513440 scopus 로고
    • Calcium-regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum free serial culture
    • Boyce, S. T. and Ham, R. G. (1993) Calcium-regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum free serial culture. J. Invest. Dermatol. 81, 33S-40S.
    • (1993) J. Invest. Dermatol. , vol.81
    • Boyce, S.T.1    Ham, R.G.2
  • 5
    • 0030609861 scopus 로고    scopus 로고
    • Bypass of senescence after disruption of p21cip1/waf1 gene in normal diploid human fibroblasts
    • Brown, J. P., Wei, W., and Sedivy, J. M. (1997) Bypass of senescence after disruption of p21cip1/waf1 gene in normal diploid human fibroblasts. Science 277, 831-834.
    • (1997) Science , vol.277 , pp. 831-834
    • Brown, J.P.1    Wei, W.2    Sedivy, J.M.3
  • 6
    • 0028301074 scopus 로고
    • Decline of protein kinase C activation in response to growth stimulation during senescence of IMR-90 human diploid fibroblasts
    • Chang, Z. F. and Huang, D. Y. (1994) Decline of protein kinase C activation in response to growth stimulation during senescence of IMR-90 human diploid fibroblasts. Biochem. Biophys. Res. Commun. 15, 16-27.
    • (1994) Biochem. Biophys. Res. Commun. , vol.15 , pp. 16-27
    • Chang, Z.F.1    Huang, D.Y.2
  • 9
    • 0029753773 scopus 로고    scopus 로고
    • The role of c-jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation
    • Chen, Y. R., Wang, X., Templeton, D., Davis, R. J., and Tan, T. H. (1996) The role of c-jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. J. Biol. Chem. 271, 31929-31936.
    • (1996) J. Biol. Chem. , vol.271 , pp. 31929-31936
    • Chen, Y.R.1    Wang, X.2    Templeton, D.3    Davis, R.J.4    Tan, T.H.5
  • 11
    • 0028329953 scopus 로고
    • JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
    • Derijard, B., Hibi, M., Wu, I. H., Barrett, T., Su, B., Deng, T., Karin, M., and Davis, R. J. (1994) JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76, 1025-1037.
    • (1994) Cell , vol.76 , pp. 1025-1037
    • Derijard, B.1    Hibi, M.2    Wu, I.H.3    Barrett, T.4    Su, B.5    Deng, T.6    Karin, M.7    Davis, R.J.8
  • 13
    • 0032563286 scopus 로고    scopus 로고
    • Cip/Waf1 by caspases is an early event during DNA damage-induced apoptosis
    • Cip/Waf1 by caspases is an early event during DNA damage-induced apoptosis. J. Biol. Chem. 273, 19207-19212.
    • (1998) J. Biol. Chem. , vol.273 , pp. 19207-19212
    • Gervais, J.L.M.1    Seth, P.2    Zhang, H.3
  • 14
    • 0031935827 scopus 로고    scopus 로고
    • Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies
    • Gire, V. and Wynford-Thomas, D. (1998) Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies. Mol. Cell. Biol. 18, 1611-1621.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 1611-1621
    • Gire, V.1    Wynford-Thomas, D.2
  • 15
    • 0344623063 scopus 로고    scopus 로고
    • Age-associated changes in human epidermal cell renewal
    • Grove, G. and Kligman, A. M. (1998) Age-associated changes in human epidermal cell renewal. J. Gerontol. 38, 59-63.
    • (1998) J. Gerontol. , vol.38 , pp. 59-63
    • Grove, G.1    Kligman, A.M.2
  • 17
    • 0027423418 scopus 로고
    • Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain
    • Hibi, M., Lin, A., Smeal, T., Minden, A., and Karin, M. (1993) Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev. 7, 2135-2148.
