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Volumn 6, Issue 7, 2011, Pages

Honey bee PTEN - description, developmental knockdown, and tissue-specific expression of splice-variants correlated with alternative social phenotypes

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; SOMATOMEDIN; ISOPROTEIN;

EID: 79960326936     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022195     Document Type: Article
Times cited : (31)

References (94)
  • 1
    • 0142052858 scopus 로고    scopus 로고
    • Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans
    • Barbieri M, Bonafe M, Franceschi C, Paolisso G, (2003) Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans. Am J Physiol Endocrinol Metab 285: E1064-1071.
    • (2003) Am J Physiol Endocrinol Metab , vol.285 , pp. 1064-1071
    • Barbieri, M.1    Bonafe, M.2    Franceschi, C.3    Paolisso, G.4
  • 2
    • 0037306190 scopus 로고    scopus 로고
    • Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control
    • Oldham S, Hafen E, (2003) Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control. Trends Cell Biol 13: 79-85.
    • (2003) Trends Cell Biol , vol.13 , pp. 79-85
    • Oldham, S.1    Hafen, E.2
  • 4
    • 32044464123 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) signaling in cancer
    • Normanno N, De Luca A, Bianco C, Strizzi L, Mancino M, et al. (2006) Epidermal growth factor receptor (EGFR) signaling in cancer. Gene 366: 2-16.
    • (2006) Gene , vol.366 , pp. 2-16
    • Normanno, N.1    de Luca, A.2    Bianco, C.3    Strizzi, L.4    Mancino, M.5
  • 5
    • 24644436798 scopus 로고    scopus 로고
    • Obesity, insulin resistance and cancer risk
    • Jee SH, Kim HJ, Lee J, (2005) Obesity, insulin resistance and cancer risk. Yonsei Med J 46: 449-455.
    • (2005) Yonsei Med J , vol.46 , pp. 449-455
    • Jee, S.H.1    Kim, H.J.2    Lee, J.3
  • 7
    • 0035916357 scopus 로고    scopus 로고
    • An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control
    • Brogiolo W, Stocker H, Ikeya T, Rintelen F, Fernandez R, et al. (2001) An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control. Curr Biol 11: 213-221.
    • (2001) Curr Biol , vol.11 , pp. 213-221
    • Brogiolo, W.1    Stocker, H.2    Ikeya, T.3    Rintelen, F.4    Fernandez, R.5
  • 8
    • 17144415603 scopus 로고    scopus 로고
    • Role of insulin/insulin-like growth factor 1 signaling pathway in longevity
    • Cheng CL, Gao TQ, Wang Z, Li DD, (2005) Role of insulin/insulin-like growth factor 1 signaling pathway in longevity. World J Gastroenterol 11: 1891-1895.
    • (2005) World J Gastroenterol , vol.11 , pp. 1891-1895
    • Cheng, C.L.1    Gao, T.Q.2    Wang, Z.3    Li, D.D.4
  • 9
    • 0032981396 scopus 로고    scopus 로고
    • Regulation of the insulin-like developmental pathway of Caenorhabditis elegans by a homolog of the PTEN tumor suppressor gene
    • Gil EB, Malone Link E, Liu LX, Johnson CD, Lees JA, (1999) Regulation of the insulin-like developmental pathway of Caenorhabditis elegans by a homolog of the PTEN tumor suppressor gene. Proc Natl Acad Sci U S A 96: 2925-2930.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 2925-2930
    • Gil, E.B.1    Malone Link, E.2    Liu, L.X.3    Johnson, C.D.4    Lees, J.A.5
  • 10
    • 0033376684 scopus 로고    scopus 로고
    • PTEN affects cell size, cell proliferation and apoptosis during Drosophila eye development
    • Huang H, Potter CJ, Tao W, Li DM, Brogiolo W, et al. (1999) PTEN affects cell size, cell proliferation and apoptosis during Drosophila eye development. Development 126: 5365-5372.
    • (1999) Development , vol.126 , pp. 5365-5372
    • Huang, H.1    Potter, C.J.2    Tao, W.3    Li, D.M.4    Brogiolo, W.5
  • 11
    • 0034657764 scopus 로고    scopus 로고
    • Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways
    • Gao X, Neufeld TP, Pan D, (2000) Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and-independent pathways. Dev Biol 221: 404-418.
    • (2000) Dev Biol , vol.221 , pp. 404-418
    • Gao, X.1    Neufeld, T.P.2    Pan, D.3
  • 12
    • 33646063579 scopus 로고    scopus 로고
    • C. elegans DAF-18/PTEN mediates nutrient-dependent arrest of cell cycle and growth in the germline
    • Fukuyama M, Rougvie AE, Rothman JH, (2006) C. elegans DAF-18/PTEN mediates nutrient-dependent arrest of cell cycle and growth in the germline. Curr Biol 16: 773-779.
