Salvianolic acid B inhibits Aβ fibril formation and disaggregates preformed fibrils and protects against Aβ-induced cytotoxicty

Neurochemistry International

Volumn 52, Issue 4-5, 2008, Pages 741-750

  Durairajan, Siva Sundara Kumar ^a   Yuan, Qiuju ^b   Xie, Lixia ^a   Chan, Wing Sai ^a   Kum, Wan Fung ^a   Koo, Irene ^a   Liu, Chenli ^b   Song, Youqiang ^b   Huang, Jian Dong ^b   Klein, William L ^c   Li, Min ^a  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Amyloid fibrils; A aggregating ELISA; Alzheimer's disease; Circular dichroism spectroscopy; Cytotoxicity; Electron microscopy; Salvianolic acid B; Thioflavine T

Indexed keywords

AMYLOID BETA PROTEIN; FERULIC ACID; SALVIANOLIC ACID B; THIOFLAVINE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; CYTOTOXICITY; DRUG INHIBITION; DRUG STRUCTURE; NEUROBLASTOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; RAT; SALVIA MILTIORRHIZA;

AMYLOID BETA-PROTEIN; ANTIOXIDANTS; BENZOFURANS; CELL AGGREGATION; CELL LINE, TUMOR; CIRCULAR DICHROISM; DATA INTERPRETATION, STATISTICAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; MICROFIBRILS; MICROSCOPY, ELECTRON; TETRAZOLIUM SALTS; THIAZOLES;

ANIMALIA; RATTUS; SALVIA MILTIORRHIZA;

EID: 38349160407     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2007.09.006     Document Type: Article

References (36)