    • (1993) Genes Dev. , vol.7 , pp. 2135-2148
    • Hibi, M.1    Lin, A.2    Smeal, T.3    Minden, A.4    Karin, M.5
  • 19
    • 0030959304 scopus 로고    scopus 로고
    • Bcl-2 phosphorylation required for anti-apoptosis function
    • Ito, T., Deng, X., Carr, B., and May, W. S. (1997) Bcl-2 phosphorylation required for anti-apoptosis function. J. Biol. Chem. 272, 11671-11673.
    • (1997) J. Biol. Chem. , vol.272 , pp. 11671-11673
    • Ito, T.1    Deng, X.2    Carr, B.3    May, W.S.4
  • 21
    • 0022551801 scopus 로고
    • Increased level of cAMP-dependent protein kinase in aging human lung fibroblasts
    • Liu, A. Y., Chang, Z. E, and Chen, K. J. (1986) Increased level of cAMP-dependent protein kinase in aging human lung fibroblasts. J. Cell. Physiol. 128, 149-154.
    • (1986) J. Cell. Physiol. , vol.128 , pp. 149-154
    • Liu, A.Y.1    Chang, Z.E.2    Chen, K.J.3
  • 22
    • 0029199452 scopus 로고
    • The end of the (cell) line: Methods for the study of apoptosis in vitro
    • Schwartz, L. M. and Osborne, B. A. (eds.), Academic Press, NY
    • MaGahon, A. J., Martin, S. J., Bissonnette, R. P., Mahboubi, A., Shi, Y., Mogil, R. J., Nishioka, W. K., and Green, D. R. (1995) The end of the (cell) line: methods for the study of apoptosis in vitro; in Methods in Cell Biology, Schwartz, L. M. and Osborne, B. A. (eds.), Vol. 46, pp. 153-181, Academic Press, NY.
    • (1995) Methods in Cell Biology , vol.46 , pp. 153-181
    • MaGahon, A.J.1    Martin, S.J.2    Bissonnette, R.P.3    Mahboubi, A.4    Shi, Y.5    Mogil, R.J.6    Nishioka, W.K.7    Green, D.R.8
  • 23
    • 0027938445 scopus 로고
    • Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases
    • Minden, A., Lin, A., Smeal, T., Derijard, B., Cobb, M., Davis, R. J., and Karin, M. (1994) c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases. Mol. Cell. Biol. 14, 6683-6688.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 6683-6688
    • Minden, A.1    Lin, A.2    Smeal, T.3    Derijard, B.4    Cobb, M.5    Davis, R.J.6    Karin, M.7
  • 24
    • 0028342664 scopus 로고
    • Cloning of senescent cell derived inhibitors of DNA synthesis using an expression screen
    • Noda, A., Ning, Y., Venable, S. F., Pereira-Smith, O. M., and Smith, J. R. (1994) Cloning of senescent cell derived inhibitors of DNA synthesis using an expression screen. Exp. Cell. Res. 211, 90-98.
    • (1994) Exp. Cell. Res. , vol.211 , pp. 90-98
    • Noda, A.1    Ning, Y.2    Venable, S.F.3    Pereira-Smith, O.M.4    Smith, J.R.5
  • 25
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai, Z. N., Milliman, C. L., and Korsmeyer, S. J. (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74, 609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 26
    • 0030857126 scopus 로고    scopus 로고
    • Activation of c-Jun N-terminal kinase antagonizes an anti-apoptotic action of bcl-2
    • Park, J., Kim, I., Oh, Y. J., Lee, K. W., Han, P. L., and Choi, E. J. (1997) Activation of c-Jun N-terminal kinase antagonizes an anti-apoptotic action of bcl-2. J. Biol. Chem. 272, 16725-16728.
