-
1
-
-
56749176437
-
Cadherins and cancer: How does cadherin dysfunction promote tumor progression?
-
Jeanes A, Gottardi CJ, Yap AS,. Cadherins and cancer: how does cadherin dysfunction promote tumor progression? Oncogene 2008; 27: 6920-9.
-
(2008)
Oncogene
, vol.27
, pp. 6920-6929
-
-
Jeanes, A.1
Gottardi, C.J.2
Yap, A.S.3
-
2
-
-
77954214841
-
Striking the target in Wnt-y conditions: Intervening in Wnt signaling during cancer progression
-
Camilli TC, Weeraratna AT,. Striking the target in Wnt-y conditions: intervening in Wnt signaling during cancer progression. Biochem Pharmacol 2010; 80: 702-11.
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 702-711
-
-
Camilli, T.C.1
Weeraratna, A.T.2
-
3
-
-
0035479835
-
New aspects of Wnt signaling pathways in higher vertebrates
-
DOI 10.1016/S0959-437X(00)00231-8, PII S0959437X00002318
-
Huelsken J, Birchmeier W,. New aspects of Wnt signaling pathways in higher vertebrates. Curr Opin Genet Dev 2001; 11: 547-53. (Pubitemid 32800729)
-
(2001)
Current Opinion in Genetics and Development
, vol.11
, Issue.5
, pp. 547-553
-
-
Huelsken, J.1
Birchmeier, W.2
-
4
-
-
0032885751
-
Nuclear accumulation of mutated β-catenin in hepatocellular carcinoma is associated with increased cell proliferation
-
Nhieu JT, Renard CA, Wei Y, Cherqui D, Zafrani ES, Buendia MA,. Nuclear accumulation of mutated β-catenin in hepatocellular carcinoma is associated with increased cell proliferation. Am J Pathol 1999; 155: 703-10. (Pubitemid 29426815)
-
(1999)
American Journal of Pathology
, vol.155
, Issue.3
, pp. 703-710
-
-
Van Nhieu, J.T.1
Renard, C.A.2
Wei, Y.3
Cherqui, D.4
Zafrani, E.S.5
Buendia, M.A.6
-
5
-
-
0034644526
-
Linking colorectal cancer to Wnt signaling
-
Bienz M, Clevers H,. Linking colorectal cancer to Wnt signaling. Cell 2000; 103: 311-3.
-
(2000)
Cell
, vol.103
, pp. 311-313
-
-
Bienz, M.1
Clevers, H.2
-
6
-
-
0038135028
-
Loss of beta-catenin expression in metastatic gastric cancer
-
DOI 10.1200/JCO.2003.10.017
-
Ebert MP, Yu J, Hoffmann J, Rocco A, Röcken C, Kahmann S, Müller O, Korc M, Sung JJ, Malfertheiner P,. Loss of beta-catenin expression in metastatic gastric cancer. J Clin Oncol 2003; 21: 1708-14. (Pubitemid 46638581)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.9
, pp. 1708-1714
-
-
Ebert, M.P.A.1
Yu, J.2
Hoffmann, J.3
Rocco, A.4
Rocken, C.5
Kahmann, S.6
Muller, O.7
Korc, M.8
Sung, J.J.9
Malfertheiner, P.10
-
7
-
-
0034614941
-
Regulation of cadherin adhesive activity
-
Gumbiner BM,. Regulation of cadherin adhesive activity. J Cell Biol 2000; 148: 399-403.
-
(2000)
J Cell Biol
, vol.148
, pp. 399-403
-
-
Gumbiner, B.M.1
-
8
-
-
66349121353
-
Classical cadherins control nucleus and centrosome position and cell polarity
-
Dupin I, Camand E, Etienne-Manneville S,. Classical cadherins control nucleus and centrosome position and cell polarity. J Cell Biol 2009; 185: 779-86.
-
(2009)
J Cell Biol
, vol.185
, pp. 779-786
-
-
Dupin, I.1
Camand, E.2
Etienne-Manneville, S.3
-
9
-
-
0029865275
-
Expression of E-cadherin in primary and metastatic prostate cancer
-
Cheng L, Nagabhushan M, Pretlow TP,. Epression of E-cadherin in primary and metastatic prostate cancer. Am J Pathol 1996; 148: 1375-80. (Pubitemid 26135881)
-
(1996)
American Journal of Pathology
, vol.148
, Issue.5
, pp. 1375-1380
-
-
Cheng, L.1
Nagabhushan, M.2
Pretlow, T.P.3
Amini, S.B.4
Pretlow, T.G.5
-
10
-
-
0031830664
-
Inactivation of the E-cadherin-mediated cell adhesion system in human cancers
-
Hirohashi S,. Inactivation of the E-cadherin-mediated cell adhesion system in human cancers. Am J Pathol 1998; 153: 333-9. (Pubitemid 28373643)
-
(1998)
American Journal of Pathology
, vol.153
, Issue.2
, pp. 333-339
-
-
Hirohashi, S.1
-
11
-
-
23844489449
-
P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation
-
Paredes J, Albergaria A, Oliveira JT, Jeronimo C,. P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation. Clin Cancer Res 2005; 11: 5869-76.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5869-5876
-
-
Paredes, J.1
Albergaria, A.2
Oliveira, J.T.3
Jeronimo, C.4
-
12
-
-
0035947772
-
E-cadherin suppresses cellular transformation by inhibiting β-catenin signaling in an adhesion independent manner
-
Gottardi CJ, Wong E, Gumbiner BM,. E-cadherin suppresses cellular transformation by inhibiting β-catenin signaling in an adhesion independent manner. J Cell Biol 2001; 153: 1049-60.
-
(2001)
J Cell Biol
, vol.153
, pp. 1049-1060
-
-
Gottardi, C.J.1
Wong, E.2
Gumbiner, B.M.3
-
13
-
-
2342430345
-
LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling: Arrows point the way
-
DOI 10.1242/dev.01117
-
He X, Semenov M, Tamai K, Zeng X,. LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling: arrows point the way. Development 2004; 131: 1663-77. (Pubitemid 38559836)
-
(2004)
Development
, vol.131
, Issue.8
, pp. 1663-1677
-
-
He, X.1
Semenov, M.2
Tamai, K.3
Zeng, X.4
-
14
-
-
1642564513
-
A Mechanism for Wnt Coreceptor Activation
-
DOI 10.1016/S1097-2765(03)00484-2
-
Tamai K, Zeng X, Liu C, Zhang X, Harada Y, Chang, Z., He X,. A mechanism for Wnt coreceptor activation. Mol Cell 2004; 13: 149-56. (Pubitemid 38117123)
-
(2004)
Molecular Cell
, vol.13
, Issue.1
, pp. 149-156
-
-
Tamai, K.1
Zeng, X.2
Liu, C.3
Zhang, X.4
Harada, Y.5
Chang, Z.6
He, X.7
-
15
-
-
28644439005
-
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
-
DOI 10.1038/nature04185
-
Zeng X, Tamai K, Doble B, Li S, Huang H, Habas R, Okamura H, Woodgett J, He X,. A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation. Nature 2005; 438: 873-7. (Pubitemid 41753071)
-
(2005)
Nature
, vol.438
, Issue.7069
, pp. 873-877
-
-
Zeng, X.1
Tamai, K.2
Doble, B.3
Li, S.4
Huang, H.5
Habas, R.6
Okamura, H.7
Woodgett, J.8
He, X.9
-
16
-
-
0034601478
-
Distinct β-catenins mediate adhesion and signalling functions in C. elegans
-
DOI 10.1038/35020099
-
Korswagen HC, Herman MA, Clevers HC,. Distinct beta-catenins mediate adhesion and signalling functions in C. elegans. Nature 2000; 406: 527-32. (Pubitemid 30625738)
-
(2000)
Nature
, vol.406
, Issue.6795
, pp. 527-532
-
-
Korswagen, H.C.1
Herman, M.A.2
Clevers, H.C.3
-
17
-
-
18244427021
-
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway
-
DOI 10.1016/S1097-2765(01)00224-6
-
Mao J, Wang J, Liu B, Pan W, Farr GH, Flynn C, Yuan H, Takada S, Kimelman D, Li L, Wu D,. Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol Cell 2001; 7: 801-9. (Pubitemid 32436440)
-
(2001)
Molecular Cell
, vol.7
, Issue.4
, pp. 801-809
-
-
Mao, J.1
Wang, J.2
Liu, B.3
Pan, W.4
Farr III, G.H.5
Flynn, C.6
Yuan, H.7
Takada, S.8
Kimelman, D.9
Li, L.10
Wu, D.11
-
18
-
-
0034678610
-
The p300/CBP acetyltransferases function as transcriptional coactivators of β-catenin in vertebrates
-
Hecht A, Vleminckx K, Stemmler MP, van Roy F, Kemler R,. The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates. EMBO J 2000; 19: 1839-50. (Pubitemid 30204395)
-
(2000)
EMBO Journal
, vol.19
, Issue.8
, pp. 1839-1850
-
-
Hecht, A.1
Vleminckx, K.2
Stemmler, M.P.3
Van Roy, F.4
Kemler, R.5
-
19
-
-
62849106337
-
Beta-catenin hits chromatin: Regulation of Wnt target gene activation
-
Mosimann C, Hausmann G, Basler K,. Beta-catenin hits chromatin: regulation of Wnt target gene activation. Nat Rev Mol Cell Biol 2009; 10: 276-86.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 276-286
-
-
Mosimann, C.1
Hausmann, G.2
Basler, K.3
-
21
-
-
77956288500
-
Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis
-
Henderson WR, Jr, Chi EY, Ye X, Nguyen C, Tien YT, Zhou B, Borok Z, Knight DA, Kahn M,. Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis. Proc Natl Acad Sci USA 2010; 107: 14309-14.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 14309-14314
-
-
Henderson Jr., W.R.1
Chi, E.Y.2
Ye, X.3
Nguyen, C.4
Tien, Y.T.5
Zhou, B.6
Borok, Z.7
Knight, D.A.8
Kahn, M.9
-
22
-
-
1642512639
-
Small-molecule antagonists of the oncogenic Tcf/β-catenin protein complex
-
DOI 10.1016/S1535-6108(03)00334-9
-
Lepourcelet M, Chen YN, France DS, Wang H, Crews P, Petersen F, Bruseo C, Wood AW, Shivdasani RA,. Small-molecule antagonists of the oncogenic Tcf/β-catenin protein complex. Cancer Cell 2004; 5: 91-102. (Pubitemid 38121599)
-
(2004)
Cancer Cell
, vol.5
, Issue.1
, pp. 91-102
-
-
Lepourcelet, M.1
Chen, Y.-N.P.2
France, D.S.3
Wang, H.4
Crews, P.5
Petersen, F.6
Bruseo, C.7
Wood, A.W.8
Shivdasani, R.A.9
-
23
-
-
77951675861
-
Small molecule inhibitors of Wnt/beta-catenin/lef-1 signaling induces apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo
-
Gandhirajan RK, Staib PA, Minke K, Gehrke I, Plickert G, Schlösser A, Schmitt EK, Hallek M, Kreuzer KA,. Small molecule inhibitors of Wnt/beta-catenin/lef-1 signaling induces apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo. Neoplasia 2010; 12: 326-35.
