Activity of the β-catenin phosphodestruction complex at cell-cell contacts is enhanced by cadherin-based adhesion

Journal of Cell Biology

Volumn 186, Issue 2, 2009, Pages 219-228

  Maher, Meghan T ^a   Flozak, Annette S ^a   Stocker, Adam M ^a   Chenn, Anjen ^a   Gottardi, Cara J ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; APC2 PROTEIN; AXIN; BETA CATENIN; CADHERIN; GLUTATHIONE S TRANSFERASE 3BETA; GLUTATHIONE TRANSFERASE; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL ADHESION; CELL COMMUNICATION; CELL FATE; CONTROLLED STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN PHOSPHODESTRUCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT;

ANIMALS; BETA CATENIN; CADHERINS; CELL ADHESION; CELLS, CULTURED; CYTOSKELETAL PROTEINS; GLYCOGEN SYNTHASE KINASE 3; HUMANS; INTERCELLULAR JUNCTIONS; KERATINOCYTES; MALE; MULTIPROTEIN COMPLEXES; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TCF TRANSCRIPTION FACTORS; WNT PROTEINS;

EID: 67749120363     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200811108     Document Type: Article

References (36)

1. Cong, F., and H. Varmus. 2004. Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-catenin. Proc. Natl. Acad. Sci. USA. 101:2882-2887.
2. Corbit, K.C., A.E. Shyer, W.E. Dowdle, J. Gaulden, V. Singla, M.H. Chen, P.T. Chuang, and J.F. Reiter. 2008. Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms. Nat. Cell Biol. 10:70-76.
3. Cox, R.T., C. Kirkpatrick, and M. Peifer. 1996. Armadillo is required for adherens junction assembly, cell polarity, and morphogenesis during Drosophila embryogenesis. J. Cell Biol. 134:133-148.
4. Dajani, R., E. Fraser, S.M. Roe, M. Yeo, V.M. Good, V. Thompson, T.C. Dale, and L.H. Pearl. 2003. Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex. EMBO J. 22:494-501.
5. Dobbs, L.G., R. Gonzalez, and M.C. Williams. 1986. An improved method for isolating type II cells in high yield and purity. Am. Rev. Respir. Dis. 134:141-145.
6. Dorsky, R.I., L.C. Sheldahl, and R.T. Moon. 2002. A transgenic Lef1/beta-catenin-dependent reporter is expressed in spatially restricted domains throughout zebrafish development. Dev. Biol. 241:229-237.
7. Fagotto, F., N. Funayama, U. Gluck, and B.M. Gumbiner. 1996. Binding to cadherins antagonizes the signaling activity of beta-catenin during axis formation in Xenopus. J. Cell Biol. 132:1105-1114.
8. Fagotto, F., E. Jho, L. Zeng, T. Kurth, T. Joos, C. Kaufmann, and F. Costantini. 1999. Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization. J. Cell Biol. 145:741-756.
9. Gottardi, C.J., and B.M. Gumbiner. 2004a. Distinct molecular forms of β-catenin are targeted to adhesive or transcriptional complexes. J. Cell Biol. 167:339-349.
10. Gottardi, C.J., and B.M. Gumbiner. 2004b. Role for ICAT in beta-catenin-dependent nuclear signaling and cadherin functions. Am. J. Physiol. Cell Physiol. 286:C747-C756.
11. Gottardi, C.J., E. Wong, and B.M. Gumbiner. 2001. E-cadherin suppresses cellular transformation by inhibiting β-catenin signaling in an adhesion-independent manner. J. Cell Biol. 153:1049-1060.
12. Greaves, S., B. Sanson, P. White, and J.P. Vincent. 1999. A screen for identifying genes interacting with armadillo, the Drosophila homolog of beta-catenin. Genetics. 153:1753-1766.
13. Guger, K.A., and B.M. Gumbiner. 2000. A mode of regulation of beta-catenin signaling activity in Xenopus embryos independent of its levels. Dev. Biol. 223:441-448.
14. Ha, N.C., T. Tonozuka, J.L. Stamos, H.J. Choi, and W.I. Weis. 2004. Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation. Mol. Cell. 15:511-521.
15. Halbert, C.L., G.W. Demers, and D.A. Galloway. 1992. The E6 and E7 genes of human papillomavirus type 6 have weak immortalizing activity in human epithelial cells. J. Virol. 66:2125-2134.