    • (1997) J. Biol. Chem. , vol.272 , pp. 16725-16728
    • Park, J.1    Kim, I.2    Oh, Y.J.3    Lee, K.W.4    Han, P.L.5    Choi, E.J.6
  • 28
    • 0032544739 scopus 로고    scopus 로고
    • Grb2 interaction with MEK-Kinase 1 is involved in regulation of Jun-kinase activities in response to epidermal growth factor
    • Pomerance, M., Multon, M. C., Parker, F., Venot, C., Blondeau, J. P., Tacque, B., and Schweighoffer, F. (1998) Grb2 interaction with MEK-Kinase 1 is involved in regulation of Jun-kinase activities in response to epidermal growth factor. J. Biol. Chem. 273, 24301-24304.
    • (1998) J. Biol. Chem. , vol.273 , pp. 24301-24304
    • Pomerance, M.1    Multon, M.C.2    Parker, F.3    Venot, C.4    Blondeau, J.P.5    Tacque, B.6    Schweighoffer, F.7
  • 29
    • 0028935270 scopus 로고
    • Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
    • Raingeaud, J., Gupta, S., Rogers, J. S., Dickens, M., Han, J., Ulevitch, R. J., and Davis, R. J. (1995) Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J. Biol. Chem. 270, 7420-7426.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7420-7426
    • Raingeaud, J.1    Gupta, S.2    Rogers, J.S.3    Dickens, M.4    Han, J.5    Ulevitch, R.J.6    Davis, R.J.7
  • 30
    • 0029860936 scopus 로고    scopus 로고
    • Ultraviolet light and osmotic stress: Activation of the JNK cascade through multiple growth factor and cytokine receptors
    • Rosette, C. and Karin, M. (1996) Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors. Science 274, 1194-1197.
    • (1996) Science , vol.274 , pp. 1194-1197
    • Rosette, C.1    Karin, M.2
  • 31
    • 0032566717 scopus 로고    scopus 로고
    • A functional role for mitochondrial protien kinase Cα in bcl2 phosphorylation and suppression of apoptosis
    • Ruvolo, P. P., Deng, X., Carr, B. N., and May, W. S. (1998) A functional role for mitochondrial protien kinase Cα in bcl2 phosphorylation and suppression of apoptosis. J. Biol. Chem. 273, 25436-25442.
    • (1998) J. Biol. Chem. , vol.273 , pp. 25436-25442
    • Ruvolo, P.P.1    Deng, X.2    Carr, B.N.3    May, W.S.4
  • 33
    • 0025751550 scopus 로고
    • Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
    • Sentman, C. L., Shutter, J. R., Hockenbery, D., Kanagawa, O., and Korsmeyer, S. J. (1991) Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell 67, 879-888.
    • (1991) Cell , vol.67 , pp. 879-888
    • Sentman, C.L.1    Shutter, J.R.2    Hockenbery, D.3    Kanagawa, O.4    Korsmeyer, S.J.5
  • 34
    • 0029957019 scopus 로고    scopus 로고
    • A non-enzymatic p21 protein inhibitor of stress-activated protein kinases
    • Shim, J., Lee, H., Park, J., Kim, H., and Choi, E. (1996) A non-enzymatic p21 protein inhibitor of stress-activated protein kinases. Nature 381, 804-807.
    • (1996) Nature , vol.381 , pp. 804-807
    • Shim, J.1    Lee, H.2    Park, J.3    Kim, H.4    Choi, E.5
  • 35
    • 0030038104 scopus 로고    scopus 로고
    • Replicative senescence implications for in vivo aging and tumor suppression
    • Smith, J. R. and Pereira-Smith, O. M. (1996) Replicative senescence implications for in vivo aging and tumor suppression. Science 273, 63-67.
