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Volumn 10, Issue 9, 2010, Pages 1068-1076

Negative modulation of invariant natural killer T cell responses to glycolipid antigens by p38 MAP kinase

Author keywords

galactosylceramide; MAPK; NKT cell; P38; Signaling

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 6 (4 FLUOROPHENYL) 2,3 DIHYDRO 5 (4 PYRIDYL)IMIDAZO[2,1 B]THIAZOLE; ALPHA GALACTOSYLCERAMIDE; ANTIGEN; CD1D ANTIGEN; GAMMA INTERFERON; GLYCOLIPID; INTERLEUKIN 2; INTERLEUKIN 4; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; MONOCLONAL ANTIBODY CD3; STRESS ACTIVATED PROTEIN KINASE; T LYMPHOCYTE RECEPTOR;

EID: 77955923293     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2010.06.007     Document Type: Article
Times cited : (8)

References (52)
  • 1
    • 0027966063 scopus 로고
    • Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes
    • Lanier L.L., Chang C., Phillips J.H. Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes. J Immunol 1994, 153:2417-2428.
    • (1994) J Immunol , vol.153 , pp. 2417-2428
    • Lanier, L.L.1    Chang, C.2    Phillips, J.H.3
  • 3
    • 0023192930 scopus 로고
    • A novel population of T-cell receptor alpha beta-bearing thymocytes which predominantly expresses a single V beta gene family
    • Fowlkes B.J., Kruisbeek A.M., Ton-That H., et al. A novel population of T-cell receptor alpha beta-bearing thymocytes which predominantly expresses a single V beta gene family. Nature 1987, 329:251-254.
    • (1987) Nature , vol.329 , pp. 251-254
    • Fowlkes, B.J.1    Kruisbeek, A.M.2    Ton-That, H.3
  • 4
    • 0028025074 scopus 로고
    • An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans
    • Lantz O., Bendelac A. An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans. J Exp Med 1994, 180:1097-1106.
    • (1994) J Exp Med , vol.180 , pp. 1097-1106
    • Lantz, O.1    Bendelac, A.2
  • 5
    • 17144374753 scopus 로고    scopus 로고
    • Toward an understanding of NKT cell biology: progress and paradoxes
    • Kronenberg M. Toward an understanding of NKT cell biology: progress and paradoxes. Annu Rev Immunol 2005, 23:877-900.
    • (2005) Annu Rev Immunol , vol.23 , pp. 877-900
    • Kronenberg, M.1
  • 6
    • 0030826423 scopus 로고    scopus 로고
    • Crystal structure of mouse CD1: an MHC-like fold with a large hydrophobic binding groove
    • Zeng Z., Castano A.R., Segelke B.W., Stura E.A., Peterson P.A., Wilson I.A. Crystal structure of mouse CD1: an MHC-like fold with a large hydrophobic binding groove. Science 1997, 277:339-345.
    • (1997) Science , vol.277 , pp. 339-345
    • Zeng, Z.1    Castano, A.R.2    Segelke, B.W.3    Stura, E.A.4    Peterson, P.A.5    Wilson, I.A.6
  • 7
    • 0037816187 scopus 로고    scopus 로고
    • Mouse V alpha 14i natural killer T cells are resistant to cytokine polarization in vivo
    • Matsuda J.L., Gapin L., Baron J.L., et al. Mouse V alpha 14i natural killer T cells are resistant to cytokine polarization in vivo. Proc Natl Acad Sci USA 2003, 100:8395-8400.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8395-8400
    • Matsuda, J.L.1    Gapin, L.2    Baron, J.L.3
  • 8
    • 0141924778 scopus 로고    scopus 로고
    • Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function
    • Stetson D.B., Mohrs M., Reinhardt R.L., et al. Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function. J Exp Med 2003, 198:1069-1076.