-
(2010)
Neoplasia
, vol.12
, pp. 326-335
-
-
Gandhirajan, R.K.1
Staib, P.A.2
Minke, K.3
Gehrke, I.4
Plickert, G.5
Schlösser, A.6
Schmitt, E.K.7
Hallek, M.8
Kreuzer, K.A.9
-
24
-
-
77951230705
-
Small molecule antagonists of Tcf4/beta-catenin complex inhibit the growth of HCC cells in vitro and in vivo
-
Wei W, Chua MS, Grepper S, So S,. Small molecule antagonists of Tcf4/beta-catenin complex inhibit the growth of HCC cells in vitro and in vivo. Int J Cancer 2010; 126: 2426-36.
-
(2010)
Int J Cancer
, vol.126
, pp. 2426-2436
-
-
Wei, W.1
Chua, M.S.2
Grepper, S.3
So, S.4
-
25
-
-
59049101982
-
Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model
-
Chien AJ, Moore EC, Lonsdorf AS, Kulikauskas RM, Rothberg BG, Berger AJ, Major MB, Hwang ST, Rimm DL, Moon RT,. Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model. Proc Natl Acad Sci USA 2009; 106: 1193-8.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 1193-1198
-
-
Chien, A.J.1
Moore, E.C.2
Lonsdorf, A.S.3
Kulikauskas, R.M.4
Rothberg, B.G.5
Berger, A.J.6
Major, M.B.7
Hwang, S.T.8
Rimm, D.L.9
Moon, R.T.10
-
26
-
-
77956266718
-
A re-evaluation of the "oncogenic" nature of Wnt/beta-catenin signaling in melanoma and other cancers
-
Lucero OM, Dawson DW, Moon RT, Chien AJ,. A re-evaluation of the "oncogenic" nature of Wnt/beta-catenin signaling in melanoma and other cancers. Curr Oncol Rep 2010; 12: 314-8.
-
(2010)
Curr Oncol Rep
, vol.12
, pp. 314-318
-
-
Lucero, O.M.1
Dawson, D.W.2
Moon, R.T.3
Chien, A.J.4
-
27
-
-
0032492954
-
Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β
-
Hart MJ, de los Santos R, Albert IN, Rubinfeld B, Polakis P,. Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta. Curr Biol 1998; 8: 573-81. (Pubitemid 28222891)
-
(1998)
Current Biology
, vol.8
, Issue.10
, pp. 573-581
-
-
Hart, M.J.1
De Los Santos, R.2
Albert, I.N.3
Rubinfeld, B.4
Polakis, P.5
-
28
-
-
0033068154
-
The SCF(β-TRCP)-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IκBα and β-catenin and stimulates IκBα ubiquitination in vitro
-
Winston JT, Strack P, Beer-Romero P, Chu CY, Elledge SJ, Harper JW,. The SCFβ-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and β-catenin and stimulates IkappaBalpha ubiquitination in vitro. Genes Dev 1999; 13: 270-83. (Pubitemid 29095799)
-
(1999)
Genes and Development
, vol.13
, Issue.3
, pp. 270-283
-
-
Winston, J.T.1
Strack, P.2
Beer-Romero, P.3
Chu, C.Y.4
Elledge, S.J.5
Harper, J.W.6
-
29
-
-
0033602227
-
The F-box protein β-TrCP associates with phosphorylated β-catenin and regulates its activity in the cell
-
DOI 10.1016/S0960-9822(99)80091-8
-
Hart M, Concordet JP, Lassot I, Albert I, del los Santos R, Durand H, Perret C, Rubinfeld B, Margottin F, Benarous R, Polakis P,. The F-box protein beta-TrCP associates with phosphorylated β-catenin and regulates its activity in the cell. Curr Biol 1999; 9: 207-10. (Pubitemid 29120385)
-
(1999)
Current Biology
, vol.9
, Issue.4
, pp. 207-210
-
-
Hart, M.1
Concordet, J.-P.2
Lassot, I.3
Albert, I.4
Del Los Santos, R.5
Durand, H.6
Perret, C.7
Rubinfeld, B.8
Margottin, F.9
Benarous, R.10
Polakis, P.11
-
30
-
-
0033522491
-
An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of β-catenin
-
DOI 10.1093/emboj/18.9.2401
-
Kitagawa M, Hatakeyama S, Shirane M, Matsumoto M, Ishida N, Hattori K, Nakamichi I, Kikuchi A, Nakayama K, Nakayama K,. An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of β-catenin. EMBO J 1999; 18: 2401-10. (Pubitemid 29213274)
-
(1999)
EMBO Journal
, vol.18
, Issue.9
, pp. 2401-2410
-
-
Kitagawa, M.1
Hatakeyama, S.2
Shirane, M.3
Matsumoto, M.4
Ishida, N.5
Hattori, K.6
Nakamichi, I.7
Kikuchi, A.8
Nakayama, K.-I.9
Nakayama, K.10
-
31
-
-
0037155691
-
Control of β-catenin phosphorylation/degradation by a dual-kinase mechanism
-
DOI 10.1016/S0092-8674(02)00685-2
-
Liu C, Li Y, Semenov M, Han C, Baeg GH, Tan Y, Zhang Z, Lin X, He X,. Control of β-Catenin phosphorylation/degradation by a dual-kinase mechanism. Cell 2002; 108: 837-47. (Pubitemid 34327534)
-
(2002)
Cell
, vol.108
, Issue.6
, pp. 837-847
-
-
Liu, C.1
Li, Y.2
Semenov, M.3
Han, C.4
Baeg, G.-H.5
Tan, Y.6
Zhang, Z.7
Lin, X.8
He, X.9
-
32
-
-
0033200392
-
A functional interaction between the histone deacetylase Rpd3 and the corepressor Groucho in Drosophila development
-
DOI 10.1101/gad.13.17.2218
-
Chen G, Fernandez J, Mische S, Courey AJ,. A functional interaction between the histone deacetylase Rpd3 and the corepressor groucho in Drosophila development. Genes Dev 1999; 13: 2218-30. (Pubitemid 29426727)
-
(1999)
Genes and Development
, vol.13
, Issue.17
, pp. 2218-2230
-
-
Chen, G.1
Fernandez, J.2
Mische, S.3
Courey, A.J.4
-
33
-
-
18744400798
-
β-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation
-
DOI 10.1038/nsmb912
-
Daniels DL, Weis WI,. Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation. Nat Struct Mol Biol 2005; 12: 364-71. (Pubitemid 43093092)
-
(2005)
Nature Structural and Molecular Biology
, vol.12
, Issue.4
, pp. 364-371
-
-
Daniels, D.L.1
Weis, W.I.2
-
34
-
-
0032808135
-
XCtBP is a XTcf-3 co-repressor with roles throughout Xenopus development
-
Brannon M, Brown JD, Bates R, Kimelman D, Moon RT,. XCtBP is a XTcf-3 co-repressor with roles throughout Xenopus development. Development 1999; 126: 3159-70. (Pubitemid 29378179)
-
(1999)
Development
, vol.126
, Issue.14
, pp. 3159-3170
-
-
Brannon, M.1
Brown, J.D.2
Bates, R.3
Kimelman, D.4
Moon, R.T.5
-
35
-
-
70350510862
-
Phosphorylation of PPP(S/T)P motif of the free LRP6 intracellular domain is not required to activate the Wnt/β-catenin pathway and attenuate GSK3βactivity
-
Beagle B, Mi K, Johnson GVW,. Phosphorylation of PPP(S/T)P motif of the free LRP6 intracellular domain is not required to activate the Wnt/β-catenin pathway and attenuate GSK3βactivity. J Cell Biol 2009; 108: 886-95.
-
(2009)
J Cell Biol
, vol.108
, pp. 886-895
-
-
Beagle, B.1
Mi, K.2
Johnson, G.V.W.3
-
36
-
-
33847341660
-
Wnt11/β-catenin signaling in both oocytes and early embroys acts through LRP6-mediated regulation of axin
-
DOI 10.1242/dev.02739
-
Kofron M, Birsoy B, Houston D, Tao Q, Wylie C, Heasman J,. Wnt11/beta-catenin signaling in both oocytes and early embryos acts through LRP6-mediated regulation of axin. Development 2007; 134: 503-13. (Pubitemid 46332487)
-
(2007)
Development
, vol.134
, Issue.3
, pp. 503-513
-
-
Kofron, M.1
Birsoy, B.2
Houston, D.3
Tao, Q.4
Wylie, C.5
Heasman, J.6
-
37
-
-
19344365948
-
The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway
-
Lee E, Salic A, Kruger R, Heinrich R, Kirschner MW,. The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway. PLoS Biol 2004; 2: E89.