    • (1996) Science , vol.273 , pp. 63-67
    • Smith, J.R.1    Pereira-Smith, O.M.2
  • 36
    • 0031813790 scopus 로고    scopus 로고
    • Involvement of microtubules in the regulation of bcl-2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase
    • Srivastava, R. K., Strivastava, A. R., Korsmeyer, S. J., Nesterova, M., Cho-Chung, Y. S., and Longo, D. L. (1998) Involvement of microtubules in the regulation of bcl-2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase. Mol. Cell. Biol. 18, 3509-3517.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3509-3517
    • Srivastava, R.K.1    Strivastava, A.R.2    Korsmeyer, S.J.3    Nesterova, M.4    Cho-Chung, Y.S.5    Longo, D.L.6
  • 37
    • 0033013980 scopus 로고    scopus 로고
    • Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanism of senescence and differentiation in human fibroblasts
    • Stein, G. H., Drullinger, L. F., Soulard, A., and Dulic, V. (1999) Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanism of senescence and differentiation in human fibroblasts. Mol. Cell. Biol. 19, 2109-2117.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2109-2117
    • Stein, G.H.1    Drullinger, L.F.2    Soulard, A.3    Dulic, V.4
  • 38
    • 0031570536 scopus 로고    scopus 로고
    • Bcl-2 prevents apoptosis induced by perforin and granzyme B, but not that mediated by whole cytotoxic lymphocytes
    • Sutton, V., Vaux, D. L., and Trapani, J. A. (1997) Bcl-2 prevents apoptosis induced by perforin and granzyme B, but not that mediated by whole cytotoxic lymphocytes. J. Immunol. 158, 5783-5790.
    • (1997) J. Immunol. , vol.158 , pp. 5783-5790
    • Sutton, V.1    Vaux, D.L.2    Trapani, J.A.3
  • 39
    • 0028109996 scopus 로고
    • Identification of a defect in the phospholipase D/diacylglycerol pathway in cellular senescence
    • Venable, M. E., Blobe, G. C., and Obeid, L. M. (1994) Identification of a defect in the phospholipase D/diacylglycerol pathway in cellular senescence. J. Biol. Chem. 269, 26040-26044.
    • (1994) J. Biol. Chem. , vol.269 , pp. 26040-26044
    • Venable, M.E.1    Blobe, G.C.2    Obeid, L.M.3
  • 41
    • 0030011128 scopus 로고    scopus 로고
    • Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21
    • Waldman, T., Lengauer, C., Kinzler, K. W., and Vogelstein, B. (1996) Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature 381, 713-716.
    • (1996) Nature , vol.381 , pp. 713-716
    • Waldman, T.1    Lengauer, C.2    Kinzler, K.W.3    Vogelstein, B.4
  • 42
    • 0029023626 scopus 로고
    • Senescent human fibroblasts resist programmed cell death and failure to suppress bcl2 is involved
    • Wang, E. (1995) Senescent human fibroblasts resist programmed cell death and failure to suppress bcl2 is involved. Cancer Res. 55, 2284-2292.
    • (1995) Cancer Res. , vol.55 , pp. 2284-2292
    • Wang, E.1
  • 43
    • 0029996726 scopus 로고    scopus 로고
    • Resistance to apoptosis conferred by cdk inhibitors during myocyte differentiation
    • Wang, J. and Walsh, K. (1996) Resistance to apoptosis conferred by cdk inhibitors during myocyte differentiation. Science 273, 359-361.
    • (1996) Science , vol.273 , pp. 359-361
    • Wang, J.1    Walsh, K.2
  • 44
    • 0029944622 scopus 로고    scopus 로고
    • Differential CDK-inhibitor gene expression in aging human diploid fibroblasts
    • Wong, H. and Riabowol, K. (1996) Differential CDK-inhibitor gene expression in aging human diploid fibroblasts. Exp. Gerontol. 31, 311-325.
    • (1996) Exp. Gerontol. , vol.31 , pp. 311-325
    • Wong, H.1    Riabowol, K.2
  • 45
    • 0029899181 scopus 로고    scopus 로고
    • Molecular thanatopsis: A discourse on the bcl-2 family and cell death
    • Yang, E. and Korsmeyer, S. J. (1996) Molecular thanatopsis: a discourse on the bcl-2 family and cell death. Blood 88, 386-401.
    • (1996) Blood , vol.88 , pp. 386-401
    • Yang, E.1    Korsmeyer, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.