    • (2003) J Exp Med , vol.198 , pp. 1069-1076
    • Stetson, D.B.1    Mohrs, M.2    Reinhardt, R.L.3
  • 9
    • 4644221871 scopus 로고    scopus 로고
    • Quantitative and qualitative differences in the in vivo response of NKT cells to distinct alpha- and beta-anomeric glycolipids
    • Parekh V.V., Singh A.K., Wilson M.T., et al. Quantitative and qualitative differences in the in vivo response of NKT cells to distinct alpha- and beta-anomeric glycolipids. J Immunol 2004, 173:3693-3706.
    • (2004) J Immunol , vol.173 , pp. 3693-3706
    • Parekh, V.V.1    Singh, A.K.2    Wilson, M.T.3
  • 10
    • 18044392378 scopus 로고    scopus 로고
    • Immunotherapeutic potential for ceramide-based activators of iNKT cells
    • Berkers C.R., Ovaa H. Immunotherapeutic potential for ceramide-based activators of iNKT cells. Trends Pharmacol Sci 2005, 26:252-257.
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 252-257
    • Berkers, C.R.1    Ovaa, H.2
  • 11
    • 0030696696 scopus 로고    scopus 로고
    • CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides
    • Kawano T., Cui J., Koezuka Y., et al. CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides. Science 1997, 278:1626-1629.
    • (1997) Science , vol.278 , pp. 1626-1629
    • Kawano, T.1    Cui, J.2    Koezuka, Y.3
  • 12
    • 38049065867 scopus 로고    scopus 로고
    • Application of natural killer T cells in antitumor immunotherapy
    • Hong C., Park S.H. Application of natural killer T cells in antitumor immunotherapy. Crit Rev Immunol 2007, 27:511-525.
    • (2007) Crit Rev Immunol , vol.27 , pp. 511-525
    • Hong, C.1    Park, S.H.2
  • 13
    • 56849090964 scopus 로고    scopus 로고
    • The role of NKT cells in tumor immunity
    • Terabe M., Berzofsky J.A. The role of NKT cells in tumor immunity. Adv Cancer Res 2008, 101:277-348.
    • (2008) Adv Cancer Res , vol.101 , pp. 277-348
    • Terabe, M.1    Berzofsky, J.A.2
  • 14
    • 41149095047 scopus 로고    scopus 로고
    • Invariant natural killer T cells in immune surveillance and tumor immunotherapy: perspectives and potentials
    • Haeryfar S.M. Invariant natural killer T cells in immune surveillance and tumor immunotherapy: perspectives and potentials. Arch Iran Med 2008, 11:186-195.
    • (2008) Arch Iran Med , vol.11 , pp. 186-195
    • Haeryfar, S.M.1
  • 15
    • 34547445595 scopus 로고    scopus 로고
    • Randomized placebo controlled phase I/II trial of alpha-galactosylceramide for the treatment of chronic hepatitis C
    • Veldt B.J., van d V., von Blomberg B.M., et al. Randomized placebo controlled phase I/II trial of alpha-galactosylceramide for the treatment of chronic hepatitis C. J Hepatol 2007, 47:356-365.
    • (2007) J Hepatol , vol.47 , pp. 356-365
    • Veldt, B.J.1    van d, V.2    von Blomberg, B.M.3
  • 16
    • 72049133156 scopus 로고    scopus 로고
    • Alpha-galactosylceramide in chronic hepatitis B infection: results from a randomized placebo-controlled Phase I/II trial
    • Woltman A.M., Ter Borg M.J., Binda R.S., et al. Alpha-galactosylceramide in chronic hepatitis B infection: results from a randomized placebo-controlled Phase I/II trial. Antivir Ther 2009, 14:809-818.
    • (2009) Antivir Ther , vol.14 , pp. 809-818
    • Woltman, A.M.1    Ter Borg, M.J.2    Binda, R.S.3
  • 18
    • 38149085101 scopus 로고    scopus 로고
    • Regulatory mechanisms of mitogen-activated kinase signaling
    • Zhang Y., Dong C. Regulatory mechanisms of mitogen-activated kinase signaling. Cell Mol Life Sci 2007, 64:2771-2789.
