메뉴 건너뛰기




Volumn 174, Issue 3, 2005, Pages 1239-1244

MAPK p38α is dispensable for lymphocyte development and proliferation

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE P38; RAG2 PROTEIN;

EID: 12444257323     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.174.3.1239     Document Type: Article
Times cited : (44)

References (45)
  • 1
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • Johnson, G. L., and R. Lapadat. 2002. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 298:1911.
    • (2002) Science , vol.298 , pp. 1911
    • Johnson, G.L.1    Lapadat, R.2
  • 3
    • 0033613273 scopus 로고    scopus 로고
    • Signal transduction by MAP kinases: Regulation by phosphorylation- dependent switches
    • Whitmarsh, A. J., and R. J. Davis. 1999. Signal transduction by MAP kinases: regulation by phosphorylation-dependent switches. Sci. STKE 1999:PE1.
    • (1999) Sci. STKE , vol.1999
    • Whitmarsh, A.J.1    Davis, R.J.2
  • 4
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • Chang, L., and M. Karin. 2001. Mammalian MAP kinase signalling cascades. Nature 410:37.
    • (2001) Nature , vol.410 , pp. 37
    • Chang, L.1    Karin, M.2
  • 5
    • 0026743949 scopus 로고
    • Purification of a murine protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product: Relationship to the fission yeast byr1 gene product
    • Crews, C. M., and R. L. Erikson. 1992. Purification of a murine protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product: relationship to the fission yeast byr1 gene product. Proc. Natl. Acad. Sci. USA 89:8205.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 8205
    • Crews, C.M.1    Erikson, R.L.2
  • 6
    • 0026773119 scopus 로고
    • Identification of an activator of the microtubule-associated protein 2 kinases ERK1 and ERK2 in PC12 cells stimulated with nerve growth factor or bradykinin
    • Ahn, N. G., D. J. Robbins, J. W. Haycock, R. Seger, M. H. Cobb, and E. G. Krebs. 1992. Identification of an activator of the microtubule-associated protein 2 kinases ERK1 and ERK2 in PC12 cells stimulated with nerve growth factor or bradykinin. J. Neurochem. 59:147.
    • (1992) J. Neurochem. , vol.59 , pp. 147
    • Ahn, N.G.1    Robbins, D.J.2    Haycock, J.W.3    Seger, R.4    Cobb, M.H.5    Krebs, E.G.6
  • 7
    • 0028935974 scopus 로고
    • Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms
    • Derijard, B., J. Raingeaud, T. Barrett, I. H. Wu, J. Han, R. J. Ulevitch, and R. J. Davis. 1995. Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms. Science 267:682.
    • (1995) Science , vol.267 , pp. 682
    • Derijard, B.1    Raingeaud, J.2    Barrett, T.3    Wu, I.H.4    Han, J.5    Ulevitch, R.J.6    Davis, R.J.7
  • 9
    • 0027936755 scopus 로고
    • A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
    • Han, J., J. D. Lee, L. Bibbs, and R. J. Ulevitch. 1994. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265:808.
    • (1994) Science , vol.265 , pp. 808
    • Han, J.1    Lee, J.D.2    Bibbs, L.3    Ulevitch, R.J.4
  • 10
    • 0028935270 scopus 로고
    • Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
    • Raingeaud, J., S. Gupta, J. S. Rogers, M. Dickens, J. Han, R. J. Ulevitch, and R. J. Davis. 1995. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J. Biol. Chem. 270:7420.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7420
    • Raingeaud, J.1    Gupta, S.2    Rogers, J.S.3    Dickens, M.4    Han, J.5    Ulevitch, R.J.6    Davis, R.J.7
  • 12
    • 0033582459 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase pathway promotes skeletal muscle differentiation: Participation of the Mef2c transcription factor
    • Zetser, A., E. Gredinger, and E. Bengal. 1999. p38 mitogen-activated protein kinase pathway promotes skeletal muscle differentiation: participation of the Mef2c transcription factor. J. Biol. Chem. 274:5193.
    • (1999) J. Biol. Chem. , vol.274 , pp. 5193
    • Zetser, A.1    Gredinger, E.2    Bengal, E.3
  • 13
    • 0034213138 scopus 로고    scopus 로고
    • p38 MAP kinases: Beyond the stress response
    • Nebreda, A. R., and A. Porras. 2000. p38 MAP kinases: beyond the stress response. Trends Biochem. Sci. 25:257.