    • (2006) Curr Biol , vol.16 , pp. 773-779
    • Fukuyama, M.1    Rougvie, A.E.2    Rothman, J.H.3
  • 13
    • 0032238299 scopus 로고    scopus 로고
    • The C. elegans PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway
    • Ogg S, Ruvkun G, (1998) The C. elegans PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway. Mol Cell 2: 887-893.
    • (1998) Mol Cell , vol.2 , pp. 887-893
    • Ogg, S.1    Ruvkun, G.2
  • 14
    • 0036713481 scopus 로고    scopus 로고
    • The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP(3) levels
    • Oldham S, Stocker H, Laffargue M, Wittwer F, Wymann M, et al. (2002) The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP(3) levels. Development 129: 4103-4109.
    • (2002) Development , vol.129 , pp. 4103-4109
    • Oldham, S.1    Stocker, H.2    Laffargue, M.3    Wittwer, F.4    Wymann, M.5
  • 15
    • 60549116652 scopus 로고    scopus 로고
    • Haploinsufficiency for Pten and Serotonin transporter cooperatively influences brain size and social behavior
    • Page DT, Kuti OJ, Prestia C, Sur M, (2009) Haploinsufficiency for Pten and Serotonin transporter cooperatively influences brain size and social behavior. Proc Natl Acad Sci U S A 106: 1989-1994.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 1989-1994
    • Page, D.T.1    Kuti, O.J.2    Prestia, C.3    Sur, M.4
  • 16
    • 0033545921 scopus 로고    scopus 로고
    • When developmental pathways diverge
    • Nijhout HF, (1999) When developmental pathways diverge. Proc Natl Acad Sci USA 96: 5348-5350.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 5348-5350
    • Nijhout, H.F.1
  • 17
    • 79957613433 scopus 로고    scopus 로고
    • Royalactin induces queen differentiation in honeybees
    • Kamakura M, (2011) Royalactin induces queen differentiation in honeybees. Nature 473: 478-483.
    • (2011) Nature , vol.473 , pp. 478-483
    • Kamakura, M.1
  • 18
    • 33750431066 scopus 로고    scopus 로고
    • Expression of insulin pathway genes during the period of caste determination in the honey bee, Apis mellifera
    • Wheeler DE, Buck N, Evans JD, (2006) Expression of insulin pathway genes during the period of caste determination in the honey bee, Apis mellifera. Insect Mol Biol 15: 597-602.
    • (2006) Insect Mol Biol , vol.15 , pp. 597-602
    • Wheeler, D.E.1    Buck, N.2    Evans, J.D.3
  • 19
    • 34548539025 scopus 로고    scopus 로고
    • The making of a queen: TOR pathway governs diphenic caste development
    • Patel A, Fondrk MK, Kaftanoglu O, Emore C, Hunt G, et al. (2007) The making of a queen: TOR pathway governs diphenic caste development. PLoS ONE 6: e509.
    • (2007) PLoS ONE , vol.6
    • Patel, A.1    Fondrk, M.K.2    Kaftanoglu, O.3    Emore, C.4    Hunt, G.5
  • 20
    • 44749084339 scopus 로고    scopus 로고
    • The insulin signaling pathway in honey bee (Apis mellifera) caste development - differential expression of insulin-like peptides and insulin receptors in queen and worker larvae
    • de Azevedo SV, Hartfelder K, (2008) The insulin signaling pathway in honey bee (Apis mellifera) caste development- differential expression of insulin-like peptides and insulin receptors in queen and worker larvae. J Insect Physiol 54: 1064-1071.
    • (2008) J Insect Physiol , vol.54 , pp. 1064-1071
    • de Azevedo, S.V.1    Hartfelder, K.2
  • 21
    • 79551492162 scopus 로고    scopus 로고
    • Insulin receptor substrate influences female caste development in honeybees
    • doi: 101098/rsbl20100463
    • Wolschin F, Mutti NS, Amdam GV, (2010) Insulin receptor substrate influences female caste development in honeybees. Biol Lett doi:101098/rsbl20100463.
    • (2010) Biol Lett
    • Wolschin, F.1    Mutti, N.S.2    Amdam, G.V.3
  • 22
    • 79960290803 scopus 로고
    • Cambridge, MA, The Biology of the Honey Bee Harvard University Press
    • Winston ML, (1987) Cambridge, MA The Biology of the Honey Bee Harvard University Press.
    • (1987)
    • Winston, M.L.1
  • 23
    • 23644450922 scopus 로고    scopus 로고
    • Intergenerational transfers may have decoupled physiological and chronological age in a eusocial insect
    • Amdam GV, Page RE Jr, (2005) Intergenerational transfers may have decoupled physiological and chronological age in a eusocial insect. Ageing Res Rev 4: 398-408.