    • (2007) Cell Mol Life Sci , vol.64 , pp. 2771-2789
    • Zhang, Y.1    Dong, C.2
  • 19
    • 1542269020 scopus 로고    scopus 로고
    • Targeting the JNK MAPK cascade for inhibition: basic science and therapeutic potential
    • Bogoyevitch M.A., Boehm I., Oakley A., Ketterman A.J., Barr R.K. Targeting the JNK MAPK cascade for inhibition: basic science and therapeutic potential. Biochim Biophys Acta 2004, 1697:89-101.
    • (2004) Biochim Biophys Acta , vol.1697 , pp. 89-101
    • Bogoyevitch, M.A.1    Boehm, I.2    Oakley, A.3    Ketterman, A.J.4    Barr, R.K.5
  • 20
    • 33646165882 scopus 로고    scopus 로고
    • New approaches to the treatment of inflammatory disorders small molecule inhibitors of p38 MAP kinase
    • Peifer C., Wagner G., Laufer S. New approaches to the treatment of inflammatory disorders small molecule inhibitors of p38 MAP kinase. Curr Top Med Chem 2006, 6:113-149.
    • (2006) Curr Top Med Chem , vol.6 , pp. 113-149
    • Peifer, C.1    Wagner, G.2    Laufer, S.3
  • 21
    • 0030613856 scopus 로고    scopus 로고
    • Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors
    • Cui J., Shin T., Kawano T., et al. Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors. Science 1997, 278:1623-1626.
    • (1997) Science , vol.278 , pp. 1623-1626
    • Cui, J.1    Shin, T.2    Kawano, T.3
  • 22
    • 0028605318 scopus 로고
    • A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
    • Lee J.C., Laydon J.T., McDonnell P.C., et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 1994, 372:739-746.
    • (1994) Nature , vol.372 , pp. 739-746
    • Lee, J.C.1    Laydon, J.T.2    McDonnell, P.C.3
  • 23
    • 27544465416 scopus 로고    scopus 로고
    • Regulation of IkappaBalpha expression involves both NF-kappaB and the MAP kinase signaling pathways
    • Zhang N., Ahsan M.H., Zhu L., Sambucetti L.C., Purchio A.F., West D.B. Regulation of IkappaBalpha expression involves both NF-kappaB and the MAP kinase signaling pathways. J Inflam (Lond) 2005, 2:10.
    • (2005) J Inflam (Lond) , vol.2 , pp. 10
    • Zhang, N.1    Ahsan, M.H.2    Zhu, L.3    Sambucetti, L.C.4    Purchio, A.F.5    West, D.B.6
  • 24
    • 77952780797 scopus 로고    scopus 로고
    • Inhibition of the p38 MAP kinase in vivo improves number and functional activity of vasculogenic cells and reduces atherosclerotic disease progression
    • Seeger F.H., Sedding D., Langheinrich A.C., Haendeler J., Zeiher A.M., Dimmeler S. Inhibition of the p38 MAP kinase in vivo improves number and functional activity of vasculogenic cells and reduces atherosclerotic disease progression. Basic Res Cardiol 2010, 105:389-397.
    • (2010) Basic Res Cardiol , vol.105 , pp. 389-397
    • Seeger, F.H.1    Sedding, D.2    Langheinrich, A.C.3    Haendeler, J.4    Zeiher, A.M.5    Dimmeler, S.6
  • 25
    • 17944366298 scopus 로고    scopus 로고
    • Preclinical pharmacokinetics of SB-203580, a potent inhibitor of p38 mitogen-activated protein kinase
    • Ward K.W., Prokscht J.W., Azzaranot L.M., et al. Preclinical pharmacokinetics of SB-203580, a potent inhibitor of p38 mitogen-activated protein kinase. Xenobiotica 2001, 31:783-797.
    • (2001) Xenobiotica , vol.31 , pp. 783-797
    • Ward, K.W.1    Prokscht, J.W.2    Azzaranot, L.M.3
  • 26
    • 0032853934 scopus 로고    scopus 로고
    • Cutting edge: NKT cell development is selectively impaired in Fyn-deficient mice
    • Eberl G., Lowin-Kropf B., MacDonald H.R. Cutting edge: NKT cell development is selectively impaired in Fyn-deficient mice. J Immunol 1999, 163:4091-4094.