    • (2000) Trends Biochem. Sci. , vol.25 , pp. 257
    • Nebreda, A.R.1    Porras, A.2
  • 14
    • 0034162714 scopus 로고    scopus 로고
    • Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells
    • Puri, P. L., Z. Wu, P. Zhang, L. D. Wood, K. S. Bhakta, J. Han, J. R. Feramisco, M. Karin, and J. Y. Wang. 2000. Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells. Genes Dev. 14:574.
    • (2000) Genes Dev. , vol.14 , pp. 574
    • Puri, P.L.1    Wu, Z.2    Zhang, P.3    Wood, L.D.4    Bhakta, K.S.5    Han, J.6    Feramisco, J.R.7    Karin, M.8    Wang, J.Y.9
  • 16
    • 0031714391 scopus 로고    scopus 로고
    • Signaling from G-protein-coupled receptors to mitogen-activated protein (MAP)-kinase cascades
    • Lopez-Ilasaca, M. 1998. Signaling from G-protein-coupled receptors to mitogen-activated protein (MAP)-kinase cascades. Biochem. Pharmacol. 56:269.
    • (1998) Biochem. Pharmacol. , vol.56 , pp. 269
    • Lopez-Ilasaca, M.1
  • 17
    • 0030581626 scopus 로고    scopus 로고
    • The primary structure of p38 γ: A new member of p38 group of MAP kinases
    • Li, Z., Y. Jiang, R. J. Ulevitch, and J. Han. 1996. The primary structure of p38 γ: a new member of p38 group of MAP kinases. Biochem. Biophys. Res. Commun. 228:334.
    • (1996) Biochem. Biophys. Res. Commun. , vol.228 , pp. 334
    • Li, Z.1    Jiang, Y.2    Ulevitch, R.J.3    Han, J.4
  • 18
    • 0029982565 scopus 로고    scopus 로고
    • Characterization of the structure and function of a new mitogen-activated protein kinase (p38β)
    • Jiang, Y., C. Chen, Z. Li, W. Guo, J. A. Gegner, S. Lin, and J. Han. 1996. Characterization of the structure and function of a new mitogen-activated protein kinase (p38β). J. Biol Chem. 271:17920.
    • (1996) J. Biol Chem. , vol.271 , pp. 17920
    • Jiang, Y.1    Chen, C.2    Li, Z.3    Guo, W.4    Gegner, J.A.5    Lin, S.6    Han, J.7
  • 19
    • 0030927106 scopus 로고    scopus 로고
    • Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases
    • Goedert, M., A. Cuenda, M. Craxton, R. Jakes, and P. Cohen. 1997. Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases. EMBO J. 16:3563.
    • (1997) EMBO J. , vol.16 , pp. 3563
    • Goedert, M.1    Cuenda, A.2    Craxton, M.3    Jakes, R.4    Cohen, P.5
  • 20
    • 0030044182 scopus 로고    scopus 로고
    • Characterization of the structure and function of a novel MAP kinase kinase (MKK6)
    • Han, J., J. D. Lee, Y. Jiang, Z. Li, L. Feng, and R. J. Ulevitch. 1996. Characterization of the structure and function of a novel MAP kinase kinase (MKK6). J. Biol. Chem. 271:2886.
    • (1996) J. Biol. Chem. , vol.271 , pp. 2886
    • Han, J.1    Lee, J.D.2    Jiang, Y.3    Li, Z.4    Feng, L.5    Ulevitch, R.J.6
  • 23
    • 0036549872 scopus 로고    scopus 로고
    • Cardiac expression and subcellular localization of the p38 mitogen-activated protein kinase member, stress-activated protein kinase-3 (SAPK3)
    • Court, N. W., C. G. dos Remedios, J. Cordell, and M. A. Bogoyevitch. 2002. Cardiac expression and subcellular localization of the p38 mitogen-activated protein kinase member, stress-activated protein kinase-3 (SAPK3). J. Mol. Cell. Cardiol. 34:413.
    • (2002) J. Mol. Cell. Cardiol. , vol.34 , pp. 413
    • Court, N.W.1    Dos Remedios, C.G.2    Cordell, J.3    Bogoyevitch, M.A.4
  • 24
    • 0033120590 scopus 로고    scopus 로고
    • Differential expression and activation of p38 mitogen-activated protein kinase α, β, γ, and δ in inflammatory cell lineages
    • Hale, K. K., D. Trollinger, M. Rihanek, and C. L. Manthey. 1999. Differential expression and activation of p38 mitogen-activated protein kinase α, β, γ, and δ in inflammatory cell lineages. J. Immunol. 162:4246.
