메뉴 건너뛰기




Volumn 140, Issue 1-2, 2011, Pages 130-139

Transcriptional profiling of immune genes in bovine monocyte-derived macrophages exposed to bacterial antigens

Author keywords

Cattle; Lipopolysaccharide; Macrophage; Monocyte; Purified protein derivative; Real time quantitative reverse transcription PCR; Toll like receptor

Indexed keywords

BACTERIAL ANTIGEN; CHEMOKINE; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MYELOID DIFFERENTIATION FACTOR 88; RANTES; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 6; TUBERCULIN;

EID: 79961009047     PISSN: 01652427     EISSN: 18732534     Source Type: Journal    
DOI: 10.1016/j.vetimm.2010.12.002     Document Type: Article
Times cited : (37)

References (63)
  • 1
    • 0028970464 scopus 로고
    • Interferon-alpha primes macrophages for lipopolysaccharide-induced apoptosis
    • Adler B., Adler H., Jungi T.W., Peterhans E. Interferon-alpha primes macrophages for lipopolysaccharide-induced apoptosis. Biochem. Biophys. Res. Commun. 1995, 215:921-927.
    • (1995) Biochem. Biophys. Res. Commun. , vol.215 , pp. 921-927
    • Adler, B.1    Adler, H.2    Jungi, T.W.3    Peterhans, E.4
  • 3
    • 33744920115 scopus 로고    scopus 로고
    • Production of interferon-gamma by myeloid cells-fact or fancy?
    • Bogdan C., Schleicher U. Production of interferon-gamma by myeloid cells-fact or fancy?. Trends Immunol. 2006, 27:282-290.
    • (2006) Trends Immunol. , vol.27 , pp. 282-290
    • Bogdan, C.1    Schleicher, U.2
  • 6
    • 34249707214 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: activation and regulation during toll-like receptor signaling
    • Carmody R.J., Chen Y.H. Nuclear factor-kappaB: activation and regulation during toll-like receptor signaling. Cell Mol. Immunol. 2007, 4:31-41.
    • (2007) Cell Mol. Immunol. , vol.4 , pp. 31-41
    • Carmody, R.J.1    Chen, Y.H.2
  • 8
    • 33745184046 scopus 로고    scopus 로고
    • Ante mortem diagnosis of tuberculosis in cattle: a review of the tuberculin tests, gamma-interferon assay and other ancillary diagnostic techniques
    • de la Rua-Domenech R., Goodchild A.T., Vordermeier H.M., Hewinson R.G., Christiansen K.H., Clifton-Hadley R.S. Ante mortem diagnosis of tuberculosis in cattle: a review of the tuberculin tests, gamma-interferon assay and other ancillary diagnostic techniques. Res. Vet. Sci. 2006, 81:190-210.
    • (2006) Res. Vet. Sci. , vol.81 , pp. 190-210
    • de la Rua-Domenech, R.1    Goodchild, A.T.2    Vordermeier, H.M.3    Hewinson, R.G.4    Christiansen, K.H.5    Clifton-Hadley, R.S.6
  • 9
    • 36448984661 scopus 로고    scopus 로고
    • The toll-like receptor-4 (TLR-4) pathway and its possible role in the pathogenesis of Escherichia coli mastitis in dairy cattle
    • De Schepper S., De Ketelaere A., Bannerman D.D., Paape M.J., Peelman L., Burvenich C. The toll-like receptor-4 (TLR-4) pathway and its possible role in the pathogenesis of Escherichia coli mastitis in dairy cattle. Vet. Res. 2008, 39:5.