    • (1999) J Immunol , vol.163 , pp. 4091-4094
    • Eberl, G.1    Lowin-Kropf, B.2    MacDonald, H.R.3
  • 27
    • 0032723181 scopus 로고    scopus 로고
    • The Src family tyrosine kinase Fyn regulates natural killer T cell development
    • Gadue P., Morton N., Stein P.L. The Src family tyrosine kinase Fyn regulates natural killer T cell development. J Exp Med 1999, 190:1189-1196.
    • (1999) J Exp Med , vol.190 , pp. 1189-1196
    • Gadue, P.1    Morton, N.2    Stein, P.L.3
  • 28
    • 49149113472 scopus 로고    scopus 로고
    • The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival
    • Felices M., Berg L.J. The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival. J Immunol 2008, 180:3007-3018.
    • (2008) J Immunol , vol.180 , pp. 3007-3018
    • Felices, M.1    Berg, L.J.2
  • 29
    • 33745530860 scopus 로고    scopus 로고
    • The many paths to p38 mitogen-activated protein kinase activation in the immune system
    • Ashwell J.D. The many paths to p38 mitogen-activated protein kinase activation in the immune system. Nat Rev Immunol 2006, 6:532-540.
    • (2006) Nat Rev Immunol , vol.6 , pp. 532-540
    • Ashwell, J.D.1
  • 31
    • 0035102237 scopus 로고    scopus 로고
    • Selective pharmacological inhibitors reveal differences between Thy-1- and T cell receptor-mediated signal transduction in mouse T lymphocytes
    • Haeryfar S.M., Hoskin D.W. Selective pharmacological inhibitors reveal differences between Thy-1- and T cell receptor-mediated signal transduction in mouse T lymphocytes. Int Immunopharmacol 2001, 1:689-698.
    • (2001) Int Immunopharmacol , vol.1 , pp. 689-698
    • Haeryfar, S.M.1    Hoskin, D.W.2
  • 32
    • 0035923665 scopus 로고    scopus 로고
    • SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
    • Bennett B.L., Sasaki D.T., Murray B.W., et al. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci USA 2001, 98:13681-13686.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 13681-13686
    • Bennett, B.L.1    Sasaki, D.T.2    Murray, B.W.3
  • 33
    • 0033120052 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase mediates signal integration of TCR/CD28 costimulation in primary murine T cells
    • Zhang J., Salojin K.V., Gao J.X., Cameron M.J., Bergerot I., Delovitch T.L. p38 mitogen-activated protein kinase mediates signal integration of TCR/CD28 costimulation in primary murine T cells. J Immunol 1999, 162:3819-3829.
    • (1999) J Immunol , vol.162 , pp. 3819-3829
    • Zhang, J.1    Salojin, K.V.2    Gao, J.X.3    Cameron, M.J.4    Bergerot, I.5    Delovitch, T.L.6
  • 34
    • 25444514465 scopus 로고    scopus 로고
    • Virus-induced inhibition of CD1d1-mediated antigen presentation: reciprocal regulation by p38 and ERK
    • Renukaradhya G.J., Webb T.J., Khan M.A., et al. Virus-induced inhibition of CD1d1-mediated antigen presentation: reciprocal regulation by p38 and ERK. J Immunol 2005, 175:4301-4308.
    • (2005) J Immunol , vol.175 , pp. 4301-4308
    • Renukaradhya, G.J.1    Webb, T.J.2    Khan, M.A.3
  • 35
    • 0022618123 scopus 로고
    • T cell activation by anti-T3 antibodies: comparison of IgG1 and IgG2b switch variants and direct evidence for accessory function of macrophage Fc receptors
    • Smith K.G., Austyn J.M., Hariri G., Beverley P.C., Morris P.J. T cell activation by anti-T3 antibodies: comparison of IgG1 and IgG2b switch variants and direct evidence for accessory function of macrophage Fc receptors. Eur J Immunol 1986, 16:478-486.