    • (1999) J. Immunol. , vol.162 , pp. 4246
    • Hale, K.K.1    Trollinger, D.2    Rihanek, M.3    Manthey, C.L.4
  • 27
    • 0034610981 scopus 로고    scopus 로고
    • Deficiency of the stress kinase p38α results in embryonic lethality: Characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells
    • Allen, M., L. Svensson, M. Roach, J. Hambor, J. McNeish, and C. A. Gabel. 2000. Deficiency of the stress kinase p38α results in embryonic lethality: characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells. J. Exp. Med. 191:859.
    • (2000) J. Exp. Med. , vol.191 , pp. 859
    • Allen, M.1    Svensson, L.2    Roach, M.3    Hambor, J.4    McNeish, J.5    Gabel, C.A.6
  • 29
    • 0034697904 scopus 로고    scopus 로고
    • Requirement for p38α in erythropoietin expression: A role for stress kinases in erythropoiesis
    • Tamura, K., T. Sudo, U. Senftleben, A. M. Dadak, R. Johnson, and M. Karin, 2000. Requirement for p38α in erythropoietin expression: a role for stress kinases in erythropoiesis. Cell 102:221.
    • (2000) Cell , vol.102 , pp. 221
    • Tamura, K.1    Sudo, T.2    Senftleben, U.3    Dadak, A.M.4    Johnson, R.5    Karin, M.6
  • 30
    • 0034781509 scopus 로고    scopus 로고
    • p38 MAP kinase activity modulates αβ T cell development
    • Mulroy, T., and J. Sen. 2001. p38 MAP kinase activity modulates αβ T cell development. Eur. J. Immunol. 31:3056.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 3056
    • Mulroy, T.1    Sen, J.2
  • 31
    • 0032191837 scopus 로고    scopus 로고
    • Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes
    • Sugawara, T., T. Moriguchi, E. Nishida, and Y. Takahama. 1998. Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes. Immunity 9:565.
    • (1998) Immunity , vol.9 , pp. 565
    • Sugawara, T.1    Moriguchi, T.2    Nishida, E.3    Takahama, Y.4
  • 32
    • 0033030207 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase inhibitors: Mechanisms and therapeutic potentials
    • Lee, J. C., S. Kassis, S. Kumar, A. Badger, and J. L. Adams. 1999. p38 mitogen-activated protein kinase inhibitors: mechanisms and therapeutic potentials, Pharmacol. Ther. 82:389.
    • (1999) Pharmacol. Ther. , vol.82 , pp. 389
    • Lee, J.C.1    Kassis, S.2    Kumar, S.3    Badger, A.4    Adams, J.L.5
  • 33
    • 0037307045 scopus 로고    scopus 로고
    • Involvement of p38 mitogen-activated protein kinase in different stages of thymocyte development
    • Hsu, S. C., C. C. Wu, J. Han, and M. Z. Lai. 2003. Involvement of p38 mitogen-activated protein kinase in different stages of thymocyte development. Blood 101:970.
    • (2003) Blood , vol.101 , pp. 970
    • Hsu, S.C.1    Wu, C.C.2    Han, J.3    Lai, M.Z.4
  • 34
    • 0034677067 scopus 로고    scopus 로고
    • Activation of the p38 mitogen-activated protein kinase pathway arrests cell cycle progression and differentiation of immature thymocytes in vivo
    • Diehl, N. L., H. Enslen, K. A. Fortner, C. Merritt, N. Stetson, C. Charland, R. A. Flavell, R. J. Davis, and M. Rincon. 2000. Activation of the p38 mitogen-activated protein kinase pathway arrests cell cycle progression and differentiation of immature thymocytes in vivo. J. Exp. Med. 191:321.
    • (2000) J. Exp. Med. , vol.191 , pp. 321
    • Diehl, N.L.1    Enslen, H.2    Fortner, K.A.3    Merritt, C.4    Stetson, N.5    Charland, C.6    Flavell, R.A.7    Davis, R.J.8    Rincon, M.9
  • 36
    • 0030903693 scopus 로고    scopus 로고
    • T cell proliferation in response to interleukins 2 and 7 requires p38MAP kinase activation
    • Crawley, J. B., L. Rawlinson, F. V. Lali, T. H. Page, J. Saklatvala, and B. M. Foxwell. 1997. T cell proliferation in response to interleukins 2 and 7 requires p38MAP kinase activation. J. Biol. Chem. 272:15023.