-
(2004)
PLoS Biol
, vol.2
-
-
Lee, E.1
Salic, A.2
Kruger, R.3
Heinrich, R.4
Kirschner, M.W.5
-
38
-
-
1642380413
-
Rethinking WNT signaling
-
DOI 10.1016/j.tig.2004.02.003, PII S0168952504000393
-
Tolwinski NS, Wieschaus E,. Rethinking WNT signaling. Trends genet 2004; 20: 177-81. (Pubitemid 38369188)
-
(2004)
Trends in Genetics
, vol.20
, Issue.4
, pp. 177-181
-
-
Tolwinski, N.S.1
Wieschaus, E.2
-
39
-
-
45849104800
-
LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of β-catenin
-
DOI 10.1073/pnas.0803025105
-
Cselenyi CS, Jernigan KK, Tahinci E, Thorne CA, Lee LA, Lee E,. LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3′s phosphorylation of β-catenin. Proc Natl Acad Sci USA 2008; 105: 8032-7. (Pubitemid 351904702)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.23
, pp. 8032-8037
-
-
Cselenyi, C.S.1
Jernigan, K.K.2
Tahinci, E.3
Thorne, C.A.4
Lee, L.A.5
Lee, E.6
-
40
-
-
58149185151
-
Direct Inhibition of GSK3β by the phosphorylated cytoplasmic domain of LRP6 in Wnt/β-catenin signaling
-
Piao S, Lee SH, Kim H, Yum S, Stamos JL, Xu Y, Lee SJ, Lee J, Oh S, Han JK, Park BJ, Weis WI, et al. Direct Inhibition of GSK3β by the phosphorylated cytoplasmic domain of LRP6 in Wnt/β-catenin signaling. PLoS One 2008; 3: e4046.
-
(2008)
PLoS One
, vol.3
-
-
Piao, S.1
Lee, S.H.2
Kim, H.3
Yum, S.4
Stamos, J.L.5
Xu, Y.6
Lee, S.J.7
Lee, J.8
Oh, S.9
Han, J.K.10
Park, B.J.11
Weis, W.I.12
-
41
-
-
62849125293
-
Inhibition of GSK3 phosphorylation of β-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6
-
Wu G, Huang H, Abreu JG, He X,. Inhibition of GSK3 phosphorylation of β-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6. PLoS One 2009; 4: e4926.
-
(2009)
PLoS One
, vol.4
-
-
Wu, G.1
Huang, H.2
Abreu, J.G.3
He, X.4
-
42
-
-
27844516613
-
Rapid, Wnt-induced changes in GSK3β associations that regulate β-catenin stabilization are mediated by Gα proteins
-
DOI 10.1016/j.cub.2005.10.050, PII S0960982205013035
-
Liu X, Rubin JS, Kimmel AR,. Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins. Curr Biol 2005; 15: 1989-97. (Pubitemid 41654621)
-
(2005)
Current Biology
, vol.15
, Issue.22
, pp. 1989-1997
-
-
Liu, X.1
Rubin, J.S.2
Kimmel, A.R.3
-
43
-
-
0037468573
-
Expression profile of genes from 12p in testicular germ cell tumors of adolescents and adults associated with i(12p) and amplification at 12p11.2-p12.1
-
DOI 10.1038/sj.onc.1206302
-
Rodriguez S, Jafer O, Goker H, Summersgill BM, Zafarana G, Gillis AJ, van Gurp RJ, Oosterhuis JW, Lu YJ, Huddart R, Cooper CS, Clark J, et al. Expression profile of genes from 12p in testicular germ cell tumors of adolescents and adults associated with i(12p) and amplification at 12p11.2-p12.1. Oncogene 2003; 22: 1880-91. (Pubitemid 36513147)
-
(2003)
Oncogene
, vol.22
, Issue.12
, pp. 1880-1891
-
-
Rodriguez, S.1
Jafer, O.2
Goker, H.3
Summersgill, B.M.4
Zafarana, G.5
Gillis, A.J.M.6
Van Gurp, R.J.H.L.M.7
Oosterhuis, J.W.8
Lu, Y.-J.9
Huddart, R.10
Cooper, C.S.11
Clark, J.12
Looijenga, L.H.J.13
Shipley, J.M.14
-
44
-
-
7944230668
-
An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells
-
DOI 10.1016/j.ccr.2004.09.032, PII S1535610804003046
-
Bafico A, Liu G, Goldin L, Harris V, Aaronson SA,. An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells. Cancer Cell 2004; 6: 497-506. (Pubitemid 39469985)
-
(2004)
Cancer Cell
, vol.6
, Issue.5
, pp. 497-506
-
-
Bafico, A.1
Liu, G.2
Goldin, L.3
Harris, V.4
Aaronson, S.A.5
-
45
-
-
75749104600
-
Wnt signaling activation and mammary gland hyperplasia in MMTV-LRP6 transgenic mice: Implication for breast cancer tumorigenesis
-
Zhang J, Li Y, Liu Q, Lu W, Bu G,. Wnt signaling activation and mammary gland hyperplasia in MMTV-LRP6 transgenic mice: implication for breast cancer tumorigenesis. Oncogene 2010; 29: 539-49.
-
(2010)
Oncogene
, vol.29
, pp. 539-549
-
-
Zhang, J.1
Li, Y.2
Liu, Q.3
Lu, W.4
Bu, G.5
-
46
-
-
15044348490
-
The links between axin and carcinogenesis
-
DOI 10.1136/jcp.2003.009506
-
Salahshor S, Woodgett JR,. The links between axin and carcinogenesis. J Clin Pathol 2005; 58: 225-36. (Pubitemid 40380314)
-
(2005)
Journal of Clinical Pathology
, vol.58
, Issue.3
, pp. 225-236
-
-
Salahshor, S.1
Woodgett, J.R.2
-
47
-
-
50049097448
-
Intrinsic disorder in scaffold proteins: Getting more from less
-
Cortese MS, Uversky VN, Dunker AK,. Intrinsic disorder in scaffold proteins: getting more from less. Prog Biophys Mol Biol 2008; 98: 85-106.
-
(2008)
Prog Biophys Mol Biol
, vol.98
, pp. 85-106
-
-
Cortese, M.S.1
Uversky, V.N.2
Dunker, A.K.3
-
48
-
-
0033565533
-
Wnt-induced dephosphorylation of Axin releases β-catenin from the Axin complex
-
Willert K, Shibamoto S, Nusse R,. Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex. Genes Dev 1999; 13: 1768-73. (Pubitemid 29353044)
-
(1999)
Genes and Development
, vol.13
, Issue.14
, pp. 1768-1773
-
-
Willert, K.1
Shibamoto, S.2
Nusse, R.3
-
49
-
-
0033574527
-
Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability
-
Yamamoto H, Kishida S, Kishida M, Ikeda S, Takada S, Kikuchi A,. Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability. J Biol Chem 1999; 274: 10681-4.
-
(1999)
J Biol Chem
, vol.274
, pp. 10681-10684
-
-
Yamamoto, H.1
Kishida, S.2
Kishida, M.3
Ikeda, S.4
Takada, S.5
Kikuchi, A.6
-
50
-
-
41549115361
-
Wnt/β-catenin signaling: New (and old) players and new insights
-
Huang H, He X,. Wnt/β-catenin signaling: new (and old) players and new insights. Curr Opin Cell Biol 2008; 20: 119-25.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 119-125
-
-
Huang, H.1
He, X.2
-
51
-
-
33947600085
-
Protein phosphatase 1 regulates assembly and function of the β-catenin degradation complex
-
DOI 10.1038/sj.emboj.7601607, PII 7601607
-
Luo W, Peterson A, Garcia BA, Coombs G, Kofah B, Heinrich R,. Protein phosphatase 1 regulates assembly and function of the β-catenin degradation complex. EMBO J 2007; 26: 1511-21. (Pubitemid 46480933)
-
(2007)
EMBO Journal
, vol.26
, Issue.6
, pp. 1511-1521
-
-
Luo, W.1
Peterson, A.2
Garcia, B.A.3
Coombs, G.4
Kofahl, B.5
Heinrich, R.6
Shabanowitz, J.7
Hunt, D.F.8
Yost, H.J.9
Virshup, D.M.10
-
52
-
-
69249202259
-
Dab2 stabilizes Axin and attenuates Wnt/β-catenin signaling by preventing protein phosphatase 1 (PP1)-Axin interactions
-
Jiang Y, Luo W, Howe PH,. Dab2 stabilizes Axin and attenuates Wnt/β-catenin signaling by preventing protein phosphatase 1 (PP1)-Axin interactions. Oncogene 2009; 28: 2999-3007.
-
(2009)
Oncogene
, vol.28
, pp. 2999-3007
-
-
Jiang, Y.1
Luo, W.2
Howe, P.H.3
-
53
-
-
77956646565
-
Destruction of a destructor: A new avenue for cancer therapeutics targeting the Wnt pathway
-
Liu CM, He X,. Destruction of a destructor: a new avenue for cancer therapeutics targeting the Wnt pathway. J Mol Cell Biol 2010; 2: 70-3.
-
(2010)
J Mol Cell Biol
, vol.2
, pp. 70-73
-
-
Liu, C.M.1
He, X.2
-
54
-
-
70349695861
-
Tankyrase inhibition stabilizes axin and antagonizes Wnt signaling
-
Huang SM, Mishina YM, Liu S, Cheung A, Stegmeier F, Michaud GA, Charlat O, Wiellette E, Zhang Y, Wiessner S, Hild M, Shi X, et al. Tankyrase inhibition stabilizes axin and antagonizes Wnt signaling. Nature 2009; 461: 614-20.
-
(2009)
Nature
, vol.461
, pp. 614-620
-
-
Huang, S.M.1
Mishina, Y.M.2
Liu, S.3
Cheung, A.4
Stegmeier, F.5
Michaud, G.A.6
Charlat, O.7
Wiellette, E.8
Zhang, Y.9
Wiessner, S.10
Hild, M.11
Shi, X.12
-
55
-
-
36749045682
-
Tankyrase function at telomeres, spindle poles, and beyond
-
DOI 10.1016/j.biochi.2007.07.012, PII S0300908407001885, Telomeres and Telomerase: from Basic Research to Clinical Applications
-
Hsiao SJ, Smith S,. Tankyrase function at telomeres, spindle poles, and beyond. Biochimie 2008; 90: 83-92. (Pubitemid 350216209)
-
(2008)
Biochimie
, vol.90
, Issue.1
, pp. 83-92
-
-
Hsiao, S.J.1
Smith, S.2
-
56
-
-
58249122326
-
Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
-
Chen B, Dodge ME, Tang W, Lu J, Ma Z, Fan CW, Wei S, Hao W, Kilgore J, Williams NS, Roth MG, Amatruda JF, et al. Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nat Chem Biol 2009; 5: 100-7.