    • (2005) Ageing Res Rev , vol.4 , pp. 398-408
    • Amdam, G.V.1    Page Jr., R.E.2
  • 24
    • 34147116930 scopus 로고    scopus 로고
    • The making of a social insect: developmental architectures of social design
    • Page RE Jr, Amdam GV, (2007) The making of a social insect: developmental architectures of social design. Bioessays 29: 334-343.
    • (2007) Bioessays , vol.29 , pp. 334-343
    • Page Jr., R.E.1    Amdam, G.V.2
  • 25
    • 33745952047 scopus 로고    scopus 로고
    • The development and evolution of division of labor and foraging specialization in a social insect (Apis mellifera L.)
    • Page RE Jr, Scheiner R, Erber J, Amdam GV, (2006) The development and evolution of division of labor and foraging specialization in a social insect (Apis mellifera L.). Curr Top Dev Biol 74: 253-286.
    • (2006) Curr Top Dev Biol , vol.74 , pp. 253-286
    • Page Jr., R.E.1    Scheiner, R.2    Erber, J.3    Amdam, G.V.4
  • 26
    • 34250801470 scopus 로고    scopus 로고
    • Variation in endocrine signaling underlies variation in social life history
    • Amdam GV, Nilsen KA, Norberg K, Fondrk MK, Hartfelder K, (2007) Variation in endocrine signaling underlies variation in social life history. Am Nat 170: 37-46.
    • (2007) Am Nat , vol.170 , pp. 37-46
    • Amdam, G.V.1    Nilsen, K.A.2    Norberg, K.3    Fondrk, M.K.4    Hartfelder, K.5
  • 27
    • 0032147211 scopus 로고    scopus 로고
    • Effects of social environment and worker mandibular glands on endocrine-mediated behavioral development in honey bees
    • Huang Z-Y, Plettner E, Robinson GE, (1998) Effects of social environment and worker mandibular glands on endocrine-mediated behavioral development in honey bees. J Comp Physiol A 183: 143-152.
    • (1998) J Comp Physiol A , vol.183 , pp. 143-152
    • Huang, Z.-Y.1    Plettner, E.2    Robinson, G.E.3
  • 28
    • 0027097556 scopus 로고
    • Honeybee colony integration: Worker-worker interactions mediate hormonally regulated plasticity in division of labor
    • Huang Z-Y, Robinson GE, (1992) Honeybee colony integration: Worker-worker interactions mediate hormonally regulated plasticity in division of labor. Proc Natl Acad Sci USA 89: 11726-11729.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11726-11729
    • Huang, Z.-Y.1    Robinson, G.E.2
  • 30
    • 34548532541 scopus 로고    scopus 로고
    • Comparative proteomics reveal characteristics of life-history transitions in a social insect
    • Wolschin F, Amdam GV, (2007) Comparative proteomics reveal characteristics of life-history transitions in a social insect. Proteome Sci 5: 10.
    • (2007) Proteome Sci , vol.5 , pp. 10
    • Wolschin, F.1    Amdam, G.V.2
  • 31
    • 3843125168 scopus 로고    scopus 로고
    • Reproductive ground plan may mediate colony-level selection effects on individual foraging behavior in honey bees
    • Amdam GV, Norberg K, Fondrk MK, Page RE Jr, (2004) Reproductive ground plan may mediate colony-level selection effects on individual foraging behavior in honey bees. Proc Natl Acad Sci U S A 101: 11350-11355.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 11350-11355
    • Amdam, G.V.1    Norberg, K.2    Fondrk, M.K.3    Page Jr., R.E.4
  • 32
    • 41949087745 scopus 로고    scopus 로고
    • Insulin signaling is involved in the regulation of worker division of labor in honey bee colonies
    • Ament SA, Corona M, Pollock HS, Robinson GE, (2008) Insulin signaling is involved in the regulation of worker division of labor in honey bee colonies. Proc Natl Acad Sci U S A 105: 4226-4231.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 4226-4231
    • Ament, S.A.1    Corona, M.2    Pollock, H.S.3    Robinson, G.E.4
  • 33
    • 84884796952 scopus 로고    scopus 로고
    • Regulation of honey bee (Apis mellifera) life histories by vitellogenin
    • In: Pfaff D, Arnold A, Etgen A, Fahrbach S, Rubin R, editors, San Diego, CA, Elsevier Academic Press,2 Ed
    • Amdam GV, Ihle KE, Page RE, (2009) Regulation of honey bee (Apis mellifera) life histories by vitellogenin. In: Pfaff D, Arnold A, Etgen A, Fahrbach S, Rubin R, editors. Hormones, Brain and Behavior. 2 ed San Diego, CA Elsevier Academic Press.
    • (2009) Hormones, Brain and Behavior
    • Amdam, G.V.1    Ihle, K.E.2    Page, R.E.3
  • 35
    • 0000174222 scopus 로고
    • Influence of diet, age and colony condition upon intestinal proteolytic activity and size of the hypopharyngeal glands in the honeybee (Apis mellifera L.)