    • (2008) Vet. Res. , vol.39 , pp. 5
    • De Schepper, S.1    De Ketelaere, A.2    Bannerman, D.D.3    Paape, M.J.4    Peelman, L.5    Burvenich, C.6
  • 10
    • 30544438071 scopus 로고    scopus 로고
    • IFN-gamma enhances bovine macrophage responsiveness to Mycobacterium bovis: impact on bacterial replication, cytokine release and macrophage apoptosis
    • Denis M., Wedlock D.N., Buddle B.M. IFN-gamma enhances bovine macrophage responsiveness to Mycobacterium bovis: impact on bacterial replication, cytokine release and macrophage apoptosis. Immunol. Cell Biol. 2005, 83:643-650.
    • (2005) Immunol. Cell Biol. , vol.83 , pp. 643-650
    • Denis, M.1    Wedlock, D.N.2    Buddle, B.M.3
  • 11
    • 27644531470 scopus 로고    scopus 로고
    • Identification and characterization of an immunogenic 22kDa exported protein of Mycobacterium avium subspecies paratuberculosis
    • Dupont C., Thompson K., Heuer C., Gicquel B., Murray A. Identification and characterization of an immunogenic 22kDa exported protein of Mycobacterium avium subspecies paratuberculosis. J. Med. Microbiol. 2005, 54:1083-1092.
    • (2005) J. Med. Microbiol. , vol.54 , pp. 1083-1092
    • Dupont, C.1    Thompson, K.2    Heuer, C.3    Gicquel, B.4    Murray, A.5
  • 13
    • 60949083191 scopus 로고    scopus 로고
    • A current perspective on availability of tools, resources and networks for veterinary immunology
    • Entrican G., Lunney J.K., Rutten V.P., Baldwin C.L. A current perspective on availability of tools, resources and networks for veterinary immunology. Vet. Immunol. Immunopathol. 2009, 128:24-29.
    • (2009) Vet. Immunol. Immunopathol. , vol.128 , pp. 24-29
    • Entrican, G.1    Lunney, J.K.2    Rutten, V.P.3    Baldwin, C.L.4
  • 14
    • 0034646695 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide activates NF-kappaB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells. Differential expression of TLR-4 and TLR-2 in endothelial cells
    • Faure E., Equils O., Sieling P.A., Thomas L., Zhang F.X., Kirschning C.J., Polentarutti N., Muzio M., Arditi M. Bacterial lipopolysaccharide activates NF-kappaB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells. Differential expression of TLR-4 and TLR-2 in endothelial cells. J. Biol. Chem. 2000, 275:11058-11063.
    • (2000) J. Biol. Chem. , vol.275 , pp. 11058-11063
    • Faure, E.1    Equils, O.2    Sieling, P.A.3    Thomas, L.4    Zhang, F.X.5    Kirschning, C.J.6    Polentarutti, N.7    Muzio, M.8    Arditi, M.9
  • 15
    • 0035253370 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-kappa B activation
    • Faure E., Thomas L., Xu H., Medvedev A., Equils O., Arditi M. Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-kappa B activation. J. Immunol. 2001, 166:2018-2024.
    • (2001) J. Immunol. , vol.166 , pp. 2018-2024
    • Faure, E.1    Thomas, L.2    Xu, H.3    Medvedev, A.4    Equils, O.5    Arditi, M.6
  • 16
    • 39149138139 scopus 로고    scopus 로고
    • Possible role for Toll-like receptors in interaction of Fasciola hepatica excretory/secretory products with bovine macrophages
    • Flynn R.J., Mulcahy G. Possible role for Toll-like receptors in interaction of Fasciola hepatica excretory/secretory products with bovine macrophages. Infect. Immun. 2008, 76:678-684.
    • (2008) Infect. Immun. , vol.76 , pp. 678-684
    • Flynn, R.J.1    Mulcahy, G.2
  • 18
    • 33947667498 scopus 로고    scopus 로고
    • What is the role of Toll-like receptors in bacterial infections?
    • Gerold G., Zychlinsky A., de Diego J.L. What is the role of Toll-like receptors in bacterial infections?. Semin. Immunol. 2007, 19:41-47.