-
(2009)
Nat Chem Biol
, vol.5
, pp. 100-107
-
-
Chen, B.1
Dodge, M.E.2
Tang, W.3
Lu, J.4
Ma, Z.5
Fan, C.W.6
Wei, S.7
Hao, W.8
Kilgore, J.9
Williams, N.S.10
Roth, M.G.11
Amatruda, J.F.12
-
57
-
-
46049085203
-
The APC Tumor Suppressor Inhibits DNA Replication by Directly Binding to DNA via Its Carboxyl Terminus
-
DOI 10.1053/j.gastro.2008.03.074, PII S0016508508005702
-
Qian J, Sarnaik AA, Bonney TM, Keirsey J, Combs KA, Steigerwald K, Acharya S, Behbehani GK, Barton MC, Lowy AM, Groden J,. The APC tumor suppressor inhibits DNA replication by directly binding to DNA via its carboxyl-terminus. Gastroenterology 2008; 135: 152-62. (Pubitemid 351899022)
-
(2008)
Gastroenterology
, vol.135
, Issue.1
, pp. 152-162
-
-
Qian, J.1
Sarnaik, A.A.2
Bonney, T.M.3
Keirsey, J.4
Combs, K.A.5
Steigerwald, K.6
Acharya, S.7
Behbehani, G.K.8
Barton, M.C.9
Lowy, A.M.10
Groden, J.11
-
58
-
-
77954422924
-
Adenomatous polyposis coli protein nucleates actin assembly and synergizes with the formin mDia1
-
Okada K, Bartolini F, Deaconescu AM, Moseley JB, Dogic Z, Grigorieff N,. Adenomatous polyposis coli protein nucleates actin assembly and synergizes with the formin mDia1. J Cell Biol 2010; 189: 1087-96.
-
(2010)
J Cell Biol
, vol.189
, pp. 1087-1096
-
-
Okada, K.1
Bartolini, F.2
Deaconescu, A.M.3
Moseley, J.B.4
Dogic, Z.5
Grigorieff, N.6
-
59
-
-
77956310444
-
Topoisomerase IIαbinding domains of adenomatous polyposis coli influence cell cycle progression and aneuploidy
-
Wang Y, Coffey RJ, Osheroff N, Neufeld KL,. Topoisomerase IIαbinding domains of adenomatous polyposis coli influence cell cycle progression and aneuploidy. PLoS One 2010; 5: e9994.
-
(2010)
PLoS One
, vol.5
-
-
Wang, Y.1
Coffey, R.J.2
Osheroff, N.3
Neufeld, K.L.4
-
60
-
-
77956637544
-
DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC
-
Bradley CR, David AJ,. DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC. Cell 2010; 142: 930-42.
-
(2010)
Cell
, vol.142
, pp. 930-942
-
-
Bradley, C.R.1
David, A.J.2
-
61
-
-
56849086074
-
APC is essential for targeting phosphorylated β-catenin to the SCF(β-TrCP) ubiquitin ligase
-
Su Y, Fu C, Ishikawa S, Stella A, Kojima M, Shitoh K, Schreiber EM, Day BW, Liu B,. APC is essential for targeting phosphorylated β-catenin to the SCF(β-TrCP) ubiquitin ligase. Mol Cell 2008; 32: 652-61.
-
(2008)
Mol Cell
, vol.32
, pp. 652-661
-
-
Su, Y.1
Fu, C.2
Ishikawa, S.3
Stella, A.4
Kojima, M.5
Shitoh, K.6
Schreiber, E.M.7
Day, B.W.8
Liu, B.9
-
62
-
-
0344442773
-
Crystal structure of a β-catenin/Axin complex suggests a mechanism for the β-catenin destruction complex
-
DOI 10.1101/gad.1142603
-
Xing Y, Clements WK, Kimelman D, Xu W,. Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex. Genes Dev 2003; 17: 2753-64. (Pubitemid 37463285)
-
(2003)
Genes and Development
, vol.17
, Issue.22
, pp. 2753-2764
-
-
Xing, Y.1
Clements, W.K.2
Kimelman, D.3
Xu, W.4
-
63
-
-
33644763022
-
The APC tumor suppressor counteracts β-catenin activation and H3K4 methylation at Wnt target genes
-
DOI 10.1101/gad.1385806
-
Sierra J, Yoshida T, Joazeiro CA, Jones KA,. The APC tumor suppressor counteracts β-catenin activation and H3K4 methylation at Wnt target genes. Genes Dev 2006; 20: 586-600. (Pubitemid 43345324)
-
(2006)
Genes and Development
, vol.20
, Issue.5
, pp. 586-600
-
-
Sierra, J.1
Yoshida, T.2
Joazeiro, C.A.3
Jones, K.A.4
-
65
-
-
0025899162
-
Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients
-
Nishisho I, Nakamura Y, Miyoshi Y, Miki Y, Ando H, Horii A, Koyama K, Utsunomiya J, Baba S, Hedge P,. Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science 1991; 253: 665-9. (Pubitemid 21917200)
-
(1991)
Science
, vol.253
, Issue.5020
, pp. 665-669
-
-
Nishisho, I.1
Nakamura, Y.2
Miyoshi, Y.3
Miki, Y.4
Ando, H.5
Horii, A.6
Koyama, K.7
Utsunomiya, J.8
Baba, S.9
Hedge, P.10
Markham, A.11
Krush, A.J.12
Petersen, G.13
Hamilton, S.R.14
Nilbert, M.C.15
Levy, D.B.16
Bryan, T.M.17
Preisinger, A.C.18
Smith, K.J.19
Su, L.-K.20
Kinzler, K.W.21
Vogelstein, B.22
more..
-
66
-
-
0025817880
-
Identification of FAP locus genes from chromosome 5q21
-
Kinzler KW, Nilbert MC, Su LK, Vogelstein B, Bryan TM, Levy DB, Smith KJ, Preisinger AC, Hedge P, McKechnie D, et al. Identification of FAP locus genes from chromosome 5q21. Science 1991; 253: 661-5. (Pubitemid 21917199)
-
(1991)
Science
, vol.253
, Issue.5020
, pp. 661-665
-
-
Kinzler, K.W.1
Nilbert, M.C.2
Su, L.-K.3
Vogelstein, B.4
Bryan, T.M.5
Levy, D.B.6
Smith, K.J.7
Preisinger, A.C.8
Hedge, P.9
Mckechnie, D.10
Finniear, R.11
Markham, A.12
Groffen, J.13
Boguski, M.S.14
Altschul, S.F.15
Horii, A.16
Ando, H.17
Miyoshi, Y.18
Miki, Y.19
Nishisho, I.20
Nakamura, Y.21
more..
-
68
-
-
85047688110
-
Somatic Mutations in Familial Adenomatous Polyps: Nuclear Translocation of β-Catenin Requires More Than Biallelic APC Inactivation
-
DOI 10.1309/4E4W-G3AY-GJNC-D11P
-
Blaker H, Scholten M, Sutter C, Otto HF, Penzel R,. Somatic mutations in familial adenomatous polyps. Nuclear translocation of β-catenin requires more than biallelic APC inactivation. Am J Clin Pathol 2003; 120: 418-23. (Pubitemid 37295114)
-
(2003)
American Journal of Clinical Pathology
, vol.120
, Issue.3
, pp. 418-423
-
-
Blaker, H.1
Scholten, M.2
Sutter, C.3
Otto, H.F.4
Penzel, R.5
-
69
-
-
65549159598
-
A two step model for colon adenoma initiation and progression caused by APC loss
-
Phelps RA, Chidester S, Dehghanizadeh S, Phelps J, Sandoval IT, Rai K, Broadbent T, Sarkar S, Burt RW, Jones DA,. A two step model for colon adenoma initiation and progression caused by APC loss. Cell 2009; 137: 623-34.
-
(2009)
Cell
, vol.137
, pp. 623-634
-
-
Phelps, R.A.1
Chidester, S.2
Dehghanizadeh, S.3
Phelps, J.4
Sandoval, I.T.5
Rai, K.6
Broadbent, T.7
Sarkar, S.8
Burt, R.W.9
Jones, D.A.10
-
70
-
-
0019026208
-
Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinse
-
Embi N, Rylatt DB, Cohen P,. Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinse. Eur J Biochem 1980; 107: 519-27.
-
(1980)
Eur J Biochem
, vol.107
, pp. 519-527
-
-
Embi, N.1
Rylatt, D.B.2
Cohen, P.3
-
71
-
-
0025286104
-
Molecular cloning and expression of glycogen synthase kinase-3/factor A
-
Woodgett JR,. Molecular cloning and expression of glycogen synthase kinase-3/factor A. EMBO J 1990; 9: 2431-8.
-
(1990)
EMBO J
, vol.9
, pp. 2431-2438
-
-
Woodgett, J.R.1
-
72
-
-
33947597084
-
Glycogen synthase kinase-3 (GSK3): Inflammation, diseases, and therapeutics
-
DOI 10.1007/s11064-006-9128-5
-
Jope RS, Yuskitis CJ, Beurel E,. Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics. Neurochem Res 2007; 32: 577-95. (Pubitemid 46481289)
-
(2007)
Neurochemical Research
, vol.32
, Issue.4-5
, pp. 577-595
-
-
Jope, R.S.1
Yuskaitis, C.J.2
Beurel, E.3
-
73
-
-
33748299477
-
The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways
-
DOI 10.1016/j.pneurobio.2006.07.006, PII S0301008206000797
-
Beurel E, Jope RS,. The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways. Prog Neurobiol 2006; 79: 173-89. (Pubitemid 44331500)
-
(2006)
Progress in Neurobiology
, vol.79
, Issue.4
, pp. 173-189
-
-
Beurel, E.1
Jope, R.S.2
-
74
-
-
68149141502
-
Dynamic telomerase gene suppression via network of GSK3 inhibition
-
Bilsland AE, Hoare S, Stevenson K, Plumb J, Gomez-Roman N, Cairney C, Burns S, Lafferty-Whyte K, Roffey J, Hammonds T, Keith WN,. Dynamic telomerase gene suppression via network of GSK3 inhibition. PLoS One 2009; 4: e6459.