    • (1986) Eur J Immunol , vol.16 , pp. 478-486
    • Smith, K.G.1    Austyn, J.M.2    Hariri, G.3    Beverley, P.C.4    Morris, P.J.5
  • 36
    • 34249331264 scopus 로고    scopus 로고
    • Novel strategies for inhibition of the p38 MAPK pathway
    • Zhang J., Shen B., Lin A. Novel strategies for inhibition of the p38 MAPK pathway. Trends Pharmacol Sci 2007, 28:286-295.
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 286-295
    • Zhang, J.1    Shen, B.2    Lin, A.3
  • 37
    • 0033520376 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase is involved in Fas ligand expression
    • Hsu S.C., Gavrilin M.A., Tsai M.H., Han J., Lai M.Z. p38 mitogen-activated protein kinase is involved in Fas ligand expression. J Biol Chem 1999, 274:25769-25776.
    • (1999) J Biol Chem , vol.274 , pp. 25769-25776
    • Hsu, S.C.1    Gavrilin, M.A.2    Tsai, M.H.3    Han, J.4    Lai, M.Z.5
  • 38
    • 0033548597 scopus 로고    scopus 로고
    • Murine p38-delta mitogen-activated protein kinase, a developmentally regulated protein kinase that is activated by stress and proinflammatory cytokines
    • Hu M.C., Wang Y.P., Mikhail A., Qiu W.R., Tan T.H. Murine p38-delta mitogen-activated protein kinase, a developmentally regulated protein kinase that is activated by stress and proinflammatory cytokines. J Biol Chem 1999, 274:7095-7102.
    • (1999) J Biol Chem , vol.274 , pp. 7095-7102
    • Hu, M.C.1    Wang, Y.P.2    Mikhail, A.3    Qiu, W.R.4    Tan, T.H.5
  • 39
    • 0033581478 scopus 로고    scopus 로고
    • Integrin alpha2beta1 mediates isoform-specific activation of p38 and upregulation of collagen gene transcription by a mechanism involving the alpha2 cytoplasmic tail
    • Ivaska J., Reunanen H., Westermarck J., Koivisto L., Kahari V.M., Heino J. Integrin alpha2beta1 mediates isoform-specific activation of p38 and upregulation of collagen gene transcription by a mechanism involving the alpha2 cytoplasmic tail. J Cell Biol 1999, 147:401-416.
    • (1999) J Cell Biol , vol.147 , pp. 401-416
    • Ivaska, J.1    Reunanen, H.2    Westermarck, J.3    Koivisto, L.4    Kahari, V.M.5    Heino, J.6
  • 40
    • 63749083925 scopus 로고    scopus 로고
    • Targeting protein kinases for the development of anti-inflammatory drugs
    • Cohen P. Targeting protein kinases for the development of anti-inflammatory drugs. Curr Opin Cell Biol 2009, 21:317-324.
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 317-324
    • Cohen, P.1
  • 41
    • 11244304412 scopus 로고    scopus 로고
    • Alpha-Galactosylceramide therapy for autoimmune diseases: prospects and obstacles
    • Van K.L. alpha-Galactosylceramide therapy for autoimmune diseases: prospects and obstacles. Nat Rev Immunol 2005, 5:31-42.
    • (2005) Nat Rev Immunol , vol.5 , pp. 31-42
    • Van, K.L.1
  • 42
    • 46949111220 scopus 로고    scopus 로고
    • IL-2 triggers specific signaling pathways in human NKT cells leading to the production of pro- and anti-inflammatory cytokines
    • Bessoles S., Fouret F., Dudal S., Besra G.S., Sanchez F., Lafont V. IL-2 triggers specific signaling pathways in human NKT cells leading to the production of pro- and anti-inflammatory cytokines. J Leukoc Biol 2008, 84:224-233.
    • (2008) J Leukoc Biol , vol.84 , pp. 224-233
    • Bessoles, S.1    Fouret, F.2    Dudal, S.3    Besra, G.S.4    Sanchez, F.5    Lafont, V.6
  • 43
    • 70349677168 scopus 로고    scopus 로고
    • Bacillus anthracis lethal toxin disrupts TCR signaling in CD1d-restricted NKT cells leading to functional anergy
    • Joshi S.K., Lang G.A., Larabee J.L., et al. Bacillus anthracis lethal toxin disrupts TCR signaling in CD1d-restricted NKT cells leading to functional anergy. PLoS Pathog 2009, 5:e1000588.
