A survey of antiprion compounds reveals the prevalence of non-PrP molecular targets

Journal of Biological Chemistry

Volumn 286, Issue 31, 2011, Pages 27718-27728

  Poncet Montange, Guillaume ^b   St Martin, Susan J ^b   Bogatova, Olga V ^b   Prusiner, Stanley B ^a,b   Shoichet, Brian K ^b   Ghaemmaghami, Sina ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE MOLECULES; BRAIN HOMOGENATES; CELL-BASED SCREENS; CELLULAR LOCALIZATION; CULTURED CELL; DRUG DISCOVERY; EXPRESSION LEVELS; IN-VITRO; ISOFORMS; MOLECULAR TARGETS; PRION DISEASE; PRION PROPAGATION; PRION PROTEIN;

MOLECULAR PHYSICS;

NEURODEGENERATIVE DISEASES;

3 DEOXY 3BETA HYDROXYANGOLENSIC ACID METHYL ESTER; 4' HYDROXY CHALCONE; AMCINONIDE; ANTIVIRUS AGENT; CHRYSANTHELLIN A; DAIDZEIN; DEHYDROVARIABILIN; DIGITONIN; DIGITOXIN; GENISTEIN; IRIGENIN; ISOLIQUIRITIGENIN; MEVINOLIN; PRION PROTEIN; PROFENAMINE; RETINOIC ACID; ROSUVASTATIN; TRIACETYLRESVERATROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CIRCULAR DICHROISM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DENATURATION; DRUG ACTIVITY; DRUG STRUCTURE; ENZYME KINETICS; GLYCOSYLATION; HYDROPHOBICITY; ISOTHERMAL TITRATION CALORIMETRY; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PRION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN PURIFICATION; PROTEIN TARGETING;

ANIMALS; CALORIMETRY; CIRCULAR DICHROISM; ENZYME-LINKED IMMUNOSORBENT ASSAY; HYDROLYSIS; IMMUNOHISTOCHEMISTRY; KINETICS; MICE; PRPSC PROTEINS;

EID: 79960982077     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.234393     Document Type: Article

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