-
(2009)
PLoS One
, vol.4
-
-
Bilsland, A.E.1
Hoare, S.2
Stevenson, K.3
Plumb, J.4
Gomez-Roman, N.5
Cairney, C.6
Burns, S.7
Lafferty-Whyte, K.8
Roffey, J.9
Hammonds, T.10
Keith, W.N.11
-
75
-
-
34249311572
-
Functional Redundancy of GSK-3α and GSK-3β in Wnt/β-Catenin Signaling Shown by Using an Allelic Series of Embryonic Stem Cell Lines
-
DOI 10.1016/j.devcel.2007.04.001, PII S1534580707001487
-
Doble BW, Patel S, Wood GA, Kockeritz LK, Woodgett JR,. Functional redundancy of GSK-3αand GSK-3β in Wnt/β-catenin signaling shown by using and allelic series of embryonic stem cell lines. Dev Cell 2007; 12: 957-71. (Pubitemid 46805920)
-
(2007)
Developmental Cell
, vol.12
, Issue.6
, pp. 957-971
-
-
Doble, B.W.1
Patel, S.2
Wood, G.A.3
Kockeritz, L.K.4
Woodgett, J.R.5
-
76
-
-
60549098654
-
Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity
-
Song S, Mazurek N, Liu C, Sun Y, Ding QQ, Liu K, Hung MC, Bresalier RS,. Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity. Cancer Res 2009; 69: 1343-9.
-
(2009)
Cancer Res
, vol.69
, pp. 1343-1349
-
-
Song, S.1
Mazurek, N.2
Liu, C.3
Sun, Y.4
Ding, Q.Q.5
Liu, K.6
Hung, M.C.7
Bresalier, R.S.8
-
77
-
-
77954757417
-
β-catenin/TCF pathway plays a vital role in selenium induced-growth inhibition and apoptosis in esophageal squamous cell carcinoma (ESCC) cells
-
Zhang W, Yan S, Liu M, Zhang G, Yang S, He S, Bai J, Quan L, Zhu H, Dong Y, Xu N,. β-catenin/TCF pathway plays a vital role in selenium induced-growth inhibition and apoptosis in esophageal squamous cell carcinoma (ESCC) cells. Cancer Lett 2010; 296: 113-22.
-
(2010)
Cancer Lett
, vol.296
, pp. 113-122
-
-
Zhang, W.1
Yan, S.2
Liu, M.3
Zhang, G.4
Yang, S.5
He, S.6
Bai, J.7
Quan, L.8
Zhu, H.9
Dong, Y.10
Xu, N.11
-
78
-
-
58149383852
-
Effect of selenium and vitamin e on risk of prostate cancer and other cancers: The Selenium and Vitamin e Cancer Prevention Trial (SELECT)
-
Lippman SM, Klein EA, Goodman PJ, Lucia MS, Thompson IM, Ford LG, Parnes HL, Minasian LM, Gaziano JM, Hartline JA, Parsons JK, Bearden JD, et al. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA 2009; 301: 39-51.
-
(2009)
JAMA
, vol.301
, pp. 39-51
-
-
Lippman, S.M.1
Klein, E.A.2
Goodman, P.J.3
Lucia, M.S.4
Thompson, I.M.5
Ford, L.G.6
Parnes, H.L.7
Minasian, L.M.8
Gaziano, J.M.9
Hartline, J.A.10
Parsons, J.K.11
Bearden, J.D.12
-
79
-
-
75849133697
-
A phase I/II trial of enzastaurin in patients with recurrent high-grade gliomas
-
Kreisl TN, Kotliarova S, Butman JA, Albert PS, Kim L, Musib L, Thornton D, Fine HA,. A phase I/II trial of enzastaurin in patients with recurrent high-grade gliomas. Neuro Oncol 2010; 12: 181-9.
-
(2010)
Neuro Oncol
, vol.12
, pp. 181-189
-
-
Kreisl, T.N.1
Kotliarova, S.2
Butman, J.A.3
Albert, P.S.4
Kim, L.5
Musib, L.6
Thornton, D.7
Fine, H.A.8
-
80
-
-
61849179573
-
Targeting PKC: A novel role for beta-catenin in ER stress and apoptotic signaling
-
Raab MS, Breitkreutz I, Tonon G, Zhang J, Hayden PJ, Nguyen T, Fruehauf JH, Lin BK, Chauhan D, Hideshima T, Munshi NC, Anderson KC, et al. Targeting PKC: a novel role for beta-catenin in ER stress and apoptotic signaling. Blood 2009; 113: 1513-21.
-
(2009)
Blood
, vol.113
, pp. 1513-1521
-
-
Raab, M.S.1
Breitkreutz, I.2
Tonon, G.3
Zhang, J.4
Hayden, P.J.5
Nguyen, T.6
Fruehauf, J.H.7
Lin, B.K.8
Chauhan, D.9
Hideshima, T.10
Munshi, N.C.11
Anderson, K.C.12
-
81
-
-
0033572974
-
Transient overexpression of murine Dishevelled genes results in apoptotic cell death
-
DOI 10.1006/excr.1999.4700
-
Strovel ET, Sussman DJ,. Transient overexpression of murine Dishevelled genes results in apoptotic cell death. Exp Cell Res 1999; 253: 637-48. (Pubitemid 30003125)
-
(1999)
Experimental Cell Research
, vol.253
, Issue.2
, pp. 637-648
-
-
Strovel, E.T.1
Sussman, D.J.2
-
82
-
-
0032967755
-
Dishevelled: At the crossroads of divergent intracellular signaling pathways
-
DOI 10.1016/S0925-4773(99)00046-5, PII S0925477399000465
-
Boutros M, Mlodzik M,. Dishevelled: at the crossroads of divergent intracellular signaling pathways. Mech Dev 1999; 83: 27-37. (Pubitemid 29302079)
-
(1999)
Mechanisms of Development
, vol.83
, Issue.1-2
, pp. 27-37
-
-
Boutros, M.1
Mlodzik, M.2
-
83
-
-
37549056198
-
Differential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1, -2, and -3
-
Lee YN, Gao Y, Wang HY,. Differential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1, -2, and -3. Cell Signal 2008; 20: 443-52.
-
(2008)
Cell Signal
, vol.20
, pp. 443-452
-
-
Lee, Y.N.1
Gao, Y.2
Wang, H.Y.3
-
84
-
-
67650230896
-
Wnt/β-catenin signaling: Components, mechanisms, and diseases
-
MacDonald BT, Tamai K, He X,. Wnt/β-catenin signaling: components, mechanisms, and diseases. Dev Cell 2009; 17: 9-26.
-
(2009)
Dev Cell
, vol.17
, pp. 9-26
-
-
MacDonald, B.T.1
Tamai, K.2
He, X.3
-
85
-
-
38949194936
-
Initiation of Wnt signaling: Control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions
-
DOI 10.1242/dev.013540
-
Zeng X, Huang H, Tamai K, Zhang X, Harada Y, Yokota C, Almeida K, Wang J, Doble B, Woodgett J, Wynshaw-Boris A, Hsieh JC, et al. Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. Development 2008; 135: 367-75. (Pubitemid 351228428)
-
(2008)
Development
, vol.135
, Issue.2
, pp. 367-375
-
-
Zeng, X.1
Huang, H.2
Tamai, K.3
Zhang, X.4
Harada, Y.5
Yokota, C.6
Almeida, K.7
Wang, J.8
Doble, B.9
Woodgett, J.10
Wynshaw-Boris, A.11
Hsieh, J.-C.12
He, X.13
-
86
-
-
33846354928
-
The RNA-binding protein KSRP promotes decay of β-catenin mRNA and is inactivated by PI3K-AKT signaling
-
Gherzi R, Trabucchi M, Ponassi M, Ruggiero T, Corte G, Moroni C, Chen CY, Khabar KS, Andersen JS, Briata P,. The RNA-binding protein KSRP promotes decay of β-catenin mRNA and is inactivated by PI3K-AKT signaling. PLoS Biol 2006; 5: e5.
-
(2006)
PLoS Biol
, vol.5
-
-
Gherzi, R.1
Trabucchi, M.2
Ponassi, M.3
Ruggiero, T.4
Corte, G.5
Moroni, C.6
Chen, C.Y.7
Khabar, K.S.8
Andersen, J.S.9
Briata, P.10
-
87
-
-
77951180969
-
Dishevelled-KSRP complex regulates Wnt signaling through post-transcriptional stabilization of β-catenin mRNA
-
Bikkavilli RK, Malbon CC,. Dishevelled-KSRP complex regulates Wnt signaling through post-transcriptional stabilization of β-catenin mRNA. J Cell Sci 2010; 123: 1352-62.
-
(2010)
J Cell Sci
, vol.123
, pp. 1352-1362
-
-
Bikkavilli, R.K.1
Malbon, C.C.2
-
88
-
-
77951888466
-
Dishevelled: The hub of Wnt signaling
-
Gao C, Chen YG,. Dishevelled: the hub of Wnt signaling. Cell Signal 2010; 22: 717-27.
-
(2010)
Cell Signal
, vol.22
, pp. 717-727
-
-
Gao, C.1
Chen, Y.G.2
-
89
-
-
41549133557
-
Nuclear Dvl, c-Jun, β-catenin, and TCF form a complex leading to stabilization of β-catenin-TCF interaction
-
DOI 10.1083/jcb.200710050
-
Gan XQ, Wang JY, Xi Y, Wu ZL, Li YP, Li L,. Nuclear Dvl, c-Jun, β-catenin, and TCF form a complex leading to stabilization of β-catenin-TCF interaction. J Cell Biol 2008; 180: 1087-100. (Pubitemid 351468467)
-
(2008)
Journal of Cell Biology
, vol.180
, Issue.6
, pp. 1087-1100
-
-
Gan, X.-Q.1
Wang, J.-Y.2
Xi, Y.3
Wu, Z.-L.4
Li, Y.-P.5
Li, L.6
-
90
-
-
0034755201
-
Global expression changes of constitutive and hormonally regulated genes during endometrial neoplastic transformation
-
DOI 10.1006/gyno.2001.6352
-
Mutter GL, Baak JP, Fitzgerald JT, Gray R, Neuberg D, Kust GA, Gentleman R, Gullans SR, Wei LJ, Wilcox M,. Global expression changes of constitutive and hormonally regulated genes during endometrial neoplastic transformation. Gynecol Oncol 2001; 83: 177-85. (Pubitemid 33033052)
-
(2001)
Gynecologic Oncology
, vol.83
, Issue.2
, pp. 177-185
-
-
Mutter, G.L.1
Baak, J.P.A.2
Fitzgerald, J.T.3
Gray, R.4
Neuberg, D.5
Kust, G.A.6
Gentleman, R.7
Gullans, S.R.8
Wei, L.-J.9
Wilcox, M.10
-
91
-
-
2542565666
-
Gene expression in the urinary bladder: A common carcinoma in situ gene expression signature exists disregarding histopathological classification
-
DOI 10.1158/0008-5472.CAN-03-3620
-
Dyrskjøt L, Kruhøffer M, Thykjaer T, Marcussen N, Jensen JL, Møller K, Ørntoft TF,. Gene expressionin the urinary bladder: a common carcinoma in situ gene expression signature exists disregarding histopathological classification. Cancer Res 2004; 64: 4040-8. (Pubitemid 38697320)
-
(2004)
Cancer Research
, vol.64
, Issue.11
, pp. 4040-4048
-
-
Dyrskjot, L.1
Kruhoffer, M.2
Thykjaer, T.3
Marcussen, N.4
Jensen, J.L.5
Moller, K.6
Orntoft, T.F.7
-
92
-
-
60649114313
-
Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and β-catenin stabilization
-
Wang L, Heidt DG, Lee CJ, Yang H, Logsdon CD, Zhang L, Fearon ER, Ljungman M, Simeone DM,. Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and β-catenin stabilization. Cancer Cell 2009; 15: 207-19.