    • Crailsheim K, Stolberg E, (1989) Influence of diet, age and colony condition upon intestinal proteolytic activity and size of the hypopharyngeal glands in the honeybee (Apis mellifera L.). J Insect Physiol 35: 595-602.
    • (1989) J Insect Physiol , vol.35 , pp. 595-602
    • Crailsheim, K.1    Stolberg, E.2
  • 36
  • 37
    • 0031835182 scopus 로고    scopus 로고
    • Effects of colony food shortage on behavioral development in honey bees
    • Schulz DJ, Huang ZY, Robinson GE, (1998) Effects of colony food shortage on behavioral development in honey bees. Behav Ecol Sociobiol 42: 295-303.
    • (1998) Behav Ecol Sociobiol , vol.42 , pp. 295-303
    • Schulz, D.J.1    Huang, Z.Y.2    Robinson, G.E.3
  • 39
    • 34248377260 scopus 로고    scopus 로고
    • Characterization of phosphatase and tensin homolog expression in the mosquito Aedes aegypti: six splice variants with developmental and tissue specificity
    • Riehle MA, Brown JM, (2007) Characterization of phosphatase and tensin homolog expression in the mosquito Aedes aegypti: six splice variants with developmental and tissue specificity. Insect Mol Biol 16: 277-286.
    • (2007) Insect Mol Biol , vol.16 , pp. 277-286
    • Riehle, M.A.1    Brown, J.M.2
  • 40
    • 33645054569 scopus 로고    scopus 로고
    • Downregulation of vitellogenin gene activity increases the gustatory responsiveness of honey bee workers (Apis mellifera)
    • Amdam GV, Norberg K, Page RE Jr, Erber J, Scheiner R, (2006) Downregulation of vitellogenin gene activity increases the gustatory responsiveness of honey bee workers (Apis mellifera). Behav Brain Res 169: 201-205.
    • (2006) Behav Brain Res , vol.169 , pp. 201-205
    • Amdam, G.V.1    Norberg, K.2    Page Jr., R.E.3    Erber, J.4    Scheiner, R.5
  • 41
    • 48249136098 scopus 로고    scopus 로고
    • A protein from the salivary glands of the pea aphid, Acyrthosiphon pisum, is essential in feeding on a host plant
    • Mutti NS, Louis J, Pappan LK, Pappan K, Begum K, et al. (2008) A protein from the salivary glands of the pea aphid, Acyrthosiphon pisum, is essential in feeding on a host plant. Proc Natl Acad Sci U S A 105: 9965-9969.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 9965-9969
    • Mutti, N.S.1    Louis, J.2    Pappan, L.K.3    Pappan, K.4    Begum, K.5
  • 42
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 43
    • 77952399280 scopus 로고    scopus 로고
    • Down-regulation of honey bee IRS gene biases behavior toward food rich in protein
    • Wang Y, Mutti NS, Ihle KE, Siegel A, Dolezal AG, et al. (2010) Down-regulation of honey bee IRS gene biases behavior toward food rich in protein. PLoS Genet 6: e1000896.
    • (2010) PLoS Genet , vol.6
    • Wang, Y.1    Mutti, N.S.2    Ihle, K.E.3    Siegel, A.4    Dolezal, A.G.5
  • 45
    • 33750460281 scopus 로고    scopus 로고
    • Insights into social insects from the genome of the honeybee Apis mellifera
    • Consortium THGS
    • Consortium THGS (2006) Insights into social insects from the genome of the honeybee Apis mellifera. Nature 443: 931-949.
    • (2006) Nature , vol.443 , pp. 931-949
  • 46
    • 33144470077 scopus 로고    scopus 로고
    • Differential expression of novel naturally occurring splice variants of PTEN and their functional consequences in Cowden syndrome and sporadic breast cancer
    • Agrawal S, Eng C, (2006) Differential expression of novel naturally occurring splice variants of PTEN and their functional consequences in Cowden syndrome and sporadic breast cancer. Hum Mol Genet 15: 777-787.
    • (2006) Hum Mol Genet , vol.15 , pp. 777-787
    • Agrawal, S.1    Eng, C.2
  • 47
    • 0038272084 scopus 로고    scopus 로고
    • Membrane-binding and activation mechanism of PTEN
    • Das S, Dixon JE, Cho W, (2003) Membrane-binding and activation mechanism of PTEN. Proc Natl Acad Sci U S A 100: 7491-7496.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 7491-7496
    • Das, S.1    Dixon, J.E.2    Cho, W.3
  • 48
    • 0033615538 scopus 로고    scopus 로고
    • Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association
    • Lee JO, Yang H, Georgescu MM, Di Cristofano A, Maehama T, et al. (1999) Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. Cell 99: 323-334.