    • (1997) J. Biol. Chem. , vol.272 , pp. 15023
    • Crawley, J.B.1    Rawlinson, L.2    Lali, F.V.3    Page, T.H.4    Saklatvala, J.5    Foxwell, B.M.6
  • 37
    • 0035261399 scopus 로고    scopus 로고
    • IL-18-stimulated GADD45 β required in cytokine-induced, but not TCR-induced. IFN-γ production
    • Yang, J., H. Zhu, T. L. Murphy, W. Ouyang, and K. M. Murphy. 2001. IL-18-stimulated GADD45 β required in cytokine-induced, but not TCR-induced. IFN-γ production. Nat. Immunol. 2:157.
    • (2001) Nat. Immunol. , vol.2 , pp. 157
    • Yang, J.1    Zhu, H.2    Murphy, T.L.3    Ouyang, W.4    Murphy, K.M.5
  • 38
    • 0029992125 scopus 로고    scopus 로고
    • Intramymic signals in thymocytes are mediated by p38 mitogen-activated protein kinase
    • Sen, J., R. Kapeller, R. Fragoso, R. Sen, L. I. Zon, and S. J. Burakoff. 1996. Intramymic signals in thymocytes are mediated by p38 mitogen-activated protein kinase. J. Immunol. 156:4535.
    • (1996) J. Immunol. , vol.156 , pp. 4535
    • Sen, J.1    Kapeller, R.2    Fragoso, R.3    Sen, R.4    Zon, L.I.5    Burakoff, S.J.6
  • 39
    • 0037131425 scopus 로고    scopus 로고
    • Molecular mechanisms of pre-T cell receptor-induced survival
    • Murga, C., and D. F. Barber. 2002. Molecular mechanisms of pre-T cell receptor-induced survival. J. Biol. Chem. 277:39156.
    • (2002) J. Biol. Chem. , vol.277 , pp. 39156
    • Murga, C.1    Barber, D.F.2
  • 40
    • 0027215522 scopus 로고
    • RAG-2-deficient blastocyst complementation: An assay of gene function in lymphocyte development
    • Chen, J., R. Lansford, V. Stewart, F. Young, and F. W. Alt. 1993. RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development. Proc. Natl. Acad. Sci. USA 90:4528.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4528
    • Chen, J.1    Lansford, R.2    Stewart, V.3    Young, F.4    Alt, F.W.5
  • 42
    • 0016811399 scopus 로고
    • B lymphocyte differentiation induced by lipopolysaccharide. I. Generation of cells synthesizing four major immunoglobulin classes
    • Kearney, J. F., and A. R. Lawton. 1975. B lymphocyte differentiation induced by lipopolysaccharide. I. Generation of cells synthesizing four major immunoglobulin classes. J. Immunol. 115:671.
    • (1975) J. Immunol. , vol.115 , pp. 671
    • Kearney, J.F.1    Lawton, A.R.2
  • 43
    • 0035847076 scopus 로고    scopus 로고
    • Selective targeting of MAPKs to the ETS domain transcription factor SAP-1
    • Galanis, A., S. H. Yang, and A. D. Sharrocks. 2001. Selective targeting of MAPKs to the ETS domain transcription factor SAP-1. J. Biol. Chem. 276:965.
    • (2001) J. Biol. Chem. , vol.276 , pp. 965
    • Galanis, A.1    Yang, S.H.2    Sharrocks, A.D.3
  • 44
    • 0033011595 scopus 로고    scopus 로고
    • Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors
    • Yang, S. H., A. Galanis, and A. D. Sharrocks. 1999. Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors. Mol. Cell. Biol. 19:4028.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4028
    • Yang, S.H.1    Galanis, A.2    Sharrocks, A.D.3
  • 45
    • 0033120052 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase mediates signal integration of TCR/CD28 costimulation in primary murine T cells
    • Zhang, J., K. V. Salojin, J. X. Gao, M. J. Cameron, I. Bergerot, and T. L. Delovitch. 1999. p38 mitogen-activated protein kinase mediates signal integration of TCR/CD28 costimulation in primary murine T cells. J. Immunol. 162:3819.
    • (1999) J. Immunol. , vol.162 , pp. 3819
    • Zhang, J.1    Salojin, K.V.2    Gao, J.X.3    Cameron, M.J.4    Bergerot, I.5    Delovitch, T.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.