    • (2007) Semin. Immunol. , vol.19 , pp. 41-47
    • Gerold, G.1    Zychlinsky, A.2    de Diego, J.L.3
  • 19
    • 8444220047 scopus 로고    scopus 로고
    • The effect of the tuberculin test and the consequences of a delay in blood culture on the sensitivity of a gamma-interferon assay for the detection of Mycobacterium bovis infection in cattle
    • Gormley E., Doyle M.B., McGill K., Costello E., Good M., Collins J.D. The effect of the tuberculin test and the consequences of a delay in blood culture on the sensitivity of a gamma-interferon assay for the detection of Mycobacterium bovis infection in cattle. Vet. Immunol. Immunopathol. 2004, 102:413-420.
    • (2004) Vet. Immunol. Immunopathol. , vol.102 , pp. 413-420
    • Gormley, E.1    Doyle, M.B.2    McGill, K.3    Costello, E.4    Good, M.5    Collins, J.D.6
  • 22
    • 33644980250 scopus 로고    scopus 로고
    • Novel role and regulation of the interleukin-1 receptor associated kinase (IRAK) family proteins
    • Huang Y.S., Misior A., Li L.W. Novel role and regulation of the interleukin-1 receptor associated kinase (IRAK) family proteins. Cell. Mol. Immunol. 2005, 2:36-39.
    • (2005) Cell. Mol. Immunol. , vol.2 , pp. 36-39
    • Huang, Y.S.1    Misior, A.2    Li, L.W.3
  • 23
    • 39049130811 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide induces increased expression of toll-like receptor (TLR) 4 and downstream TLR signaling molecules in bovine mammary epithelial cells
    • Ibeagha-Awemu E.M., Lee J.W., Ibeagha A.E., Bannerman D.D., Paape M.J., Zhao X. Bacterial lipopolysaccharide induces increased expression of toll-like receptor (TLR) 4 and downstream TLR signaling molecules in bovine mammary epithelial cells. Vet. Res. 2008, 39:11.
    • (2008) Vet. Res. , vol.39 , pp. 11
    • Ibeagha-Awemu, E.M.1    Lee, J.W.2    Ibeagha, A.E.3    Bannerman, D.D.4    Paape, M.J.5    Zhao, X.6
  • 24
    • 0027742263 scopus 로고
    • Reactivities of 20 anti-human monoclonal antibodies with leucocytes from ten different animal species
    • Jacobsen C.N., Aasted B., Broe M.K., Petersen J.L. Reactivities of 20 anti-human monoclonal antibodies with leucocytes from ten different animal species. Vet. Immunol. Immunopathol. 1993, 39:461-466.
    • (1993) Vet. Immunol. Immunopathol. , vol.39 , pp. 461-466
    • Jacobsen, C.N.1    Aasted, B.2    Broe, M.K.3    Petersen, J.L.4
  • 25
    • 33749428998 scopus 로고    scopus 로고
    • Development and validation of a bovine macrophage specific cDNA microarray
    • Jensen K., Talbot R., Paxton E., Waddington D., Glass E.J. Development and validation of a bovine macrophage specific cDNA microarray. BMC Genomics 2006, 7:224.
    • (2006) BMC Genomics , vol.7 , pp. 224
    • Jensen, K.1    Talbot, R.2    Paxton, E.3    Waddington, D.4    Glass, E.J.5
  • 26
    • 34047262879 scopus 로고    scopus 로고
    • Intracellular signalling cascades regulating innate immune responses to Mycobacteria: branching out from Toll-like receptors
    • Jo E.K., Yang C.S., Choi C.H., Harding C.V. Intracellular signalling cascades regulating innate immune responses to Mycobacteria: branching out from Toll-like receptors. Cell. Microbiol. 2007, 9:1087-1098.
