Structural bases of stability-function tradeoffs in enzymes

Journal of Molecular Biology

Volumn 321, Issue 2, 2002, Pages 285-296

  Beadle, Beth M ^a   Shoichet, Brian K ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Enzyme function; Enzyme stability; Stability function tradeoffs; X ray crystal structure; lactamase

Indexed keywords

MUTANT PROTEIN; PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME STABILITY; ENZYME STRUCTURE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; REGULATORY MECHANISM; STEREOSPECIFICITY;

EID: 0036384211     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00599-5     Document Type: Article

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