Residual type 1 immunity in patients genetically deficient for interleukin 12 receptor β1 (IL-12Rβ1): Evidence for an IL-12Rβ1-independent pathway of IL-12 responsiveness in human T cells

Journal of Experimental Medicine

Volumn 192, Issue 4, 2000, Pages 517-528

  Verhagen, Claudia E ^a   De Boer, Tjitske ^a   Smits, Hermelijn H ^b   Verreck, Frank A W ^a   Wierenga, Eddy A ^b   Kurimoto, M ^c   Lammas, D Anthony ^d   Kumararatne, Dinakanthe S ^d   Sanal, Ozden ^e   Kroon, Frank P ^a   Van Dissel, Jaap T ^a   Sinigaglia, Francesco ^f   Ottenhoff, Tom H M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c HAYASHIBARA BIOCHEMICAL LABORATORIES INC   (Japan)

^d UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^e HACETTEPE UNIVERSITY   (Turkey)

^f ROCHE MILANO RICERCHE   (Italy)

Author keywords

Interferon ; Interleukin 12 (receptor); Interleukin 18 (receptor); Mycobacteria; Th1

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 18; INTERLEUKIN 18 RECEPTOR; INTERLEUKIN 2 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; STAT4 PROTEIN;

ADULT; ARTICLE; BACTERIAL INFECTION; CASE REPORT; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GENETIC DISORDER; GENETIC TRANSCRIPTION; HELPER CELL; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; MALE; MYCOBACTERIOSIS; PRESCHOOL CHILD; PRIORITY JOURNAL; SALMONELLOSIS; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ADOLESCENT; ADULT; ANTIGENS, CD; BUTADIENES; CHILD; CHILD, PRESCHOOL; DNA-BINDING PROTEINS; ENZYME INHIBITORS; FEMALE; HUMANS; IMIDAZOLES; INFANT; INTEGRIN ALPHA6; INTERFERON TYPE II; INTERFERON-ALPHA; INTERLEUKIN-12; INTERLEUKIN-18; INTERLEUKIN-18 RECEPTOR ALPHA SUBUNIT; INTERLEUKIN-4; MALE; MYCOBACTERIUM AVIUM-INTRACELLULARE INFECTION; NITRILES; PROTO-ONCOGENE PROTEINS C-MYC; PYRIDINES; RECEPTOR, INTERFERON ALPHA-BETA; RECEPTORS, INTERFERON; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-12; RECEPTORS, INTERLEUKIN-18; SALMONELLA INFECTIONS; SIGNAL TRANSDUCTION; STAT4 TRANSCRIPTION FACTOR; T-LYMPHOCYTES; TH1 CELLS; TRANS-ACTIVATORS;

EID: 0034698827     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.192.4.517     Document Type: Article

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