    • (1999) Cell , vol.99 , pp. 323-334
    • Lee, J.O.1    Yang, H.2    Georgescu, M.M.3    Di Cristofano, A.4    Maehama, T.5
  • 49
    • 33646705667 scopus 로고    scopus 로고
    • Regulation of the PTEN phosphatase
    • Gericke A, Munson M, Ross AH, (2006) Regulation of the PTEN phosphatase. Gene 374: 1-9.
    • (2006) Gene , vol.374 , pp. 1-9
    • Gericke, A.1    Munson, M.2    Ross, A.H.3
  • 51
    • 0033572644 scopus 로고    scopus 로고
    • Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway
    • Goberdhan DC, Paricio N, Goodman EC, Mlodzik M, Wilson C, (1999) Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway. Genes Dev 13: 3244-3258.
    • (1999) Genes Dev , vol.13 , pp. 3244-3258
    • Goberdhan, D.C.1    Paricio, N.2    Goodman, E.C.3    Mlodzik, M.4    Wilson, C.5
  • 52
    • 13144249184 scopus 로고    scopus 로고
    • High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
    • Suzuki A, de la Pompa JL, Stambolic V, Elia AJ, Sasaki T, et al. (1998) High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice. Current Biology 8: 1169-1178.
    • (1998) Current Biology , vol.8 , pp. 1169-1178
    • Suzuki, A.1    de la Pompa, J.L.2    Stambolic, V.3    Elia, A.J.4    Sasaki, T.5
  • 53
    • 0032578911 scopus 로고    scopus 로고
    • Specific interference by ingested dsRNA
    • Timmons L, Fire A, (1998) Specific interference by ingested dsRNA. Nature 395: 854.
    • (1998) Nature , vol.395 , pp. 854
    • Timmons, L.1    Fire, A.2
  • 54
    • 46849111425 scopus 로고    scopus 로고
    • RNA interference in the termite Reticulitermes flavipes through ingestion of double-stranded RNA
    • Zhou X, Wheeler MM, Oi FM, Scharf ME, (2008) RNA interference in the termite Reticulitermes flavipes through ingestion of double-stranded RNA. Insect Biochem Mol Biol 38: 805-815.
    • (2008) Insect Biochem Mol Biol , vol.38 , pp. 805-815
    • Zhou, X.1    Wheeler, M.M.2    Oi, F.M.3    Scharf, M.E.4
  • 55
    • 58549099123 scopus 로고    scopus 로고
    • Prolonged gene knockdown in the tsetse fly Glossina by feeding double stranded RNA
    • Walshe DP, Lehane SM, Lehane MJ, Haines LR, (2009) Prolonged gene knockdown in the tsetse fly Glossina by feeding double stranded RNA. Insect Mol Biol 18: 11-19.
    • (2009) Insect Mol Biol , vol.18 , pp. 11-19
    • Walshe, D.P.1    Lehane, S.M.2    Lehane, M.J.3    Haines, L.R.4
  • 56
    • 24044534508 scopus 로고    scopus 로고
    • Capillary feeding of specific dsRNA induces silencing of the isac gene in nymphal Ixodes scapularis ticks
    • Soares CA, Lima CM, Dolan MC, Piesman J, Beard CB, et al. (2005) Capillary feeding of specific dsRNA induces silencing of the isac gene in nymphal Ixodes scapularis ticks. Insect Mol Biol 14: 443-452.
    • (2005) Insect Mol Biol , vol.14 , pp. 443-452
    • Soares, C.A.1    Lima, C.M.2    Dolan, M.C.3    Piesman, J.4    Beard, C.B.5
  • 57
    • 0033551070 scopus 로고    scopus 로고
    • New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
    • Cantley LC, Neel BG, (1999) New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proc Natl Acad Sci U S A 96: 4240-4245.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 4240-4245
    • Cantley, L.C.1    Neel, B.G.2
  • 58
    • 0031004088 scopus 로고    scopus 로고
    • Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
    • Liaw D, Marsh DJ, Li J, Dahia PL, Wang SI, et al. (1997) Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat Genet 16: 64-67.
    • (1997) Nat Genet , vol.16 , pp. 64-67
    • Liaw, D.1    Marsh, D.J.2    Li, J.3    Dahia, P.L.4    Wang, S.I.5
  • 59
    • 0032568662 scopus 로고    scopus 로고
    • C2-domains, structure and function of a universal Ca2+-binding domain
    • Rizo J, Sudhof TC, (1998) C2-domains, structure and function of a universal Ca2+-binding domain. J Biol Chem 273: 15879-15882.