    • (2007) Cell. Microbiol. , vol.9 , pp. 1087-1098
    • Jo, E.K.1    Yang, C.S.2    Choi, C.H.3    Harding, C.V.4
  • 27
    • 0028215641 scopus 로고
    • Change in sensitivity to lipopolysaccharide during the differentiation of human monocytes to macrophages in vitro
    • Jungi T.W., Miserez R., Brcic M., Pfister H. Change in sensitivity to lipopolysaccharide during the differentiation of human monocytes to macrophages in vitro. Experientia 1994, 50:110-114.
    • (1994) Experientia , vol.50 , pp. 110-114
    • Jungi, T.W.1    Miserez, R.2    Brcic, M.3    Pfister, H.4
  • 28
    • 0033166381 scopus 로고    scopus 로고
    • Differential induction of NO synthesis by gram-positive and gram-negative bacteria and their components in bovine monocyte-derived macrophages
    • Jungi T.W., Valentin-Weigand P., Brcic M. Differential induction of NO synthesis by gram-positive and gram-negative bacteria and their components in bovine monocyte-derived macrophages. Microb. Pathog. 1999, 27:43-53.
    • (1999) Microb. Pathog. , vol.27 , pp. 43-53
    • Jungi, T.W.1    Valentin-Weigand, P.2    Brcic, M.3
  • 29
    • 20544474210 scopus 로고    scopus 로고
    • Pathogen recognition with Toll-like receptors
    • Kawai T., Akira S. Pathogen recognition with Toll-like receptors. Curr. Opin. Immunol. 2005, 17:338-344.
    • (2005) Curr. Opin. Immunol. , vol.17 , pp. 338-344
    • Kawai, T.1    Akira, S.2
  • 30
    • 51349158231 scopus 로고    scopus 로고
    • Signalling adaptors used by Toll-like receptors: an update
    • Kenny E.F., O'Neill L.A. Signalling adaptors used by Toll-like receptors: an update. Cytokine 2008, 43:342-349.
    • (2008) Cytokine , vol.43 , pp. 342-349
    • Kenny, E.F.1    O'Neill, L.A.2
  • 31
    • 47649118596 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis heat shock protein 60 modulates immune response to PPD by manipulating the surface expression of TLR2 on macrophages
    • Khan N., Alam K., Mande S.C., Valluri V.L., Hasnain S.E., Mukhopadhyay S. Mycobacterium tuberculosis heat shock protein 60 modulates immune response to PPD by manipulating the surface expression of TLR2 on macrophages. Cell. Microbiol. 2008, 10:1711-1722.
    • (2008) Cell. Microbiol. , vol.10 , pp. 1711-1722
    • Khan, N.1    Alam, K.2    Mande, S.C.3    Valluri, V.L.4    Hasnain, S.E.5    Mukhopadhyay, S.6
  • 32
    • 74449093648 scopus 로고    scopus 로고
    • Susceptibility to paratuberculosis infection in cattle is associated with single nucleotide polymorphisms in Toll-like receptor 2 which modulate immune responses against Mycobacterium avium subspecies paratuberculosis
    • Koets A., Santema W., Mertens H., Oostenrijk D., Keestra M., Overdijk M., Labouriau R., Franken P., Frijters A., Nielen M., Rutten V. Susceptibility to paratuberculosis infection in cattle is associated with single nucleotide polymorphisms in Toll-like receptor 2 which modulate immune responses against Mycobacterium avium subspecies paratuberculosis. Prev. Vet. Med. 2010, 93:305-315.
    • (2010) Prev. Vet. Med. , vol.93 , pp. 305-315
    • Koets, A.1    Santema, W.2    Mertens, H.3    Oostenrijk, D.4    Keestra, M.5    Overdijk, M.6    Labouriau, R.7    Franken, P.8    Frijters, A.9    Nielen, M.10    Rutten, V.11
  • 33
    • 1242272100 scopus 로고    scopus 로고
    • Sequential autophosphorylation steps in the interleukin-1 receptor-associated kinase-1 regulate its availability as an adapter in interleukin-1 signaling
    • Kollewe C., Mackensen A.C., Neumann D., Knop J., Cao P., Li S., Wesche H., Martin M.U. Sequential autophosphorylation steps in the interleukin-1 receptor-associated kinase-1 regulate its availability as an adapter in interleukin-1 signaling. J. Biol. Chem. 2004, 279:5227-5236.