-
(2009)
Cancer Cell
, vol.15
, pp. 207-219
-
-
Wang, L.1
Heidt, D.G.2
Lee, C.J.3
Yang, H.4
Logsdon, C.D.5
Zhang, L.6
Fearon, E.R.7
Ljungman, M.8
Simeone, D.M.9
-
93
-
-
77649259009
-
Loss of the tumor suppressor CYLD enhances Wnt/β-catenin signaling through K63-linked ubiquitination of Dvl
-
Tauriello DV, Haegebarth A, Kuper I, Edelmann MJ, Henraat M, Canninga-van Dijk MR, Kessler BM, Clevers H, Maurice MM,. Loss of the tumor suppressor CYLD enhances Wnt/β-catenin signaling through K63-linked ubiquitination of Dvl. Mol Cell 2010; 37: 607-19.
-
(2010)
Mol Cell
, vol.37
, pp. 607-619
-
-
Tauriello, D.V.1
Haegebarth, A.2
Kuper, I.3
Edelmann, M.J.4
Henraat, M.5
Canninga-Van Dijk, M.R.6
Kessler, B.M.7
Clevers, H.8
Maurice, M.M.9
-
94
-
-
77954310807
-
Ubiquitin chain cleavage: CYLD at work
-
Massoumi R,. Ubiquitin chain cleavage: CYLD at work. Trends Biochem Sci 2010; 35: 393-9.
-
(2010)
Trends Biochem Sci
, vol.35
, pp. 393-399
-
-
Massoumi, R.1
-
95
-
-
0023926935
-
The cadherins: Cell-cell adhesion molecules controlling animal morphogenesis
-
Takeichi M,. The cadherins: cell-cell adhesion molecules controlling animal morphogenesis. Development 1988; 102: 639-55.
-
(1988)
Development
, vol.102
, pp. 639-655
-
-
Takeichi, M.1
-
96
-
-
0034235891
-
Identification of three human type-II classic cadherins and frequent heterophilic interactions between different subclasses of type-II classic cadherins
-
DOI 10.1042/0264-6021:3490159
-
Shimoyama Y, Tsujimoto G, Kitajima M, Natori M,. Identification of three human type-II classic cadherins and frequent heterophilic interactions between different subclasses of type-II classic cadherins. Biochem J 2000; 349: 159-67. (Pubitemid 30440178)
-
(2000)
Biochemical Journal
, vol.349
, Issue.1
, pp. 159-167
-
-
Shimoyama, Y.1
Tsujimoto, G.2
Kitajima, M.3
Natori, M.4
-
97
-
-
33646030613
-
Type II cadherin ectodomain structures: Implications for classical cadherin specificity
-
Patel SD, Ciatto C, Chen CP, Bahna F, Rajebhosale M, Arkus N, Schieren I, Jessell TM, Honig B, Price SR, Shapiro L,. Type II cadherin ectodomain structures: implications for classical cadherin specificity. Cell 2006; 124: 1255-68.
-
(2006)
Cell
, vol.124
, pp. 1255-1268
-
-
Patel, S.D.1
Ciatto, C.2
Chen, C.P.3
Bahna, F.4
Rajebhosale, M.5
Arkus, N.6
Schieren, I.7
Jessell, T.M.8
Honig, B.9
Price, S.R.10
Shapiro, L.11
-
98
-
-
58549115688
-
Resolving cadherin interactions and binding cooperativity at the single-molecule level
-
Zhang Y, Sivasankar S, Nelson WJ, Chu S,. Resolving cadherin interactions and binding cooperativity at the single-molecule level. Proc Natl Acad Sci USA 2009; 106: 109-14.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 109-114
-
-
Zhang, Y.1
Sivasankar, S.2
Nelson, W.J.3
Chu, S.4
-
99
-
-
28344433073
-
Deconstructing the cadherin-catenin-actin complex
-
DOI 10.1016/j.cell.2005.09.020, PII S0092867405009748
-
Yamada S, Pokutta S, Drees F, Weis WI, Nelson WJ,. Deconstructing the cadherin-catenin-actin complex. Cell 2005; 123: 889-901. (Pubitemid 41721034)
-
(2005)
Cell
, vol.123
, Issue.5
, pp. 889-901
-
-
Yamada, S.1
Pokutta, S.2
Drees, F.3
Weis, W.I.4
Nelson, W.J.5
-
100
-
-
35548932457
-
Structure and mechanism of cadherins and catenins in cell-cell contacts
-
Pokutta S, Weis WI,. Structure and mechanism of cadherins and catenins in cell-cell contacts. Annu Rev Cell Dev Biol 2007; 23: 237-61.
-
(2007)
Annu Rev Cell Dev Biol
, vol.23
, pp. 237-261
-
-
Pokutta, S.1
Weis, W.I.2
-
101
-
-
38349138921
-
EPLIN mediates linkage of the cadherin catenin complex to F-actin and stabilizes the circumferential actin belt
-
Abe K, Takeichi M,. EPLIN mediates linkage of the cadherin catenin complex to F-actin and stabilizes the circumferential actin belt. Proc Natl Acad Sci USA 2008; 105: 13-9.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13-19
-
-
Abe, K.1
Takeichi, M.2
-
102
-
-
77149179101
-
Adherens junction: Molecular architecture and regulation
-
Meng W, Takeichi M,. Adherens junction: molecular architecture and regulation. Cold Spring Harb Perspect Biol 2009; 1: a002899.
-
(2009)
Cold Spring Harb Perspect Biol
, vol.1
-
-
Meng, W.1
Takeichi, M.2
-
103
-
-
56349123945
-
Anchorage of microtubule minus ends to adherens junctions regulates epithelial cell-cell contacts
-
Meng W, Mushika Y., Ichii T, Takeichi M,. Anchorage of microtubule minus ends to adherens junctions regulates epithelial cell-cell contacts. Cell 2008; 135: 948-59.
-
(2008)
Cell
, vol.135
, pp. 948-959
-
-
Meng, W.1
Mushika, Y.2
Ichii, T.3
Takeichi, M.4
-
104
-
-
77950932981
-
Dynamic and static interaction between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion. Dynamic and static interaction between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion
-
Ishiyama N, Lee SH, Liu S, Li GY, Smith MJ, Reichardt LF, Ikura M,. Dynamic and static interaction between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion. Dynamic and static interaction between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion. Cell 2010; 141: 117-28.
-
(2010)
Cell
, vol.141
, pp. 117-128
-
-
Ishiyama, N.1
Lee, S.H.2
Liu, S.3
Li, G.Y.4
Smith, M.J.5
Reichardt, L.F.6
Ikura, M.7
-
105
-
-
0033593803
-
Coupling assembly of the E-cadherin/β-catenin complex to efficient endoplasmic reticulum exit and basal-lateral membrane targeting of E-cadherin in polarized MDCK cells
-
DOI 10.1083/jcb.144.4.687
-
Chen YT, Stewart DB, Nelson WJ,. Coupling assembly of the E-cadherin/beta-catenin complex to efficient endoplasmic reticulum exit and basal-lateral membrane targeting of E-cadherin in polarized MDCK cells. J Cell Biol 1999; 144: 687-99. (Pubitemid 29234547)
-
(1999)
Journal of Cell Biology
, vol.144
, Issue.4
, pp. 687-699
-
-
Chen, Y.-T.1
Stewart, D.B.2
Nelson, W.J.3
-
106
-
-
0035933872
-
A dileucine motif targets E-cadherin to the basolateral cell surface in Madin-Darby canine kidney and LLC-PK1 epithelial cells
-
Miranda KC, Khromykh T, Christy P, Le TL, Gottardi CJ, Yap AS, Stow JL, Teasdale RD,. A dileucine motif targets E-cadherin to the basolateral cell surface in Madin-Darby canine kidney and LLC-PK1 epithelial cells. J Biol Chem 2001; 276: 22565-72.
-
(2001)
J Biol Chem
, vol.276
, pp. 22565-22572
-
-
Miranda, K.C.1
Khromykh, T.2
Christy, P.3
Le, T.L.4
Gottardi, C.J.5
Yap, A.S.6
Stow, J.L.7
Teasdale, R.D.8
-
108
-
-
76649113736
-
Vinculin regulates cell-surface E-cadherin expression by binding to β-catenin
-
Peng X, Cuff LE, Lawton CD, DeMali K,. Vinculin regulates cell-surface E-cadherin expression by binding to β-catenin. J Cell Sci 2010; 123 (Pt4): 567-77.
-
(2010)
J Cell Sci
, vol.123
, Issue.PART 4
, pp. 567-577
-
-
Peng, X.1
Cuff, L.E.2
Lawton, C.D.3
Demali, K.4
-
109
-
-
77149149725
-
Junctional music that the nucleus hears: Cell-cell contact signaling and the modulation of gene activity
-
McCrea PD, Gu D, Balda MS,. Junctional music that the nucleus hears: cell-cell contact signaling and the modulation of gene activity. Cold Spring Harb Perspect Biol 2009; 1: a002923.