    • (1998) J Biol Chem , vol.273 , pp. 15879-15882
    • Rizo, J.1    Sudhof, T.C.2
  • 60
    • 0034636038 scopus 로고    scopus 로고
    • Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2
    • Wu X, Hepner K, Castelino-Prabhu S, Do D, Kaye MB, et al. (2000) Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2. Proc Natl Acad Sci U S A 97: 4233-4238.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 4233-4238
    • Wu, X.1    Hepner, K.2    Castelino-Prabhu, S.3    Do, D.4    Kaye, M.B.5
  • 61
    • 23844473290 scopus 로고    scopus 로고
    • Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases
    • Valiente M, Andres-Pons A, Gomar B, Torres J, Gil A, et al. (2005) Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases. J Biol Chem 280: 28936-28943.
    • (2005) J Biol Chem , vol.280 , pp. 28936-28943
    • Valiente, M.1    Andres-Pons, A.2    Gomar, B.3    Torres, J.4    Gil, A.5
  • 62
    • 2442650370 scopus 로고    scopus 로고
    • The action of ARGONAUTE1 in the miRNA pathway and its regulation by the miRNA pathway are crucial for plant development
    • Vaucheret H, Vazquez F, Crete P, Bartel DP, (2004) The action of ARGONAUTE1 in the miRNA pathway and its regulation by the miRNA pathway are crucial for plant development. Genes Dev 18: 1187-1197.
    • (2004) Genes Dev , vol.18 , pp. 1187-1197
    • Vaucheret, H.1    Vazquez, F.2    Crete, P.3    Bartel, D.P.4
  • 63
    • 16244391770 scopus 로고    scopus 로고
    • Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology
    • Griffin RJ, Moloney A, Kelliher M, Johnston JA, Ravid R, et al. (2005) Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology. J Neurochem 93: 105-117.
    • (2005) J Neurochem , vol.93 , pp. 105-117
    • Griffin, R.J.1    Moloney, A.2    Kelliher, M.3    Johnston, J.A.4    Ravid, R.5
  • 64
    • 33646697973 scopus 로고    scopus 로고
    • Regulation of the lipid phosphatase PTEN
    • Maehama T, (2006) [Regulation of the lipid phosphatase PTEN]. Seikagaku 78: 133-137.
    • (2006) Seikagaku , vol.78 , pp. 133-137
    • Maehama, T.1
  • 66
    • 1642538990 scopus 로고    scopus 로고
    • Vector-based in vivo RNA interference: dose- and time-dependent suppression of transgene expression
    • Kobayashi N, Matsui Y, Kawase A, Hirata K, Miyagishi M, et al. (2004) Vector-based in vivo RNA interference: dose- and time-dependent suppression of transgene expression. J Pharmacol Exp Ther 308: 688-693.
    • (2004) J Pharmacol Exp Ther , vol.308 , pp. 688-693
    • Kobayashi, N.1    Matsui, Y.2    Kawase, A.3    Hirata, K.4    Miyagishi, M.5
  • 68
    • 77949423993 scopus 로고    scopus 로고
    • RNAi-mediated knockdown of AURKB and EGFR shows enhanced therapeutic efficacy in prostate tumor regression
    • Addepalli MK, Ray KB, Kumar B, Ramnath RL, Chile S, et al. (2009) RNAi-mediated knockdown of AURKB and EGFR shows enhanced therapeutic efficacy in prostate tumor regression. Gene Ther 17: 352-359.
    • (2009) Gene Ther , vol.17 , pp. 352-359
    • Addepalli, M.K.1    Ray, K.B.2    Kumar, B.3    Ramnath, R.L.4    Chile, S.5
  • 69
    • 41949104147 scopus 로고    scopus 로고
    • Exploring systemic RNA interference in insects: a genome-wide survey for RNAi genes in Tribolium
    • Tomoyasu Y, Miller SC, Tomita S, Schoppmeier M, Grossmann D, et al. (2008) Exploring systemic RNA interference in insects: a genome-wide survey for RNAi genes in Tribolium. Genome Biol 9: R10.
    • (2008) Genome Biol , vol.9
    • Tomoyasu, Y.1    Miller, S.C.2    Tomita, S.3    Schoppmeier, M.4    Grossmann, D.5
  • 70
    • 0036898747 scopus 로고    scopus 로고
    • Specific developmental gene silencing in the honey bee using a homeobox motif
    • Beye M, Hartel S, Hagen A, Hasselmann M, Omholt SW, (2002) Specific developmental gene silencing in the honey bee using a homeobox motif. Insect Mol Biol 11: 527-532.
    • (2002) Insect Mol Biol , vol.11 , pp. 527-532
    • Beye, M.1    Hartel, S.2    Hagen, A.3    Hasselmann, M.4    Omholt, S.W.5
  • 71
    • 34249076321 scopus 로고    scopus 로고
    • The regulation of genes and genomes by small RNAs
    • Ambros V, Chen X, (2007) The regulation of genes and genomes by small RNAs. Development 134: 1635-1641.