    • (2004) J. Biol. Chem. , vol.279 , pp. 5227-5236
    • Kollewe, C.1    Mackensen, A.C.2    Neumann, D.3    Knop, J.4    Cao, P.5    Li, S.6    Wesche, H.7    Martin, M.U.8
  • 35
    • 43049179999 scopus 로고    scopus 로고
    • LPS/TLR4 signal transduction pathway
    • Lu Y.C., Yeh W.C., Ohashi P.S. LPS/TLR4 signal transduction pathway. Cytokine 2008, 42:145-151.
    • (2008) Cytokine , vol.42 , pp. 145-151
    • Lu, Y.C.1    Yeh, W.C.2    Ohashi, P.S.3
  • 36
    • 0034670047 scopus 로고    scopus 로고
    • Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages
    • Matsuguchi T., Musikacharoen T., Ogawa T., Yoshikai Y. Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages. J. Immunol. 2000, 165:5767-5772.
    • (2000) J. Immunol. , vol.165 , pp. 5767-5772
    • Matsuguchi, T.1    Musikacharoen, T.2    Ogawa, T.3    Yoshikai, Y.4
  • 37
    • 36549003153 scopus 로고    scopus 로고
    • Mycobacterium bovis BCG Toll-like receptors 2 and 4 cooperation increases the innate epithelial immune response
    • Mendez-Samperio P., Belmont L., Miranda E. Mycobacterium bovis BCG Toll-like receptors 2 and 4 cooperation increases the innate epithelial immune response. Arch. Med. Res. 2008, 39:33-39.
    • (2008) Arch. Med. Res. , vol.39 , pp. 33-39
    • Mendez-Samperio, P.1    Belmont, L.2    Miranda, E.3
  • 40
    • 34247566510 scopus 로고    scopus 로고
    • The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
    • O'Neill L.A., Bowie A.G. The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat. Rev. Immunol. 2007, 7:353-364.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 353-364
    • O'Neill, L.A.1    Bowie, A.G.2
  • 41
    • 34548188334 scopus 로고    scopus 로고
    • Differential responses of bovine macrophages to infection with bovine-specific and non-bovine specific mycobacteria
    • Piercy J., Werling D., Coffey T.J. Differential responses of bovine macrophages to infection with bovine-specific and non-bovine specific mycobacteria. Tuberculosis (Edinb.) 2007, 87:415-420.
    • (2007) Tuberculosis (Edinb.) , vol.87 , pp. 415-420
    • Piercy, J.1    Werling, D.2    Coffey, T.J.3
  • 42
  • 44
    • 67349084041 scopus 로고    scopus 로고
    • Searching for proteins of Mycobacterium avium subspecies paratuberculosis with diagnostic potential by comparative qualitative proteomic analysis of mycobacterial tuberculins
    • Santema W., Overdijk M., Barends J., Krijgsveld J., Rutten V., Koets A. Searching for proteins of Mycobacterium avium subspecies paratuberculosis with diagnostic potential by comparative qualitative proteomic analysis of mycobacterial tuberculins. Vet. Microbiol. 2009, 138:191-196.
    • (2009) Vet. Microbiol. , vol.138 , pp. 191-196
    • Santema, W.1    Overdijk, M.2    Barends, J.3    Krijgsveld, J.4    Rutten, V.5    Koets, A.6
  • 45
    • 12844265918 scopus 로고    scopus 로고
    • Minute numbers of contaminant CD8+ T cells or CD11b+CD11c+ NK cells are the source of IFN-gamma in IL-12/IL-18-stimulated mouse macrophage populations
    • Schleicher U., Hesse A., Bogdan C. Minute numbers of contaminant CD8+ T cells or CD11b+CD11c+ NK cells are the source of IFN-gamma in IL-12/IL-18-stimulated mouse macrophage populations. Blood 2005, 105:1319-1328.