1. Braun L., Mok V., and Cheung K.K.S. Phase I clinical trial of curcumin for Alzheimer's disease in Chinese Communities. World Congress on Ageing & Dementia in Chinese Communities (2007) 1
2. Butterfield D., Castegna A., Pocernich C., Drake J., Scapagnini G., and Calabrese V. Nutritional approaches to combat oxidative stress in Alzheimer's disease. J. Nutr. Biochem. 13 (2002) 444-461
3. Butterfield D.A. Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain, a review. Free Radic. Res. 36 (2002) 1307-1313
4. Chan C.C., and Lam P.T. Update on dementia. Part 1. Mild cognitive impairment, screening and diagnostic assessment. HK Pract. 27 (2005) 235-241
5. Chen Y.L., Hu C.S., Lin F.Y., Chen Y.H., Sheu L.M., Ku H.H., Shiao M.S., Chen J.W., and Lin S.J. Salvianolic acid B attenuates cyclooxygenase-2 expression in vitro in LPS-treated human aortic smooth muscle cells and in vivo in the apolipoprotein-E-deficient mouse aorta. J. Cell Biochem. 98 (2006) 618-631
6. Datki Z., Juhasz A., Galfi M., Soos K., Papp R., Zadori D., and Penke B. Method for measuring neurotoxicity of aggregating polypeptides with the MTT assay on differentiated neuroblastoma cells. Brain Res. Bull. 62 (2003) 223-229
7. Fujiwara H., Iwasaki K., Furukawa K., Seki T., He M., Maruyama M., Tomita N., Kudo Y., Higuchi M., Saido T.C., Maeda S., Takashima A., Hara M., Ohizumi Y., and Arai H. Uncaria rhynchophylla, a Chinese medicinal herb, has potent antiaggregation effects on Alzheimer's beta-amyloid proteins. J. Neurosci. Res. 84 (2006) 427-433
8. Jiang R.W., Lau K.M., Hon P.M., Mak T.C., Woo K.S., and Fung K.P. Chemistry and biological activities of caffeic acid derivatives from Salvia miltiorrhiza. Curr. Med. Chem. 12 (2005) 237-246
9. Kim S., Park S.Y., and Kim J.K. Curcuminoids from Curcuma longa L. (Zingiberaceae) that protect PC12 rat pheochromocytoma and normal human umbilical vein endothelial cells from Aβ (1-42) insult. Neurosci. Lett. 303 (2001) 57-61
10. Kirschner D.A., Abraham C., and Selkoe D.J. X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation. Proc. Natl. Acad. Sci. U.S.A. 83 (1986) 503-507
11. Lam F.F., Yeung J.H., Kwan Y.W., Chan K.M., and Or P.M. Salvianolic acid B, an aqueous component of danshen (Salvia miltiorrhiza), relaxes rat coronary artery by inhibition of calcium channels. Eur. J. Pharmacol. 553 (2006) 240-245
12. Lambert M.P., Velasco P.T., Chang L., Viola K.L., Fernandez S., Lacor P.N., Khuon D., Gong Y., Bigio E.H., Shaw P., De Felice F.G., Krafft G.A., and Klein W.L. Monoclonal antibodies that target pathological assemblies of Abeta. J. Neurochem. 100 (2007) 23-35
13. Lay I.S., Hsieh C.C., Chiu J.H., Shiao M.S., Lui W.Y., and Wu C.W. Salvianolic acid B enhances in vitro angiogenesis and improves skin flap survival in Sprague-Dawley rats. J. Surg. Res. 115 (2003) 279-285
14. Lay I.S., Chiu J.H., Shiao M.S., Lui W.Y., and Wu C.W. Crude extract of Salvia miltiorrhiza and salvianolic acid B enhance in vitro angiogenesis in murine SVR endothelial cell line. Planta Medica 69 (2003) 26-32
15. LeVine H. Alzheimer's β-peptide oligomer formation at physiologic concentrations. Anal. Biochem. 335 (2004) 81-90
16. Li M., Zhao C., Wong R.N.S., Goto S., Wang Z.M., and Liao F.L. Inhibition of shear-induced platelet aggregation in rat by tetramethylpyrazine and salvianolic acid B. Clin. Hemorheol. Microcirc. 31 (2004) 97-103
17. Li M., Zhao M.Q., Zhang H.X., Goto S., Wu W.K., and Liao F.L. Anti-apoptosis effects of tetramethylpyrazine and salvianolic acid B on rat cerebral microvascular endothelial cells under high shear stress. Biorheology 42 (2005) 57
18. Lin S.J., Lee I.T., Chen Y.H., Lin F.Y., Sheu L.M., Ku H.H., Shiao M.S., Chen J.W., and Chen L. Salvianolic acid B attenuates MMP-2 and MMP-9 expression in vivo in apolipoprotein-E-deficient mouse aorta and in vitro in LPS-treated human aortic smooth muscle cells. J. Cell Biochem. 100 (2007) 372-384
19. Lin Y.H., Liu A.H., Wu H.L., Westenbroek C., Song Q.L., Yu H.M., Ter Horst G.J., and Li X.J. Salvianolic acid B, an antioxidant from Salvia miltiorrhiza, prevents Abeta (25-35)-induced reduction in BPRP in PC12 cells. Biochem. Biophys. Res. Commun. 348 (2006) 593-599
20. Lleó A., Greenberg S.M., and Growdon J.H. Current pharmacotherapy for Alzheimer's disease. Ann. Rev. Med. 57 (2006) 513-533
21. Lorenzo A., and Yankner B.A. β-Amyloid neurotoxicity requires fibril formation and is inhibited by Congo red. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 12243-12247
22. Luo Y., Smith J.V., Paramasivam V., Burdick A., Curry K.J., Buford J.P., Khan I., Netzer W.J., Xu H., and Butko P. Inhibition of amyloid β aggregation and caspase-3 activation by the Ginkgo biloba extract EGb761. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 12197-12220
23. Munoz-Ruiz P., Rubio L., Garcia-Palomero E., Dorronsoro I., del Monte-Millan M., Valenzuela R., Usan P., de Austria C., Bartolini M., Andrisano V., Bidon-Chanal A., Orozco M., Luque F.J., Medina M., and Martinez A. Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: new disease-modifying agents for Alzheimer's disease. J. Med. Chem. 48 (2005) 7223-7233
24. Ono K., Hirohata M., and Yamada M. Ferulic acid destabilizes preformed beta-amyloid fibrils in vitro. Biochem. Biophys. Res. Commun. 336 (2005) 444-449
25. Ono K., Hamaguchi T., Naiki H., and Yamada M. Anti-amyloidogenic effects of antioxidants: implications for the prevention and therapeutics of Alzheimer's disease. Biochem. Biophys. Acta 1762 (2006) 575-586
26. Perez-Alvarez V., Bobadilla R.A., and Muriel P. Structure-hepatoprotective activity relationship of 3,4-dihydroxycinnamic acid (caffeic acid) derivatives. J. Appl. Toxicol. 21 (2001) 527-531
27. Reddy P.H. Amyloid precursor protein-mediated free radicals and oxidative damage: implications for the development and progression of Alzheimer's. J. Neurochem. 96 (2006) 1-13
28. Selkoe D.J. Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases. Nat. Cell Biol. 6 (2004) 1054-1061
29. Sreerama N., and Woody R.W. Computation and analysis of protein circular dichroism spectra. Methods Enzymol. 383 (2004) 318-351
30. Stackman R., Eckenstein F., Frei B., Kulhanek D., Nowlin J., and Quinn J.F. Prevention of age-related spatial memory deficits in a transgenic mouse model of Alzheimer's disease by chronic Ginkgo biloba treatment. Exp. Neurol. 18 (2003) 510-520
31. Sultana R., Ravagna A., Mohmmad-Abdul H., Calabrese V., and Butterfield D.A. Ferulic acid ethyl ester protects neurons against amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity. J. Neurochem. 92 (2005) 749-775
32. Tang M., and Zhang J. Prostate apoptosis response-4 involved in the protective effect of salvianolic acid B against amyloid beta peptide-induced damage in PC12 cells. Jpn. J. Pharmacol. 88 (2001) 422-427
33. Yang F., Mak K., Vinters H.V., Frautschy S.A., and Cole G.M. Monoclonal antibody to the C-terminus of β-amyloid. NeuroReport 5 (1994) 2117-2120
34. Yang F., Lim G.P., Begum A.N., Ubeda O.J., Simmons M.R., Ambegaokar S.S., Chen P.P., Kayed R., Glabe C.G., Frautschy S.A., and Cole G. Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo. J. Biol. Chem. 280 (2005) 5892-5901
35. Zhang H.S., and Wang S.Q. Salvianolic acid B from Salvia miltiorrhiza inhibits tumor necrosis factor-alpha (TNF-alpha)-induced MMP-2 upregulation in human aortic smooth muscle cells via suppression of NAD(P)H oxidase-derived reactive oxygen species. J. Mol. Cell Cardiol. 41 (2006) 38-48
36. Zhou L., Zuo Z., and Chow M.S. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J. Clin. Pharmacol. 45 (2005) 1345-1359