IFN-γ enhances bovine macrophage responsiveness to Mycobacterium bovis: Impact on bacterial replication, cytokine release and macrophage apoptosis

Immunology and Cell Biology

Volumn 83, Issue 6, 2005, Pages 643-650

  Denis, Michel ^a   Wedlock, D Neil ^a   Buddle, Bryce M ^a  

^a AGRESEARCH   (New Zealand)

Author keywords

Apoptosis; Bovine macrophage; IFN ; Mycobacterium bovis; TNF

Indexed keywords

BCG VACCINE; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; NITRIC OXIDE; RECOMBINANT GAMMA INTERFERON; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; BACTERIAL STRAIN; BACTERIAL SURVIVAL; BACTERIOSTASIS; CELL DEATH; CONTROLLED STUDY; COW; CYTOKINE RELEASE; MACROPHAGE; MYCOBACTERIUM BOVIS; NECROSIS; NONHUMAN; STATISTICAL ANALYSIS; VIRULENCE;

ANIMALS; APOPTOSIS; CATTLE; CELLS, CULTURED; CYTOKINES; INTERFERON TYPE II; INTERLEUKIN-12; MACROPHAGES; MYCOBACTERIUM BOVIS; NITRIC OXIDE; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; BACTERIA (MICROORGANISMS); BOVINAE; MYCOBACTERIUM BOVIS;

EID: 30544438071     PISSN: 08189641     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1711.2005.01386.x     Document Type: Article

References (38)