    • (2005) Blood , vol.105 , pp. 1319-1328
    • Schleicher, U.1    Hesse, A.2    Bogdan, C.3
  • 46
    • 44949231424 scopus 로고    scopus 로고
    • Analyzing real-time PCR data by the comparative C(T) method
    • Schmittgen T.D., Livak K.J. Analyzing real-time PCR data by the comparative C(T) method. Nat. Protoc. 2008, 3:1101-1108.
    • (2008) Nat. Protoc. , vol.3 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2
  • 47
    • 33747346235 scopus 로고    scopus 로고
    • Signal integration between IFNgamma and TLR signalling pathways in macrophages
    • Schroder K., Sweet M.J., Hume D.A. Signal integration between IFNgamma and TLR signalling pathways in macrophages. Immunobiology 2006, 211:511-524.
    • (2006) Immunobiology , vol.211 , pp. 511-524
    • Schroder, K.1    Sweet, M.J.2    Hume, D.A.3
  • 48
    • 33750037600 scopus 로고    scopus 로고
    • Contribution of interferon-beta to the murine macrophage response to the toll-like receptor 4 agonist, lipopolysaccharide
    • Thomas K.E., Galligan C.L., Newman R.D., Fish E.N., Vogel S.N. Contribution of interferon-beta to the murine macrophage response to the toll-like receptor 4 agonist, lipopolysaccharide. J. Biol. Chem. 2006, 281:31119-31130.
    • (2006) J. Biol. Chem. , vol.281 , pp. 31119-31130
    • Thomas, K.E.1    Galligan, C.L.2    Newman, R.D.3    Fish, E.N.4    Vogel, S.N.5
  • 49
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034
    • Vandesompele J., De Preter K., Pattyn F., Poppe B., Van Roy N., De Paepe A., Speleman F. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 2002, 3. RESEARCH0034.
    • (2002) Genome Biol. , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6    Speleman, F.7
  • 51
    • 77956633972 scopus 로고    scopus 로고
    • Purification and characterization of lipopolysaccharides
    • Wang X., Zhang C., Shi F., Hu X. Purification and characterization of lipopolysaccharides. Subcell. Biochem. 2010, 53:27-51.
    • (2010) Subcell. Biochem. , vol.53 , pp. 27-51
    • Wang, X.1    Zhang, C.2    Shi, F.3    Hu, X.4
  • 52
    • 34548780733 scopus 로고    scopus 로고
    • Pattern recognition receptors in companion and farm animals-the key to unlocking the door to animal disease?
    • Werling D., Coffey T.J. Pattern recognition receptors in companion and farm animals-the key to unlocking the door to animal disease?. Vet. J. 2007, 174:240-251.
    • (2007) Vet. J. , vol.174 , pp. 240-251
    • Werling, D.1    Coffey, T.J.2
  • 53
    • 0347126491 scopus 로고    scopus 로고
    • Differential production of cytokines, reactive oxygen and nitrogen by bovine macrophages and dendritic cells stimulated with Toll-like receptor agonists
    • Werling D., Hope J.C., Howard C.J., Jungi T.W. Differential production of cytokines, reactive oxygen and nitrogen by bovine macrophages and dendritic cells stimulated with Toll-like receptor agonists. Immunology 2004, 111:41-52.
    • (2004) Immunology , vol.111 , pp. 41-52
    • Werling, D.1    Hope, J.C.2    Howard, C.J.3    Jungi, T.W.4
  • 54
    • 33744505197 scopus 로고    scopus 로고
    • Expression of TOLL-like receptors (TLR) by bovine antigen-presenting cells-potential role in pathogen discrimination?
    • Werling D., Piercy J., Coffey T.J. Expression of TOLL-like receptors (TLR) by bovine antigen-presenting cells-potential role in pathogen discrimination?. Vet. Immunol. Immunopathol. 2006, 112:2-11.