    • (2009) PLoS Pathog , vol.5
    • Joshi, S.K.1    Lang, G.A.2    Larabee, J.L.3
  • 44
    • 34447131000 scopus 로고    scopus 로고
    • CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor
    • Borg N.A., Wun K.S., Kjer-Nielsen L., et al. CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor. Nature 2007, 448:44-49.
    • (2007) Nature , vol.448 , pp. 44-49
    • Borg, N.A.1    Wun, K.S.2    Kjer-Nielsen, L.3
  • 46
    • 27744562232 scopus 로고    scopus 로고
    • Differential antitumor immunity mediated by NKT cell subsets in vivo
    • Crowe N.Y., Coquet J.M., Berzins S.P., et al. Differential antitumor immunity mediated by NKT cell subsets in vivo. J Exp Med 2005, 202:1279-1288.
    • (2005) J Exp Med , vol.202 , pp. 1279-1288
    • Crowe, N.Y.1    Coquet, J.M.2    Berzins, S.P.3
  • 47
    • 0032547849 scopus 로고    scopus 로고
    • CD1d-mediated recognition of an alpha-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution
    • Brossay L., Chioda M., Burdin N., et al. CD1d-mediated recognition of an alpha-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution. J Exp Med 1998, 188:1521-1528.
    • (1998) J Exp Med , vol.188 , pp. 1521-1528
    • Brossay, L.1    Chioda, M.2    Burdin, N.3
  • 48
    • 0345167831 scopus 로고    scopus 로고
    • Superior protection against malaria and melanoma metastases by a C-glycoside analogue of the natural killer T cell ligand alpha-Galactosylceramide
    • Schmieg J., Yang G., Franck R.W., Tsuji M. Superior protection against malaria and melanoma metastases by a C-glycoside analogue of the natural killer T cell ligand alpha-Galactosylceramide. J Exp Med 2003, 198:1631-1641.
    • (2003) J Exp Med , vol.198 , pp. 1631-1641
    • Schmieg, J.1    Yang, G.2    Franck, R.W.3    Tsuji, M.4
  • 49
    • 0035807302 scopus 로고    scopus 로고
    • A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells
    • Miyamoto K., Miyake S., Yamamura T. A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells. Nature 2001, 413:531-534.
    • (2001) Nature , vol.413 , pp. 531-534
    • Miyamoto, K.1    Miyake, S.2    Yamamura, T.3
  • 50
    • 20044387608 scopus 로고    scopus 로고
    • Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of alpha-galactosylceramides
    • Yu K.O., Im J.S., Molano A., et al. Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of alpha-galactosylceramides. Proc Natl Acad Sci USA 2005, 102:3383-3388.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 3383-3388
    • Yu, K.O.1    Im, J.S.2    Molano, A.3
  • 51
    • 43649088780 scopus 로고    scopus 로고
    • Phage display-derived recombinant antibodies with TCR-like specificity against alpha-galactosylceramide and its analogues in complex with human CD1d molecules
    • Denkberg G., Stronge V.S., Zahavi E., et al. Phage display-derived recombinant antibodies with TCR-like specificity against alpha-galactosylceramide and its analogues in complex with human CD1d molecules. Eur J Immunol 2008, 38:829-840.
    • (2008) Eur J Immunol , vol.38 , pp. 829-840
    • Denkberg, G.1    Stronge, V.S.2    Zahavi, E.3
  • 52
    • 34249054887 scopus 로고    scopus 로고
    • The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation
    • McCarthy C., Shepherd D., Fleire S., et al. The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation. J Exp Med 2007, 204:1131-1144.
    • (2007) J Exp Med , vol.204 , pp. 1131-1144
    • McCarthy, C.1    Shepherd, D.2    Fleire, S.3


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