16. Hart, M., J.P. Concordet, I. Lassot, I. Albert, R. del los Santos, H. Durand, C. Perret, B. Rubinfeld, F. Margottin, R. Benarous, and P. Polakis. 1999. The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell. Curr. Biol. 9:207-210.
17. Heasman, J., A. Crawford, K. Goldstone, P. Garner-Hamrick, B. Gumbiner, P. McCrea, C. Kintner, C.Y. Noro, and C. Wylie. 1994. Overexpression of cadherins and underexpression of beta-catenin inhibit dorsal mesoderm induction in early Xenopus embryos. Cell. 79:791-803.
18. Henderson, B.R. 2000. Nuclear-cytoplasmic shuttling of APC regulates betacatenin subcellular localization and turnover. Nat. Cell Biol. 2:653-660.
19. Jarrett, C.R., J. Blancato, T. Cao, D.S. Bressette, M. Cepeda, P.E. Young, C.R. King, and S.W. Byers. 2001. Human APC2 localization and allelic imbalance. Cancer Res. 61:7978-7984.
20. Klaus, A., and W. Birchmeier. 2008. Wnt signalling and its impact on development and cancer. Nat. Rev. Cancer. 8:387-398.
21. Liu, C., Y. Li, M. Semenov, C. Han, G.H. Baeg, Y. Tan, Z. Zhang, X. Lin, and X. He. 2002. Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism. Cell. 108:837-847.
22. McCartney, B.M., H.A. Dierick, C. Kirkpatrick, M.M. Moline, A. Baas, M. Peifer, and A. Bejsovec. 1999. Drosophila APC2 is a cytoskeletally- associated protein that regulates wingless signaling in the embryonic epidermis. J. Cell Biol. 146:1303-1318.
23. McCrea, P.D., and B.M. Gumbiner. 1991. Purification of a 92-kDa cytoplasmic protein tightly associated with the cell-cell adhesion molecule E-cadherin (uvomorulin). Characterization and extractability of the protein complex from the cell cytostructure. J. Biol. Chem. 266:4514-4520.
24. Nigam, S.K., E. Rodriguez-Boulan, and R.B. Silver. 1992. Changes in intracellular calcium during the development of epithelial polarity and junctions. Proc. Natl. Acad. Sci. USA. 89:6162-6166.
25. Polakis, P. 2000. Wnt signaling and cancer. Genes Dev. 14:1837-1851.
26. Reinacher-Schick, A., and B.M. Gumbiner. 2001. Apical membrane localization of the adenomatous polyposis coli tumor suppressor protein and subcellular distribution of the β-catenin destruction complex in polarized epithelial cells. J. Cell Biol. 152:491-502.
27. Schwarz-Romond, T., C. Asbrand, J. Bakkers, M. Kuhl, H.J. Schaeffer, J. Huelsken, J. Behrens, M. Hammerschmidt, and W. Birchmeier. 2002. The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling. Genes Dev. 16:2073-2084.
28. Staal, F.J., M. Noort Mv, G.J. Strous, and H.C. Clevers. 2002. Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin. EMBO Rep. 3:63-68.
29. van Es, J.H., C. Kirkpatrick, M. van de Wetering, M. Molenaar, A. Miles, J. Kuipers, O. Destree, M. Peifer, and H. Clevers. 1999. Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor. Curr. Biol. 9:105-108.
30. van Noort, M., J. Meeldijk, R. van der Zee, O. Destree, and H. Clevers. 2002. Wnt signaling controls the phosphorylation status of beta-catenin. J. Biol. Chem. 277:17901-17905.
31. Watt, F.M., D.L. Mattey, and D.R. Garrod. 1984. Calcium-induced reorganization of desmosomal components in cultured human keratinocytes. J. Cell Biol. 99:2211-2215.
32. Willert, K., and K.A. Jones. 2006. Wnt signaling: is the party in the nucleus? Genes Dev. 20:1394-1404.
33. Woodhead, G.J., C.A. Mutch, E.C. Olson, and A. Chenn. 2006. Cell-autonomous beta-catenin signaling regulates cortical precursor proliferation. J. Neurosci. 26:12620-12630.
34. Yamashita, Y.M., D.L. Jones, and M.T. Fuller. 2003. Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome. Science. 301:1547-1550.
35. Yu, X., and M. Bienz. 1999. Ubiquitous expression of a Drosophila adenomatous polyposis coli homolog and its localization in cortical actin caps. Mech. Dev. 84:69-73.
36. Yu, X., L. Waltzer, and M. Bienz. 1999. A new Drosophila APC homologue associated with adhesive zones of epithelial cells. Nat. Cell Biol. 1:144-151.