Stimulation of non-amyloidogenic processing of amyloid-β protein precursor by cryptotanshinone involves activation and translocation of ADAM10 and PKC-α

Journal of Alzheimer's Disease

Volumn 25, Issue 2, 2011, Pages 245-262

  Durairajan, Siva Sundara Kumar ^a   Liu, Liang Feng ^a   Lu, Jia Hong ^a   Koo, Irene ^a   Maruyama, Kei ^b   Chung, Sookja K ^c   Huang, Jian Dong ^c   Li, Min ^a  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^b SAITAMA MEDICAL UNIVERSITY   (Japan)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

ADAM10; Alzheimer's disease; amyloid ; Chinese medicine; cryptotanshinone; neuroblastoma; PKC

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; ADAM10 ENDOPEPTIDASE; ALPHA SECRETASE; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; CRYPTOTANSHINONE; PROTEIN KINASE C ALPHA;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN TRANSPORT; REGULATORY MECHANISM;

EID: 79960706730     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2011-102085     Document Type: Article

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