    • (2006) Vet. Immunol. Immunopathol. , vol.112 , pp. 2-11
    • Werling, D.1    Piercy, J.2    Coffey, T.J.3
  • 55
    • 0038664380 scopus 로고    scopus 로고
    • The role of Toll-like receptor 2 in microbial disease and immunity
    • Wetzler L.M. The role of Toll-like receptor 2 in microbial disease and immunity. Vaccine 2003, 21(Suppl. 2):S55-60.
    • (2003) Vaccine , vol.21 , Issue.SUPPL. 2
    • Wetzler, L.M.1
  • 56
    • 34848829131 scopus 로고    scopus 로고
    • Granulocyte chemotactic properties of M. tuberculosis versus M. bovis-infected bovine alveolar macrophages
    • Widdison S., Watson M., Piercy J., Howard C., Coffey T.J. Granulocyte chemotactic properties of M. tuberculosis versus M. bovis-infected bovine alveolar macrophages. Mol. Immunol. 2008, 45:740-749.
    • (2008) Mol. Immunol. , vol.45 , pp. 740-749
    • Widdison, S.1    Watson, M.2    Piercy, J.3    Howard, C.4    Coffey, T.J.5
  • 57
    • 0034987326 scopus 로고    scopus 로고
    • BOVIGAM: an in vitro cellular diagnostic test for bovine tuberculosis
    • Wood P.R., Jones S.L. BOVIGAM: an in vitro cellular diagnostic test for bovine tuberculosis. Tuberculosis (Edinb.) 2001, 81:147-155.
    • (2001) Tuberculosis (Edinb.) , vol.81 , pp. 147-155
    • Wood, P.R.1    Jones, S.L.2
  • 60
    • 34248165895 scopus 로고    scopus 로고
    • Cytokine mRNA profiles in bovine macrophages stimulated with Trypanosoma congolense
    • Yoshihara K., Morris A., Iraqi F., Naessens J. Cytokine mRNA profiles in bovine macrophages stimulated with Trypanosoma congolense. J. Vet. Med. Sci. 2007, 69:421-423.
    • (2007) J. Vet. Med. Sci. , vol.69 , pp. 421-423
    • Yoshihara, K.1    Morris, A.2    Iraqi, F.3    Naessens, J.4
  • 61
    • 41649115159 scopus 로고    scopus 로고
    • TLR2-promiscuous or specific? A critical re-evaluation of a receptor expressing apparent broad specificity
    • Zahringer U., Lindner B., Inamura S., Heine H., Alexander C. TLR2-promiscuous or specific? A critical re-evaluation of a receptor expressing apparent broad specificity. Immunobiology 2008, 213:205-224.
    • (2008) Immunobiology , vol.213 , pp. 205-224
    • Zahringer, U.1    Lindner, B.2    Inamura, S.3    Heine, H.4    Alexander, C.5
  • 62
    • 0036510366 scopus 로고    scopus 로고
    • Negative regulation of toll-like receptor-mediated signaling by Tollip
    • Zhang G., Ghosh S. Negative regulation of toll-like receptor-mediated signaling by Tollip. J. Biol. Chem. 2002, 277:7059-7065.
    • (2002) J. Biol. Chem. , vol.277 , pp. 7059-7065
    • Zhang, G.1    Ghosh, S.2
  • 63
    • 45449102067 scopus 로고    scopus 로고
    • Factors determining the formation and release of bioactive IL-12: regulatory mechanisms for IL-12p70 synthesis and inhibition
    • Zhang S., Wang Q. Factors determining the formation and release of bioactive IL-12: regulatory mechanisms for IL-12p70 synthesis and inhibition. Biochem. Biophys. Res. Commun. 2008, 372:509-512.
    • (2008) Biochem. Biophys. Res. Commun. , vol.372 , pp. 509-512
    • Zhang, S.1    Wang, Q.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.