-
(2009)
Cold Spring Harb Perspect Biol
, vol.1
-
-
McCrea, P.D.1
Gu, D.2
Balda, M.S.3
-
110
-
-
34249661591
-
Phosphorylation of β-catenin by AKT promotes β-catenin transcriptional activity
-
DOI 10.1074/jbc.M611871200
-
Fang D, Hawke D, Zheng Y, Xia Y, Meisenhelder J, Nika H, Mills GB, Kobayashi R, Hunter T, Lu Z,. Phosphorylation of β-catenin by AKT promotes β-catenin transcriptional activity. J Biol Chem 2007; 282: 11221-9. (Pubitemid 47100795)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.15
, pp. 11221-11229
-
-
Fang, D.1
Hawke, D.2
Zheng, Y.3
Xia, Y.4
Meisenhelder, J.5
Nika, H.6
Mills, G.B.7
Kobayashi, R.8
Hunter, T.9
Lu, Z.10
-
111
-
-
41949105179
-
Rac1 Activation Controls Nuclear Localization of β-catenin during Canonical Wnt Signaling
-
DOI 10.1016/j.cell.2008.01.052, PII S0092867408002791
-
Wu X M, Tu XL, Joeng K S, Hilton M J, Williams DA, Long F,. Rac1 activation controls nuclear localization of β-catenin during canonical Wnt signaling. Cell 2008; 133: 340-53. (Pubitemid 351508298)
-
(2008)
Cell
, vol.133
, Issue.2
, pp. 340-353
-
-
Wu, X.1
Tu, X.2
Joeng, K.S.3
Hilton, M.J.4
Williams, D.A.5
Long, F.6
-
112
-
-
0035827543
-
Regulation of β-catenin structure and activity by tyrosine phosphorylation
-
Piedra J, Martinez D, Castano J, Miravet S, Dunach M, de Herreros AG,. Regulation of β-catenin structure and activity by tyrosine phosphorylation. J Biol Chem 2001; 276: 20436-43.
-
(2001)
J Biol Chem
, vol.276
, pp. 20436-20443
-
-
Piedra, J.1
Martinez, D.2
Castano, J.3
Miravet, S.4
Dunach, M.5
De Herreros, A.G.6
-
113
-
-
0033579480
-
Regulation of E-cadherin/catenin association by tyrosine phosphorylation
-
Roura S, Miravet S, Piedra J, García de Herreros A, Duñach M,. Regulation of E-cadherin/catenin association by tyrosine phosphorylation. J Biol Chem 1999; 274: 36734-40.
-
(1999)
J Biol Chem
, vol.274
, pp. 36734-36740
-
-
Roura, S.1
Miravet, S.2
Piedra, J.3
García De Herreros, A.4
Duñach, M.5
-
114
-
-
79960902982
-
Efficacy and safety of bosutinib (SKI-606) among patients with chronic phase Ph+ chronic myelogenous leukemia (CML)
-
(abstr:733)
-
Jorge C, Kantarjian HM, Kim DW, Khoury HJ, Turkina AG, Shen ZX, Brummendorf TH, Chandy M, Arkin S, Gambacorti-Passerini C,. Efficacy and safety of bosutinib (SKI-606) among patients with chronic phase Ph+ chronic myelogenous leukemia (CML). Blood 2007; 110:(abstr:733).
-
(2007)
Blood
, vol.110
-
-
Jorge, C.1
Kantarjian, H.M.2
Kim, D.W.3
Khoury, H.J.4
Turkina, A.G.5
Shen, Z.X.6
Brummendorf, T.H.7
Chandy, M.8
Arkin, S.9
Gambacorti-Passerini, C.10
-
115
-
-
54249151670
-
Bosutinib is safe and active in patients (pts) with chronic phase (CP) chronic myeloid leukemia (CML) with resistance or intolerance to imatinib and other tyrosine kinase inhibitors
-
(abstr 7001)
-
Bruemmendorf TH, Cervantes F, Kim D, Chandy M, Fischer T, Hochhaus A, Liu D, Ossenkoppele GJ, Hewes B, Cortes JE,. Bosutinib is safe and active in patients (pts) with chronic phase (CP) chronic myeloid leukemia (CML) with resistance or intolerance to imatinib and other tyrosine kinase inhibitors. J Clin Oncol 2008; 26:(abstr 7001).
-
(2008)
J Clin Oncol
, vol.26
-
-
Bruemmendorf, T.H.1
Cervantes, F.2
Kim, D.3
Chandy, M.4
Fischer, T.5
Hochhaus, A.6
Liu, D.7
Ossenkoppele, G.J.8
Hewes, B.9
Cortes, J.E.10
-
116
-
-
77956042544
-
SRC: A century of science brought to the clinic
-
Aleshin A, Finn RS,. SRC: a century of science brought to the clinic. Neoplasia 2010; 12: 599-607.
-
(2010)
Neoplasia
, vol.12
, pp. 599-607
-
-
Aleshin, A.1
Finn, R.S.2
-
117
-
-
77957826313
-
Locking Src/Abl tyrosine kinase activities regulate cell differentiation and invasion of human cervical cancer cells expressing E6/E7 oncoproteins of high-risk HPV
-
Yasmeen A, Alachkar A, Dekhil H, Gambacorti-Passerini C, Al Moustafa AE,. Locking Src/Abl tyrosine kinase activities regulate cell differentiation and invasion of human cervical cancer cells expressing E6/E7 oncoproteins of high-risk HPV. J Oncol 2010; 2010: 530130.
-
(2010)
J Oncol
, vol.2010
, pp. 530130
-
-
Yasmeen, A.1
Alachkar, A.2
Dekhil, H.3
Gambacorti-Passerini, C.4
Al Moustafa, A.E.5
-
118
-
-
7244229604
-
Distinct molecular forms of β-catenin are targeted to adhesive or transcriptional complexes
-
DOI 10.1083/jcb.200402153
-
Gottardi CJ, Gumbiner BM,. Distinct molecular forms of β-catenin are targeted to adhesive or transcriptional complexes. J Cell Biol 2004; 167: 339-49. (Pubitemid 39435076)
-
(2004)
Journal of Cell Biology
, vol.167
, Issue.2
, pp. 339-349
-
-
Gottardi, C.J.1
Gumbiner, B.M.2
-
119
-
-
77956300964
-
β-catenin phosphorylated at serine 45 is spatially uncoupled from β-catenin phosphorylated in the GSK3 domain: Implications for signaling
-
Maher MT, Mo R, Flozak AS, Peled ON, Gottardi CJ,. β-catenin phosphorylated at serine 45 is spatially uncoupled from β-catenin phosphorylated in the GSK3 domain: implications for signaling, PLoS One 2010; 5: e10184.
-
(2010)
PLoS One
, vol.5
-
-
Maher, M.T.1
Mo, R.2
Flozak, A.S.3
Peled, O.N.4
Gottardi, C.J.5
-
120
-
-
67749120363
-
Activity of the β-catenin phosphodestruction complex at cell-cell contacts is enhanced by cadherin-based adhesion
-
Maher MT, Flozak AS, Stocker AM, Chenn A, Gottardi CJ,. Activity of the β-catenin phosphodestruction complex at cell-cell contacts is enhanced by cadherin-based adhesion. J Cell Biol 2009; 186: 219-28.
-
(2009)
J Cell Biol
, vol.186
, pp. 219-228
-
-
Maher, M.T.1
Flozak, A.S.2
Stocker, A.M.3
Chenn, A.4
Gottardi, C.J.5
-
121
-
-
59449095748
-
N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/β-catenin signaling, osteoblast function, and bone formation
-
Haà E, Laplantine E, Geoffroy V, Frain M, Kohler T, Müller R, Marie PJ,. N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/β-catenin signaling, osteoblast function, and bone formation. Mol Cell Biol 2009; 29: 953-64.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 953-964
-
-
Haã, E.1
Laplantine, E.2
Geoffroy, V.3
Frain, M.4
Kohler, T.5
Müller, R.6
Marie, P.J.7
-
122
-
-
77957195392
-
Exosome release of β-catenin: A novel mechanism that antagonizes Wnt signaling
-
Chairoungdua A, Smith DL, Pochard P, Hull M, Caplan MJ,. Exosome release of β-catenin: a novel mechanism that antagonizes Wnt signaling. J Cell Biol 2010; 190: 1079-91.
-
(2010)
J Cell Biol
, vol.190
, pp. 1079-1091
-
-
Chairoungdua, A.1
Smith, D.L.2
Pochard, P.3
Hull, M.4
Caplan, M.J.5
-
123
-
-
67650996280
-
Epithelial-mesenchymal transitions: The importance of changing cell state in development and disease
-
Acloque H, Adams MS, Fishwick K, Bronner-Fraser M, Nieto MA,. Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease. J Clin Invest 2009; 119: 1438-49.
-
(2009)
J Clin Invest
, vol.119
, pp. 1438-1449
-
-
Acloque, H.1
Adams, M.S.2
Fishwick, K.3
Bronner-Fraser, M.4
Nieto, M.A.5
-
124
-
-
77954860342
-
Epithelial-mesenchymal transition in cancer: Parallels between normal development and tumor progression
-
Micalizzi DS, Farabaugh SM, Ford HL,. Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression. J Mammary Gland Biol Neoplasia 2010; 15: 117-34.
-
(2010)
J Mammary Gland Biol Neoplasia
, vol.15
, pp. 117-134
-
-
Micalizzi, D.S.1
Farabaugh, S.M.2
Ford, H.L.3
-
125
-
-
44449144396
-
Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis
-
DOI 10.1016/j.devcel.2008.05.009, PII S1534580708002098
-
Yang J, Weinberg RA,. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell 2008; 14: 818-29. (Pubitemid 351757205)
-
(2008)
Developmental Cell
, vol.14
, Issue.6
, pp. 818-829
-
-
Yang, J.1
Weinberg, R.A.2
-
126
-
-
0242413065
-
Mechanisms, mechanics and function of epithelial-mesenchymal transitions in early development
-
DOI 10.1016/j.mod.2003.06.005
-
Shook D, Keller R,. Mechanisms, mechanics and function of epithelial-mesenchymal transitions in early development. Mech Dev 2003; 120: 1351-83. (Pubitemid 37421168)
-
(2003)
Mechanisms of Development
, vol.120
, Issue.11
, pp. 1351-1383
-
-
Shook, D.1
Keller, R.2
-
127
-
-
0043172396
-
Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis
-
DOI 10.1038/nrm1175
-
Grünert S, Jechlinger M, Beug H,. Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis. Proc Natl Acad Sci USA 2003; 4: 657-65. (Pubitemid 36934968)
-
(2003)
Nature Reviews Molecular Cell Biology
, vol.4
, Issue.8
, pp. 657-665
-
-
Grunert, S.1
Jechlinger, M.2
Beug, H.3
-
128
-
-
27844461512
-
Epithelial-mesenchymal transition in development and cancer: Role of phosphatidylinositol 3′ kinase/AKT pathways
-
DOI 10.1038/sj.onc.1209091, PII 1209091
-
Larue L, Bellacosa A,. Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3′ kinase/AKT pathways. Oncogene 2005; 24: 7443-54. (Pubitemid 41637984)
-
(2005)
Oncogene
, vol.24
, Issue.50
, pp. 7443-7454
-
-
Larue, L.1
Bellacosa, A.2
-
129
-
-
77954304397
-
Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition
-
Chao Y.L, Shepard CR, Wells A,. Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition. Mol Cancer 2010; 9: 179.