    • (2007) Development , vol.134 , pp. 1635-1641
    • Ambros, V.1    Chen, X.2
  • 73
    • 34248671430 scopus 로고    scopus 로고
    • Novel insights into RNAi off-target effects using C-elegans paralogs
    • Rual JF, Klitgord N, Achaz G, (2007) Novel insights into RNAi off-target effects using C-elegans paralogs. Bmc Genomics 8.
    • (2007) Bmc Genomics , vol.8
    • Rual, J.F.1    Klitgord, N.2    Achaz, G.3
  • 74
    • 0035882527 scopus 로고    scopus 로고
    • Experience- and age-related outgrowth of intrinsic neurons in the mushroom bodies of the adult worker honeybee
    • Farris SM, Robinson GE, Fahrbach SE, (2001) Experience- and age-related outgrowth of intrinsic neurons in the mushroom bodies of the adult worker honeybee. J Neurosci 21: 6395-6404.
    • (2001) J Neurosci , vol.21 , pp. 6395-6404
    • Farris, S.M.1    Robinson, G.E.2    Fahrbach, S.E.3
  • 75
    • 30444432203 scopus 로고    scopus 로고
    • Stimulation of muscarinic receptors mimics experience-dependent plasticity in the honey bee brain
    • Ismail N, Robinson GE, Fahrbach SE, (2006) Stimulation of muscarinic receptors mimics experience-dependent plasticity in the honey bee brain. Proc Natl Acad Sci U S A 103: 207-211.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 207-211
    • Ismail, N.1    Robinson, G.E.2    Fahrbach, S.E.3
  • 76
    • 0029101633 scopus 로고
    • Neurogenesis is absent in the brains of adult honey bees and does not explain behavioral neuroplasticity
    • Fahrbach SE, Strande JL, Robinson GE, (1995) Neurogenesis is absent in the brains of adult honey bees and does not explain behavioral neuroplasticity. Neurosci Lett 197: 145-148.
    • (1995) Neurosci Lett , vol.197 , pp. 145-148
    • Fahrbach, S.E.1    Strande, J.L.2    Robinson, G.E.3
  • 77
    • 77951437255 scopus 로고    scopus 로고
    • Branching out: mechanisms of dendritic arborization
    • Jan YN, Jan LY, (2010) Branching out: mechanisms of dendritic arborization. Nat Rev Neurosci 11: 316-328.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 316-328
    • Jan, Y.N.1    Jan, L.Y.2
  • 78
    • 34548258389 scopus 로고    scopus 로고
    • PTEN plays a role in the suppression of lateral pseudopod formation during Dictyostelium motility and chemotaxis
    • Wessels D, Lusche DF, Kuhl S, Heid P, Soll DR, (2007) PTEN plays a role in the suppression of lateral pseudopod formation during Dictyostelium motility and chemotaxis. J Cell Sci 120: 2517-2531.
    • (2007) J Cell Sci , vol.120 , pp. 2517-2531
    • Wessels, D.1    Lusche, D.F.2    Kuhl, S.3    Heid, P.4    Soll, D.R.5
  • 79
    • 0029361288 scopus 로고
    • Behavioral development in the honey bee: toward the study of learning under natural conditions
    • Fahrbach SE, Robinson GE, (1995) Behavioral development in the honey bee: toward the study of learning under natural conditions. Learn Mem 2: 199-224.
    • (1995) Learn Mem , vol.2 , pp. 199-224
    • Fahrbach, S.E.1    Robinson, G.E.2
  • 80
    • 0035826521 scopus 로고    scopus 로고
    • Responsiveness to sucrose affects tactile and olfactory learning in preforaging honey bees of two genetic strains
    • Scheiner R, Page RE Jr, Erber J, (2001) Responsiveness to sucrose affects tactile and olfactory learning in preforaging honey bees of two genetic strains. Behav Brain Res 120: 67-73.
    • (2001) Behav Brain Res , vol.120 , pp. 67-73
    • Scheiner, R.1    Page Jr., R.E.2    Erber, J.3
  • 81
    • 38849108820 scopus 로고    scopus 로고
    • Oocyte-specific deletion of Pten causes premature activation of the primordial follicle pool
    • Reddy P, Liu L, Adhikari D, Jagarlamudi K, Rajareddy S, et al. (2008) Oocyte-specific deletion of Pten causes premature activation of the primordial follicle pool. Science 319: 611-613.
    • (2008) Science , vol.319 , pp. 611-613
    • Reddy, P.1    Liu, L.2    Adhikari, D.3    Jagarlamudi, K.4    Rajareddy, S.5
  • 82
    • 0032851279 scopus 로고    scopus 로고
    • Influence of age and population size on ovarian development, and of trophallaxis on ovarian development and vitellogenin titres of queenless worker honey bee (Hymenoptera: Apidae)
    • Lin H, Winston ML, Haunerland NH, Slessor KN, (1999) Influence of age and population size on ovarian development, and of trophallaxis on ovarian development and vitellogenin titres of queenless worker honey bee (Hymenoptera: Apidae). Can Entomol 131: 695-706.
