The first nucleotide binding domain of the sulfonylurea receptor 2A contains regulatory elements and is folded and functions as an independent module

Biochemistry

Volumn 50, Issue 31, 2011, Pages 6655-6666

  De Araujo, Elvin D ^a   Ikeda, Lynn K ^a   Tzvetkova, Svetlana ^a   Kanelis, Voula ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ATP BINDING; ATP HYDROLYSIS; ATP-BINDING CASSETTE; BIOPHYSICAL STUDIES; C-TERMINAL EXTENSIONS; DISORDERED REGIONS; DOMAIN BOUNDARY; GENERAL METHOD; HETEROLOGOUS EXPRESSION; LIMITED INFORMATION; NUCLEOTIDE-BINDING DOMAIN; PRECISE DEFINITION; REGULATORY ELEMENTS; REGULATORY SUBUNITS; SCREENING DATA; SEQUENCE ALIGNMENTS; STRUCTURE-BASED; SUBDOMAIN; SULFONYLUREA RECEPTORS;

ADENOSINETRIPHOSPHATE; ALIGNMENT; BINDING SITES; HYDROLYSIS; POTASSIUM; PROTEINS; SOLUBILITY;

NUCLEOTIDES;

ABC TRANSPORTER; SULFONYLUREA RECEPTOR; SULFONYLUREA RECEPTOR 2A; SUMO PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; CARDIOVASCULAR DISEASE; CELL MIGRATION; CONTROLLED STUDY; GENE MUTATION; HYDROLYSIS; NONHUMAN; NUCLEOTIDE BINDING DOMAIN; PREDICTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PURIFICATION; PROTEIN STRUCTURE; SOLUBILITY;

AMINO ACID SEQUENCE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CRYSTALLOGRAPHY, X-RAY; DNA-BINDING PROTEINS; KATP CHANNELS; MOLECULAR SEQUENCE DATA; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, DRUG; REGULATORY ELEMENTS, TRANSCRIPTIONAL; RESPONSE ELEMENTS; SOLUBILITY;

EUKARYOTA;

EID: 79961045929     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi200434d     Document Type: Article

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