1. Pollock JM, McNair J, Welsh MD et al. Immune responses in bovine tuberculosis. Tuberculosis 2001; 81: 103-107.
2. Aldwell FE, Wedlock DN, Slobbe LJ, Griffin JF, Buddle BM, Buchan GS. In vitro control of Mycobacterium bovis by macrophages. Tuberculosis 2001; 81: 115-23.
3. Denis M. Interferon-gamma-treated murine macrophages inhibit growth of tubercle bacilli via the generation of reactive nitrogen intermediates. Cell Immunol 1991; 132: 150-57.
4. Orme I. Adaptive immunity to mycobacteria. Curr. Opin. Microbiol. 2004; 7: 58-61.
5. Wedlock DN, Aldwell FE, Collins DM, de Lisle GW, Wilson T, Buddle BM. Immune responses induced in cattle by virulent and attenuated Mycobacterium bovis strains: correlation of delayed-type hypersensitivity with ability of strains to grow in macrophages. Infect. Immun. 1999; 67: 2172-7.
6. Waters WR, Palmer MV, Whipple DL, Carlson MP, Nonnecke BJ. Diagnostic implications of antigen-induced gamma interferon, nitric oxide, and tumor necrosis factor alpha production by peripheral blood mononuclear cells from Mycobacterium bovis-infected cattle. Clin. Diagn. Lab. Immunol. 2003; 10: 960-66.
7. Aldwell FE, Wedlock DN, Buddle BM. Sequential activation of alveolar macrophages by IFN-gamma and LPS is required for enhanced growth inhibition of virulent Mycobacterium bovis but not M. Bovis BCG. Immunol. Cell Biol. 1997; 75: 161-6.
8. Ng KH, Watson JD, Prestidge R, Buddle BM. Cytokine mRNA expressed in tuberculin skin test biopsies from BCG-vaccinated and Mycobacterium bovis inoculated cattle. Immunol. Cell Biol. 1995; 73: 362-8.
9. Nonnecke BJ, Waters WR, Foote MR, Horst RL, Fowler MA, Miller BL. In vitro effects of 1,25-dihydroxyvitamin D3 on interferon-gamma and tumor necrosis factor-alpha secretion by blood leukocytes from young and adult cattle vaccinated with Mycobacterium bovis BCG. Int. J. Vitam. Nutr. Res. 2003; 73: 235-44.
10. Garcia I, Guler R, Vesin D et al. Lethal Mycobacterium bovis Bacillus Calmette Guerin infection in nitric oxide synthase 2-deficient mice: cell-mediated immunity requires nitric oxide synthase 2. Lab. Invest. 2000; 80: 1385-97.
11. Juffermans NP, Florquin S, Camoglio L et al. Interleukin-1 signaling is essential for host defense during murine pulmonary tuberculosis. J. Infect. Dis. 2000; 182: 902-908.
12. Turner J, Gonzalez-Juarrero M, Ellis DL et al. In vivo IL-10 production reactivates chronic pulmonary tuberculosis in C57BL/6 mice. J. Immunol. 2002; 169: 6343-51.
13. Feng CG, Kullberg MC, Jankovic D et al. Transgenic mice expressing human interleukin-10 in the antigen-presenting cell compartment show increased susceptibility to infection with Mycobacterium avium associated with decreased macrophage effector function and apoptosis. Infect. Immun. 2002; 70: 6672-9.
14. Jacobs M, Brown N, Allie N, Gulert R, Ryffel B. Increased resistance to mycobacterial infection in the absence of interleukin-10. Immunology 2000; 100: 494-501.
15. Rook GA, Champion BR, Steele J, Varey AM, Stanford JL. I-A restricted activation by T cell lines of anti-tuberculosis activity in murine macrophages. Clin. Exp. Immunol. 1985; 59: 414-20.
16. Nakagawara A, Nathan CF. A simple method for counting adherent cells: application to cultured human monocytes, macrophages and multinucleated giant cells. J. Immunol. Methods 1983; 56: 261-8.
17. Rook GA, Steele J, Umar S, Dockrell HM. A simple method for the solubilisation of reduced NBT, and its use as a colorimetric assay for activation of human macrophages by gamma-interferon. J. Immunol. Methods 1985; 82: 161-7.
18. Wedlock DN, Skinner MA, de Lisle GW, Buddle BM. Control of Mycobacterium bovis infections and the risk to human populations. Microbes Infect. 2002; 4: 471-80.
19. Carpenter E, Fray L, Gormley E. Antigen-specific lymphocytes enhance nitric oxide production in Mycobacterium bovis BCG-infected bovine macrophages. Immunol. Cell Biol. 1998; 76: 363-8.
20. Carpenter E, Fray L, Gormley E. Cellular responses and Mycobacterium bovis BCG growth inhibition by bovine lymphocytes. Immunol. Cell Biol. 1997; 75: 554-60.
21. Zhao B, Collins MT, Czuprynski CJ. Effects of gamma interferon and nitric oxide on the interaction of Mycobacterium avium subsp. paratuberculosis with bovine monocytes. Infect. Immun. 1997; 65: 1761-6.
22. Johnson WJ, Marino PA, Schreiber RD, Adams DO. Sequential activation of murine mononuclear phagocytes for tumor cytolysis: differential expression of markers by macrophages in the several stages of development. J. Immunol. 1983; 131: 1038-43.
23. Flesch IE, Hess JH, Oswald IP, Kaufmann SH. Growth inhibition of Mycobacterium bovis by IFN-gamma stimulated macrophages: regulation by endogenous tumor necrosis factor-alpha and by IL-10. Int. Immunol. 1994; 6: 693-700.
24. Engele M, Stossel E, Castiglione K et al. Induction of TNF in human alveolar macrophages as a potential evasion mechanism of virulent Mycobacterium tuberculosis. J. Immunol. 2002; 168: 1328-37.
25. Balcewicz-Sablinska MK, Keane J, Kornfeld H, Remold HG. Pathogenic Mycobacterium tuberculosis evades apoptosis of host macrophages by release of TNF-R2, resulting in inactivation of TNF-alpha. J. Immunol 1998; 161: 2636-41.
26. Dinarello CA. Anti-cytokine therapeutics and infections. Vaccine 2003; 21: S24-34.
27. Mocellin S, Marincola F, Rossi CR, Nitti D, Lise M. The multi-faceted relationship between IL-10 and adaptive immunity: putting together the pieces of a puzzle. Cytokine Growth Factor Rev. 2004; 15: 61-76.
28. Feng CG, Kullberg MC, Jankovic D et al. Transgenic mice expressing human interleukin-10 in the antigen-presenting cell compartment show increased susceptibility to infection with Mycobacterium avium associated with decreased macrophage effector function and apoptosis. Infect. Immun. 2002; 70: 6672-9.
29. Buza JJ, Hikono H, Mori Y et al. Neutralization of interleukin-10 significantly enhances gamma interferon expression in peripheral blood by stimulation with Johne's purified protein derivative and by infection with Mycobacterium avium subsp. paratuberculosis in experimentally infected cattle with paratuberculosis. Infect. Immun. 2004; 72: 2425-8.
30. Goff WL, O'Rourke KI, Johnson WC, Lacy PA, Davis WC, Wyatt CR. The role of IL-10 in iNOS and cytokine mRNA expression during in vitro differentiation of bovine mononuclear phagocytes. J. Interferon Cytokine Res. 1998; 18: 139-49.
31. Fukutomi Y, Matsuoka M, Minagawa F, Toratani S, McCormick G, Krahenbuhl J. IL-10 treatment of macrophages bolsters intracellular survival of Mycobacterium leprae. Int. J. Lepr. Other Mycobact. Dis. 2004; 72: 16-26.
32. Balcewicz-Sablinska MK, Gan H, Remold HG. Interleukin-10 produced by macrophages inoculated with Mycobacterium avium attenuates mycobacteria-induced apoptosis by reduction of TNF-alpha activity. J. Infect. Dis. 1999; 180: 1230-37.
33. Stober CB, Lammas DA, Li CM, Kumararatne DS, Lightman SL, McArdle CA. ATP-mediated killing of Mycobacterium bovis bacille Calmette-Guerin within human macrophages is calcium dependent and associated with the acidification of mycobacteria-containing phagosomes. J. Immunol. 2001; 166: 6276-86.
34. Jungi TW, Brcic M, Sager H, Dobbelaere DA, Purger A, Roditi I. Antagonistic effects of IL-4 and interferon-gamma (IFN-γ) on inducible nitric oxide synthase expression in bovine macrophages exposed to gram-positive bacteria. Clin. Exp. Immunol. 1997; 109: 431-8.
35. Jungi TW, Valentin-Weigand P, Brcic M. Differential induction of NO synthesis by gram-positive and gram-negative bacteria and their components in bovine monocyte-derived macrophages. Microb. Pathog. 1999; 27: 43-53.
36. Clemens DL. Characterization of the Mycobacterium tuberculosis phagosome. Trends Microbiol. 1996; 4: 113-18.
37. Gomes MS, Dom G, Pedrosa J, Boelaert JR, Appelberg R. Effects of iron deprivation on Mycobacterium avium growth. Tubercle Lung Dis. 1999; 79: 321-8.
38. Cooper AM, Kipnis A, Turner J, Magram J, Ferrante J, Orme IM. Mice lacking bioactive IL-12 can generate protective, antigen-specific cellular responses to mycobacterial infection only if the IL-12 p40 subunit is present. J. Immunol. 2002; 168: 1322-7.