EGFR-dependent ERK activation triggers hydrogen peroxide-induced apoptosis in OK renal epithelial cells

Archives of Toxicology

Volumn 80, Issue 6, 2006, Pages 337-346

  Lee, Ju Suk ^a   Kim, Su Yung ^a   Kwon, Chae Hwa ^a   Kim, Yong Keun ^a  

^a Pusan National University School of Medicine   (South Korea)

Author keywords

Apoptosis; Caspase activation; Epidermal growth factor receptor; ERK activation; Hydrogen peroxide; Mitochondrial hyperpolarization; Opossum kidney cells

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; CATALASE; EPIDERMAL GROWTH FACTOR RECEPTOR; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; UO 126;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ENZYME ACTIVATION; EPITHELIUM CELL; FLOW CYTOMETRY; KIDNEY DISEASE; KIDNEY EPITHELIUM; MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; OPOSSUM; PRIORITY JOURNAL; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BUTADIENES; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; HYDROGEN PEROXIDE; KIDNEY TUBULES, PROXIMAL; MAP KINASE KINASE 1; MEMBRANE POTENTIALS; MITOCHONDRIAL MEMBRANES; NITRILES; OPOSSUMS; OXIDANTS; PYRIMIDINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; TRANSFECTION; TYRPHOSTINS;

DIDELPHIDAE;

EID: 33646564393     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-005-0052-2     Document Type: Article

References (48)