-
(2010)
Mol Cancer
, vol.9
, pp. 179
-
-
Chao, Y.L.1
Shepard, C.R.2
Wells, A.3
-
130
-
-
61849112651
-
Inhibition of Akt activity induces the mesenchymal-to-epithelial reverting transition with restoring E-cadherin expression in KB and KOSCC-25B oral squamous cell carcinoma cells
-
Hong KO, Kim JH, Hong JS, Yoon HJ, Lee JI, Hong SP, Hong SD,. Inhibition of Akt activity induces the mesenchymal-to-epithelial reverting transition with restoring E-cadherin expression in KB and KOSCC-25B oral squamous cell carcinoma cells. J Exp Clin Cancer Res 2009; 28: 28.
-
(2009)
J Exp Clin Cancer Res
, vol.28
, pp. 28
-
-
Hong, K.O.1
Kim, J.H.2
Hong, J.S.3
Yoon, H.J.4
Lee, J.I.5
Hong, S.P.6
Hong, S.D.7
-
131
-
-
47549098263
-
E-cadherin as an indicator of mesenchymal to epithelial reverting transitions during the metastatic seeding of disseminated carcinomas
-
Wells A, Yates C, Shepard CR,. E-cadherin as an indicator of mesenchymal to epithelial reverting transitions during the metastatic seeding of disseminated carcinomas. Clin Exp Metastasis 2008; 25: 621-8.
-
(2008)
Clin Exp Metastasis
, vol.25
, pp. 621-628
-
-
Wells, A.1
Yates, C.2
Shepard, C.R.3
-
132
-
-
41549162752
-
Transitions between epithelial and mesenchymal states in development and disease
-
Baum B, Settleman J, Quinlan MP,. Transitions between epithelial and mesenchymal states in development and disease. Semin Cell Dev Biol 2008; 19: 294-308.
-
(2008)
Semin Cell Dev Biol
, vol.19
, pp. 294-308
-
-
Baum, B.1
Settleman, J.2
Quinlan, M.P.3
-
133
-
-
34250361104
-
E-cadherin homophilic ligation inhibits cell growth and epidermal growth factor receptor signaling independently of other cell interactions
-
DOI 10.1091/mbc.E06-04-0348
-
Perrais M, Chen X, Perez-Moreno M, Gumbiner BM,. E-cadherin homophilic ligation inhibits cell growth and epidermal growth factor receptor signaling independently of other cell interactions. Mol Biol Cell 2007; 18: 2013-25. (Pubitemid 46911354)
-
(2007)
Molecular Biology of the Cell
, vol.18
, Issue.6
, pp. 2013-2025
-
-
Perrais, M.1
Chen, X.2
Perez-Moreno, M.3
Gumbiner, B.M.4
-
134
-
-
34047159398
-
Novel Three-Dimensional Organotypic Liver Bioreactor to Directly Visualize Early Events in Metastatic Progression
-
DOI 10.1016/S0065-230X(06)97010-9, PII S0065230X06970109
-
Yates C, Shepard CR, Papworth G, Dash A, Beer Stolz D, Tannenbaum S, Griffith L, Wells A,. Novel three-dimensional organotypic liver bioreactor to directly visualize early events in metastatic progression. Adv Cancer Res 2007; 97: 225-46. (Pubitemid 46528990)
-
(2007)
Advances in Cancer Research
, vol.97
, pp. 225-246
-
-
Yates, C.1
Shepard, C.R.2
Papworth, G.3
Dash, A.4
Beer Stolz, D.5
Tannenbaum, S.6
Griffith, L.7
Wells, A.8
-
135
-
-
34247217230
-
Co-culturing human prostate carcinoma cells with hepatocytes leads to increased expression of E-cadherin
-
DOI 10.1038/sj.bjc.6603700, PII 6603700
-
Yates CC, Shepard CR, Stolz DB, Wells A,. Co-culturing human prostate carcinoma cells with hepatocytes leads to increased expression of E-cadherin. Br J Cancer 2007; 96: 1246-52. (Pubitemid 46625074)
-
(2007)
British Journal of Cancer
, vol.96
, Issue.8
, pp. 1246-1252
-
-
Yates, C.C.1
Shepard, C.R.2
Stolz, D.B.3
Wells, A.4
-
136
-
-
0037326569
-
The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: A comparison with Snail and E47 repressors
-
DOI 10.1242/jcs.00224
-
Bolõs V, Peinado H, Pérez-Moreno MA, Fraga MF, Esteller M, Cano A,. The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors. J Cell Sci 2003; 116 (Pt 3): 499-511. (Pubitemid 36231290)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.3
, pp. 499-511
-
-
Bolos, V.1
Peinado, H.2
Perez-Moreno, M.A.3
Fraga, M.F.4
Esteller, M.5
Cano, A.6
-
137
-
-
0037086277
-
The SLUG zinc-finger protein represses E-cadherin in breast cancer
-
Hajra KM, Chen DY, Fearon ER,. The SLUG zinc-finger protein represses E-cadherin in breast cancer. Cancer Res 2002; 62: 1613-8. (Pubitemid 34408479)
-
(2002)
Cancer Research
, vol.62
, Issue.6
, pp. 1613-1618
-
-
Hajra, K.M.1
David, Y.-S.C.2
Fearon, E.R.3
-
138
-
-
77249104533
-
Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis
-
Xie D, Gore C, Liu J, Pong RC, Mason R, Hao G, Long M, Kabbani W, Yu L, Zhang H, Chen H, Sun X, et al. Role of DAB2IP in modulating epithelial-to- mesenchymal transition and prostate cancer metastasis. Proc Natl Acad Sci USA 2010; 107: 2485-90.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 2485-2490
-
-
Xie, D.1
Gore, C.2
Liu, J.3
Pong, R.C.4
Mason, R.5
Hao, G.6
Long, M.7
Kabbani, W.8
Yu, L.9
Zhang, H.10
Chen, H.11
Sun, X.12
-
139
-
-
22344435816
-
Epidermal growth factor receptor: A novel target of the Wnt/β-catenin pathway in liver
-
DOI 10.1053/j.gastro.2005.04.013, PII S0016508505006967
-
Tan X, Apte U, Micsenyi A, Kotsagrelos E, Luo JH, Ranganathan S, Monga DK, Bell A, Michalopoulos GK, Monga SP,. Epidermal growth factor receptor: a novel target of the Wnt/beta-catenin pathway in liver. Gastroenterology 2005; 129: 285-302. (Pubitemid 41002061)
-
(2005)
Gastroenterology
, vol.129
, Issue.1
, pp. 285-302
-
-
Tan, X.1
Apte, U.2
Micsenyi, A.3
Kotsagrelos, E.4
Luo, J.-H.5
Ranganathan, S.6
Monga, D.K.7
Bell, A.8
Michalopoulos, G.K.9
Monga, S.P.S.10
-
140
-
-
13944263215
-
TGF-;beta; targets the Wnt pathway components, APC and β-catenin, as Mv1Lu cells undergo cell cycle arrest
-
Satterwhite DJ, Neufeld KL,. TGF-beta targets the Wnt pathway components, APC and beta-catenin, as Mv1Lu cells undergo cell cycle arrest. Cell Cycle 2004; 3: 1069-73. (Pubitemid 40268667)
-
(2004)
Cell Cycle
, vol.3
, Issue.8
, pp. 1069-1073
-
-
Satterwhite, D.J.1
Neufeld, K.L.2
-
141
-
-
15744374449
-
Wnt-dependent regulation of the E-cadherin repressor snail
-
DOI 10.1074/jbc.M413878200
-
Yook JI, Li XY, Ota I, Fearon ER, Weiss SJ,. Wnt-dependent regulation of the E-cadherin repressor snail. J Biol Chem 2005; 280: 11740-8. (Pubitemid 40418488)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.12
, pp. 11740-11748
-
-
Jong, I.Y.1
Li, X.-Y.2
Ota, I.3
Fearon, E.R.4
Weiss, S.J.5
-
142
-
-
50649103964
-
Snail promotes Wnt target gene expression and interacts with beta-catenin
-
Stemmer V, de Craene B, Berx G, Behrens J,. Snail promotes Wnt target gene expression and interacts with beta-catenin. Oncogene 2008; 27: 5075-80.
-
(2008)
Oncogene
, vol.27
, pp. 5075-5080
-
-
Stemmer, V.1
De Craene, B.2
Berx, G.3
Behrens, J.4
-
143
-
-
47549089080
-
Matrix metalloproteinases stimulate epithelial-mesenchymal transition during tumor development
-
Orlichenko LS, Radisky DC,. Matrix metalloproteinases stimulate epithelial-mesenchymal transition during tumor development. Clin Exp Metastasis 2008; 25: 593-600.
-
(2008)
Clin Exp Metastasis
, vol.25
, pp. 593-600
-
-
Orlichenko, L.S.1
Radisky, D.C.2
-
144
-
-
21844432918
-
Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability
-
DOI 10.1038/nature03688
-
Radisky DC, Levy DD, Littlepage LE, Liu H, Nelson CM, Fata JE, Leake D, Godden EL, Albertson DG, Nieto MA, Werb Z, Bissell MJ,. Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability. Nature 2005; 436: 123-7. (Pubitemid 40966197)
-
(2005)
Nature
, vol.436
, Issue.7047
, pp. 123-127
-
-
Radisky, D.C.1
Levy, D.D.2
Littlepage, L.E.3
Liu, H.4
Nelson, C.M.5
Fata, J.E.6
Leake, D.7
Godden, E.L.8
Albertson, D.G.9
Nieto, M.A.10
Werb, Z.11
Bissell, M.J.12
|