Cdk5 is essential for soluble amyloid β-Induced degradation of GKAP and remodeling of the synaptic actin cytoskeleton

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Roselli, Francesco ^a,b,c   Livrea, Paolo ^b   Almeida, Osborne F X ^a  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^b UNIVERSITY OF BARI   (Italy)

^c FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; AMYLOID BETA PROTEIN; CYCLIN DEPENDENT KINASE 5; MEMBRANE PROTEIN; PROTEIN GKAP; UNCLASSIFIED DRUG; CALCIUM CHANNEL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NERVE PROTEIN; PROTEASOME; SAPAP1 PROTEIN, RAT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; DOWN REGULATION; FRONTAL CORTEX; GENE CLUSTER; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; NONHUMAN; PALMITOYLATION; POSTSYNAPTIC DENSITY; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION; SYNAPSE; UBIQUITINATION; ACTIN FILAMENT; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME IMMUNOASSAY; GENETICS; METABOLISM; MUTATION; NERVE CELL; NEUROBLASTOMA; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS; SYNAPTOSOME; WISTAR RAT;

RATTUS;

ACTIN CYTOSKELETON; ACTINS; AMYLOID BETA-PEPTIDES; ANIMALS; CALCIUM CHANNELS; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE 5; HUMANS; IMMUNOENZYME TECHNIQUES; MUTAGENESIS, SITE-DIRECTED; MUTATION; NERVE TISSUE PROTEINS; NEUROBLASTOMA; NEURONS; PHOSPHORYLATION; POST-SYNAPTIC DENSITY; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPSES; SYNAPTOSOMES;

EID: 79960894797     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023097     Document Type: Article

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