1. 2 cytotoxicity in mouse renal proximal tubule cells. Kidney Int 65:1231-1239
2. Baek SM, Kwon CH, Kim JH, Woo JS, Jung JS, Kim YK (2003) Differential roles of hydrogen peroxide and hydroxyl radical in cisplatin-induced cell death in renal proximal tubular epithelial cells. J Lab Clin Med 142:178-186
3. Banki K, Hutter E, Gonchoroff NJ, Perl A (1999) Elevation of mitochondrial transmembrane potential and reactive oxygen intermediate levels are early events and occur independently from activation of caspases in Fas signaling. J Immunol 162:1466-1479
4. Baud L, Ardaillou R (1986) Reactive oxygen species: production and role in the kidney. Am J Physiol 251:F765-F776
5. Bhat NR, Zhang P (1999) Hydrogen peroxide activation of multiple mitogen-activated protein kinases in an oligodendrocyte cell line: role of extracellular signal-regulated kinase in hydrogen peroxide-induced cell death. J Neurochem 72:112-119
6. 2-induced apoptotic cell death via ERK activation. J Neurochem 76:910-918
7. Chen M, Jahnukainen T, Bao W, Dare E, Ceccatelli S, Celsi G (2003) Uropathogenic Escherichia coli toxins induce caspase-independent apoptosis in renal proximal tubular cells via ERK signaling. Am J Nephrol 23:140
8. Cobb MH (1999) MAP kinase pathways. Prog Biophys Mol Biol 71:479-500
9. L translocation in renal tubular epithelial cells in vitro protects distal cells from oxidative stress. Kidney Int 59:1779-1788
10. Davis RJ (2000) Signal transduction by the JNK group of MAP kinases. Cell 103:239-252
11. di Mari JF, Davis R, Safirstein RL (1999) MAPK activation determines renal epithelial cell survival during oxidative injury. Am J Physiol 277:F195-F203
12. Diamond JR, Bonventre JV, Karnovsky MJ (1986) A role for oxygen free radicals in aminonucleoside nephrosis. Kidney Int 29:478-483
13. Dong J, Ramachandiran S, Tikoo K, Jia Z, Lau SS, Monks TJ (2004) EGFR-independent activation of p38 MAPK and EGFR-dependent activation of ERK1/2 are required for ROS-induced renal cell death. Am J Physiol 287:F1049-F1058
14. Dudley DT, Pang L, Decker SJ, Bridges AJ, Saltiel AR (1995) A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc Natl Acad Sci USA 92:7686-7689
15. Favata MF, Horiuchi KY, Manos EJ, Daulerio AJ, Stradley DA, Feeser WS, Van Dyk DE, Pitts WJ, Earl RA, Hobbs F, Copeland RA, Magolda RL, Scherle PA, Trzaskos JM (1998) Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 273:18623-18632
16. Green DR, Reed JC (1998) Mitochondria and apoptosis. Science 281:1309-1312
17. Gschwind A, Zwick E, Prenzel N, Leserer M, Ullrich A (2001) Cell communication networks: epidermal growth factor receptor transactivation as the paradigm for inter receptor signal transmission. Oncogene 20:1594-1600
18. 2. Role in cell survival following oxidant injury. J Biol Chem 271:4138-4142
19. Ishikawa Y, Kitamura M (2000) Anti-apoptotic effect of quercetin: intervention in the JNK- and ERK-mediated apoptotic pathways. Kidney Int 58:1078-1087
20. Kim YK, Kim HJ, Kwon CH, Kim JH, Woo JS, Jung Js, Kim JM (2005) Role of ERK activation in cisplatin-induced apoptosis in OK renal epithelial cells. J Appl Toxicol 25:374-382
21. Kroemer G, Dallaporta B, Resche-Rigon M (1998) The mitochondrial death/life regulator in apoptosis and necrosis. Annu Rev Physiol 60:619-642
22. Lemasters JJ, Nieminen AL, Qian T, Trost LC, Herman B (1997) The mitochondrial permeability transition in toxic, hypoxic and reperfusion injury. Mol Cell Biochem 174:159-165
23. Leonard SS, Harris GK, Shi X (2004) Metal-induced oxidative stress and signal transduction. Free Radic Biol Med 37:1921-1942
24. Lieberthal W, Levine JS (1996) Mechanisms of apoptosis and its potential role in renal tubular epithelial cell injury. Am J Physiol 271:F477-F488
25. Martindale JL, Holbrook NJ (2002) Cellular response to oxidative stress: signaling for suicide and survival. J Cell Physiol 192:1-15
26. Meves A, Stock SN, Beyerle A, Pittelkow MR, Peus D (2001) H(2)O(2) mediates oxidative stress-induced epidermal growth factor receptor phosphorylation. Toxicol Lett 122:205-214
27. Nowak G (2002) PKC-a and ERK1/2 mediate mitochondrial dysfunction, decreases in active Na+ transport, and cisplatin-induced apoptosis in renal cells. J Biol Chem 277:43377-43388
28. Paller MS, Hoidal JR, Ferris TF (1984) Oxygen free radicals in ischemic acute renal failure in the rat. J Clin Invest 74:1156-1164
29. Pastorino JG, Snyder JW, Serroni A, Hoek JB, Farber JL (1993) Cyclosporin and carnitine prevent the anoxic death of cultured hepatocytes by inhibiting the mitochondrial permeability transition. J Biol Chem 268:13791-13798
30. 2 is required for UVB-induced EGF receptor and downstream signaling pathway activation. Free Radic Biol Med 27:1197-1202
31. Piret JP, Arnould T, Fuks B, Chatelain P, Remade J, Michiels C (2004) Mitochondria permeability transition-dependent tert-butyl hydroperoxide-induced apoptosis in hepatoma HepG2 cells. Biochem Pharmacol 67:611-620
32. Poppe M, Reimertz C, Dussmann H, Krohn AJ, Luetjens CM, Bockelmann D, Nieminen AL, Kogel D, Prehn JH (2001) Dissipation of potassium and proton gradients inhibits mitochondrial hyperpolarization and cytochrome c release during neural apoptosis. J Neurosci 21:4551-4563
33. Prenzel N, Fischer OM, Streit S, Hart S, Ullrich A (2001) The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification. Endocr Relat Cancer 8:11-31
34. Puskas F, Gergely P Jr, Banki K, Perl A (2000) Stimulation of the pentose phosphate pathway and glutathione levels by dehydroascorbate, the oxidized form of vitamin C. Faseb J 14:1352-1361
35. Ramachandiran S, Huang O, Dong J, Lau SS, Monks TJ (2002) Mitogen-activated protein kinases contribute to reactive oxygen species-induced cell death in renal proximal tubular epithelial cells. Chem Res Toxicol 15:1635-1642
36. Rana A, Sathyanarayana P, Lieberthal W (2001) Role of apoptosis of renal tubular cells in acute renal failure: therapeutic implications. Apoptosis 6:83-102
37. Rehan A, Johnson KJ, Wiggins RC, Kunkel RG, Ward PA (1984) Evidence for the role of oxygen radicals in acute nephrotoxic nephritis. Lab Invest 51:396-403
38. Sachsenmaier C, Radler-Pohl A, Zinck R, Nordheim A, Herrlich P, Rahmsdorf HJ (1994) Involvement of growth factor receptors in the mammalian UVC response. Cell 78:963-972
39. Sato K, Sato A, Aoto M, Fukami Y (1995) c-Src phosphorylates epidermal growth factor receptor on tyrosine 845. Biochem Biophys Res Commun 215:1078-1087
40. Takeda M, Shirato I, Kobayashi M, Endou H (1999) Hydrogen peroxide induces necrosis, apoptosis, oncosis and apoptotic oncosis of mouse terminal proximal straight tubule cells. Nephron 81:234-238
41. Tatton WG, Olanow CW (1999) Apoptosis in neurodegenerative diseases: the role of mitochondria. Biochim Biophys Acta 1410:195-213
42. Tian W, Zhang Z, Cohen DM (2000) MAPK signaling and the kidney. Am J Physiol Renal Physiol 279:F593-F604
43. Ueda N, Kaushal GP, Shah SV (2000) Apoptotic mechanisms in acute renal failure. Am J Med 108:403-415
44. Walker PD, Shah SV (1988) Evidence suggesting a role for hydroxyl radical in gentamicin-induced acute renal failure in rats. J Clin Invest 81:334-341
45. Wang X, Martindale JL, Liu Y, Holbrook NJ (1998) The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival. Biochem J 333:291-300
46. Waterhouse NJ, Goldstein JC, von Ahsen O, Schuler M, Newmeyer DD, Green DR (2001) Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process. J Cell Biol 153:319-328
47. Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME (1995) Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270:1326-1331
48. 2-induced transactivation of EGF receptor requires Src and mediates ERK1/2, but not Akt, activation in renal cells. Am J Physiol Renal Physiol 286:F858-F865