    • (1999) Can Entomol , vol.131 , pp. 695-706
    • Lin, H.1    Winston, M.L.2    Haunerland, N.H.3    Slessor, K.N.4
  • 84
    • 24144451079 scopus 로고    scopus 로고
    • Vitellogenin regulates hormonal dynamics in the worker caste of a eusocial insect
    • Guidugli KR, Nascimento AM, Amdam GV, Barchuk AR, Omholt S, et al. (2005) Vitellogenin regulates hormonal dynamics in the worker caste of a eusocial insect. FEBS Lett 579: 4961-4965.
    • (2005) FEBS Lett , vol.579 , pp. 4961-4965
    • Guidugli, K.R.1    Nascimento, A.M.2    Amdam, G.V.3    Barchuk, A.R.4    Omholt, S.5
  • 85
    • 33947281456 scopus 로고    scopus 로고
    • The Gene vitellogenin Has Multiple Coordinating Effects on Social Organization
    • Nelson CM, Ihle KE, Fondrk MK, Page RE, Amdam GV, (2007) The Gene vitellogenin Has Multiple Coordinating Effects on Social Organization. PLoS Biol 5: e62.
    • (2007) PLoS Biol , vol.5
    • Nelson, C.M.1    Ihle, K.E.2    Fondrk, M.K.3    Page, R.E.4    Amdam, G.V.5
  • 88
    • 33846436789 scopus 로고    scopus 로고
    • A steroid hormone that extends the lifespan of Caenorhabditis elegans
    • Broue F, Liere P, Kenyon C, Baulieu EE, (2007) A steroid hormone that extends the lifespan of Caenorhabditis elegans. Aging Cell 6: 87-94.
    • (2007) Aging Cell , vol.6 , pp. 87-94
    • Broue, F.1    Liere, P.2    Kenyon, C.3    Baulieu, E.E.4
  • 89
    • 34548645020 scopus 로고    scopus 로고
    • Caenorhabditis elegans integrates food and reproductive signals in lifespan determination
    • Crawford D, Libina N, Kenyon C, (2007) Caenorhabditis elegans integrates food and reproductive signals in lifespan determination. Aging Cell 6: 715-721.
    • (2007) Aging Cell , vol.6 , pp. 715-721
    • Crawford, D.1    Libina, N.2    Kenyon, C.3
  • 90
    • 0034613164 scopus 로고    scopus 로고
    • Regulation of C. elegans life-span by insulinlike signaling in the nervous system
    • Wolkow CA, Kimura KD, Lee M-S, Ruvkun G, (2000) Regulation of C. elegans life-span by insulinlike signaling in the nervous system. Science 290: 147-150.
    • (2000) Science , vol.290 , pp. 147-150
    • Wolkow, C.A.1    Kimura, K.D.2    Lee, M.-S.3    Ruvkun, G.4
  • 91
    • 79960287600 scopus 로고    scopus 로고
    • Amdam GV Social context, stress, and plasticity of aging
    • Amdam GV Social context, stress, and plasticity of aging. Aging Cell.
    • Aging Cell
  • 92
    • 0038718939 scopus 로고    scopus 로고
    • The hive bee to forager transition in honeybee colonies: the double repressor hypothesis
    • Amdam GV, Omholt SW, (2003) The hive bee to forager transition in honeybee colonies: the double repressor hypothesis. J Theor Biol 223: 451-464.
    • (2003) J Theor Biol , vol.223 , pp. 451-464
    • Amdam, G.V.1    Omholt, S.W.2
  • 93
    • 0033980929 scopus 로고    scopus 로고
    • Inhibition of vitellogenin synthesis in Apis mellifera workers by a juvenile hormone analogue, pyriproxyfen
    • Pinto LZ, Bitondi MMG, Simões ZLP, (2000) Inhibition of vitellogenin synthesis in Apis mellifera workers by a juvenile hormone analogue, pyriproxyfen. J Insect Physiol 46: 153-160.
    • (2000) J Insect Physiol , vol.46 , pp. 153-160
    • Pinto, L.Z.1    Bitondi, M.M.G.2    Simões, Z.L.P.3
  • 94
    • 0034855915 scopus 로고    scopus 로고
    • Juvenile hormone levels in honey bee (Apis mellifera L.) foragers: foraging experience and diurnal variation
    • Elekonich MM, Schulz DJ, Bloch G, Robinson GE, (2001) Juvenile hormone levels in honey bee (Apis mellifera L.) foragers: foraging experience and diurnal variation. J Insect Physiol 47: 1119-1125.
    • (2001) J Insect Physiol , vol.47 , pp. 1119-1125
    • Elekonich, M.M.1    Schulz, D.J.2    Bloch, G.3    Robinson, G.E.4


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